Compile Data Set for Download or QSAR
maximum 50k data
Found 698 of ic50 data for polymerid = 5999
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM437709(US10617706, Example 143)
Affinity DataIC50:  3.85nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM437686(US10617706, Example 120)
Affinity DataIC50:  5.01nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM437707(US10617706, Example 141)
Affinity DataIC50:  6.09nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM50521692(CHEMBL4441013)
Affinity DataIC50:  6.10nMAssay Description:Inhibition of humanized zebrafish TDP2 using 5'-(6-FAM-NHS) as substrate preincubated for 10 mins followed by substrate addition and measured after 6...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM437708(US10617706, Example 142)
Affinity DataIC50:  6.49nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM50521699(CHEMBL4572376)
Affinity DataIC50:  6.5nMAssay Description:Inhibition of humanized zebrafish TDP2 using 5'-(6-FAM-NHS) as substrate preincubated for 10 mins followed by substrate addition and measured after 6...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM437703(US10617706, Example 137)
Affinity DataIC50:  7.25nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM50521689(CHEMBL4436202)
Affinity DataIC50:  7.30nMAssay Description:Inhibition of humanized zebrafish TDP2 using 5'-(6-FAM-NHS) as substrate preincubated for 10 mins followed by substrate addition and measured after 6...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM437685(US10617706, Example 119)
Affinity DataIC50:  8.28nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM437705(US10617706, Example 139)
Affinity DataIC50:  13.6nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM50521691(CHEMBL4587441)
Affinity DataIC50:  14nMAssay Description:Inhibition of humanized zebrafish TDP2 using 5'-(6-FAM-NHS) as substrate preincubated for 10 mins followed by substrate addition and measured after 6...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM437704(US10617706, Example 138)
Affinity DataIC50:  19.8nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM50521690(CHEMBL4520052)
Affinity DataIC50:  20nMAssay Description:Inhibition of humanized zebrafish TDP2 using 5'-(6-FAM-NHS) as substrate preincubated for 10 mins followed by substrate addition and measured after 6...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM188529(2,4-Dioxo-10-[3-(1H-tetrazol-5-yl)phenyl]pyrimido[...)
Affinity DataIC50:  25nMpH: 7.5Assay Description:Ten-million cells (1 x 107), either human, chicken DT40 wild type, or knockout for TDP2 and complemented with human TDP2, were collected, washed, and...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM437694(US10617706, Example 128)
Affinity DataIC50:  32.8nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM188529(2,4-Dioxo-10-[3-(1H-tetrazol-5-yl)phenyl]pyrimido[...)
Affinity DataIC50:  33nMpH: 7.5Assay Description:Ten-million cells (1 x 107), either human, chicken DT40 wild type, or knockout for TDP2 and complemented with human TDP2, were collected, washed, and...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM50521697(CHEMBL4468174)
Affinity DataIC50:  33nMAssay Description:Inhibition of humanized zebrafish TDP2 using 5'-(6-FAM-NHS) as substrate preincubated for 10 mins followed by substrate addition and measured after 6...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM50521687(CHEMBL4560735)
Affinity DataIC50:  33nMAssay Description:Inhibition of humanized zebrafish TDP2 using 5'-(6-FAM-NHS) as substrate preincubated for 10 mins followed by substrate addition and measured after 6...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM437692(US10617706, Example 126)
Affinity DataIC50:  33.1nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM437697(US10617706, Example 131)
Affinity DataIC50:  35nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM50521698(CHEMBL4555612)
Affinity DataIC50:  35nMAssay Description:Inhibition of humanized zebrafish TDP2 using 5'-(6-FAM-NHS) as substrate preincubated for 10 mins followed by substrate addition and measured after 6...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM50521678(CHEMBL4521151)
Affinity DataIC50:  38nMAssay Description:Inhibition of humanized zebrafish TDP2 using 5'-(6-FAM-NHS) as substrate preincubated for 10 mins followed by substrate addition and measured after 6...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM437696(US10617706, Example 130)
Affinity DataIC50:  38nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM437689(US10617706, Example 123)
Affinity DataIC50:  39nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM188529(2,4-Dioxo-10-[3-(1H-tetrazol-5-yl)phenyl]pyrimido[...)
Affinity DataIC50:  40nMpH: 7.5Assay Description:TDP2 reactions were carried out as described previously23 with the following modifications. A 18-mer single-stranded oligonucleotide DNA substrate (&...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM50518351(CHEMBL4470500)
Affinity DataIC50:  40nMAssay Description:Inhibition of humanized zebrafish TDP2 using 5'-(6-FAM-NHS) as substrate preincubated for 10 mins followed by substrate addition and measured after 6...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM50438848(CHEMBL2420480)
Affinity DataIC50:  41nMAssay Description:Inhibition of humanized zebrafish TDP2 using 5'-(6-FAM-NHS) as substrate preincubated for 10 mins followed by substrate addition and measured after 6...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM50438864(CHEMBL2420507)
Affinity DataIC50:  42nMAssay Description:Inhibition of humanized zebrafish TDP2 using 5'-(6-FAM-NHS) as substrate preincubated for 10 mins followed by substrate addition and measured after 6...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM437687(US10617706, Example 121)
Affinity DataIC50:  47nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM437699(US10617706, Example 133)
Affinity DataIC50:  59nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM50438863(10-(4-Hydroxyphenyl)-2,4-dioxo-pyrimido[4,5-b]quin...)
Affinity DataIC50:  62nMpH: 7.5Assay Description:Ten-million cells (1 x 107), either human, chicken DT40 wild type, or knockout for TDP2 and complemented with human TDP2, were collected, washed, and...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM437695(US10617706, Example 129)
Affinity DataIC50:  64.7nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM50521701(CHEMBL4457155)
Affinity DataIC50:  65nMAssay Description:Inhibition of humanized zebrafish TDP2 using 5'-(6-FAM-NHS) as substrate preincubated for 10 mins followed by substrate addition and measured after 6...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM50521688(CHEMBL4546104)
Affinity DataIC50:  70nMAssay Description:Inhibition of humanized zebrafish TDP2 using 5'-(6-FAM-NHS) as substrate preincubated for 10 mins followed by substrate addition and measured after 6...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM437693(US10617706, Example 127)
Affinity DataIC50:  70.4nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM437702(US10617706, Example 136)
Affinity DataIC50:  119nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM437698(US10617706, Example 132)
Affinity DataIC50:  119nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM50521702(CHEMBL4518508)
Affinity DataIC50:  130nMAssay Description:Inhibition of humanized zebrafish TDP2 using 5'-(6-FAM-NHS) as substrate preincubated for 10 mins followed by substrate addition and measured after 6...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM437683(US10617706, Example 117)
Affinity DataIC50:  131nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM50438863(10-(4-Hydroxyphenyl)-2,4-dioxo-pyrimido[4,5-b]quin...)
Affinity DataIC50:  140nMpH: 7.5Assay Description:TDP2 reactions were carried out as described previously23 with the following modifications. A 18-mer single-stranded oligonucleotide DNA substrate (&...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM50438863(10-(4-Hydroxyphenyl)-2,4-dioxo-pyrimido[4,5-b]quin...)
Affinity DataIC50:  140nMAssay Description:Inhibition of humanized zebrafish TDP2 using 5'-(6-FAM-NHS) as substrate preincubated for 10 mins followed by substrate addition and measured after 6...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM50521683(CHEMBL4576353)
Affinity DataIC50:  150nMAssay Description:Inhibition of humanized zebrafish TDP2 using 5'-(6-FAM-NHS) as substrate preincubated for 10 mins followed by substrate addition and measured after 6...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM437682(US10617706, Example 116)
Affinity DataIC50:  153nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM34905(1,6-dimethyl-3-propyl-pyrimido[5,4-e][1,2,4]triazi...)
Affinity DataIC50:  161nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM50438865(2,4-Dioxo-10-phenyl-pyrimido[4,5-b]quinoline-8-car...)
Affinity DataIC50:  180nMpH: 7.5Assay Description:Ten-million cells (1 x 107), either human, chicken DT40 wild type, or knockout for TDP2 and complemented with human TDP2, were collected, washed, and...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM437701(US10617706, Example 135)
Affinity DataIC50:  185nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM437675(US10617706, Example 109 | US10617706, Example 110)
Affinity DataIC50:  186nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM50521686(CHEMBL4557001)
Affinity DataIC50:  190nMAssay Description:Inhibition of humanized zebrafish TDP2 using 5'-(6-FAM-NHS) as substrate preincubated for 10 mins followed by substrate addition and measured after 6...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM437677(US10617706, Example 111)
Affinity DataIC50:  196nMAssay Description:The enzymatic activity of TDP2 was measured with a SUMO hTDP2cat fluorescence-based biochemical assay. To a black 384-well plate, 10 μL of compo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Regents Of The University Of Minnesota

US Patent
LigandPNGBDBM50521681(CHEMBL4464179)
Affinity DataIC50:  200nMAssay Description:Inhibition of humanized zebrafish TDP2 using 5'-(6-FAM-NHS) as substrate preincubated for 10 mins followed by substrate addition and measured after 6...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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