Compile Data Set for Download or QSAR
maximum 50k data
Found 6 of ic50 data for polymerid = 7112,50006541,7112
TargetAMP deaminase 1(Homo sapiens (Human))
Astrazeneca R&D

LigandPNGBDBM154584(4-[4-({[(1R)-1-(isoquinolin-8-yl)ethyl]amino}methy...)
Affinity DataIC50:  24nMpH: 7.4Assay Description:AMPD1 was added to buffer A (50 mM HEPES, 150 mM KCl, 5 mM MgCl2, and 0.5 mMglutathione [pH 7.4]) to a concentration of 10 nM. A substrate mix consis...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAMP deaminase 1(Homo sapiens (Human))
Astrazeneca R&D

LigandPNGBDBM154583(6-[4-({[(1S)-1-(isoquinolin-8-yl)ethyl]amino}methy...)
Affinity DataIC50:  38nMpH: 7.4Assay Description:AMPD1 was added to buffer A (50 mM HEPES, 150 mM KCl, 5 mM MgCl2, and 0.5 mMglutathione [pH 7.4]) to a concentration of 10 nM. A substrate mix consis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAMP deaminase 1(Oryctolagus cuniculus)
Agrevo

Curated by ChEMBL
LigandPNGBDBM50004698(CHEMBL1160282)
Affinity DataIC50:  70nMAssay Description:Inhibition of Oryctolagus cuniculus (rabbit) muscle adenylate deaminaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAMP deaminase 1(Homo sapiens (Human))
Astrazeneca R&D

LigandPNGBDBM50096172(1-Bromo-4-[2-(8-hydroxy-7,8-dihydro-6H-imidazo[4,5...)
Affinity DataIC50:  500nMAssay Description:Inhibition of human skeletal muscle AMPD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAMP deaminase 1(Homo sapiens (Human))
Astrazeneca R&D

LigandPNGBDBM154581(6-[4-({[(1R)-1-(naphthalen-1-yl)ethyl]amino}methyl...)
Affinity DataIC50:  620nMpH: 7.4Assay Description:AMPD1 was added to buffer A (50 mM HEPES, 150 mM KCl, 5 mM MgCl2, and 0.5 mMglutathione [pH 7.4]) to a concentration of 10 nM. A substrate mix consis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAMP deaminase 1(Homo sapiens (Human))
Astrazeneca R&D

LigandPNGBDBM154582(6-[4-({[(1R)-1-(isoquinolin-8-yl)ethyl]amino}methy...)
Affinity DataIC50:  9.20E+3nMpH: 7.4Assay Description:AMPD1 was added to buffer A (50 mM HEPES, 150 mM KCl, 5 mM MgCl2, and 0.5 mMglutathione [pH 7.4]) to a concentration of 10 nM. A substrate mix consis...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed