Compile Data Set for Download or QSAR
maximum 50k data
Found 1399 of ic50 data for polymerid = 8356,50000240,50001916,50003504,50006218
TargetAminopeptidase N(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50076744(CHEMBL3416733)
Affinity DataIC50: <1nMAssay Description:Inhibition of APN (unknown origin) using Ala-AMC as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Sus scrofa (Pig))
TBA

Curated by ChEMBL
LigandPNGBDBM50002035((2-Hydroxycarbamoyl-3-phenyl-propionylamino)-aceti...)
Affinity DataIC50:  1nMAssay Description:Inhibitory activity against rabbit kidney aminopeptidase using 10 nM of [3H]Leu-enkephalin as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50570849(CHEMBL4854733)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of APN (unknown origin) using A-AMC as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50570849(CHEMBL4854733)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of APN (unknown origin) using A-AMC as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Sus scrofa (Pig))
TBA

Curated by ChEMBL
LigandPNGBDBM50002022((2-Benzyl-3-hydroxycarbamoyl-propionylamino)-aceti...)
Affinity DataIC50:  2nMAssay Description:Inhibitory activity against rabbit kidney aminopeptidase using 10 nM of [3H]Leu-enkephalin as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50570850(CHEMBL4877339)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of APN (unknown origin) using A-AMC as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50570850(CHEMBL4877339)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of APN (unknown origin) using A-AMC as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Sus scrofa (Pig))
TBA

Curated by ChEMBL
LigandPNGBDBM50025913(CHEMBL16457 | [2-(Formyl-hydroxy-amino)-3-phenyl-p...)
Affinity DataIC50:  2.5nMAssay Description:Inhibitory activity against rabbit kidney aminopeptidase using 10 nM of [3H]Leu-enkephalin as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50076744(CHEMBL3416733)
Affinity DataIC50:  3.60nMAssay Description:Inhibition of APN (unknown origin) using A-AMC as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50076744(CHEMBL3416733)
Affinity DataIC50:  3.70nMAssay Description:Inhibition of APN (unknown origin) using A-AMC as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Sus scrofa (Pig))
TBA

Curated by ChEMBL
LigandPNGBDBM23971((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...)
Affinity DataIC50:  5nMAssay Description:Inhibitory activity against rabbit kidney aminopeptidase using 10 nM of [3H]Leu-enkephalin as substrateMore data for this Ligand-Target Pair
TargetAminopeptidase N(Sus scrofa (Pig))
TBA

Curated by ChEMBL
LigandPNGBDBM50020158((R,S)2-(2-Benzyl-3-hydroxycarbamoyl-propionylamino...)
Affinity DataIC50:  7.10nMAssay Description:Inhibitory activity against rabbit kidney aminopeptidase using 10 nM of [3H]Leu-enkephalin as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Sus scrofa (Pig))
TBA

Curated by ChEMBL
LigandPNGBDBM50025915(CHEMBL16622 | [2-Benzyl-3-(formyl-hydroxy-amino)-p...)
Affinity DataIC50:  8.5nMAssay Description:Inhibitory activity against rabbit kidney aminopeptidase using 10 nM of [3H]Leu-enkephalin as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50570851(CHEMBL4853049)
Affinity DataIC50:  8.60nMAssay Description:Inhibition of APN (unknown origin) using A-AMC as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50570851(CHEMBL4853049)
Affinity DataIC50:  8.70nMAssay Description:Inhibition of APN (unknown origin) using A-AMC as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50457479(CHEMBL1159812)
Affinity DataIC50:  11nMAssay Description:Inhibition of APN (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Sus scrofa (Pig))
TBA

Curated by ChEMBL
LigandPNGBDBM50002031(1-Mercaptomethyl-3-methylsulfanyl-propyl-ammonium)
Affinity DataIC50:  11nMAssay Description:Inhibition of [3H]Leu-enkephalin binding to Aminopeptidase N from hog kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50457468(CHEMBL4216928)
Affinity DataIC50:  20nMAssay Description:Inhibition of APN (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Sus scrofa (Pig))
TBA

Curated by ChEMBL
LigandPNGBDBM50002026(2-Mercapto-1-methylsulfanylmethyl-ethyl-ammonium)
Affinity DataIC50:  20nMAssay Description:Inhibition of [3H]Leu-enkephalin binding to Aminopeptidase N from hog kidneyMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Sus scrofa (Pig))
TBA

Curated by ChEMBL
LigandPNGBDBM50144944(CHEMBL3764919)
Affinity DataIC50:  20nMAssay Description:Inhibition of APN in porcine kidney microsomes preincubated for 5 mins before L-leu-p-nitroanilide substrate addition for 30 mins by plate reader ana...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50457471(CHEMBL1159811)
Affinity DataIC50:  20nMAssay Description:Inhibition of APN (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50457478(CHEMBL4208547)
Affinity DataIC50:  20nMAssay Description:Inhibition of APN (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50368599(CHEMBL1159809)
Affinity DataIC50:  20nMAssay Description:Inhibition of APN (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Sus scrofa (Pig))
TBA

Curated by ChEMBL
LigandPNGBDBM50368599(CHEMBL1159809)
Affinity DataIC50:  20nMAssay Description:Inhibition of [3H]Leu-enkephalin binding to Aminopeptidase N from hog kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50368598(CHEMBL1159810)
Affinity DataIC50:  21nMAssay Description:Inhibition of APN (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Sus scrofa (Pig))
TBA

Curated by ChEMBL
LigandPNGBDBM50368598(CHEMBL1159810)
Affinity DataIC50:  21nMAssay Description:Inhibition of [3H]Leu-enkephalin binding to Aminopeptidase N from hog kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Sus scrofa (Pig))
TBA

Curated by ChEMBL
LigandPNGBDBM50002027(1-Mercaptomethyl-3-methyl-butyl-ammonium)
Affinity DataIC50:  22nMAssay Description:Inhibition of [3H]Leu-enkephalin binding to Aminopeptidase N from hog kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Sus scrofa (Pig))
TBA

Curated by ChEMBL
LigandPNGBDBM50405949(CHEMBL2114408)
Affinity DataIC50:  23nMAssay Description:Inhibition of Aminopeptidase N activity in pig kidney with 10 nM [3H]-Leu-enkephalin as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Sus scrofa (Pig))
TBA

Curated by ChEMBL
LigandPNGBDBM50001950(2-(3,7-Diamino-2-hydroxy-heptanoylamino)-3-[2-(2-n...)
Affinity DataIC50:  24nMAssay Description:Compound was evaluated for its inhibitory potency against purified membrane bound rat brain aminopeptidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Sus scrofa (Pig))
TBA

Curated by ChEMBL
LigandPNGBDBM50002034(2-Mercapto-1-phenyl-ethyl-ammonium)
Affinity DataIC50:  25nMAssay Description:Compound was tested for inhibitory potency against aminopeptidase N from hog kidney, using [3H]Leu-enkephalin as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50457469(CHEMBL4213478)
Affinity DataIC50:  25nMAssay Description:Inhibition of APN (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Sus scrofa (Pig))
TBA

Curated by ChEMBL
LigandPNGBDBM50131276(CHEMBL328470 | N-(3-{4-[3-(7-Chloro-quinolin-4-yla...)
Affinity DataIC50:  28nMAssay Description:Inhibition of porcine kidney aminopeptidase N using Leu-pNA as substrate by microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAminopeptidase N(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50131276(CHEMBL328470 | N-(3-{4-[3-(7-Chloro-quinolin-4-yla...)
Affinity DataIC50:  28nMAssay Description:Inhibitory activity against mammalian Aminopeptidase N (APN)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Sus scrofa (Pig))
TBA

Curated by ChEMBL
LigandPNGBDBM50131276(CHEMBL328470 | N-(3-{4-[3-(7-Chloro-quinolin-4-yla...)
Affinity DataIC50:  28nMAssay Description:Inhibition of APN in porcine kidney using Leu-p-NA as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Sus scrofa (Pig))
TBA

Curated by ChEMBL
LigandPNGBDBM50036828(1-Mercaptomethyl-2-phenyl-ethyl-ammonium | 2-Amino...)
Affinity DataIC50:  30nMAssay Description:Compound was tested for inhibitory potency against aminopeptidase N from hog kidney, using [3H]Leu-enkephalin as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Sus scrofa (Pig))
TBA

Curated by ChEMBL
LigandPNGBDBM50144931(CHEMBL3764432)
Affinity DataIC50:  30nMAssay Description:Inhibition of APN in porcine kidney microsomes preincubated for 5 mins before L-leu-p-nitroanilide substrate addition for 30 mins by plate reader ana...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50036828(1-Mercaptomethyl-2-phenyl-ethyl-ammonium | 2-Amino...)
Affinity DataIC50:  30nMAssay Description:Inhibitory potency against aminopeptidase N (APN)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Sus scrofa (Pig))
TBA

Curated by ChEMBL
LigandPNGBDBM50517754(CHEMBL4456660)
Affinity DataIC50:  32nMAssay Description:Inhibition of porcine kidney microsomal APN using L-Leu-p-nitroanilide as substrate after 30 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Sus scrofa (Pig))
TBA

Curated by ChEMBL
LigandPNGBDBM50405952(CHEMBL2114407)
Affinity DataIC50:  33nMAssay Description:Inhibition of Aminopeptidase N activity in pig kidney with 10 nM [3H]-Leu-enkephalin as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Sus scrofa (Pig))
TBA

Curated by ChEMBL
LigandPNGBDBM50002019(2-tert-Butylsulfanyl-1-mercaptomethyl-ethyl-ammoni...)
Affinity DataIC50:  40nMAssay Description:Inhibition of [3H]Leu-enkephalin binding to Aminopeptidase N from hog kidneyMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM50457470(CHEMBL4204214)
Affinity DataIC50:  40nMAssay Description:Inhibition of APN (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Sus scrofa (Pig))
TBA

Curated by ChEMBL
LigandPNGBDBM50002030(2-Cyclohexyl-1-mercaptomethyl-ethyl-ammonium)
Affinity DataIC50:  45nMAssay Description:Compound was tested for inhibitory potency against aminopeptidase N from hog kidney, using [3H]Leu-enkephalin as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Sus scrofa (Pig))
TBA

Curated by ChEMBL
LigandPNGBDBM50002037(2-(4-Hydroxy-phenyl)-1-mercaptomethyl-ethyl-ammoni...)
Affinity DataIC50:  45nMAssay Description:Compound was tested for inhibitory potency against aminopeptidase N from hog kidney, using [3H]Leu-enkephalin as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Sus scrofa (Pig))
TBA

Curated by ChEMBL
LigandPNGBDBM50400532(CHEMBL2204959)
Affinity DataIC50:  50nMAssay Description:Inhibition of APN in porcine kidney microsome assessed as inhibition of L-Leu-p-nitroanilide substrate hydrolysis incubated for 5 mins before substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Sus scrofa (Pig))
TBA

Curated by ChEMBL
LigandPNGBDBM50144929(CHEMBL3764200)
Affinity DataIC50:  50nMAssay Description:Inhibition of APN in porcine kidney microsomes preincubated for 5 mins before L-leu-p-nitroanilide substrate addition for 30 mins by plate reader ana...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Sus scrofa (Pig))
TBA

Curated by ChEMBL
LigandPNGBDBM50575365(CHEMBL4851365)
Affinity DataIC50:  50nMAssay Description:Inhibition of APN in pig kidney microsomes assessed as reduction in p-nitroanilide release using L-leu-p-nitroanilide as substrate incubated for 30 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Sus scrofa (Pig))
TBA

Curated by ChEMBL
LigandPNGBDBM50002028(1-Benzyloxymethyl-2-mercapto-ethyl-ammonium)
Affinity DataIC50:  56nMAssay Description:Inhibition of [3H]Leu-enkephalin binding to Aminopeptidase N from hog kidneyMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Sus scrofa (Pig))
TBA

Curated by ChEMBL
LigandPNGBDBM50430635(CHEMBL2332525)
Affinity DataIC50:  60nMAssay Description:Inhibition of pig microsomal aminopeptidase N using L-leu-p-nitroanilide as substrate incubated for 5 mins prior to substrate addition measured after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Sus scrofa (Pig))
TBA

Curated by ChEMBL
LigandPNGBDBM50144946(CHEMBL3763918)
Affinity DataIC50:  70nMAssay Description:Inhibition of APN in porcine kidney microsomes preincubated for 5 mins before L-leu-p-nitroanilide substrate addition for 30 mins by plate reader ana...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Sus scrofa (Pig))
TBA

Curated by ChEMBL
LigandPNGBDBM50018216(2-Benzyl-3-(2-benzyl-3-hydroxycarbamoyl-propionyla...)
Affinity DataIC50:  72nMAssay Description:Inhibition of Aminopeptidase N activity in pig kidney with 10 nM [3H]-Leu-enkephalin as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 1399 total ) | Next | Last >>
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