Compile Data Set for Download or QSAR
maximum 50k data
Found 1001 of ic50 data for polymerid = 909
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM525710(US11174252, Compound 4)
Affinity DataIC50:  0.100nMAssay Description:CDK4 and CDK6: IC50 values of compounds against CDK4 and CDK6 were determined by luminescence using retinoblastoma as substrate. Kinase assays were p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM525562(US11174252, Compound 1)
Affinity DataIC50:  0.200nMAssay Description:CDK4 and CDK6: IC50 values of compounds against CDK4 and CDK6 were determined by luminescence using retinoblastoma as substrate. Kinase assays were p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM525763(US11174252, Compound 450)
Affinity DataIC50:  0.300nMAssay Description:CDK4 and CDK6: IC50 values of compounds against CDK4 and CDK6 were determined by luminescence using retinoblastoma as substrate. Kinase assays were p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM132275(US8841312, 17)
Affinity DataIC50:  0.360nMpH: 7.4 T: 2°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM132279(US8841312, 21)
Affinity DataIC50:  0.410nMpH: 7.4 T: 2°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM525754(US11174252, Compound 441)
Affinity DataIC50:  0.600nMAssay Description:CDK4 and CDK6: IC50 values of compounds against CDK4 and CDK6 were determined by luminescence using retinoblastoma as substrate. Kinase assays were p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM132303(US8841312, 46)
Affinity DataIC50:  0.75nMpH: 7.4 T: 2°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM444596(US10662186, Compound 132 | US10988476, Compound I-...)
Affinity DataIC50:  0.770nMAssay Description:1. Take 10 mM stock solution of the test compound, in 96-well compound plate, DMSO was used to dilute the compound to an initial concentration of 100...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM444596(US10662186, Compound 132 | US10988476, Compound I-...)
Affinity DataIC50:  0.770nMAssay Description:1. Take 10 mM stock solution of the test compound, in 96-well compound plate, DMSO was used to dilute the compound to an initial concentration of 100...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM448940(N-(5-(4-Ethylpiperazin-1-yl)pyridin-2-yl)-5-fluoro...)
Affinity DataIC50:  0.880nMAssay Description:Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were respectively dissolved in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM525762(US11174252, Compound 449)
Affinity DataIC50:  0.900nMAssay Description:CDK4 and CDK6: IC50 values of compounds against CDK4 and CDK6 were determined by luminescence using retinoblastoma as substrate. Kinase assays were p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM50455050(CHEMBL4208172 | US10696678, Example 18 | US1135117...)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of recombinant human full length CDK6 expressed in baculovirus infected Sf9 insect cells using histone H1 substrate after 90 mins by ADP-G...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM444581(US10662186, Compound 103 | US10662186, Compound 10...)
Affinity DataIC50:  0.970nMAssay Description:1. Take 10 mM stock solution of the test compound, in 96-well compound plate, DMSO was used to dilute the compound to an initial concentration of 100...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM444581(US10662186, Compound 103 | US10662186, Compound 10...)
Affinity DataIC50:  0.970nMAssay Description:1. Take 10 mM stock solution of the test compound, in 96-well compound plate, DMSO was used to dilute the compound to an initial concentration of 100...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM525724(US11174252, Compound 19)
Affinity DataIC50:  1nMAssay Description:CDK4 and CDK6: IC50 values of compounds against CDK4 and CDK6 were determined by luminescence using retinoblastoma as substrate. Kinase assays were p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM525721(US11174252, Compound 16)
Affinity DataIC50:  1nMAssay Description:CDK4 and CDK6: IC50 values of compounds against CDK4 and CDK6 were determined by luminescence using retinoblastoma as substrate. Kinase assays were p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM525755(US11174252, Compound 442)
Affinity DataIC50:  1nMAssay Description:CDK4 and CDK6: IC50 values of compounds against CDK4 and CDK6 were determined by luminescence using retinoblastoma as substrate. Kinase assays were p...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM556334(3-(4-((6-(5-fluoro-4-(5-fluoro-1,1-dimethyl-2,3-di...)
Affinity DataIC50:  1.02nMAssay Description:Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were respectively dissolved in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM50001539(CHEMBL3237704 | US8841312, 204)
Affinity DataIC50:  1.10nMpH: 7.4 T: 2°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM132266(US8841312, 8)
Affinity DataIC50:  1.10nMpH: 7.4 T: 2°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM444620(US10662186, Compound 202 | US10988476, Compound I-...)
Affinity DataIC50:  1.11nMAssay Description:1. Take 10 mM stock solution of the test compound, in 96-well compound plate, DMSO was used to dilute the compound to an initial concentration of 100...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM444620(US10662186, Compound 202 | US10988476, Compound I-...)
Affinity DataIC50:  1.11nMAssay Description:1. Take 10 mM stock solution of the test compound, in 96-well compound plate, DMSO was used to dilute the compound to an initial concentration of 100...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM444593(US10662186, Compound 129)
Affinity DataIC50:  1.13nMAssay Description:1. Take 10 mM stock solution of the test compound, in 96-well compound plate, DMSO was used to dilute the compound to an initial concentration of 100...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM494032(US10988476, Compound I-129)
Affinity DataIC50:  1.13nMAssay Description:1. Take 10 mM stock solution of the test compound, in 96-well compound plate, DMSO was used to dilute the compound to an initial concentration of 100...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM556327((S)-(3-(dimethylamino)pyrrolidin-1-yl)(6-(5-fluoro...)
Affinity DataIC50:  1.19nMAssay Description:Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were respectively dissolved in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM132294(US8841312, 37)
Affinity DataIC50:  1.20nMpH: 7.4 T: 2°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM444621(US10662186, Compound 203 | US10988476, Compound I-...)
Affinity DataIC50:  1.28nMAssay Description:1. Take 10 mM stock solution of the test compound, in 96-well compound plate, DMSO was used to dilute the compound to an initial concentration of 100...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM444621(US10662186, Compound 203 | US10988476, Compound I-...)
Affinity DataIC50:  1.28nMAssay Description:1. Take 10 mM stock solution of the test compound, in 96-well compound plate, DMSO was used to dilute the compound to an initial concentration of 100...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM132265(US8841312, 7)
Affinity DataIC50:  1.30nMpH: 7.4 T: 2°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM444574(US10662186, Compound 93 | US10988476, Compound I-9...)
Affinity DataIC50:  1.33nMAssay Description:1. Take 10 mM stock solution of the test compound, in 96-well compound plate, DMSO was used to dilute the compound to an initial concentration of 100...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM444574(US10662186, Compound 93 | US10988476, Compound I-9...)
Affinity DataIC50:  1.33nMAssay Description:1. Take 10 mM stock solution of the test compound, in 96-well compound plate, DMSO was used to dilute the compound to an initial concentration of 100...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM444629(US10662186, Compound 211 | US10988476, Compound I-...)
Affinity DataIC50:  1.36nMAssay Description:1. Take 10 mM stock solution of the test compound, in 96-well compound plate, DMSO was used to dilute the compound to an initial concentration of 100...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM444629(US10662186, Compound 211 | US10988476, Compound I-...)
Affinity DataIC50:  1.36nMAssay Description:1. Take 10 mM stock solution of the test compound, in 96-well compound plate, DMSO was used to dilute the compound to an initial concentration of 100...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM444575(US10662186, Compound 94 | US10988476, Compound I-9...)
Affinity DataIC50:  1.37nMAssay Description:1. Take 10 mM stock solution of the test compound, in 96-well compound plate, DMSO was used to dilute the compound to an initial concentration of 100...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM444575(US10662186, Compound 94 | US10988476, Compound I-9...)
Affinity DataIC50:  1.37nMAssay Description:1. Take 10 mM stock solution of the test compound, in 96-well compound plate, DMSO was used to dilute the compound to an initial concentration of 100...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM444573(US10662186, Compound 92 | US10988476, Compound I-9...)
Affinity DataIC50:  1.39nMAssay Description:1. Take 10 mM stock solution of the test compound, in 96-well compound plate, DMSO was used to dilute the compound to an initial concentration of 100...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM444573(US10662186, Compound 92 | US10988476, Compound I-9...)
Affinity DataIC50:  1.39nMAssay Description:1. Take 10 mM stock solution of the test compound, in 96-well compound plate, DMSO was used to dilute the compound to an initial concentration of 100...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM444595(US10662186, Compound 131 | US10988476, Compound I-...)
Affinity DataIC50:  1.41nMAssay Description:1. Take 10 mM stock solution of the test compound, in 96-well compound plate, DMSO was used to dilute the compound to an initial concentration of 100...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM444595(US10662186, Compound 131 | US10988476, Compound I-...)
Affinity DataIC50:  1.41nMAssay Description:1. Take 10 mM stock solution of the test compound, in 96-well compound plate, DMSO was used to dilute the compound to an initial concentration of 100...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM444569(US10662186, Compound 88 | US10988476, Compound I-8...)
Affinity DataIC50:  1.41nMAssay Description:1. Take 10 mM stock solution of the test compound, in 96-well compound plate, DMSO was used to dilute the compound to an initial concentration of 100...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM444569(US10662186, Compound 88 | US10988476, Compound I-8...)
Affinity DataIC50:  1.41nMAssay Description:1. Take 10 mM stock solution of the test compound, in 96-well compound plate, DMSO was used to dilute the compound to an initial concentration of 100...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM444594(US10662186, Compound 130)
Affinity DataIC50:  1.48nMAssay Description:1. Take 10 mM stock solution of the test compound, in 96-well compound plate, DMSO was used to dilute the compound to an initial concentration of 100...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM494033(US10988476, Compound I-130)
Affinity DataIC50:  1.48nMAssay Description:1. Take 10 mM stock solution of the test compound, in 96-well compound plate, DMSO was used to dilute the compound to an initial concentration of 100...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM444567(US10662186, Compound 86 | US10988476, Compound I-8...)
Affinity DataIC50:  1.49nMAssay Description:1. Take 10 mM stock solution of the test compound, in 96-well compound plate, DMSO was used to dilute the compound to an initial concentration of 100...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM444567(US10662186, Compound 86 | US10988476, Compound I-8...)
Affinity DataIC50:  1.49nMAssay Description:1. Take 10 mM stock solution of the test compound, in 96-well compound plate, DMSO was used to dilute the compound to an initial concentration of 100...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM132276(US8841312, 18)
Affinity DataIC50:  1.5nMpH: 7.4 T: 2°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM525738(US11174252, Compound 33)
Affinity DataIC50:  1.5nMAssay Description:CDK4 and CDK6: IC50 values of compounds against CDK4 and CDK6 were determined by luminescence using retinoblastoma as substrate. Kinase assays were p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM525718(US11174252, Compound 13)
Affinity DataIC50:  1.5nMAssay Description:CDK4 and CDK6: IC50 values of compounds against CDK4 and CDK6 were determined by luminescence using retinoblastoma as substrate. Kinase assays were p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM444613(US10662186, Compound 176 | US10988476, Compound I-...)
Affinity DataIC50:  1.51nMAssay Description:1. Take 10 mM stock solution of the test compound, in 96-well compound plate, DMSO was used to dilute the compound to an initial concentration of 100...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Nuvation Bio

US Patent
LigandPNGBDBM444613(US10662186, Compound 176 | US10988476, Compound I-...)
Affinity DataIC50:  1.51nMAssay Description:1. Take 10 mM stock solution of the test compound, in 96-well compound plate, DMSO was used to dilute the compound to an initial concentration of 100...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Displayed 1 to 50 (of 1001 total ) | Next | Last >>
Jump to: