Compile Data Set for Download or QSAR
maximum 50k data
Found 150 of kd data for polymerid = 1875,1880,1885,1910,1940,4105,50000007,50000047,50000102,50000382,50000649,50000651,50000652
TargetDihydrofolate reductase(Escherichia coli)
Pennsylvania State University

Curated by ChEMBL
LigandPNGBDBM18512(5-(4-chlorophenyl)-6-ethylpyrimidine-2,4-diamine |...)
Affinity DataKd:  1.40nMAssay Description:Dissociation rate constant of compound for mutant T46N Escherichia coli dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Escherichia coli)
Pennsylvania State University

Curated by ChEMBL
LigandPNGBDBM18044((2S)-2-[(4-{[(2-amino-4-oxo-1,4,7,8-tetrahydropter...)
Affinity DataKd:  220nMAssay Description:Dissociation rate constant of compound for wild type Escherichia coli dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Escherichia coli)
Pennsylvania State University

Curated by ChEMBL
LigandPNGBDBM18512(5-(4-chlorophenyl)-6-ethylpyrimidine-2,4-diamine |...)
Affinity DataKd:  13nMAssay Description:Inhibitor constant of compound for mutant T46A E. coli dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Escherichia coli)
Pennsylvania State University

Curated by ChEMBL
LigandPNGBDBM18044((2S)-2-[(4-{[(2-amino-4-oxo-1,4,7,8-tetrahydropter...)
Affinity DataKd:  243nMAssay Description:Dissociation rate constant of compound for wild type Escherichia coli dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Escherichia coli)
Pennsylvania State University

Curated by ChEMBL
LigandPNGBDBM18044((2S)-2-[(4-{[(2-amino-4-oxo-1,4,7,8-tetrahydropter...)
Affinity DataKd:  2.40E+3nMAssay Description:Dissociation rate constant of compound for mutant T46S Escherichia coli dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Escherichia coli)
Pennsylvania State University

Curated by ChEMBL
LigandPNGBDBM18512(5-(4-chlorophenyl)-6-ethylpyrimidine-2,4-diamine |...)
Affinity DataKd:  16nMAssay Description:Thermodynamic dissociation constant of compound for mutant T46A E. coli dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Escherichia coli)
Pennsylvania State University

Curated by ChEMBL
LigandPNGBDBM50022833((S)-2-{4-[(2-Amino-4-oxo-1,4,5,6,7,8-hexahydro-pte...)
Affinity DataKd:  300nMpH: 7.0 T: 2°CAssay Description:Thermodynamic Dissociation Constant for compound-Val31-dihydrofolate reductase (DHFR) complex at pH 7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Escherichia coli)
Pennsylvania State University

Curated by ChEMBL
LigandPNGBDBM50367343((2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methyl...)
Affinity DataKd:  4.80E+3nMpH: 7.0 T: 2°CAssay Description:Thermodynamic Dissociation Constant for compound-Val31-dihydrofolate reductase (DHFR) complex at pH 7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Escherichia coli)
Pennsylvania State University

Curated by ChEMBL
LigandPNGBDBM18044((2S)-2-[(4-{[(2-amino-4-oxo-1,4,7,8-tetrahydropter...)
Affinity DataKd:  6.60E+3nMpH: 7.0 T: 2°CAssay Description:Thermodynamic Dissociation Constant for compound-Val31-dihydrofolate reductase (DHFR) complex at pH 7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Gallus gallus (Chicken))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50038261(2-Amino-5-methyl-8-propyl-2,8-dihydro-3H-pyrido[2,...)
Affinity DataKd:  5.10E+3nMAssay Description:Tested for the apparent dissociation constant for binding of compound to binary NADPH complex with chicken dihydrofolate reductase using equations 11...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50038261(2-Amino-5-methyl-8-propyl-2,8-dihydro-3H-pyrido[2,...)
Affinity DataKd:  1.20E+3nMpH: 6.6Assay Description:Apparent dissociation constant at pH 6.6 for human dihydrofolate reductase in the presence of cofactor NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Gallus gallus (Chicken))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50038261(2-Amino-5-methyl-8-propyl-2,8-dihydro-3H-pyrido[2,...)
Affinity DataKd:  0.5nMAssay Description:Tested for the apparent dissociation constant for binding of compound to ternary NADPH complex with chicken dihydrofolate reductase using equation 4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50038271(2-Amino-8-ethyl-6-methyl-2,8-dihydro-3H-pyrido[2,3...)
Affinity DataKd:  7.40E+4nMpH: 6.6Assay Description:Apparent dissociation constant at pH 6.6 for Chicken dihydrofolate reductase in the presence of cofactor NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50038265(2-Amino-8-ethyl-2,8-dihydro-3H-pyrido[2,3-d]pyrimi...)
Affinity DataKd:  1.30E+4nMpH: 6.6Assay Description:Apparent dissociation constant at pH 6.6 for human dihydrofolate reductase in the presence of cofactor NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50038262(2-Amino-5,8-dimethyl-2,8-dihydro-3H-pyrido[2,3-d]p...)
Affinity DataKd:  5.10E+3nMpH: 6.6Assay Description:Apparent dissociation constant at pH 6.6 for human dihydrofolate reductase in the presence of cofactor NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50038275(2-Amino-8-methyl-2,8-dihydro-3H-pyrido[2,3-d]pyrim...)
Affinity DataKd:  2.10E+4nMpH: 6.6Assay Description:Apparent dissociation constant at pH 6.6 for human dihydrofolate reductase in the presence of cofactor NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50038263(2-Amino-8-propyl-2,8-dihydro-3H-pyrido[2,3-d]pyrim...)
Affinity DataKd:  4.00E+3nMpH: 6.6Assay Description:Apparent dissociation constant at pH 6.6 for human dihydrofolate reductase in the presence of cofactor NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50038263(2-Amino-8-propyl-2,8-dihydro-3H-pyrido[2,3-d]pyrim...)
Affinity DataKd:  1.10E+4nMpH: 6.6Assay Description:Apparent dissociation constant at pH 6.6 for Chicken dihydrofolate reductase in the presence of cofactor NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Gallus gallus (Chicken))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50038261(2-Amino-5-methyl-8-propyl-2,8-dihydro-3H-pyrido[2,...)
Affinity DataKd:  5.30E+3nMAssay Description:Tested for the apparent dissociation constant for binding of compound to binary NADPH complex with chicken dihydrofolate reductase using equation 16More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50038268(2-Amino-8-benzyl-2,8-dihydro-3H-pyrido[2,3-d]pyrim...)
Affinity DataKd:  700nMpH: 6.6Assay Description:Apparent dissociation constant at pH 6.6 for human dihydrofolate reductase in the presence of cofactor NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50038263(2-Amino-8-propyl-2,8-dihydro-3H-pyrido[2,3-d]pyrim...)
Affinity DataKd:  5.80E+3nMAssay Description:Tested for the apparent dissociation constant for binding of compound to binary NADPH complex with human dihydrofolate reductase using equations 11 a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50038263(2-Amino-8-propyl-2,8-dihydro-3H-pyrido[2,3-d]pyrim...)
Affinity DataKd:  1.70E+3nMAssay Description:Tested for the apparent dissociation constant for binding of compound to ternary NADPH complex with human dihydrofolate reductaseusing equations 15 a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50038269(2-Amino-8-isobutyl-5-methyl-2,8-dihydro-3H-pyrido[...)
Affinity DataKd:  30nMAssay Description:Tested for the apparent dissociation constant for binding of compound to ternary NADPH complex with human dihydrofolate reductase using equation 11More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50038264(2-Amino-7-methyl-8-propyl-2,8-dihydro-3H-pyrido[2,...)
Affinity DataKd:  0.600nMAssay Description:Tested for the apparent dissociation constant for binding of compound to ternary NADPH complex with human dihydrofolate reductase using equation 4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50038269(2-Amino-8-isobutyl-5-methyl-2,8-dihydro-3H-pyrido[...)
Affinity DataKd:  3.50E+3nMpH: 6.6Assay Description:Apparent dissociation constant at pH 6.6 for Chicken dihydrofolate reductase in the absence of cofactor NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50038272(2-Amino-5-methyl-8-(3-methyl-butyl)-2,8-dihydro-3H...)
Affinity DataKd:  3.30E+3nMpH: 6.6Assay Description:Apparent dissociation constant at pH 6.6 for Chicken dihydrofolate reductase in the absence of cofactor NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Gallus gallus (Chicken))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50038261(2-Amino-5-methyl-8-propyl-2,8-dihydro-3H-pyrido[2,...)
Affinity DataKd:  6.90E+3nMAssay Description:Tested for the apparent dissociation constant for binding of compound to binary NADPH complex with chicken dihydrofolate reductase using equation 11More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50038263(2-Amino-8-propyl-2,8-dihydro-3H-pyrido[2,3-d]pyrim...)
Affinity DataKd:  830nMAssay Description:Tested for the apparent dissociation constant for binding of compound to ternary NADPH complex with human dihydrofolate reductaseusing equation 11More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50038266(2-Amino-8-isopropyl-2,8-dihydro-3H-pyrido[2,3-d]py...)
Affinity DataKd:  1.90E+3nMpH: 6.6Assay Description:Apparent dissociation constant at pH 6.6 for human dihydrofolate reductase in the presence of cofactor NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50038269(2-Amino-8-isobutyl-5-methyl-2,8-dihydro-3H-pyrido[...)
Affinity DataKd:  1.60E+3nMpH: 6.6Assay Description:Apparent dissociation constant at pH 6.6 for Chicken dihydrofolate reductase in the presence of cofactor NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50038274(2-Amino-6-methyl-8-propyl-2,8-dihydro-3H-pyrido[2,...)
Affinity DataKd:  2.50E+4nMpH: 6.6Assay Description:Apparent dissociation constant at pH 6.6 for Chicken dihydrofolate reductase in the presence of cofactor NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50038273(2-Amino-7,8-dimethyl-2,8-dihydro-3H-pyrido[2,3-d]p...)
Affinity DataKd:  1.10E+3nMpH: 6.6Assay Description:Apparent dissociation constant at pH 6.6 for Chicken dihydrofolate reductase in the presence of cofactor NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50038270(2-Amino-8-isobutyl-2,8-dihydro-3H-pyrido[2,3-d]pyr...)
Affinity DataKd:  2.20E+3nMpH: 6.6Assay Description:Apparent dissociation constant at pH 6.6 for human dihydrofolate reductase in the absence of cofactor NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50038272(2-Amino-5-methyl-8-(3-methyl-butyl)-2,8-dihydro-3H...)
Affinity DataKd:  4.50E+3nMpH: 6.6Assay Description:Apparent dissociation constant at pH 6.6 for Chicken dihydrofolate reductase in the presence of cofactor NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50038270(2-Amino-8-isobutyl-2,8-dihydro-3H-pyrido[2,3-d]pyr...)
Affinity DataKd:  600nMpH: 6.6Assay Description:Apparent dissociation constant at pH 6.6 for human dihydrofolate reductase in the presence of cofactor NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50038269(2-Amino-8-isobutyl-5-methyl-2,8-dihydro-3H-pyrido[...)
Affinity DataKd:  0.100nMAssay Description:Tested for the apparent dissociation constant for binding of compound to ternary NADPH complex with human dihydrofolate reductase using equation 4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50038271(2-Amino-8-ethyl-6-methyl-2,8-dihydro-3H-pyrido[2,3...)
Affinity DataKd:  1.60E+4nMpH: 6.6Assay Description:Apparent dissociation constant at pH 6.6 for human dihydrofolate reductase in the presence of cofactor NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50038266(2-Amino-8-isopropyl-2,8-dihydro-3H-pyrido[2,3-d]py...)
Affinity DataKd:  3.40E+4nMpH: 6.6Assay Description:Apparent dissociation constant at pH 6.6 for human dihydrofolate reductase in the absence of cofactor NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50038264(2-Amino-7-methyl-8-propyl-2,8-dihydro-3H-pyrido[2,...)
Affinity DataKd:  3.40E+3nMpH: 6.6Assay Description:Apparent dissociation constant at pH 6.6 for human dihydrofolate reductase in the absence of cofactor NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50038269(2-Amino-8-isobutyl-5-methyl-2,8-dihydro-3H-pyrido[...)
Affinity DataKd:  0.200nMAssay Description:Tested for the apparent dissociation constant for binding of compound to binary NADPH complex with human dihydrofolate reductase using equation 4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50038267(2-Amino-6,8-dimethyl-2,8-dihydro-3H-pyrido[2,3-d]p...)
Affinity DataKd:  1.60E+4nMpH: 6.6Assay Description:Apparent dissociation constant at pH 6.6 for Chicken dihydrofolate reductase in the absence of cofactor NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50038264(2-Amino-7-methyl-8-propyl-2,8-dihydro-3H-pyrido[2,...)
Affinity DataKd:  2.70E+3nMAssay Description:Tested for the apparent dissociation constant for binding of compound to binary NADPH complex with human dihydrofolate reductase using equation 11More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50038260(2-Amino-8-isopropyl-6-methyl-2,8-dihydro-3H-pyrido...)
Affinity DataKd:  4.40E+4nMpH: 6.6Assay Description:Apparent dissociation constant at pH 6.6 for Chicken dihydrofolate reductase in the absence of cofactor NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50038264(2-Amino-7-methyl-8-propyl-2,8-dihydro-3H-pyrido[2,...)
Affinity DataKd:  3.40E+3nMpH: 6.6Assay Description:Apparent dissociation constant at pH 6.6 for Chicken dihydrofolate reductase in the absence of cofactor NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50038265(2-Amino-8-ethyl-2,8-dihydro-3H-pyrido[2,3-d]pyrimi...)
Affinity DataKd:  6.00E+4nMpH: 6.6Assay Description:Apparent dissociation constant at pH 6.6 for human dihydrofolate reductase in the absence of cofactor NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50038264(2-Amino-7-methyl-8-propyl-2,8-dihydro-3H-pyrido[2,...)
Affinity DataKd:  1.00E+3nMAssay Description:Tested for the apparent dissociation constant for binding of compound to ternary NADPH complex with human dihydrofolate reductase using equations 15 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50038269(2-Amino-8-isobutyl-5-methyl-2,8-dihydro-3H-pyrido[...)
Affinity DataKd:  3.00E+3nMAssay Description:Tested for the apparent dissociation constant for binding of compound to binary NADPH complex with human dihydrofolate reductase using equation 11More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50038270(2-Amino-8-isobutyl-2,8-dihydro-3H-pyrido[2,3-d]pyr...)
Affinity DataKd:  2.50E+3nMpH: 6.6Assay Description:Apparent dissociation constant at pH 6.6 for Chicken dihydrofolate reductase in the absence of cofactor NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50038264(2-Amino-7-methyl-8-propyl-2,8-dihydro-3H-pyrido[2,...)
Affinity DataKd:  450nMAssay Description:Tested for the apparent dissociation constant for binding of compound to ternary NADPH complex with human dihydrofolate reductase using equation 11More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
University Of Sydney

Curated by ChEMBL
LigandPNGBDBM50038260(2-Amino-8-isopropyl-6-methyl-2,8-dihydro-3H-pyrido...)
Affinity DataKd:  2.30E+4nMpH: 6.6Assay Description:Apparent dissociation constant at pH 6.6 for Chicken dihydrofolate reductase in the presence of cofactor NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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