Compile Data Set for Download or QSAR
maximum 50k data
Found 9 of kd data for polymerid = 1932,1933,1934,1935,1936,50000048,50000343,50002311,50004802,50004810,50006591
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50022238((R)-5-Fluoro-1-((4S,5R)-4-hydroxy-5-methylphosphat...)
Affinity DataKi:  0.00100nM Kd:  0.00100nMAssay Description:Binding affinity to amethopterin-resistant Lactobacillus casei thymidylate synthetase in presence of cofactor permitting covalent bond formationMore data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
University Of Washington

LigandPNGBDBM82167(MV1555)
Affinity DataIC50:  3.00E+4nM Kd:  5.00E+3nMpH: 7.5 T: 2°CAssay Description:A tritium release assay was used to determin the in vitro inhibitory strengths of various compounds. The inhibitory potency of human TS was determin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
University Of Washington

LigandPNGBDBM82175(MV1570)
Affinity DataIC50:  7.00E+4nM Kd:  2.00E+3nMpH: 7.5 T: 2°CAssay Description:A tritium release assay was used to determin the in vitro inhibitory strengths of various compounds. The inhibitory potency of human TS was determin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
University Of Washington

LigandPNGBDBM82174(MV1565)
Affinity DataIC50:  7.00E+4nM Kd:  1.00E+3nMpH: 7.5 T: 2°CAssay Description:A tritium release assay was used to determin the in vitro inhibitory strengths of various compounds. The inhibitory potency of human TS was determin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
University Of Washington

LigandPNGBDBM50590309(CHEMBL5196526)
Affinity DataKd:  4.40E+4nMAssay Description:Mixed type inhibition of human TS assessed as inhibitor dissociation constant by measuring changes in slope of the double reciprocal plot using dTMP ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50022238((R)-5-Fluoro-1-((4S,5R)-4-hydroxy-5-methylphosphat...)
Affinity DataKd:  10nMAssay Description:Binding affinity to amethopterin-resistant Lactobacillus casei thymidylate synthetase in presence of cofactor not permitting covalent bond formationMore data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
University Of Washington

LigandPNGBDBM50590310(CHEMBL5195943)
Affinity DataKd:  1.20E+5nMAssay Description:Mixed type inhibition of human TS assessed as inhibitor dissociation constant by measuring changes in slope of the double reciprocal plot using dTMP ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetThymidylate synthase(Homo sapiens (Human))
University Of Washington

LigandPNGBDBM50000965(CHEMBL3228982)
Affinity DataKd:  2.50E+4nMAssay Description:Binding affinity to thymidylate synthetase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
University Of Washington

LigandPNGBDBM50027923(CHEMBL1161227 | Phosphoric acid mono-[3-hydroxy-5-...)
Affinity DataKd:  1.00E+3nMAssay Description:Compound was evaluated for average apparent binding constant (Kd ) using Scatchard analysis to dTMP synthetase enzyme from chick embryoMore data for this Ligand-Target Pair