Compile Data Set for Download or QSAR
Report error Found 303 of kd data for polymerid = 236,1043,1045,1064,3619,3621,4933,50000072,50006985,50007874
TargetAcetylcholinesterase(Mouse)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149201(3,8-Diamino-6-phenyl-5-(6-{3-[2-(1,2,3,4-tetrahydr...)
Affinity DataKd:  0.000410nMAssay Description:Dissociation constant towards Acetylcholinesterase in mouseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50556952(CHEMBL4754487)
Affinity DataKd:  0.940nMAssay Description:Mixed-type inhibition of recombinant human AChE using varying concentration of acetylthiocholine iodide as substrate at 0.17 to 1.36 nM by Lineweaver...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50568793(CHEMBL4857791)
Affinity DataKd:  2.80nMAssay Description:Binding affinity to CM5 sensor chip immobilized recombinant human AChE assessed as dissociation constant at 298.15 K by surface plasmon resonance ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50568800(CHEMBL4859647)
Affinity DataKd:  3.5nMAssay Description:Binding affinity to CM5 sensor chip immobilized recombinant human AChE assessed as dissociation constant at 298.15 K by surface plasmon resonance ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50568804(CHEMBL4877719)
Affinity DataKd:  3.5nMAssay Description:Binding affinity to CM5 sensor chip immobilized recombinant human AChE assessed as dissociation constant at 298.15 K by surface plasmon resonance ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50556952(CHEMBL4754487)
Affinity DataKd:  3.60nMAssay Description:Displacement of propidium iodide from PAS-region of electric eel AChE assessed as dissociation constant by spectrofluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50568792(CHEMBL4846450)
Affinity DataKd:  4.60nMAssay Description:Binding affinity to CM5 sensor chip immobilized recombinant human AChE assessed as dissociation constant at 298.15 K by surface plasmon resonance ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50568795(CHEMBL4853698)
Affinity DataKd:  5nMAssay Description:Binding affinity to CM5 sensor chip immobilized recombinant human AChE assessed as dissociation constant at 298.15 K by surface plasmon resonance ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50568808(CHEMBL4857100)
Affinity DataKd:  5.20nMAssay Description:Binding affinity to CM5 sensor chip immobilized recombinant human AChE assessed as dissociation constant at 298.15 K by surface plasmon resonance ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM8960(2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2...)
Affinity DataKd:  8nMAssay Description:Binding affinity to CM5 sensor chip immobilized recombinant human AChE assessed as dissociation constant at 298.15 K by surface plasmon resonance ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAcetylcholinesterase(Mouse)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50546263(CHEMBL4749021)
Affinity DataKd:  10nMAssay Description:Binding affinity to mouse ACHE by fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAcetylcholinesterase(Electric eel)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM8961(CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...)
Affinity DataKd:  16nMAssay Description:Binding affinity to electric eel AChE after 24 hrs by LC/MS-SIM analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50199522((+-)-HA | (1R,9R)-1-Amino-13-eth-(E)-ylidene-11-me...)
Affinity DataKd:  17nMAssay Description:Binding affinity to CM5 sensor chip immobilized recombinant human AChE assessed as dissociation constant at 298.15 K by surface plasmon resonance ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAcetylcholinesterase(Mouse)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM8961(CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...)
Affinity DataKd:  18nMAssay Description:Dissociation constant towards Acetylcholinesterase in mouseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAcetylcholinesterase(Electric eel)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50292572(CHEMBL15910 | 3,3-dimethylbutan-2-yl methylphospho...)
Affinity DataKd:  400nMAssay Description:Binding affinity to Electric eel AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50634999(CHEMBL5555058)
Affinity DataKd:  412nMAssay Description:Mixed type non-competitive inhibition of human erythrocyte AChE using acetylthiocholine iodide as substrate assessed as dissociation constant by dixo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50633651(CHEMBL5428301)
Affinity DataKd:  440nMAssay Description:Binding affinity to paraoxon-inhibited human erythrocyte AChE assessed as dissociation constant preincubated with paraoxon for 15 mins followed by co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50633643(CHEMBL5414292)
Affinity DataKd:  480nMAssay Description:Binding affinity to DFP-inhibited human erythrocyte AChE assessed as dissociation constant preincubated with DFP for 15 mins followed by compound and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50292572(CHEMBL15910 | 3,3-dimethylbutan-2-yl methylphospho...)
Affinity DataKd:  610nMAssay Description:Binding affinity to electric eel AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50563478(CHEMBL4752879)
Affinity DataKd:  680nMAssay Description:Reactivation of paraoxon-inhibited human AChE assessed as dissociation constant incubated for 30 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50563478(CHEMBL4752879)
Affinity DataKd:  750nMAssay Description:Reactivation of parathion-inhibited human AChE assessed as dissociation constant incubated for 30 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50633643(CHEMBL5414292)
Affinity DataKd:  810nMAssay Description:Binding affinity to paraoxon-inhibited human erythrocyte AChE assessed as dissociation constant preincubated with paraoxon for 15 mins followed by co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50633649(CHEMBL5427748)
Affinity DataKd:  920nMAssay Description:Binding affinity to paraoxon-inhibited human erythrocyte AChE assessed as dissociation constant preincubated with paraoxon for 15 mins followed by co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50563478(CHEMBL4752879)
Affinity DataKd:  990nMAssay Description:Reactivation of dichlorvos-inhibited human AChE assessed as dissociation constant incubated for 30 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50563465(CHEMBL4758307)
Affinity DataKd:  990nMAssay Description:Binding affinity to paraoxon-inhibited human erythrocyte AChE assessed as dissociation constant preincubated with paraoxon for 15 mins followed by co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50563465(CHEMBL4758307)
Affinity DataKd:  1.06E+3nMAssay Description:Binding affinity to DFP-inhibited human erythrocyte AChE assessed as dissociation constant preincubated with DFP for 15 mins followed by compound and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50005563(CHEMBL434456 | CHEMBL3234587)
Affinity DataKd:  1.10E+3nMAssay Description:Reactivation of paraoxon-inhibited recombinant human AChE measured up to 10 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50462582(CHEMBL4250783)
Affinity DataKd:  1.10E+3nMAssay Description:Binding affinity to electric eel AChE after 24 hrs by LC/MS-SIM analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Mouse)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM31904(Propidium Iodide, 2 | CHEMBL345124 | Propidium | p...)
Affinity DataKd:  1.10E+3nMAssay Description:Dissociation constant towards Acetylcholinesterase in mouseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50005579(CHEMBL139148 | Obidoxime)
Affinity DataKd:  1.20E+3nMAssay Description:Reactivation of dichlorvos-inhibited human AChE assessed as dissociation constant incubated for 30 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAcetylcholinesterase(Human)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50633644(CHEMBL5437711)
Affinity DataKd:  1.22E+3nMAssay Description:Binding affinity to DFP-inhibited human erythrocyte AChE assessed as dissociation constant preincubated with DFP for 15 mins followed by compound and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50633647(CHEMBL5411628)
Affinity DataKd:  1.30E+3nMAssay Description:Binding affinity to paraoxon-inhibited human erythrocyte AChE assessed as dissociation constant preincubated with paraoxon for 15 mins followed by co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50633644(CHEMBL5437711)
Affinity DataKd:  1.71E+3nMAssay Description:Binding affinity to paraoxon-inhibited human erythrocyte AChE assessed as dissociation constant preincubated with paraoxon for 15 mins followed by co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50448131(CHEMBL3122167)
Affinity DataKd:  1.76E+3nMAssay Description:Displacement of propidium from electric eel AChE peripheral anionic site assessed as decrease in fluorescence intensity by spectrofluorometric analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50633647(CHEMBL5411628)
Affinity DataKd:  1.98E+3nMAssay Description:Binding affinity to DFP-inhibited human erythrocyte AChE assessed as dissociation constant preincubated with DFP for 15 mins followed by compound and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50241991(CHEMBL4085438)
Affinity DataKd:  2.00E+3nMAssay Description:Binding affinity to Electric eel AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50633648(CHEMBL5429288)
Affinity DataKd:  2.03E+3nMAssay Description:Binding affinity to paraoxon-inhibited human erythrocyte AChE assessed as dissociation constant preincubated with paraoxon for 15 mins followed by co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50560224(CHEMBL4751100)
Affinity DataKd:  2.03E+3nMAssay Description:Displacement of propidium iodide from PAS region of electric eel AChE by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50005579(CHEMBL139148 | Obidoxime)
Affinity DataKd:  2.10E+3nMAssay Description:Reactivation of sarin-inhibited human AChE assessed as dissociation constant incubated for 30 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAcetylcholinesterase(Electric eel)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50448130(CHEMBL3122168)
Affinity DataKd:  2.18E+3nMAssay Description:Displacement of propidium from electric eel AChE peripheral anionic site assessed as decrease in fluorescence intensity by spectrofluorometric analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50027343(CHEBI:75701 | ISOPROPYL METHYLPHOSPHONOFLUORIDATE)
Affinity DataKd:  2.20E+3nMAssay Description:Binding affinity to Electric eel AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50187216(CHEMBL3827575)
Affinity DataKd:  2.31E+3nMAssay Description:Binding affinity to sarin-inhibited hemoglobin free erythrocyte ghost human AChE using acetylcholine iodide as substrate measured for 1 hr by spectro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2017
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50633648(CHEMBL5429288)
Affinity DataKd:  2.51E+3nMAssay Description:Binding affinity to DFP-inhibited human erythrocyte AChE assessed as dissociation constant preincubated with DFP for 15 mins followed by compound and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50633650(CHEMBL5424094)
Affinity DataKd:  2.70E+3nMAssay Description:Binding affinity to paraoxon-inhibited human erythrocyte AChE assessed as dissociation constant preincubated with paraoxon for 15 mins followed by co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50633649(CHEMBL5427748)
Affinity DataKd:  2.80E+3nMAssay Description:Binding affinity to DFP-inhibited human erythrocyte AChE assessed as dissociation constant preincubated with DFP for 15 mins followed by compound and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50005579(CHEMBL139148 | Obidoxime)
Affinity DataKd:  2.84E+3nMAssay Description:Binding affinity to DFP-inhibited human erythrocyte AChE assessed as dissociation constant preincubated with DFP for 15 mins followed by compound and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetAcetylcholinesterase(Electric eel)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50448132(CHEMBL3122150)
Affinity DataKd:  3.20E+3nMAssay Description:Displacement of propidium from electric eel AChE peripheral anionic site assessed as decrease in fluorescence intensity by spectrofluorometric analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50005566(CHEMBL139018 | CHEMBL3234588)
Affinity DataKd:  3.60E+3nMAssay Description:Reactivation of paraoxon-inhibited recombinant human AChE measured up to 10 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM91726(Carbacylamidophosphate, 2b)
Affinity DataIC50: 6.20E+5nM Kd:  3.82E+3nMpH: 7.4 T: 2°CAssay Description:In-vitro and vivo using AChE and BuChE enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Barcelona

Curated by ChEMBL
LigandPNGBDBM50633653(CHEMBL5428266)
Affinity DataKd:  4.37E+3nMAssay Description:Binding affinity to paraoxon-inhibited human erythrocyte AChE assessed as dissociation constant preincubated with paraoxon for 15 mins followed by co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
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