Compile Data Set for Download or QSAR
maximum 50k data
Found 11 of kd data for polymerid = 2619,50000360
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute

Curated by ChEMBL
LigandPNGBDBM50333645(CHEMBL1756 | Estramustine phosphate)
Affinity DataKd:  8.40E+3nMAssay Description:Binding affinity to recombinant SHP2 by surface plasmon responseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens)
Emory University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50531400(CHEMBL4435688)
Affinity DataKd:  6.90E+4nMAssay Description:Binding affinity to full length wild type His-tagged SHP2 (unknown origin) by MST assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens)
Emory University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM38019(US10093646, Compound 1 | US10301278, Example 00003...)
Affinity DataKd:  1.50E+3nMAssay Description:Binding affinity to full length SHP2 E76K mutant (unknown origin) expressed in Escherichia coli BL21(DE3) competent cells by isothermal titration cal...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens)
Emory University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM38019(US10093646, Compound 1 | US10301278, Example 00003...)
Affinity DataKd:  73nMAssay Description:Binding affinity to N-terminal His tagged TEV-cleavage site fused human full length wild type SHP2 (1 to 529 residues) expressed in Escherichia coli ...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens)
Emory University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50579901(CHEMBL5087443)
Affinity DataKd:  22nMAssay Description:Binding affinity to human His-tagged SHP2 N-SH2 domain (2 to 111 residues) expressed in Escherichia coli (DE3) Rosetta2 competent cells assessed as d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens)
Emory University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM384117(1-(3-(2,3-dichlorophenyl)-1H-pyrazolo[3,4-b]pyrazi...)
Affinity DataKd:  49nMAssay Description:Binding affinity to human wild type SHP2 assessed as dissociation constant by isothermal titration calorimetry assayMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens)
Emory University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50579903(CHEMBL5082085)
Affinity DataKd:  7nMAssay Description:Binding affinity to human His-tagged SHP2 N-SH2 domain (2 to 111 residues) expressed in Escherichia coli (DE3) Rosetta2 competent cells assessed as d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens)
Emory University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50579904(CHEMBL5085273)
Affinity DataKd:  4nMAssay Description:Binding affinity to human His-tagged SHP2 N-SH2 domain (2 to 111 residues) expressed in Escherichia coli (DE3) Rosetta2 competent cells assessed as d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens)
Emory University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50579905(CHEMBL5083503)
Affinity DataKd:  15nMAssay Description:Binding affinity to human His-tagged SHP2 N-SH2 domain (2 to 111 residues) expressed in Escherichia coli (DE3) Rosetta2 competent cells assessed as d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens)
Emory University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50579906(CHEMBL5078939)
Affinity DataKd:  23nMAssay Description:Binding affinity to human His-tagged SHP2 N-SH2 domain (2 to 111 residues) expressed in Escherichia coli (DE3) Rosetta2 competent cells assessed as d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens)
Emory University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50579902(CHEMBL5072349)
Affinity DataKd:  1.60nMAssay Description:Binding affinity to human His-tagged SHP2 N-SH2 domain (2 to 111 residues) expressed in Escherichia coli (DE3) Rosetta2 competent cells assessed as d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed