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TargetBcl2-associated agonist of cell death(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 552931BDBM552931(US11344546, Example 48 | US11590126, Example 48 | ...)
Affinity DataKd:  55nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan platform: T7 phage strains displaying BCL2 proteins were grown i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
US Patent

TargetBcl2-associated agonist of cell death(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 60828BDBM60828(BDBM189459 | US9174982, 369 | ABT-199 | US10213433...)
Affinity DataKd:  55nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan platform: T7 phage strains displaying BCL2 proteins were grown i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
US Patent

TargetBcl2-associated agonist of cell death(Human)
Recurium Ip Holding

US Patent
LigandChemical structure of BindingDB Monomer ID 50270877BDBM50270877(ABT-263 | (R)-4-(4-((2-(4-chlorophenyl)-5,5-dimeth...)
Affinity DataKd:  55nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan platform: T7 phage strains displaying BCL2 proteins were grown i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
US Patent

TargetBcl2-associated agonist of cell death(Human)
Recurium Ip Holding

US Patent
LigandChemical structure of BindingDB Monomer ID 552926BDBM552926(US11318134, Example 36 | BDBM595427 | BDBM555322 |...)
Affinity DataKd:  55nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan platform: T7 phage strains displaying BCL2 proteins were grown i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
US Patent

TargetBcl2-associated agonist of cell death(Human)
Recurium Ip Holding

US Patent
LigandChemical structure of BindingDB Monomer ID 552927BDBM552927(BDBM595428 | BDBM555323 | US11318134, Example 38 |...)
Affinity DataKd:  55nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan platform: T7 phage strains displaying BCL2 proteins were grown i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
US Patent

TargetBcl2-associated agonist of cell death(Human)
Recurium Ip Holding

US Patent
LigandChemical structure of BindingDB Monomer ID 552913BDBM552913(US11344546, Example 17 | US11590126, Example 17 | ...)
Affinity DataKd:  55nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan platform: T7 phage strains displaying BCL2 proteins were grown i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
US Patent

TargetBcl2-associated agonist of cell death(Human)
Recurium Ip Holding

US Patent
LigandChemical structure of BindingDB Monomer ID 552930BDBM552930(US11344546, Example 47 | US11590126, Example 47 | ...)
Affinity DataKd:  55nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan platform: T7 phage strains displaying BCL2 proteins were grown i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
US Patent

TargetBcl2-associated agonist of cell death(Human)
Recurium Ip Holding

US Patent
LigandChemical structure of BindingDB Monomer ID 555311BDBM555311(US11344546, Example 23 | 2-(1H-pyrrolo[2,3-b]pyrid...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan platform: T7 phage strains displaying BCL2 proteins were grown i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
US Patent

TargetBcl2-associated agonist of cell death(Human)
Recurium Ip Holding

US Patent
LigandChemical structure of BindingDB Monomer ID 555312BDBM555312(US11344546, Example 25 | 2-((1H-pyrrolo[2,3-b]pyri...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan platform: T7 phage strains displaying BCL2 proteins were grown i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
US Patent

TargetBcl2-associated agonist of cell death(Human)
Recurium Ip Holding

US Patent
LigandChemical structure of BindingDB Monomer ID 555313BDBM555313(US11344546, Example 26 | 2-((1H-pyrrolo[2,3-b]pyri...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan platform: T7 phage strains displaying BCL2 proteins were grown i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
US Patent

TargetBcl2-associated agonist of cell death(Human)
Recurium Ip Holding

US Patent
LigandChemical structure of BindingDB Monomer ID 555314BDBM555314(US11344546, Example 27 | 2-((1H-pyrrolo[2,3-b]pyri...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan platform: T7 phage strains displaying BCL2 proteins were grown i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
US Patent

TargetBcl2-associated agonist of cell death(Human)
Recurium Ip Holding

US Patent
LigandChemical structure of BindingDB Monomer ID 555315BDBM555315(US11344546, Example 28 | 2-((1H-pyrrolo[2,3-b]pyri...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan platform: T7 phage strains displaying BCL2 proteins were grown i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
US Patent

TargetBcl2-associated agonist of cell death(Human)
Recurium Ip Holding

US Patent
LigandChemical structure of BindingDB Monomer ID 555316BDBM555316(US11344546, Example 30 | 2-((1H-pyrrolo[2,3-b]pyri...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan platform: T7 phage strains displaying BCL2 proteins were grown i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
US Patent

TargetBcl2-associated agonist of cell death(Human)
Recurium Ip Holding

US Patent
LigandChemical structure of BindingDB Monomer ID 555317BDBM555317(US11344546, Example 31 | 2-((1H-pyrrolo[2,3-b]pyri...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan platform: T7 phage strains displaying BCL2 proteins were grown i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
US Patent

TargetBcl2-associated agonist of cell death(Human)
Recurium Ip Holding

US Patent
LigandChemical structure of BindingDB Monomer ID 555318BDBM555318(US11344546, Example 32 | 2-((1H-pyrrolo[2,3-b]pyri...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan platform: T7 phage strains displaying BCL2 proteins were grown i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
US Patent

TargetBcl2-associated agonist of cell death(Human)
Recurium Ip Holding

US Patent
LigandChemical structure of BindingDB Monomer ID 552906BDBM552906(2-(1H-Pyrrolo[2,3-b]pyridin-5-yl-oxy)-4-(4-((2-(3-...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan platform: T7 phage strains displaying BCL2 proteins were grown i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
US Patent

TargetBcl2-associated agonist of cell death(Human)
Recurium Ip Holding

US Patent
LigandChemical structure of BindingDB Monomer ID 552907BDBM552907(2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)-4-(4-((4,4-di...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan platform: T7 phage strains displaying BCL2 proteins were grown i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
US Patent

TargetBcl2-associated agonist of cell death(Human)
Recurium Ip Holding

US Patent
LigandChemical structure of BindingDB Monomer ID 552923BDBM552923(US11318134, Example 33 | BDBM595424 | BDBM555319 |...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan platform: T7 phage strains displaying BCL2 proteins were grown i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
US Patent

TargetBcl2-associated agonist of cell death(Human)
Recurium Ip Holding

US Patent
LigandChemical structure of BindingDB Monomer ID 552908BDBM552908(US11344546, Example 10 | 2-(1H-pyrrolo[2,3-b]pyrid...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan platform: T7 phage strains displaying BCL2 proteins were grown i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
US Patent

TargetBcl2-associated agonist of cell death(Human)
Recurium Ip Holding

US Patent
LigandChemical structure of BindingDB Monomer ID 555320BDBM555320(US11344546, Example 34 | 2-((1H-pyrrolo[2,3-b]pyri...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan platform: T7 phage strains displaying BCL2 proteins were grown i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
US Patent

TargetBcl2-associated agonist of cell death(Human)
Recurium Ip Holding

US Patent
LigandChemical structure of BindingDB Monomer ID 552909BDBM552909(US11318134, Example 11 | US11344546, Example 11 | ...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan platform: T7 phage strains displaying BCL2 proteins were grown i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
US Patent

TargetBcl2-associated agonist of cell death(Human)
Recurium Ip Holding

US Patent
LigandChemical structure of BindingDB Monomer ID 552925BDBM552925(US11318134, Example 35 | BDBM595426 | 2-((1H-pyrro...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan platform: T7 phage strains displaying BCL2 proteins were grown i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
US Patent

TargetBcl2-associated agonist of cell death(Human)
Recurium Ip Holding

US Patent
LigandChemical structure of BindingDB Monomer ID 552910BDBM552910(US11344546, Example 13 | US11590126, Example 13 | ...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan platform: T7 phage strains displaying BCL2 proteins were grown i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
US Patent

TargetBcl2-associated agonist of cell death(Human)
Recurium Ip Holding

US Patent
LigandChemical structure of BindingDB Monomer ID 552911BDBM552911(US11344546, Example 15 | US11590126, Example 15 | ...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan platform: T7 phage strains displaying BCL2 proteins were grown i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
US Patent

TargetBcl2-associated agonist of cell death(Human)
Recurium Ip Holding

US Patent
LigandChemical structure of BindingDB Monomer ID 552912BDBM552912(US11344546, Example 16 | US11590126, Example 16 | ...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan platform: T7 phage strains displaying BCL2 proteins were grown i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
US Patent

TargetBcl2-associated agonist of cell death(Human)
Recurium Ip Holding

US Patent
LigandChemical structure of BindingDB Monomer ID 555324BDBM555324(US11344546, Example 39 | 2-((1H-pyrrolo[2,3-b]pyri...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan platform: T7 phage strains displaying BCL2 proteins were grown i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
US Patent

TargetBcl2-associated agonist of cell death(Human)
Recurium Ip Holding

US Patent
LigandChemical structure of BindingDB Monomer ID 552929BDBM552929(US11344546, Example 40 | US11590126, Example 40 | ...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan platform: T7 phage strains displaying BCL2 proteins were grown i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
US Patent

TargetBcl2-associated agonist of cell death(Human)
Recurium Ip Holding

US Patent
LigandChemical structure of BindingDB Monomer ID 552914BDBM552914(US11344546, Example 20 | US11590126, Example 20 | ...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan platform: T7 phage strains displaying BCL2 proteins were grown i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2022
Entry Details
US Patent

TargetBcl2-associated agonist of cell death(Mouse)
Entremed

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50262597BDBM50262597([(2S,3R,4S)-1-(Biphenyl-4-carbonyl)-4-[(biphenyl-4...)
Affinity DataKd:  7.00E+4nMAssay Description:Binding affinity to mouse Bcl-XL expressed in Escherichia coli BL21 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBcl2-associated agonist of cell death(Mouse)
Entremed

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50262594BDBM50262594((2S,3R,4S)-4-[(Biphenyl-4-carbonyl)-amino]-2-carbo...)
Affinity DataKd:  1.00E+5nMAssay Description:Binding affinity to mouse Bcl-XL expressed in Escherichia coli BL21 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBcl2-associated agonist of cell death(Mouse)
Entremed

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50262591BDBM50262591([(2S,3R,4S)-4-Allyloxycarbonylamino-1-(biphenyl-4-...)
Affinity DataKd:  1.00E+5nMAssay Description:Binding affinity to mouse Bcl-XL expressed in Escherichia coli BL21 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBcl2-associated agonist of cell death(Mouse)
Entremed

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50262593BDBM50262593(2-((2S,3R,4S)-4-(2-naphthamido)-3-hydroxy-6-((2-me...)
Affinity DataKd:  2.00E+5nMAssay Description:Binding affinity to mouse Bcl-XL expressed in Escherichia coli BL21 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBcl2-associated agonist of cell death(Mouse)
Entremed

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50262592BDBM50262592(2-((2S,3R,4S)-4-benzamido-3-hydroxy-6-((2-methoxye...)
Affinity DataKd:  3.00E+5nMAssay Description:Binding affinity to mouse Bcl-XL expressed in Escherichia coli BL21 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBcl2-associated agonist of cell death(Human)
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US Patent
LigandChemical structure of BindingDB Monomer ID 50060993BDBM50060993(4'-Fluoro-biphenyl-4-carboxylic acid | 4'-FLUORO-1...)
Affinity DataKd:  4.00E+5nMAssay Description:Binding affinity to BH3 binding groove of BclXLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBcl2-associated agonist of cell death(Mouse)
Entremed

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50262596BDBM50262596(2-((2S,3R,4S)-4-(2-naphthamido)-1-(2-naphthoyl)-3-...)
Affinity DataKd:  1.00E+6nMAssay Description:Binding affinity to mouse Bcl-XL expressed in Escherichia coli BL21 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBcl2-associated agonist of cell death(Mouse)
Entremed

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50262590BDBM50262590(2-((2S,3R,4S)-1-(2-naphthoyl)-4-(allyloxycarbonyl)...)
Affinity DataKd:  1.00E+6nMAssay Description:Binding affinity to mouse Bcl-XL expressed in Escherichia coli BL21 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBcl2-associated agonist of cell death(Human)
Recurium Ip Holding

US Patent
LigandChemical structure of BindingDB Monomer ID 50270875BDBM50270875(5,6,7,8-tetrahydro-1-naphthol | CHEMBL449132)
Affinity DataKd:  2.00E+6nMAssay Description:Binding affinity to BH3 binding groove of BclXLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBcl2-associated agonist of cell death(Mouse)
Entremed

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50263298BDBM50263298(2-((2S,3R,4S)-4-(allyloxycarbonyl)-1-benzoyl-3-hyd...)
Affinity DataKd:  4.00E+6nMAssay Description:Binding affinity to mouse Bcl-XL expressed in Escherichia coli BL21 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBcl2-associated agonist of cell death(Mouse)
Entremed

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50262595BDBM50262595(2-((2S,3R,4S)-4-benzamido-1-benzoyl-3-hydroxy-6-((...)
Affinity DataKd: >5.00E+6nMAssay Description:Binding affinity to mouse Bcl-XL expressed in Escherichia coli BL21 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed