Compile Data Set for Download or QSAR
maximum 50k data
Found 113 of kd data for polymerid = 3579
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Washington University

US Patent
LigandPNGBDBM195591(US9216974,Resorufin | US9333197, Resorufin)
Affinity DataKd:  225nMAssay Description:To determine the Ki values, fixed brain tissues prepared from 15-month-old Tg2576 mice (N=5) will be incubated for 30 min with 1 μM methoxy-X34 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Washington University

US Patent
LigandPNGBDBM195600(US9216974, WC-5-1)
Affinity DataKd:  828nMAssay Description:To determine the Ki values, fixed brain tissues prepared from 15-month-old Tg2576 mice (N=5) will be incubated for 30 min with 1 μM methoxy-X34 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Washington University

US Patent
LigandPNGBDBM195599(US9216974, WC-5-2)
Affinity DataKd:  800nMAssay Description:To determine the Ki values, fixed brain tissues prepared from 15-month-old Tg2576 mice (N=5) will be incubated for 30 min with 1 μM methoxy-X34 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Washington University

US Patent
LigandPNGBDBM195585(US9216974, WC-5-3)
Affinity DataKd:  2.38E+3nMAssay Description:To determine the Ki values, fixed brain tissues prepared from 15-month-old Tg2576 mice (N=5) will be incubated for 30 min with 1 μM methoxy-X34 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Washington University

US Patent
LigandPNGBDBM195598(US9216974, WC-5-4)
Affinity DataKd:  537nMAssay Description:To determine the Ki values, fixed brain tissues prepared from 15-month-old Tg2576 mice (N=5) will be incubated for 30 min with 1 μM methoxy-X34 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Washington University

US Patent
LigandPNGBDBM195595(US9216974, WC-5-9)
Affinity DataKd:  927nMAssay Description:To determine the Ki values, fixed brain tissues prepared from 15-month-old Tg2576 mice (N=5) will be incubated for 30 min with 1 μM methoxy-X34 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Washington University

US Patent
LigandPNGBDBM195588(US9216974, WC-5-31)
Affinity DataKd: >1.00E+4nMAssay Description:To determine the Ki values, fixed brain tissues prepared from 15-month-old Tg2576 mice (N=5) will be incubated for 30 min with 1 μM methoxy-X34 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Washington University

US Patent
LigandPNGBDBM50103964(CHEMBL3593932)
Affinity DataKd:  271nMAssay Description:Binding affinity amyloid beta (1 to 42) (unknown origin) expressed in Escherichia coli after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Washington University

US Patent
LigandPNGBDBM50463677(CHEMBL4241414)
Affinity DataKd:  1.60E+4nMAssay Description:Binding affinity to amyloid beta (1 to 42) (unknown origin) by surface plasmon resonance assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Washington University

US Patent
LigandPNGBDBM23926((E)-resveratrol | 5-[(E)-2-(4-hydroxyphenyl)etheny...)
Affinity DataKd:  3.85E+4nMAssay Description:Binding affinity to amyloid beta (1 to 42) (unknown origin) by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Washington University

US Patent
LigandPNGBDBM50497728(CHEMBL3314344)
Affinity DataKd:  0.560nMAssay Description:Binding affinity to amyloid beta42 (unknown origin) after 3 hrs by gamma countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Washington University

US Patent
LigandPNGBDBM50481119(AZD-2184 | CHEMBL570378)
Affinity DataKd:  8.40nMAssay Description:Displacement of [3H]PIB from human amyloid beta (1 to 40) fibrils after 3 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Washington University

US Patent
LigandPNGBDBM50173647((E)-4-(4-(methylamino)styryl)phenol | 4-(4-(methyl...)
Affinity DataKd:  2.40nMAssay Description:Binding affinity to Beta amyloid aggregates in Alzheimer's disease patient brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Washington University

US Patent
LigandPNGBDBM50481603(CHEMBL607562)
Affinity DataKd:  0.210nMAssay Description:Displacement of [125I-N-Methyl-4-(4-bromoanilino)phthalimide from beta-amyloid plaques isolated from Alzheimer's disease patient brainMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Washington University

US Patent
LigandPNGBDBM50484498(CHEMBL1926769)
Affinity DataKd:  91nMAssay Description:Binding affinity to human amyloid beta (1 to 42) fibril by fluorescence intensity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Washington University

US Patent
LigandPNGBDBM50484499(CHEMBL1926770)
Affinity DataKd:  167nMAssay Description:Binding affinity to human amyloid beta (1 to 42) fibril by fluorescence intensity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Washington University

US Patent
LigandPNGBDBM50484500(CHEMBL1926775)
Affinity DataKd:  192nMAssay Description:Binding affinity to human amyloid beta (1 to 42) fibril by fluorescence intensity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Washington University

US Patent
LigandPNGBDBM50100134(2-(4-Dimethylamino-phenyl)-3,6-dimethyl-benzothiaz...)
Affinity DataKd:  384nMAssay Description:Binding affinity to human amyloid beta (1 to 42) fibril by fluorescence intensity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Washington University

US Patent
LigandPNGBDBM50484501(CHEMBL1926771)
Affinity DataKd:  222nMAssay Description:Binding affinity to human amyloid beta (1 to 42) fibril by fluorescence intensity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Washington University

US Patent
LigandPNGBDBM50484502(CHEMBL1926768)
Affinity DataKd:  42nMAssay Description:Binding affinity to human amyloid beta (1 to 42) fibril by fluorescence intensity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Washington University

US Patent
LigandPNGBDBM50484503(CHEMBL1926774)
Affinity DataKd:  286nMAssay Description:Binding affinity to human amyloid beta (1 to 42) fibril by fluorescence intensity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Washington University

US Patent
LigandPNGBDBM50484504(CHEMBL1926773)
Affinity DataKd:  278nMAssay Description:Binding affinity to human amyloid beta (1 to 42) fibril by fluorescence intensity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Washington University

US Patent
LigandPNGBDBM50485994(CHEMBL2203385)
Affinity DataKd:  9.60nMAssay Description:Displacement of [3H]DMAB from amyloid beta plaque in cortex homogenate isolated from Alzheimer disease patient after 90 mins by scintillation countin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Washington University

US Patent
LigandPNGBDBM50485997(CHEMBL2203379)
Affinity DataKd:  4.5nMAssay Description:Displacement of [3H]DMAB from amyloid beta plaque in cortex homogenate isolated from Alzheimer disease patient after 90 mins by scintillation countin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Washington University

US Patent
LigandPNGBDBM50486005(CHEMBL2203394)
Affinity DataKd:  6.40nMAssay Description:Displacement of [3H]DMAB from amyloid beta plaque in cortex homogenate isolated from Alzheimer disease patient after 90 mins by scintillation countin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Washington University

US Patent
LigandPNGBDBM50129793(2-(4''-methylaminophenyl)-6-hydroxybenzothiazole |...)
Affinity DataKd:  7.20nMAssay Description:Binding affinity to beta amyloid plaque in human Alzheimer's disease brain tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Washington University

US Patent
LigandPNGBDBM50490495(CHEMBL2326893)
Affinity DataKd:  48nMAssay Description:Binding affinity to amyloid beta aggregate (unknown origin) by centrifugation methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Washington University

US Patent
LigandPNGBDBM50515565(CHEMBL4453231)
Affinity DataKd:  35nMAssay Description:Binding affinity to amyloid beta 1 to 42 (unknown origin) in PBS buffer at pH 7.4 assessed as binding constant by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Washington University

US Patent
LigandPNGBDBM50515566(CHEMBL4475538)
Affinity DataKd:  25nMAssay Description:Binding affinity to amyloid beta 1 to 42 (unknown origin) in PBS buffer at pH 7.4 assessed as binding constant by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Washington University

US Patent
LigandPNGBDBM50515567(CHEMBL4524664)
Affinity DataKd:  77nMAssay Description:Binding affinity to amyloid beta 1 to 42 (unknown origin) in PBS buffer at pH 7.4 assessed as binding constant by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Washington University

US Patent
LigandPNGBDBM50515568(CHEMBL4570231)
Affinity DataKd:  46nMAssay Description:Binding affinity to amyloid beta 1 to 42 (unknown origin) in PBS buffer at pH 7.4 assessed as binding constant by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Washington University

US Patent
LigandPNGBDBM512557(US11091444, Compound FAH-1 | US11142505, FAH-01)
Affinity DataKd:  5.00E+3nMAssay Description:β-sectretase inhibitor IV from Calbiochem (cat #565788).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Washington University

US Patent
LigandPNGBDBM512912(US11091444, Compound FAH-2)
Affinity DataKd:  8.00E+3nMAssay Description:β-sectretase inhibitor IV from Calbiochem (cat #565788).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Washington University

US Patent
LigandPNGBDBM512913(US11091444, Compound FAH-3 | US11142505, FAH #3)
Affinity DataKd:  300nMAssay Description:β-sectretase inhibitor IV from Calbiochem (cat #565788).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Washington University

US Patent
LigandPNGBDBM512916(US11091444, Compound FAH-17 | US11142505, FAH #17)
Affinity DataKd: <1.00E+3nMAssay Description:β-sectretase inhibitor IV from Calbiochem (cat #565788).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Washington University

US Patent
LigandPNGBDBM478051(US10889595, Control Example (Control sample B-Secr...)
Affinity DataKd: >5.00E+4nMAssay Description:β-sectretase inhibitor IV from Calbiochem (cat #565788).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Washington University

US Patent
LigandPNGBDBM50587291(CHEMBL5092830)
Affinity DataKd:  1.20E+7nMAssay Description:Binding affinity to CM-5 sensor chip immobilized beta-amyloid monomer (1 to 42) (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Washington University

US Patent
LigandPNGBDBM50587299(CHEMBL5077020)
Affinity DataKd:  1.55E+6nMAssay Description:Binding affinity to CM-5 sensor chip immobilized beta-amyloid monomer (1 to 42) (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Washington University

US Patent
LigandPNGBDBM50587301(CHEMBL5094225)
Affinity DataKd:  5.16E+4nMAssay Description:Binding affinity to CM-5 sensor chip immobilized beta-amyloid monomer (1 to 42) (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Washington University

US Patent
LigandPNGBDBM50593987(CHEMBL5195109)
Affinity DataKd:  6.50E+5nMAssay Description:Binding affinity to 5R to 22E residues of 15N-labelled amyloid beta (1 to 42) (unknown origin) expressed in Escherichia coli BL21 (DE3)-pLysS cells a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Washington University

US Patent
LigandPNGBDBM50593988(CHEMBL5207452)
Affinity DataKd:  5.74E+6nMAssay Description:Binding affinity to 5R to 22E residues of 15N-labelled amyloid beta (1 to 42) (unknown origin) expressed in Escherichia coli BL21 (DE3)-pLysS cells a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Washington University

US Patent
LigandPNGBDBM50598535(CHEMBL5197068)
Affinity DataKd:  6.27E+3nMAssay Description:Binding affinity to amyloid beta (1 to 40) (unknown origin) fibrilsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Washington University

US Patent
LigandPNGBDBM64709(2-[(1E,3E)-4-(4-Dimethylamino-phenyl)-buta-1,3-die...)
Affinity DataKd:  1.22E+3nMAssay Description:Binding affinity to amyloid beta (1 to 40) (unknown origin) fibrilsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Washington University

US Patent
LigandPNGBDBM50402407(CHEMBL2207756)
Affinity DataKd:  8.31E+3nMAssay Description:Binding affinity to amyloid beta (1 to 40) (unknown origin) fibrilsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Washington University

US Patent
LigandPNGBDBM50402408(CHEMBL2203332)
Affinity DataKd:  930nMAssay Description:Binding affinity to amyloid beta (1 to 40) (unknown origin) fibrilsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Washington University

US Patent
LigandPNGBDBM50598536(CHEMBL5183943)
Affinity DataKd:  39nMAssay Description:Binding affinity to amyloid beta (1 to 40) (unknown origin) fibrilsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Washington University

US Patent
LigandPNGBDBM50598537(CHEMBL5175387)
Affinity DataKd:  1.94E+5nMAssay Description:Binding affinity to amyloid beta (1 to 40) (unknown origin) fibrilsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Washington University

US Patent
LigandPNGBDBM50598538(CHEMBL5206461)
Affinity DataKd:  4.59E+5nMAssay Description:Binding affinity to amyloid beta (1 to 40) (unknown origin) fibrilsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Washington University

US Patent
LigandPNGBDBM50598539(CHEMBL5196550)
Affinity DataKd:  1.31E+4nMAssay Description:Binding affinity to amyloid beta (1 to 40) (unknown origin) fibrilsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Washington University

US Patent
LigandPNGBDBM50598540(CHEMBL5171920)
Affinity DataKd:  9.20E+4nMAssay Description:Binding affinity to amyloid beta (1 to 40) (unknown origin) fibrilsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
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