Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wellcome Research Laboratories
Curated by ChEMBL
Wellcome Research Laboratories
Curated by ChEMBL
Affinity DataKd: 1.80nMAssay Description:Binding affinity against 5-hydroxytryptamine 1 receptor using rabbit jugular vein assay in the absence of endotheliumMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wellcome Research Laboratories
Curated by ChEMBL
Wellcome Research Laboratories
Curated by ChEMBL
Affinity DataKd: 0.0800nMAssay Description:Displacement of [3H]WAY600135 from human 5HT1A stably expressed in HEK293T cell membrane incubated for 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
University Of Pennsylvania
Curated by ChEMBL
University Of Pennsylvania
Curated by ChEMBL
Affinity DataKd: 0.100nMAssay Description:In vitro binding affinity for 5-hydroxytryptamine 1A receptor was determined by measuring specific inhibition of [125I]-binding to rat hippocampal me...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
University Of Pennsylvania
Curated by ChEMBL
University Of Pennsylvania
Curated by ChEMBL
Affinity DataKd: 0.400nMAssay Description:Inhibition of binding of [125I]-8-OH-PIPAT ligand to 5-hydroxytryptamine 1A receptor of rat hippocampal homogenatesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
University Of Pennsylvania
Curated by ChEMBL
University Of Pennsylvania
Curated by ChEMBL
Affinity DataKd: 0.300nMAssay Description:The binding of [125I]MPPI ligand to 5-hydroxytryptamine 1A receptor of rat hippocampal homogenatesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wellcome Research Laboratories
Curated by ChEMBL
Wellcome Research Laboratories
Curated by ChEMBL
Affinity DataKd: 50nMAssay Description:Binding affinity to human 5HT1A receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wellcome Research Laboratories
Curated by ChEMBL
Wellcome Research Laboratories
Curated by ChEMBL
Affinity DataKd: 28nMAssay Description:Binding affinity to human 5HT1A receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wellcome Research Laboratories
Curated by ChEMBL
Wellcome Research Laboratories
Curated by ChEMBL
Affinity DataKd: 3.00E+4nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wellcome Research Laboratories
Curated by ChEMBL
Wellcome Research Laboratories
Curated by ChEMBL
Affinity DataKd: 50.1nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wellcome Research Laboratories
Curated by ChEMBL
Wellcome Research Laboratories
Curated by ChEMBL
Affinity DataKd: 501nMAssay Description:Binding affinity for 5-hydroxytryptamine 1A receptor in piglet hippocampus using [3H]8-OH-DPATMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wellcome Research Laboratories
Curated by ChEMBL
Wellcome Research Laboratories
Curated by ChEMBL
Affinity DataKd: 3.16E+3nMAssay Description:Binding affinity for 5-hydroxytryptamine 1A receptor in piglet hippocampus using [3H]8-OH-DPATMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wellcome Research Laboratories
Curated by ChEMBL
Wellcome Research Laboratories
Curated by ChEMBL
Affinity DataKd: 3.20nMAssay Description:Binding affinity for 5-hydroxytryptamine 1A receptor was determinedMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wellcome Research Laboratories
Curated by ChEMBL
Wellcome Research Laboratories
Curated by ChEMBL
Affinity DataKd: 0.316nMAssay Description:Binding affinity for 5-hydroxytryptamine 1A receptor was determinedMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wellcome Research Laboratories
Curated by ChEMBL
Wellcome Research Laboratories
Curated by ChEMBL
Affinity DataKd: 794nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor in pig frontal cortex membranes using [8H]-OH-DPATMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wellcome Research Laboratories
Curated by ChEMBL
Wellcome Research Laboratories
Curated by ChEMBL
Affinity DataKd: <1.00E+4nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor in pig frontal cortex membranes using [8H]-OH-DPATMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wellcome Research Laboratories
Curated by ChEMBL
Wellcome Research Laboratories
Curated by ChEMBL
Affinity DataKd: 0.200nMAssay Description:Binding affinity to 5-HT1A receptor (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wellcome Research Laboratories
Curated by ChEMBL
Wellcome Research Laboratories
Curated by ChEMBL
Affinity DataKd: 0.340nMAssay Description:Binding affinity to 5-HT1A receptor (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wellcome Research Laboratories
Curated by ChEMBL
Wellcome Research Laboratories
Curated by ChEMBL
Affinity DataKd: 0.0800nMAssay Description:Displacement of [3H]WAY600135 from human 5HT1A stably expressed in HEK293T cell membrane incubated for 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wellcome Research Laboratories
Curated by ChEMBL
Wellcome Research Laboratories
Curated by ChEMBL
Affinity DataKd: 0.0800nMAssay Description:Displacement of [3H]WAY600135 from human 5HT1A stably expressed in HEK293T cell membrane incubated for 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Wellcome Research Laboratories
Curated by ChEMBL
Wellcome Research Laboratories
Curated by ChEMBL
Affinity DataKd: 0.0800nMAssay Description:Displacement of [3H]WAY600135 from human 5HT1A stably expressed in HEK293T cell membrane incubated for 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
University Of Pennsylvania
Curated by ChEMBL
University Of Pennsylvania
Curated by ChEMBL
Affinity DataKd: 2.5nMAssay Description:Binding affinity against the site labelled by the 5-hydroxytryptamine 1A receptor agonist [3H]- 8-OH-DPATMore data for this Ligand-Target Pair