Found 135 of kd data for polymerid = 3744,3987 TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research
Walter And Eliza Hall Institute Of Medical Research
Affinity DataIC50: 7.10nM Kd: 1.40nMpH: 7.4Assay Description:The protocols for tight and weak binders were described in Biacore S51 assay set-up with a flow rate of 30 µL/min. For His-Bcl-2 protein assays...More data for this Ligand-Target Pair
Affinity DataIC50: 270nM Kd: 110nMpH: 7.4 T: 2°CAssay Description:FPAs were performed using various concentrations of GST-Bcl-2 family proteins, incubated with FITC-conjugated peptide substrates in the presence of i...More data for this Ligand-Target Pair
Affinity DataIC50: 760nM Kd: 110nMpH: 7.4 T: 2°CAssay Description:FPAs were performed using various concentrations of GST-Bcl-2 family proteins, incubated with FITC-conjugated peptide substrates in the presence of i...More data for this Ligand-Target Pair
Affinity DataIC50: 930nM Kd: 120nMpH: 7.4 T: 2°CAssay Description:FPAs were performed using various concentrations of GST-Bcl-2 family proteins, incubated with FITC-conjugated peptide substrates in the presence of i...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nM Kd: 850nMpH: 7.4 T: 2°CAssay Description:FPAs were performed using various concentrations of GST-Bcl-2 family proteins, incubated with FITC-conjugated peptide substrates in the presence of i...More data for this Ligand-Target Pair
Affinity DataIC50: 3.50E+3nM Kd: 410nMpH: 7.4 T: 2°CAssay Description:FPAs were performed using various concentrations of GST-Bcl-2 family proteins, incubated with FITC-conjugated peptide substrates in the presence of i...More data for this Ligand-Target Pair
Affinity DataIC50: 3.70E+3nM Kd: 1.70E+3nMpH: 7.4 T: 2°CAssay Description:FPAs were performed using various concentrations of GST-Bcl-2 family proteins, incubated with FITC-conjugated peptide substrates in the presence of i...More data for this Ligand-Target Pair
TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research
Walter And Eliza Hall Institute Of Medical Research
Affinity DataIC50: 5.10E+3nM Kd: 1.98E+4nMAssay Description:In order to figure whether these compounds were capable of displacing the interactions between Bci-XL and it's pro-apoptotic counterparts, it was...More data for this Ligand-Target Pair
TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research
Walter And Eliza Hall Institute Of Medical Research
Affinity DataKd: 850nMpH: 2.2 T: 2°CAssay Description:A concentration series of each compound was injected at a flow rate of 90 µL/min over three spots at 25°C. The times allowed for compound a...More data for this Ligand-Target Pair
TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research
Walter And Eliza Hall Institute Of Medical Research
Affinity DataKd: 230nMpH: 2.2 T: 2°CAssay Description:A concentration series of each compound was injected at a flow rate of 90 µL/min over three spots at 25°C. The times allowed for compound a...More data for this Ligand-Target Pair
Affinity DataKd: 2.80E+3nMAssay Description:The synthesized compounds of Formula I may be screened by one-dimensional 1H nuclear magnetic resonance spectroscopy (1D-1H NMR) binding assays again...More data for this Ligand-Target Pair
Affinity DataKd: 1.50E+3nMAssay Description:The synthesized compounds of Formula I may be screened by one-dimensional 1H nuclear magnetic resonance spectroscopy (1D-1H NMR) binding assays again...More data for this Ligand-Target Pair
Affinity DataKd: 2.50E+3nMAssay Description:The synthesized compounds of Formula I may be screened by one-dimensional 1H nuclear magnetic resonance spectroscopy (1D-1H NMR) binding assays again...More data for this Ligand-Target Pair
Affinity DataKd: 450nMAssay Description:The synthesized compounds of Formula I may be screened by one-dimensional 1H nuclear magnetic resonance spectroscopy (1D-1H NMR) binding assays again...More data for this Ligand-Target Pair
Affinity DataKd: 1.70E+3nMpH: 7.4Assay Description:Titrations were performed using a VP-ITC or ITC200 calorimeter from Microcal (Northampton, Mass.). BCL-XL was used at concentrations between 25 and 1...More data for this Ligand-Target Pair
Affinity DataKd: 170nMpH: 7.4Assay Description:Titrations were performed using a VP-ITC or ITC200 calorimeter from Microcal (Northampton, Mass.). BCL-XL was used at concentrations between 25 and 1...More data for this Ligand-Target Pair
Affinity DataKd: 40nMpH: 7.4Assay Description:Titrations were performed using a VP-ITC or ITC200 calorimeter from Microcal (Northampton, Mass.). BCL-XL was used at concentrations between 25 and 1...More data for this Ligand-Target Pair
Affinity DataKd: 2.75E+3nMpH: 7.4Assay Description:Titrations were performed using a VP-ITC or ITC200 calorimeter from Microcal (Northampton, Mass.). BCL-XL was used at concentrations between 25 and 1...More data for this Ligand-Target Pair
TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Walter And Eliza Hall Institute Of Medical Research
Walter And Eliza Hall Institute Of Medical Research
Affinity DataKd: 25.5nMpH: 7.4 T: 2°CAssay Description:One hundred microliters of a 600 ng/mL solution of biotin-BID (Biotin-lc-EDIIRNIARHLAQVGDSMDR-NH2, where lc indicates a hydrocarbon chain of six meth...More data for this Ligand-Target Pair
Affinity DataKd: 2.00E+3nMAssay Description:Binding affinity to Bcl-XL by isothermal titration calorimetric assayMore data for this Ligand-Target Pair
Affinity DataKd: 2.40E+3nMAssay Description:Binding affinity to Bcl-XL by isothermal titration calorimetric assayMore data for this Ligand-Target Pair
Affinity DataKd: 4.20nMAssay Description:Binding affinity to Bcl-XlMore data for this Ligand-Target Pair
Affinity DataKd: 38nMAssay Description:Binding affinity to GST-tagged Bcl-Xl (unknown origin) by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKd: 10nMAssay Description:Binding affinity to GST-tagged Bcl-Xl (unknown origin) by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKd: <5nMAssay Description:Binding affinity to GST-tagged Bcl-Xl (unknown origin) by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKd: 4.00E+6nMAssay Description:Binding affinity to BCL-XL (unknown origin)More data for this Ligand-Target Pair
Affinity DataKd: 4.30E+6nMAssay Description:Inhibition of GST-tagged Bcl-xL (unknown origin) measured after 1 hr incubation by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKd: 3.00E+5nMAssay Description:Inhibition of GST-tagged Bcl-xL (unknown origin) measured after 1 hr incubation by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKd: 5.28E+5nMAssay Description:Inhibition of interaction between GST-tagged Bcl-xl and Bak by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.08E+7nMAssay Description:Inhibition of interaction between GST-tagged Bcl-xl and Bak by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKd: 3.77E+5nMAssay Description:Inhibition of interaction between GST-tagged Bcl-xl and Bak by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.71E+3nMAssay Description:Inhibition of interaction between GST-tagged Bcl-xl and Bak by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.83E+6nMAssay Description:Inhibition of interaction between Bcl-xl and Bak by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKd: 3.99E+5nMAssay Description:Inhibition of interaction between Bcl-xl and Bak by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKd: 3.38E+5nMAssay Description:Inhibition of interaction between Bcl-xl and Bak by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKd: 2.70E+6nMAssay Description:Binding affinity to 6xHis-tagged human Bcl-xLMore data for this Ligand-Target Pair
Affinity DataKd: 9.50E+3nMAssay Description:Binding affinity to human Bcl-XL by surface plasma resonance based biosensor systemMore data for this Ligand-Target Pair
Affinity DataKd: 9.63E+4nMAssay Description:Binding affinity to human Bcl-XL by surface plasma resonance based biosensor systemMore data for this Ligand-Target Pair
Affinity DataKd: 3.85E+4nMAssay Description:Binding affinity to human Bcl-XL by surface plasma resonance based biosensor systemMore data for this Ligand-Target Pair
Affinity DataKd: 4.50E+5nMAssay Description:Binding affinity to Bcl-XL by NMR titration assayMore data for this Ligand-Target Pair
Affinity DataKd: 7.00E+5nMAssay Description:Binding affinity to Bcl-XL by NMR titration assayMore data for this Ligand-Target Pair
Affinity DataKd: 5.00E+6nMAssay Description:Binding affinity to Bcl-XL by NMR titration assayMore data for this Ligand-Target Pair
Affinity DataKd: 5.00E+5nMAssay Description:Binding affinity to Bcl-XL by NMR titration assayMore data for this Ligand-Target Pair
Affinity DataKd: 2.80E+3nMAssay Description:Binding affinity Bcl-xL by isothermal titration calorimetry assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.50E+3nMAssay Description:Binding affinity Bcl-xL by isothermal titration calorimetry assayMore data for this Ligand-Target Pair
Affinity DataKd: 2.50E+3nMAssay Description:Binding affinity Bcl-xL by isothermal titration calorimetry assayMore data for this Ligand-Target Pair
Affinity DataKd: 450nMAssay Description:Binding affinity Bcl-xL by isothermal titration calorimetry assayMore data for this Ligand-Target Pair
Affinity DataKd: 0.370nMAssay Description:Binding affinity to Bcl-XlMore data for this Ligand-Target Pair
Affinity DataKd: 3.00E+5nMAssay Description:Binding affinity to Bcl-xL by 2D- NOESY analysisMore data for this Ligand-Target Pair
Affinity DataKd: 4.30E+6nMAssay Description:Binding affinity to Bcl-xL by 2D- NOESY analysisMore data for this Ligand-Target Pair
