Compile Data Set for Download or QSAR
Report error Found 29 of kd data for polymerid = 49000704,49000706,49000707,49000708
TargetCysteinyl leukotriene receptor 1(Guinea pig)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50403196BDBM50403196(CHEMBL289880)
Affinity DataKd:  4nMAssay Description:Compound was evaluated for its antagonist affinity at 0.1 uM on guinea-pig trachea rings against LTD4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article

TargetCysteinyl leukotriene receptor 1(Guinea pig)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50064062BDBM50064062(6-chloro-4-oxo-2-(3-(2-(quinolin-2-yl)vinyl)phenyl...)
Affinity DataKd:  11nMAssay Description:In vitro affinity for CysLT1 receptors on guinea pig lung membranes, measured by displacement of [3H]LTD4.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Guinea pig)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50064078BDBM50064078(6-Bromo-2-[3-(7-chloro-quinolin-2-ylmethoxy)-pheny...)
Affinity DataKd:  12nMAssay Description:In vitro affinity for CysLT1 receptors on guinea pig lung membranes, measured by displacement of [3H]LTD4.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Guinea pig)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50064060BDBM50064060(6-Methyl-4-oxo-2-[3-((E)-2-quinolin-2-yl-vinyl)-ph...)
Affinity DataKd:  13nMAssay Description:In vitro affinity for CysLT1 receptors on guinea pig lung membranes, measured by displacement of [3H]LTD4.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Guinea pig)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50064074BDBM50064074(4-Oxo-2-[3-((E)-2-quinolin-2-yl-vinyl)-phenyl]-4H-...)
Affinity DataKd:  17nMAssay Description:In vitro affinity for CysLT1 receptors on guinea pig lung membranes, measured by displacement of [3H]LTD4.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Guinea pig)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50064072BDBM50064072(4-Oxo-2-[3-(quinolin-2-ylmethoxy)-phenyl]-4H-chrom...)
Affinity DataKd:  17nMAssay Description:In vitro affinity for CysLT1 receptors on guinea pig lung membranes, measured by displacement of [3H]LTD4.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Guinea pig)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50064068BDBM50064068(6-bromo-4-oxo-2-(3-(2-(quinolin-2-yl)vinyl)phenyl)...)
Affinity DataKd:  17nMAssay Description:In vitro affinity for CysLT1 receptors on guinea pig lung membranes, measured by displacement of [3H]LTD4.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Guinea pig)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50064064BDBM50064064(6-bromo-4-oxo-2-(3-(quinolin-2-ylmethoxy)phenyl)-4...)
Affinity DataKd:  31nMAssay Description:In vitro affinity for CysLT1 receptors on guinea pig lung membranes, measured by displacement of [3H]LTD4.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Guinea pig)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50064066BDBM50064066(2-[3-(Benzothiazol-2-ylmethoxy)-phenyl]-6-bromo-4-...)
Affinity DataKd:  79nMAssay Description:In vitro affinity for CysLT1 receptors on guinea pig lung membranes, measured by displacement of [3H]LTD4.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Guinea pig)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50064061BDBM50064061(6-Bromo-4-oxo-2-[3-(quinazolin-2-ylmethoxy)-phenyl...)
Affinity DataKd:  101nMAssay Description:In vitro affinity for CysLT1 receptors on guinea pig lung membranes, measured by displacement of [3H]LTD4.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Guinea pig)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50064075BDBM50064075(6-Fluoro-4-oxo-2-[3-((E)-2-quinolin-2-yl-vinyl)-ph...)
Affinity DataKd:  127nMAssay Description:In vitro affinity for CysLT1 receptors on guinea pig lung membranes, measured by displacement of [3H]LTD4.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Guinea pig)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50064070BDBM50064070(6-Bromo-2-[3-(1-methyl-1H-benzoimidazol-2-ylmethox...)
Affinity DataKd:  210nMAssay Description:In vitro affinity for CysLT1 receptors on guinea pig lung membranes, measured by displacement of [3H]LTD4.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Guinea pig)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50064077BDBM50064077(4-oxo-2-(4-(2-(quinolin-2-yl)vinyl)phenyl)-4H-chro...)
Affinity DataKd:  270nMAssay Description:In vitro affinity for CysLT1 receptors on guinea pig lung membranes, measured by displacement of [3H]LTD4.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Guinea pig)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50064080BDBM50064080(2-[3-((E)-2-Quinolin-2-yl-vinyl)-phenyl]-6-(1H-tet...)
Affinity DataKd:  307nMAssay Description:In vitro affinity for CysLT1 receptors on guinea pig lung membranes, measured by displacement of [3H]LTD4.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Guinea pig)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50064076BDBM50064076(6-bromo-4-oxo-N-(phenylsulfonyl)-2-(4-(quinolin-2-...)
Affinity DataKd:  382nMAssay Description:In vitro affinity for CysLT1 receptors on guinea pig lung membranes, measured by displacement of [3H]LTD4.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Guinea pig)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50064079BDBM50064079(4-Oxo-2-[3-((E)-2-quinolin-2-yl-vinyl)-phenyl]-4H-...)
Affinity DataKd:  408nMAssay Description:In vitro affinity for CysLT1 receptors on guinea pig lung membranes, measured by displacement of [3H]LTD4.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Guinea pig)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50064067BDBM50064067(6-Bromo-4-oxo-2-[4-(quinolin-2-ylmethoxy)-phenyl]-...)
Affinity DataKd:  504nMAssay Description:In vitro affinity for CysLT1 receptors on guinea pig lung membranes, measured by displacement of [3H]LTD4.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Guinea pig)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50064071BDBM50064071(4-Oxo-2-[4-(quinolin-2-ylmethoxy)-phenyl]-4H-chrom...)
Affinity DataKd:  526nMAssay Description:In vitro affinity for CysLT1 receptors on guinea pig lung membranes, measured by displacement of [3H]LTD4.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Guinea pig)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50064069BDBM50064069(4-Oxo-2-[4-(quinazolin-2-ylmethoxy)-phenyl]-4H-chr...)
Affinity DataKd:  1.10E+3nMAssay Description:In vitro affinity for CysLT1 receptors on guinea pig lung membranes, measured by displacement of [3H]LTD4.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Guinea pig)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50006812BDBM50006812(7-[3-(4-Acetyl-3-hydroxy-2-propyl-phenoxy)-2-hydro...)
Affinity DataKd:  1.12E+3nMAssay Description:Dissociation constant was determined against Cysteinyl leukotriene D4 receptor of guinea pig lung membranes using radioligand binding assays.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Guinea pig)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50064081BDBM50064081(6-Bromo-2-[3-(naphthalen-2-ylmethoxy)-phenyl]-4-ox...)
Affinity DataKd:  1.13E+3nMAssay Description:In vitro affinity for CysLT1 receptors on guinea pig lung membranes, measured by displacement of [3H]LTD4.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Guinea pig)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50064073BDBM50064073(4-Oxo-2-[3-((E)-2-quinolin-2-yl-vinyl)-phenyl]-4H-...)
Affinity DataKd:  1.73E+3nMAssay Description:In vitro affinity for CysLT1 receptors on guinea pig lung membranes, measured by displacement of [3H]LTD4.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Guinea pig)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50064082BDBM50064082(4-oxo-2-(3-(2-(quinolin-2-yl)vinyl)phenyl)-4H-chro...)
Affinity DataKd:  1.75E+3nMAssay Description:In vitro affinity for CysLT1 receptors on guinea pig lung membranes, measured by displacement of [3H]LTD4.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Guinea pig)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50031679BDBM50031679(7-[3-(4-Benzhydrylidene-piperidin-1-yl)-propoxy]-2...)
Affinity DataKd:  2.34E+3nMAssay Description:Dissociation constant was determined against Cysteinyl leukotriene D4 receptor of guinea pig lung membranes using radioligand binding assays.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Guinea pig)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50031686BDBM50031686(6-[3-(4-Benzhydrylidene-piperidin-1-yl)-propoxy]-4...)
Affinity DataKd:  4.27E+3nMAssay Description:Dissociation constant was determined against Cysteinyl leukotriene D4 receptor of guinea pig lung membranes using radioligand binding assays.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Guinea pig)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50064063BDBM50064063(6-Chloro-2-[3-((E)-2-quinolin-2-yl-vinyl)-phenyl]-...)
Affinity DataKd:  1.10E+4nMAssay Description:In vitro affinity for CysLT1 receptors on guinea pig lung membranes, measured by displacement of [3H]LTD4.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Guinea pig)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50009075BDBM50009075(CHEMBL22033 | ICI 198615 | [1-(4-Benzenesulfonylam...)
Affinity DataKd:  3.01E+4nMAssay Description:Dissociation constant for CysLT1 receptor was determined by the displacement of [3H]LTD4 from guinea pig lung membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetCysteinyl leukotriene receptor 1(Guinea pig)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50064065BDBM50064065(2-(4-Benzyloxy-phenyl)-4-oxo-4H-chromene-8-carboxy...)
Affinity DataKd:  5.50E+4nMAssay Description:In vitro affinity for CysLT1 receptors on guinea pig lung membranes, measured by displacement of [3H]LTD4.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Guinea pig)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50023198BDBM50023198(CHEMBL21333 | N-(4-oxo-2-(1H-tetrazol-5-yl)-4H-chr...)
Affinity DataKd:  2.14E+5nMAssay Description:Dissociation constant for CysLT1 receptor was determined by the displacement of [3H]LTD4 from guinea pig lung membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article
PDB3D3D Structure (crystal)