Compile Data Set for Download or QSAR
maximum 50k data
Found 16 of kd data for polymerid = 4936,49000889,49000994,49000996
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
George Washington University Medical Center

Curated by ChEMBL
LigandPNGBDBM81982(CAS_97-39-2 | DITOLYLGUANIDINE | DTG | Di-o-tolylg...)
Affinity DataKd:  38.2nMAssay Description:Binding affinity against MCF cells in the membrane preparation using radioligand binding assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
George Washington University Medical Center

Curated by ChEMBL
LigandPNGBDBM50601684(CHEMBL5169925)
Affinity DataKd:  1.24E+4nMAssay Description:Binding affinity to sigma 1 receptor (unknown origin) assessed as dissociation constant by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
George Washington University Medical Center

Curated by ChEMBL
LigandPNGBDBM50035131((+)-(6R,11S)-6,11-dimethyl-3-(3-methyl-but-2-enyl)...)
Affinity DataKd:  34.5nMAssay Description:Binding affinity to Sigma opioid receptor type 1 sites in guinea pig brain membranes at 0.1 uM of BNITMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
George Washington University Medical Center

Curated by ChEMBL
LigandPNGBDBM50035131((+)-(6R,11S)-6,11-dimethyl-3-(3-methyl-but-2-enyl)...)
Affinity DataKd:  11.6nMAssay Description:Binding constant (Kd) for [3H]-DTG binding to Sigma opioid receptor type 1 of guinea pig brain membranes at 200 nM concentration of the compoundMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
George Washington University Medical Center

Curated by ChEMBL
LigandPNGBDBM81982(CAS_97-39-2 | DITOLYLGUANIDINE | DTG | Di-o-tolylg...)
Affinity DataKd:  13.6nMAssay Description:Binding constant (Kd) for [3H]DTG binding to Sigma opioid receptor type 1 of guinea pig brain membranes at 1 uM BNITMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
George Washington University Medical Center

Curated by ChEMBL
LigandPNGBDBM81982(CAS_97-39-2 | DITOLYLGUANIDINE | DTG | Di-o-tolylg...)
Affinity DataKd:  11.6nMAssay Description:Binding constant (Kd) for [3H]DTG binding to Sigma opioid receptor type 1 of guinea pig brain membranes at 5 uM BNITMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
George Washington University Medical Center

Curated by ChEMBL
LigandPNGBDBM50445185(CHEMBL3103203)
Affinity DataKd:  7.20nMAssay Description:Displacement of [125I]N-IAC44 from sigma 1 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
George Washington University Medical Center

Curated by ChEMBL
LigandPNGBDBM50445186(CHEMBL3103202)
Affinity DataKd:  11nMAssay Description:Displacement of [125I]N-IACoc from sigma 1 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50423875((+)-[3H]-Pentazocine | CHEMBL2311194 | [3H]-(+)-Pe...)
Affinity DataKd:  2.90nMAssay Description:Binding affinity to guinea pig brain sigma1 receptorMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
Institut F£R Pharmazeutische Und Medizinische Chemie Der Universit£T M£Nster

Curated by ChEMBL
LigandPNGBDBM50032403((Pentazocine) 6,11-Dimethyl-3-(3-methyl-but-2-enyl...)
Affinity DataKd:  2.90nMAssay Description:Binding affinity to sigma1 receptor in Hartley guinea pig brain cortex membranes incubated for 150 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
George Washington University Medical Center

Curated by ChEMBL
LigandPNGBDBM50543315(CHEMBL4642064)
Affinity DataKd: >1.00E+3nMAssay Description:Displacement of [3H](+)-pentazocine from recombinant sigma 1 receptor (unknown origin) expressed in baculovirus infected Sf9 cell membranes after 1.5...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
George Washington University Medical Center

Curated by ChEMBL
LigandPNGBDBM50543316(CHEMBL4640674)
Affinity DataKd: >1.00E+3nMAssay Description:Displacement of [3H](+)-pentazocine from recombinant sigma 1 receptor (unknown origin) expressed in baculovirus infected Sf9 cell membranes after 1.5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
George Washington University Medical Center

Curated by ChEMBL
LigandPNGBDBM50543317(CHEMBL4638486)
Affinity DataKd: >1.00E+3nMAssay Description:Displacement of [3H](+)-pentazocine from recombinant sigma 1 receptor (unknown origin) expressed in baculovirus infected Sf9 cell membranes after 1.5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
George Washington University Medical Center

Curated by ChEMBL
LigandPNGBDBM50543318(CHEMBL4644063)
Affinity DataKd: >1.00E+3nMAssay Description:Displacement of [3H](+)-pentazocine from recombinant sigma 1 receptor (unknown origin) expressed in baculovirus infected Sf9 cell membranes after 1.5...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
George Washington University Medical Center

Curated by ChEMBL
LigandPNGBDBM50543319(CHEMBL4639260)
Affinity DataKd: >1.00E+3nMAssay Description:Displacement of [3H](+)-pentazocine from recombinant sigma 1 receptor (unknown origin) expressed in baculovirus infected Sf9 cell membranes after 1.5...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(RAT)
Washington University

Curated by ChEMBL
LigandPNGBDBM8903((1S,2R,10S,11S,14S,15S)-14-acetyl-2,15-dimethyltet...)
Affinity DataKd:  239nMAssay Description:Displacement of [3H]pentazocine from sigma-1 opioid receptor in rat liver membranes after 1 hr by liquid scintillation spectrometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed