Compile Data Set for Download or QSAR
maximum 50k data
Found 47 of kd data for polymerid = 4993
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Universitá

LigandPNGBDBM50241990(CHEMBL502489 | Camboginol | Garcinol | Garcinol, 1)
Affinity DataKd:  400nMT: 2°CAssay Description:The p300 activity assays were performed by a colorimetric kit (JM-K322-100, MBL) using active recombinant p300/HAT as positive control and acetyl-CoA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Universitá

LigandPNGBDBM50603097(CHEMBL5195288)
Affinity DataKd:  2.51E+3nMAssay Description:Binding affinity to EP300 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Universitá

LigandPNGBDBM84874(Guttiferone A, 3)
Affinity DataKd:  100nMT: 2°CAssay Description:The p300 activity assays were performed by a colorimetric kit (JM-K322-100, MBL) using active recombinant p300/HAT as positive control and acetyl-CoA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Universitá

LigandPNGBDBM84875(Guttiferone E, 4)
Affinity DataKd:  390nMT: 2°CAssay Description:The p300 activity assays were performed by a colorimetric kit (JM-K322-100, MBL) using active recombinant p300/HAT as positive control and acetyl-CoA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Universitá

LigandPNGBDBM84877(Clusianone, 10)
Affinity DataKd:  810nMT: 2°CAssay Description:The p300 activity assays were performed by a colorimetric kit (JM-K322-100, MBL) using active recombinant p300/HAT as positive control and acetyl-CoA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Universitá

LigandPNGBDBM50081171(CHEMBL3421905)
Affinity DataKd:  2.40E+3nMAssay Description:Binding affinity to human recombinant P300 catalytic domain by SPR analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Universitá

LigandPNGBDBM50081172(CHEMBL3421930)
Affinity DataKd:  110nMAssay Description:Binding affinity to human recombinant P300 catalytic domain by SPR analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Universitá

LigandPNGBDBM188519(SGC-CBP30)
Affinity DataKd:  32nMAssay Description:Binding affinity to human p300 by ITC analysisMore data for this Ligand-Target Pair
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Universitá

LigandPNGBDBM50151663(CHEMBL3774655)
Affinity DataKd:  167nMAssay Description:Inhibition of human p300 expressed in competent escherichia coli BL21(DE3)-R3-pRARE2 cells by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Universitá

LigandPNGBDBM50396040(CHEMBL1823895)
Affinity DataKd:  345nMAssay Description:Binding affinity to recombinant P300 CH1 domain assessed as dissociation constant by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Universitá

LigandPNGBDBM50241990(CHEMBL502489 | Camboginol | Garcinol | Garcinol, 1)
Affinity DataKd:  1.80E+3nMAssay Description:Binding affinity to HAT p300 catalytic domain by fluorometric titrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Universitá

LigandPNGBDBM50265449((1R,3S,9S,11R)-7-(3-Hydroxy-4-methoxy-benzoyl)-4,4...)
Affinity DataKd:  1.40E+3nMAssay Description:Binding affinity to HAT p300 catalytic domain by fluorometric titrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Universitá

LigandPNGBDBM50377962(CAMBOGIN)
Affinity DataKd:  1.10E+3nMAssay Description:Binding affinity to HAT p300 catalytic domain by fluorometric titrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Universitá

LigandPNGBDBM50241990(CHEMBL502489 | Camboginol | Garcinol | Garcinol, 1)
Affinity DataKd:  6.60E+3nMAssay Description:Binding affinity to HAT p300 catalytic domain by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Universitá

LigandPNGBDBM50265449((1R,3S,9S,11R)-7-(3-Hydroxy-4-methoxy-benzoyl)-4,4...)
Affinity DataKd:  9.10E+3nMAssay Description:Binding affinity to HAT p300 catalytic domain by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Universitá

LigandPNGBDBM50377962(CAMBOGIN)
Affinity DataKd:  5.90E+3nMAssay Description:Binding affinity to HAT p300 catalytic domain by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Universitá

LigandPNGBDBM220447(US10633379, Compound X | US9296741, 36)
Affinity DataKd:  87nMAssay Description:Binding affinity to human EP300 (A1040 to G1161 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Universitá

LigandPNGBDBM50366670(CHEMBL4173488)
Affinity DataKd:  110nMAssay Description:Binding affinity to human EP300 (A1040 to G1161 residues) expressed in bacterial expression system by BROMOScan assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Universitá

LigandPNGBDBM50455480(CHEMBL4218735)
Affinity DataKd: <3.02E+4nMAssay Description:Binding affinity to human partial length DNA-tagged EP300 expressed in bacteria by BROMOscan methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Universitá

LigandPNGBDBM179481(US9675697, Cpd. No. 73)
Affinity DataKd:  550nMAssay Description:Binding affinity to human partial length EP300 (A1040 to G1161 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Universitá

LigandPNGBDBM50453949(CHEMBL4208820 | US11247989, Example 87)
Affinity DataKd:  0.120nMAssay Description:Binding affinity to human partial length EP300 (A1040 to G1161 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Universitá

LigandPNGBDBM50537291(CHEMBL4555191)
Affinity DataKd:  750nMAssay Description:Binding affinity to human GST-fused p300 CH1 domain (323 to 423 residues) under hypoxic condition by SPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Universitá

LigandPNGBDBM50524839(CHEMBL4466328)
Affinity DataKd:  530nMAssay Description:Binding affinity to p300 CH1 domain (unknown origin) by tryptophan fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Universitá

LigandPNGBDBM50537293(CHEMBL4590644)
Affinity DataKd:  6.74E+3nMAssay Description:Binding affinity to p300 (unknown origin) by fluorescence anisotrophyMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Universitá

LigandPNGBDBM50537294(CHEMBL4514946)
Affinity DataKd:  3.00E+4nMAssay Description:Binding affinity to p300 CH1 domain (unknown origin) by tryptophan fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Universitá

LigandPNGBDBM50537295(CHEMBL4524475)
Affinity DataKd:  690nMAssay Description:Binding affinity to p300 CH1 domain (unknown origin) by fluorescence anisotropy competition assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Universitá

LigandPNGBDBM50524834(CHEMBL4435255)
Affinity DataKd:  690nMAssay Description:Binding affinity to p300 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Universitá

LigandPNGBDBM50524839(CHEMBL4466328)
Affinity DataKd:  530nMAssay Description:Binding affinity to p300-CH1 domain (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Universitá

LigandPNGBDBM50537297(CHEMBL4542925)
Affinity DataKd:  3.62E+3nMAssay Description:Binding affinity to human GST-fused p300 CH1 domain (323 to 423 residues) under hypoxic condition by SPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Universitá

LigandPNGBDBM50537301(CHEMBL4593074)
Affinity DataKd:  45nMAssay Description:Binding affinity to p300 (unknown origin) by ITC assayMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Universitá

LigandPNGBDBM50537301(CHEMBL4593074)
Affinity DataKd:  16nMAssay Description:Binding affinity to p300 (unknown origin) by fluorescence anisotrophyMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Universitá

LigandPNGBDBM249277(US10017501, Compound 1020-18 | US9458145, 1020-18)
Affinity DataKd:  220nMAssay Description:Binding affinity to human partial length EP300 (A1040 to G1161 residues) expressed in bacterial expression system after 1 hr by bromoscan assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Universitá

LigandPNGBDBM50539801(CHEMBL4648912 | US11840533, Compound 70)
Affinity DataKd:  37nMAssay Description:Binding affinity to human partial length EP300 (A1040 to G1161 residues) expressed in bacterial expression system by BROMOscan assayMore data for this Ligand-Target Pair
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Universitá

LigandPNGBDBM188519(SGC-CBP30)
Affinity DataKd:  3.18E+7nMAssay Description:Inhibition of human BRD4 BD1 (67 to 152 residues) preincubated for 15 mins followed by addition of C-terminal biotinylated synthetic K5,8,12,16 tetra...More data for this Ligand-Target Pair
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Universitá

LigandPNGBDBM50559467(CHEMBL4763016)
Affinity DataKd:  1.20E+3nMAssay Description:Binding affinity to human partial length EP300 (A1040 to G1161 residues) expressed in bacterial expression system by BROMOscan methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Universitá

LigandPNGBDBM50365463(CHEMBL1232461)
Affinity DataKd:  7.10E+4nMAssay Description:Binding affinity to human partial length EP300 (A1040 to G1161 residues) expressed in bacterial expression system by BROMOscan methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Universitá

LigandPNGBDBM50467836(CHEMBL4282264)
Affinity DataKd:  0.00128nMAssay Description:Binding affinity to human Biotin-Avi-P300 assessed as dissociation constant using Neutravidin as ligand measured by Surface Plasmon Resonance methodMore data for this Ligand-Target Pair
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Universitá

LigandPNGBDBM50467836(CHEMBL4282264)
Affinity DataKd:  1.40nMAssay Description:Binding affinity to human Biotin-Avi-P300 using Neutravidin as ligand measured by Surface Plasmon Resonance methodMore data for this Ligand-Target Pair
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Universitá

LigandPNGBDBM50159140(CHEMBL3785648)
Affinity DataKd:  2.26E+4nMAssay Description:Binding affinity to human His-Tev tagged EP300 expressed in bacterial expression system incubated for 30 mins by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Universitá

LigandPNGBDBM50559314(CHEMBL4741587)
Affinity DataKd:  470nMAssay Description:Binding affinity to human His-Tev tagged EP300 expressed in bacterial expression system incubated for 30 mins by isothermal titration calorimetryMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Universitá

LigandPNGBDBM50571550(CHEMBL4867046)
Affinity DataKd:  285nMAssay Description:Binding affinity to human partial length EP300 (A1040 to G1161 residues) expressed in bacterial expression system by BromoELECT assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Universitá

LigandPNGBDBM50571557(CHEMBL4853072)
Affinity DataKd:  215nMAssay Description:Binding affinity to human partial length EP300 (A1040 to G1161 residues) expressed in bacterial expression system by BromoELECT assayMore data for this Ligand-Target Pair
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Universitá

LigandPNGBDBM50571569(CHEMBL4875989)
Affinity DataKd:  1.30E+4nMAssay Description:Binding affinity to human partial length EP300 (A1040 to G1161 residues) expressed in bacterial expression system by BromoELECT assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Universitá

LigandPNGBDBM50579718(CHEMBL5083683)
Affinity DataKd: <250nMAssay Description:Binding affinity to human EP300 assessed as dissociation constant by BROMOscan assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Universitá

LigandPNGBDBM50579715(CHEMBL5089448)
Affinity DataKd:  240nMAssay Description:Binding affinity to human EP300 assessed as dissociation constant by BROMOscan assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Universitá

LigandPNGBDBM50584925(CHEMBL5079885)
Affinity DataKd: <3.16E+3nMAssay Description:Binding affinity to human EP300 bromodomain assessed as dissociation constant by BROMOscan methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Universitá

LigandPNGBDBM84873(Nemorosone, 2)
Affinity DataKd:  250nMT: 2°CAssay Description:The p300 activity assays were performed by a colorimetric kit (JM-K322-100, MBL) using active recombinant p300/HAT as positive control and acetyl-CoA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed