Compile Data Set for Download or QSAR
maximum 50k data
Found 30 of kd data for polymerid = 50000332
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM50060993(4'-FLUORO-1,1'-BIPHENYL-4-CARBOXYLIC ACID | 4'-Flu...)
Affinity DataKd:  4.00E+5nMAssay Description:Binding affinity to BH3 binding groove of BclXLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM50270877((R)-4-(4-((2-(4-chlorophenyl)-5,5-dimethylcyclohex...)
Affinity DataKd:  55nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan™ platform: T7 phage strains displaying BCL2 proteins were grown ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM552906(2-(1H-Pyrrolo[2,3-b]pyridin-5-yl-oxy)-4-(4-((2-(3-...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan™ platform: T7 phage strains displaying BCL2 proteins were grown ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM552907(2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)-4-(4-((4,4-di...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan™ platform: T7 phage strains displaying BCL2 proteins were grown ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM552908(2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)-4-(4-((2-(3-f...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan™ platform: T7 phage strains displaying BCL2 proteins were grown ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM552909(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-N-((4-(((7-...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan™ platform: T7 phage strains displaying BCL2 proteins were grown ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM552910(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4,4-...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan™ platform: T7 phage strains displaying BCL2 proteins were grown ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM552911(2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)-4-(4-((4,4-di...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan™ platform: T7 phage strains displaying BCL2 proteins were grown ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM552912(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4,4-...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan™ platform: T7 phage strains displaying BCL2 proteins were grown ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM552913(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4,4-...)
Affinity DataKd:  55nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan™ platform: T7 phage strains displaying BCL2 proteins were grown ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM552914(2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)-4-(4-((4,4-di...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan™ platform: T7 phage strains displaying BCL2 proteins were grown ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM555311(2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)-4-(4-((2-(3-e...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan™ platform: T7 phage strains displaying BCL2 proteins were grown ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM555312(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((2-(3...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan™ platform: T7 phage strains displaying BCL2 proteins were grown ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM555313(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((2-(3...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan™ platform: T7 phage strains displaying BCL2 proteins were grown ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM555314(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((2-(3...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan™ platform: T7 phage strains displaying BCL2 proteins were grown ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM555315(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4,4-...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan™ platform: T7 phage strains displaying BCL2 proteins were grown ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM555316(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4,4-...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan™ platform: T7 phage strains displaying BCL2 proteins were grown ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM555317(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4,4-...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan™ platform: T7 phage strains displaying BCL2 proteins were grown ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM555318(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4,4-...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan™ platform: T7 phage strains displaying BCL2 proteins were grown ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM552923(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((2-(3...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan™ platform: T7 phage strains displaying BCL2 proteins were grown ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM555320(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((2-(3...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan™ platform: T7 phage strains displaying BCL2 proteins were grown ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM552925(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((2-(3...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan™ platform: T7 phage strains displaying BCL2 proteins were grown ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM552926(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((2-(3...)
Affinity DataKd:  55nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan™ platform: T7 phage strains displaying BCL2 proteins were grown ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM552927(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((2-(3...)
Affinity DataKd:  55nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan™ platform: T7 phage strains displaying BCL2 proteins were grown ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM555324(2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((2-(3...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan™ platform: T7 phage strains displaying BCL2 proteins were grown ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM552929(2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)-4-(4-((2-(3-(...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan™ platform: T7 phage strains displaying BCL2 proteins were grown ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM552930((R)-4-(4-((5,5-Dimethyl-2-(3-methylbicyclo[1.1.1]p...)
Affinity DataKd:  55nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan™ platform: T7 phage strains displaying BCL2 proteins were grown ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM552931((R)-4-(4-((5,5-dimethyl-2-(3-methylbicyclo[1.1.1]p...)
Affinity DataKd:  55nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan™ platform: T7 phage strains displaying BCL2 proteins were grown ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM60828(ABT-199 | BDBM189459 | US10213433, Compound 5 | US...)
Affinity DataKd:  55nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan™ platform: T7 phage strains displaying BCL2 proteins were grown ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBcl2-associated agonist of cell death(Homo sapiens (Human))
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM50270875(5,6,7,8-tetrahydro-1-naphthol | CHEMBL449132)
Affinity DataKd:  2.00E+6nMAssay Description:Binding affinity to BH3 binding groove of BclXLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed