Compile Data Set for Download or QSAR
Report error Found 80 of kd data for polymerid = 50000450
Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590927BDBM50590927(Apilimod | Sta-5326 | STA 5326 | STA-5326 | APILIM...)
Affinity DataKd:  0.0750nMAssay Description:Binding affinity to human wild type partial length PIKFYVE (F1512 to C2098 residues) mammalian expression assessed as dissociation constant by Kinome...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50641404BDBM50641404(CHEMBL5572490)
Affinity DataKd:  0.470nMAssay Description:Binding affinity to PIKfyve (unknown origin) assessed as dissociation constant incubated for 1 hr by qPCR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50635837BDBM50635837(CHEMBL5555919)
Affinity DataKd:  0.910nMAssay Description:Binding affinity to N-terminal His-tagged human PIKfyve expressed in Sf9 cells assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 597632BDBM597632(US11603372, Example 7 | 4-morpholino-2-[(2E)-2-(m-...)
Affinity DataKd: <1nMAssay Description:For most assays, kinase-tagged T7 phage strains were prepared in an E. colihost derived from the BL21 strain. E. coli were grown to log-phase and inf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 597630BDBM597630(US11603372, Example 4 | 4-morpholino-2-[(2E)-2-(m-...)
Affinity DataKd: <1nMAssay Description:For most assays, kinase-tagged T7 phage strains were prepared in an E. colihost derived from the BL21 strain. E. coli were grown to log-phase and inf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 645754BDBM645754(US20240018151, Example 11)
Affinity DataKd: <1nMAssay Description:Kinase-tagged T7 phage strains are prepared in an E. coli host derived from the BL21 strain. E. coli are grown to log-phase and infected with T7 phag...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2024
Entry Details
US Patent

Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 597636BDBM597636(US11603372, Example 12 | 4-morpholino-N-[(E)-m-tol...)
Affinity DataKd: <1nMAssay Description:For most assays, kinase-tagged T7 phage strains were prepared in an E. colihost derived from the BL21 strain. E. coli were grown to log-phase and inf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 597640BDBM597640(US11603372, Example 261 | 4-morpholino-N-[(E)-m- t...)
Affinity DataKd: <1nMAssay Description:For most assays, kinase-tagged T7 phage strains were prepared in an E. colihost derived from the BL21 strain. E. coli were grown to log-phase and inf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 645755BDBM645755(US20240018151, Example 14)
Affinity DataKd: <1nMAssay Description:Kinase-tagged T7 phage strains are prepared in an E. coli host derived from the BL21 strain. E. coli are grown to log-phase and infected with T7 phag...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2024
Entry Details
US Patent

Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 597628BDBM597628(US11603372, Example 2 | 4-morpholino-N-[(E)-m-toly...)
Affinity DataKd: <1nMAssay Description:For most assays, kinase-tagged T7 phage strains were prepared in an E. colihost derived from the BL21 strain. E. coli were grown to log-phase and inf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 597643BDBM597643(US11603372, Example 264 | 6-(3,5-dimethylisoxazol-...)
Affinity DataKd: <1nMAssay Description:For most assays, kinase-tagged T7 phage strains were prepared in an E. colihost derived from the BL21 strain. E. coli were grown to log-phase and inf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 597642BDBM597642(US11603372, Example 263 | 6-(3,5-dimethyl-1H-pyraz...)
Affinity DataKd: <1nMAssay Description:For most assays, kinase-tagged T7 phage strains were prepared in an E. colihost derived from the BL21 strain. E. coli were grown to log-phase and inf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 597641BDBM597641(US11603372, Example 262 | 6-(1-methylpyrazol-4-yl)...)
Affinity DataKd: <1nMAssay Description:For most assays, kinase-tagged T7 phage strains were prepared in an E. colihost derived from the BL21 strain. E. coli were grown to log-phase and inf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50641403BDBM50641403(CHEMBL5568998)
Affinity DataKd:  1.70nMAssay Description:Binding affinity to PIKfyve (unknown origin) assessed as dissociation constant incubated for 1 hr by qPCR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 645763BDBM645763(US20240018151, Example 28)
Affinity DataKd:  3nMAssay Description:Kinase-tagged T7 phage strains are prepared in an E. coli host derived from the BL21 strain. E. coli are grown to log-phase and infected with T7 phag...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2024
Entry Details
US Patent

Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 645761BDBM645761(US20240018151, Example 24)
Affinity DataKd:  3nMAssay Description:Kinase-tagged T7 phage strains are prepared in an E. coli host derived from the BL21 strain. E. coli are grown to log-phase and infected with T7 phag...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2024
Entry Details
US Patent

Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 645749BDBM645749(US20240018151, Example 15 | US20240018151, Example...)
Affinity DataKd:  3nMAssay Description:Kinase-tagged T7 phage strains are prepared in an E. coli host derived from the BL21 strain. E. coli are grown to log-phase and infected with T7 phag...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2024
Entry Details
US Patent

Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50635836BDBM50635836(CHEMBL2032358)
Affinity DataKd:  3.80nMAssay Description:Binding affinity to PIKfyve (unknown origin) assessed as dissociation constant incubated for 1 hr by qPCR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50635836BDBM50635836(CHEMBL2032358)
Affinity DataKd:  5.30nMAssay Description:Binding affinity to PIKfyve (unknown origin) assessed as dissociation constant by KINOMEscan profiling methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 597631BDBM597631(US11603372, Example 5 | 4-morpholino-2-[(2E)-2-(m-...)
Affinity DataKd:  5.5nMAssay Description:For most assays, kinase-tagged T7 phage strains were prepared in an E. colihost derived from the BL21 strain. E. coli were grown to log-phase and inf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 597629BDBM597629(US11603372, Example 3 | 4-morpholino-N-[(E)-m-toly...)
Affinity DataKd:  5.5nMAssay Description:For most assays, kinase-tagged T7 phage strains were prepared in an E. colihost derived from the BL21 strain. E. coli were grown to log-phase and inf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 597645BDBM597645(US11603372, Example 268 | 6-(3,5-dimethyl-1H-pyraz...)
Affinity DataKd:  5.5nMAssay Description:For most assays, kinase-tagged T7 phage strains were prepared in an E. colihost derived from the BL21 strain. E. coli were grown to log-phase and inf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 597635BDBM597635(US11603372, Example 11 | 4-morpholino-N-[(E)-m-tol...)
Affinity DataKd:  5.5nMAssay Description:For most assays, kinase-tagged T7 phage strains were prepared in an E. colihost derived from the BL21 strain. E. coli were grown to log-phase and inf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 597633BDBM597633(US11603372, Example 9 | 4-Morpholino-N-[(E)-m-toly...)
Affinity DataKd:  5.5nMAssay Description:For most assays, kinase-tagged T7 phage strains were prepared in an E. colihost derived from the BL21 strain. E. coli were grown to log-phase and inf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 597638BDBM597638(US11603372, Example 22 | N-(azetidin-3-yl)-4-morph...)
Affinity DataKd:  5.5nMAssay Description:For most assays, kinase-tagged T7 phage strains were prepared in an E. colihost derived from the BL21 strain. E. coli were grown to log-phase and inf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 597644BDBM597644(US11603372, Example 267 | 6-(3,5-dimethylisoxazol-...)
Affinity DataKd:  5.5nMAssay Description:For most assays, kinase-tagged T7 phage strains were prepared in an E. colihost derived from the BL21 strain. E. coli were grown to log-phase and inf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 597627BDBM597627(US11603372, Example 1)
Affinity DataKd:  5.5nMAssay Description:For most assays, kinase-tagged T7 phage strains were prepared in an E. colihost derived from the BL21 strain. E. coli were grown to log-phase and inf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 557265BDBM557265(US11352354, Example V-c-17)
Affinity DataKd:  6.40nMAssay Description:Binding affinity to N-terminal His-tagged human PIKfyve expressed in Sf9 cells assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 557265BDBM557265(US11352354, Example V-c-17)
Affinity DataKd:  6.40nMAssay Description:Binding affinity to PIKFYVE (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 645749BDBM645749(US20240018151, Example 15 | US20240018151, Example...)
Affinity DataKd:  7.5nMAssay Description:Kinase-tagged T7 phage strains are prepared in an E. coli host derived from the BL21 strain. E. coli are grown to log-phase and infected with T7 phag...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2024
Entry Details
US Patent

Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 645744BDBM645744(US20240018151, Example 17 | US20240018151, Example...)
Affinity DataKd:  7.5nMAssay Description:Kinase-tagged T7 phage strains are prepared in an E. coli host derived from the BL21 strain. E. coli are grown to log-phase and infected with T7 phag...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2024
Entry Details
US Patent

Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 645759BDBM645759(US20240018151, Example 19)
Affinity DataKd:  7.5nMAssay Description:Kinase-tagged T7 phage strains are prepared in an E. coli host derived from the BL21 strain. E. coli are grown to log-phase and infected with T7 phag...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2024
Entry Details
US Patent

Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 645760BDBM645760(US20240018151, Example 20)
Affinity DataKd:  7.5nMAssay Description:Kinase-tagged T7 phage strains are prepared in an E. coli host derived from the BL21 strain. E. coli are grown to log-phase and infected with T7 phag...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2024
Entry Details
US Patent

Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 645762BDBM645762(US20240018151, Example 25)
Affinity DataKd:  7.5nMAssay Description:Kinase-tagged T7 phage strains are prepared in an E. coli host derived from the BL21 strain. E. coli are grown to log-phase and infected with T7 phag...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2024
Entry Details
US Patent

Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 645744BDBM645744(US20240018151, Example 17 | US20240018151, Example...)
Affinity DataKd:  7.5nMAssay Description:Kinase-tagged T7 phage strains are prepared in an E. coli host derived from the BL21 strain. E. coli are grown to log-phase and infected with T7 phag...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2024
Entry Details
US Patent

Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 645758BDBM645758(US20240018151, Example 18)
Affinity DataKd:  7.5nMAssay Description:Kinase-tagged T7 phage strains are prepared in an E. coli host derived from the BL21 strain. E. coli are grown to log-phase and infected with T7 phag...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2024
Entry Details
US Patent

Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50595937BDBM50595937(CHEMBL5194705)
Affinity DataKd:  32nMAssay Description:Binding affinity to N-terminal His-tagged human PIKfyve expressed in Sf9 cells assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 597634BDBM597634(US11603372, Example 10 | 4-morpholino-N-[(E)-m-tol...)
Affinity DataKd:  35nMAssay Description:For most assays, kinase-tagged T7 phage strains were prepared in an E. colihost derived from the BL21 strain. E. coli were grown to log-phase and inf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 597639BDBM597639(US11603372, Example 255 | 4-morpholino-N-[2-(m- to...)
Affinity DataKd:  35nMAssay Description:For most assays, kinase-tagged T7 phage strains were prepared in an E. colihost derived from the BL21 strain. E. coli were grown to log-phase and inf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 597637BDBM597637(US11603372, Example 14 | N-[(E)-(3-chlorophenyl)me...)
Affinity DataKd:  35nMAssay Description:For most assays, kinase-tagged T7 phage strains were prepared in an E. colihost derived from the BL21 strain. E. coli were grown to log-phase and inf...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2023
Entry Details
US Patent

Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590927BDBM50590927(Apilimod | Sta-5326 | STA 5326 | STA-5326 | APILIM...)
Affinity DataKd:  75nMAssay Description:Binding affinity to recombinant PIKfyve (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50641405BDBM50641405(CHEMBL4126314)
Affinity DataKd:  115nMAssay Description:Binding affinity to PIKfyve (unknown origin) assessed as dissociation constant incubated for 1 hr by qPCR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50617126BDBM50617126(CHEMBL5413843)
Affinity DataKd:  270nMAssay Description:Binding affinity to wild type partial length human PIKFYVE (F1512 to C2098 residues) expressed in mammalian expression system by KdELECT kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50509365BDBM50509365(CHEMBL4564337)
Affinity DataKd:  1.00E+3nMAssay Description:Binding affinity to wild-type human partial length PIKFYVE (F1512 to C2098 residues) expressed in mammalian expression system by active-site directed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50617125BDBM50617125(CHEMBL5398852)
Affinity DataKd:  5.00E+3nMAssay Description:Binding affinity to wild type partial length human PIKFYVE (F1512 to C2098 residues) expressed in mammalian expression system by KdELECT kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 557266BDBM557266(US11352354, Example V-c-18)
Affinity DataKd:  6.40E+3nMAssay Description:1. Preparation of magnetic beads: biotin-labeled small molecule ligand and avidin-coated magnetic beads were allowed to interact at room temperature ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2022
Entry Details
US Patent

Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 557287BDBM557287(US11352354, Example V-c-8)
Affinity DataKd:  1.30E+4nMAssay Description:1. Preparation of magnetic beads: biotin-labeled small molecule ligand and avidin-coated magnetic beads were allowed to interact at room temperature ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2022
Entry Details
US Patent

Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 557267BDBM557267(US11352354, Example V-c-19)
Affinity DataKd:  1.50E+4nMAssay Description:1. Preparation of magnetic beads: biotin-labeled small molecule ligand and avidin-coated magnetic beads were allowed to interact at room temperature ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2022
Entry Details
US Patent

Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 557261BDBM557261(US11352354, Example V-c-13)
Affinity DataKd:  1.60E+4nMAssay Description:1. Preparation of magnetic beads: biotin-labeled small molecule ligand and avidin-coated magnetic beads were allowed to interact at room temperature ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2022
Entry Details
US Patent

Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 557267BDBM557267(US11352354, Example V-c-19)
Affinity DataKd:  1.60E+4nMAssay Description:1. Preparation of magnetic beads: biotin-labeled small molecule ligand and avidin-coated magnetic beads were allowed to interact at room temperature ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2022
Entry Details
US Patent

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