Compile Data Set for Download or QSAR
maximum 50k data
Found 32 of kd data for polymerid = 50006167,50006362,50006490,50006781,50007060,50007089,5291,5691,8232
TargetLysine-specific demethylase 6A(Homo sapiens (Human))
University Of Oxford

LigandPNGBDBM231631(Biotin-KAPRKQLATKAARKMe3SAPATGG | H3K27Me3 peptide)
Affinity DataKd:  2.00E+3nMpH: 7.5 T: 2°CAssay Description:Binding assays were carried out as 20-μl reactions in 384-well white ProxiPlates (Perkin-Elmer Life Sciences) as described [Hong et al., Proc. N...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50606687(CHEMBL5220246)
Affinity DataKd:  3.90E+3nMAssay Description:Binding affinity to recombinant full length N-terminal hexahistidine-tagged human FTO expressed in Escherichia coli BL21 by competition-based NMR bin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
The University Of Texas M.D. Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM50245000(CHEMBL4096760)
Affinity DataKd:  60nMAssay Description:Binding affinity to ARID/PHD1/Zn binding domain truncated human N-terminal His-SUMO-tagged KDM5A (1 to 588 residues) expressed in Escherichia coli by...More data for this Ligand-Target Pair
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
The University Of Texas M.D. Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM50245001(CHEMBL4059617)
Affinity DataKd:  470nMAssay Description:Binding affinity to ARID/PHD1/Zn binding domain truncated human N-terminal His-SUMO-tagged KDM5A (1 to 588 residues) expressed in Escherichia coli by...More data for this Ligand-Target Pair
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
The University Of Texas M.D. Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM50245002(CHEMBL4081571)
Affinity DataKd:  150nMAssay Description:Binding affinity at [3H]QNB and GppNHp radiolabeled muscarinic M2 receptor in rat heart.More data for this Ligand-Target Pair
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
The University Of Texas M.D. Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM50245003(CHEMBL4066179)
Affinity DataKd:  250nMAssay Description:Binding affinity to ARID/PHD1/Zn binding domain truncated human N-terminal His-SUMO-tagged KDM5A (1 to 588 residues) expressed in Escherichia coli by...More data for this Ligand-Target Pair
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
The University Of Texas M.D. Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM281089(US10022354, Example 29)
Affinity DataKd:  2.40E+3nMAssay Description:Binding affinity to ARID/PHD1/Zn binding domain truncated human N-terminal His-SUMO-tagged KDM5A (1 to 588 residues) expressed in Escherichia coli by...More data for this Ligand-Target Pair
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
The University Of Texas M.D. Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM281088(US10022354, Example 28)
Affinity DataKd: >1.20E+4nMAssay Description:Binding affinity to ARID/PHD1/Zn binding domain truncated human N-terminal His-SUMO-tagged KDM5A (1 to 588 residues) expressed in Escherichia coli by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
The University Of Texas M.D. Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM320423(2-[(2-chlorophenyl)-propoxy- methyl]-1H-pyrrolo[3,...)
Affinity DataKd:  530nMAssay Description:Binding affinity to ARID/PHD1/Zn binding domain truncated human N-terminal His-SUMO-tagged KDM5A (1 to 588 residues) expressed in Escherichia coli by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
The University Of Texas M.D. Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM50245037(CHEMBL4062359)
Affinity DataKd:  220nMAssay Description:Binding affinity at [3H]QNB radiolabeled muscarinic M2 receptor in rat heart.More data for this Ligand-Target Pair
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
The University Of Texas M.D. Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM50245005(CHEMBL4070992)
Affinity DataKd:  210nMAssay Description:Binding affinity to ARID/PHD1/Zn binding domain truncated human N-terminal His-SUMO-tagged KDM5A (1 to 588 residues) expressed in Escherichia coli by...More data for this Ligand-Target Pair
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
The University Of Texas M.D. Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM50245006(CHEMBL4077310)
Affinity DataKd:  410nMAssay Description:Binding affinity to ARID/PHD1/Zn binding domain truncated human N-terminal His-SUMO-tagged KDM5A (1 to 588 residues) expressed in Escherichia coli by...More data for this Ligand-Target Pair
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
The University Of Texas M.D. Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM223320(KDOAM-25)
Affinity DataKd:  2.70E+3nMAssay Description:Binding affinity to ARID/PHD1/Zn binding domain truncated human N-terminal His-SUMO-tagged KDM5A (1 to 588 residues) expressed in Escherichia coli by...More data for this Ligand-Target Pair
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
The University Of Texas M.D. Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM50245004(CHEMBL4090351)
Affinity DataKd:  180nMAssay Description:Binding affinity to ARID/PHD1/Zn binding domain truncated human N-terminal His-SUMO-tagged KDM5A (1 to 588 residues) expressed in Escherichia coli by...More data for this Ligand-Target Pair
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
The University Of Texas M.D. Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM50282115(CHEMBL4165111)
Affinity DataKd:  800nMAssay Description:Inhibition of JARID1A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
The University Of Texas M.D. Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM50282162(CHEMBL4173016)
Affinity DataKd:  800nMAssay Description:Inhibition of JARID1A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 4B(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50457513(CHEMBL4212908)
Affinity DataKd:  1.27E+5nMAssay Description:Binding affinity to 6His-tagged and human KDM4B tandem TUDOR domain (916 to 1030 residues) expressed in Escherichia coli BL21(DE3)-T1R by ITC methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAlpha-ketoglutarate-dependent dioxygenase alkB homolog 3(Homo sapiens (Human))
Indian Institute Of Technology Hyderabad

Curated by ChEMBL
LigandPNGBDBM50463170(CHEMBL4239759)
Affinity DataKd:  7.81E+3nMAssay Description:Binding affinity to recombinant human AlkBH3 incubated for 2 mins by isothermal titration calorimetric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
The University Of Texas M.D. Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM50468053(CHEMBL4294426)
Affinity DataKd:  9.00E+3nMAssay Description:Binding affinity to KDM5A ARID/PhD1 domain deletion mutant (1 to 588 residues) (unknown origin) by ITC assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
The University Of Texas M.D. Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM50245002(CHEMBL4081571)
Affinity DataKd:  150nMAssay Description:Binding affinity to KDM5A ARID/PhD1 domain deletion mutant (1 to 588 residues) (unknown origin) by ITC assayMore data for this Ligand-Target Pair
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
The University Of Texas M.D. Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM50468052(CHEMBL4283844)
Affinity DataKd:  6.00E+3nMAssay Description:Binding affinity to KDM5A ARID/PhD1 domain deletion mutant (1 to 588 residues) (unknown origin) by ITC assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
The University Of Texas M.D. Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM60875(3-((6-(4,5-Dihydro-1H-benzo[d]azepin-3(2H)-yl)-2-(...)
Affinity DataKd:  1.20E+4nMAssay Description:Binding affinity to KDM5A ARID/PhD1 domain deletion mutant (1 to 588 residues) (unknown origin) by ITC assayMore data for this Ligand-Target Pair
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
The University Of Texas M.D. Anderson Cancer Center

Curated by ChEMBL
LigandPNGBDBM50468054(CHEMBL4284220)
Affinity DataKd:  260nMAssay Description:Binding affinity to KDM5A ARID/PhD1 domain deletion mutant (1 to 588 residues) (unknown origin) by ITC assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetLysine-specific demethylase 4D(Homo sapiens (Human))
Nankai University

Curated by ChEMBL
LigandPNGBDBM50574750(CHEMBL4850758)
Affinity DataKd:  36nMAssay Description:Inhibition of human KDM4D expressed in Escherichia coli BL21 (DE3) assessed as equilibrium dissociation constant measured by isothermal titration cal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50596052(CHEMBL5196484)
Affinity DataKd:  28nMAssay Description:Binding affinity to FTO (unknown origin) assessed as dissociation constant at 180 uM by isothermal titration calorimetry assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProbable JmjC domain-containing histone demethylation protein 2C(Homo sapiens (Human))
Hangzhou Normal University

Curated by ChEMBL
LigandPNGBDBM50594963(CHEMBL5191875)
Affinity DataKd:  2.67E+4nMAssay Description:Binding affinity to CM7 sensor chip immobilized partial-length JMJD1C (2274 to 2498 residues) (unknown origin) expressed in Escherichia coli assessed...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetProbable JmjC domain-containing histone demethylation protein 2C(Homo sapiens (Human))
Hangzhou Normal University

Curated by ChEMBL
LigandPNGBDBM50594964(CHEMBL5193187)
Affinity DataKd:  2.70E+3nMAssay Description:Binding affinity to CM7 sensor chip immobilized partial-length JMJD1C (2274 to 2498 residues) (unknown origin) expressed in Escherichia coli assessed...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetProbable JmjC domain-containing histone demethylation protein 2C(Homo sapiens (Human))
Hangzhou Normal University

Curated by ChEMBL
LigandPNGBDBM50594965(CHEMBL5173150)
Affinity DataKd:  8.06E+3nMAssay Description:Binding affinity to CM7 sensor chip immobilized partial-length JMJD1C (2274 to 2498 residues) (unknown origin) expressed in Escherichia coli assessed...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50606679(CHEMBL5218636)
Affinity DataKd:  1.20E+3nMAssay Description:Binding affinity to recombinant full length N-terminal hexahistidine-tagged human FTO expressed in Escherichia coli BL21 by competition-based NMR bin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50606681(CHEMBL5219846)
Affinity DataKd:  340nMAssay Description:Binding affinity to recombinant full length N-terminal hexahistidine-tagged human FTO expressed in Escherichia coli BL21 by competition-based NMR bin...More data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50606686(CHEMBL5219336)
Affinity DataKd:  670nMAssay Description:Binding affinity to recombinant full length N-terminal hexahistidine-tagged human FTO expressed in Escherichia coli BL21 by competition-based NMR bin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50117830(CHEMBL3613953)
Affinity DataKd:  1.30E+4nMAssay Description:Binding affinity to FTO (unknown origin) (31 to 505 residues) expressed in Escherichia coli BL21 (DE3) by ITC methodMore data for this Ligand-Target Pair