Found 32 of kd data for polymerid = 50006167,50006362,50006490,50006781,50007060,50007089,5291,5691,8232
Affinity DataKd: 2.00E+3nMpH: 7.5 T: 2°CAssay Description:Binding assays were carried out as 20-μl reactions in 384-well white ProxiPlates (Perkin-Elmer Life Sciences) as described [Hong et al., Proc. N...More data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))
University Of Oxford
Curated by ChEMBL
University Of Oxford
Curated by ChEMBL
Affinity DataKd: 3.90E+3nMAssay Description:Binding affinity to recombinant full length N-terminal hexahistidine-tagged human FTO expressed in Escherichia coli BL21 by competition-based NMR bin...More data for this Ligand-Target Pair
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
The University Of Texas M.D. Anderson Cancer Center
Curated by ChEMBL
The University Of Texas M.D. Anderson Cancer Center
Curated by ChEMBL
Affinity DataKd: 60nMAssay Description:Binding affinity to ARID/PHD1/Zn binding domain truncated human N-terminal His-SUMO-tagged KDM5A (1 to 588 residues) expressed in Escherichia coli by...More data for this Ligand-Target Pair
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
The University Of Texas M.D. Anderson Cancer Center
Curated by ChEMBL
The University Of Texas M.D. Anderson Cancer Center
Curated by ChEMBL
Affinity DataKd: 470nMAssay Description:Binding affinity to ARID/PHD1/Zn binding domain truncated human N-terminal His-SUMO-tagged KDM5A (1 to 588 residues) expressed in Escherichia coli by...More data for this Ligand-Target Pair
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
The University Of Texas M.D. Anderson Cancer Center
Curated by ChEMBL
The University Of Texas M.D. Anderson Cancer Center
Curated by ChEMBL
Affinity DataKd: 150nMAssay Description:Binding affinity at [3H]QNB and GppNHp radiolabeled muscarinic M2 receptor in rat heart.More data for this Ligand-Target Pair
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
The University Of Texas M.D. Anderson Cancer Center
Curated by ChEMBL
The University Of Texas M.D. Anderson Cancer Center
Curated by ChEMBL
Affinity DataKd: 250nMAssay Description:Binding affinity to ARID/PHD1/Zn binding domain truncated human N-terminal His-SUMO-tagged KDM5A (1 to 588 residues) expressed in Escherichia coli by...More data for this Ligand-Target Pair
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
The University Of Texas M.D. Anderson Cancer Center
Curated by ChEMBL
The University Of Texas M.D. Anderson Cancer Center
Curated by ChEMBL
Affinity DataKd: 2.40E+3nMAssay Description:Binding affinity to ARID/PHD1/Zn binding domain truncated human N-terminal His-SUMO-tagged KDM5A (1 to 588 residues) expressed in Escherichia coli by...More data for this Ligand-Target Pair
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
The University Of Texas M.D. Anderson Cancer Center
Curated by ChEMBL
The University Of Texas M.D. Anderson Cancer Center
Curated by ChEMBL
Affinity DataKd: >1.20E+4nMAssay Description:Binding affinity to ARID/PHD1/Zn binding domain truncated human N-terminal His-SUMO-tagged KDM5A (1 to 588 residues) expressed in Escherichia coli by...More data for this Ligand-Target Pair
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
The University Of Texas M.D. Anderson Cancer Center
Curated by ChEMBL
The University Of Texas M.D. Anderson Cancer Center
Curated by ChEMBL
Affinity DataKd: 530nMAssay Description:Binding affinity to ARID/PHD1/Zn binding domain truncated human N-terminal His-SUMO-tagged KDM5A (1 to 588 residues) expressed in Escherichia coli by...More data for this Ligand-Target Pair
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
The University Of Texas M.D. Anderson Cancer Center
Curated by ChEMBL
The University Of Texas M.D. Anderson Cancer Center
Curated by ChEMBL
Affinity DataKd: 220nMAssay Description:Binding affinity at [3H]QNB radiolabeled muscarinic M2 receptor in rat heart.More data for this Ligand-Target Pair
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
The University Of Texas M.D. Anderson Cancer Center
Curated by ChEMBL
The University Of Texas M.D. Anderson Cancer Center
Curated by ChEMBL
Affinity DataKd: 210nMAssay Description:Binding affinity to ARID/PHD1/Zn binding domain truncated human N-terminal His-SUMO-tagged KDM5A (1 to 588 residues) expressed in Escherichia coli by...More data for this Ligand-Target Pair
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
The University Of Texas M.D. Anderson Cancer Center
Curated by ChEMBL
The University Of Texas M.D. Anderson Cancer Center
Curated by ChEMBL
Affinity DataKd: 410nMAssay Description:Binding affinity to ARID/PHD1/Zn binding domain truncated human N-terminal His-SUMO-tagged KDM5A (1 to 588 residues) expressed in Escherichia coli by...More data for this Ligand-Target Pair
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
The University Of Texas M.D. Anderson Cancer Center
Curated by ChEMBL
The University Of Texas M.D. Anderson Cancer Center
Curated by ChEMBL
Affinity DataKd: 2.70E+3nMAssay Description:Binding affinity to ARID/PHD1/Zn binding domain truncated human N-terminal His-SUMO-tagged KDM5A (1 to 588 residues) expressed in Escherichia coli by...More data for this Ligand-Target Pair
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
The University Of Texas M.D. Anderson Cancer Center
Curated by ChEMBL
The University Of Texas M.D. Anderson Cancer Center
Curated by ChEMBL
Affinity DataKd: 180nMAssay Description:Binding affinity to ARID/PHD1/Zn binding domain truncated human N-terminal His-SUMO-tagged KDM5A (1 to 588 residues) expressed in Escherichia coli by...More data for this Ligand-Target Pair
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
The University Of Texas M.D. Anderson Cancer Center
Curated by ChEMBL
The University Of Texas M.D. Anderson Cancer Center
Curated by ChEMBL
Affinity DataKd: 800nMAssay Description:Inhibition of JARID1A (unknown origin)More data for this Ligand-Target Pair
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
The University Of Texas M.D. Anderson Cancer Center
Curated by ChEMBL
The University Of Texas M.D. Anderson Cancer Center
Curated by ChEMBL
Affinity DataKd: 800nMAssay Description:Inhibition of JARID1A (unknown origin)More data for this Ligand-Target Pair
Affinity DataKd: 1.27E+5nMAssay Description:Binding affinity to 6His-tagged and human KDM4B tandem TUDOR domain (916 to 1030 residues) expressed in Escherichia coli BL21(DE3)-T1R by ITC methodMore data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase alkB homolog 3(Homo sapiens (Human))
Indian Institute Of Technology Hyderabad
Curated by ChEMBL
Indian Institute Of Technology Hyderabad
Curated by ChEMBL
Affinity DataKd: 7.81E+3nMAssay Description:Binding affinity to recombinant human AlkBH3 incubated for 2 mins by isothermal titration calorimetric methodMore data for this Ligand-Target Pair
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
The University Of Texas M.D. Anderson Cancer Center
Curated by ChEMBL
The University Of Texas M.D. Anderson Cancer Center
Curated by ChEMBL
Affinity DataKd: 9.00E+3nMAssay Description:Binding affinity to KDM5A ARID/PhD1 domain deletion mutant (1 to 588 residues) (unknown origin) by ITC assayMore data for this Ligand-Target Pair
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
The University Of Texas M.D. Anderson Cancer Center
Curated by ChEMBL
The University Of Texas M.D. Anderson Cancer Center
Curated by ChEMBL
Affinity DataKd: 150nMAssay Description:Binding affinity to KDM5A ARID/PhD1 domain deletion mutant (1 to 588 residues) (unknown origin) by ITC assayMore data for this Ligand-Target Pair
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
The University Of Texas M.D. Anderson Cancer Center
Curated by ChEMBL
The University Of Texas M.D. Anderson Cancer Center
Curated by ChEMBL
Affinity DataKd: 6.00E+3nMAssay Description:Binding affinity to KDM5A ARID/PhD1 domain deletion mutant (1 to 588 residues) (unknown origin) by ITC assayMore data for this Ligand-Target Pair
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
The University Of Texas M.D. Anderson Cancer Center
Curated by ChEMBL
The University Of Texas M.D. Anderson Cancer Center
Curated by ChEMBL
Affinity DataKd: 1.20E+4nMAssay Description:Binding affinity to KDM5A ARID/PhD1 domain deletion mutant (1 to 588 residues) (unknown origin) by ITC assayMore data for this Ligand-Target Pair
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
The University Of Texas M.D. Anderson Cancer Center
Curated by ChEMBL
The University Of Texas M.D. Anderson Cancer Center
Curated by ChEMBL
Affinity DataKd: 260nMAssay Description:Binding affinity to KDM5A ARID/PhD1 domain deletion mutant (1 to 588 residues) (unknown origin) by ITC assayMore data for this Ligand-Target Pair
Affinity DataKd: 36nMAssay Description:Inhibition of human KDM4D expressed in Escherichia coli BL21 (DE3) assessed as equilibrium dissociation constant measured by isothermal titration cal...More data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))
University Of Oxford
Curated by ChEMBL
University Of Oxford
Curated by ChEMBL
Affinity DataKd: 28nMAssay Description:Binding affinity to FTO (unknown origin) assessed as dissociation constant at 180 uM by isothermal titration calorimetry assayMore data for this Ligand-Target Pair
TargetProbable JmjC domain-containing histone demethylation protein 2C(Homo sapiens (Human))
Hangzhou Normal University
Curated by ChEMBL
Hangzhou Normal University
Curated by ChEMBL
Affinity DataKd: 2.67E+4nMAssay Description:Binding affinity to CM7 sensor chip immobilized partial-length JMJD1C (2274 to 2498 residues) (unknown origin) expressed in Escherichia coli assessed...More data for this Ligand-Target Pair
TargetProbable JmjC domain-containing histone demethylation protein 2C(Homo sapiens (Human))
Hangzhou Normal University
Curated by ChEMBL
Hangzhou Normal University
Curated by ChEMBL
Affinity DataKd: 2.70E+3nMAssay Description:Binding affinity to CM7 sensor chip immobilized partial-length JMJD1C (2274 to 2498 residues) (unknown origin) expressed in Escherichia coli assessed...More data for this Ligand-Target Pair
TargetProbable JmjC domain-containing histone demethylation protein 2C(Homo sapiens (Human))
Hangzhou Normal University
Curated by ChEMBL
Hangzhou Normal University
Curated by ChEMBL
Affinity DataKd: 8.06E+3nMAssay Description:Binding affinity to CM7 sensor chip immobilized partial-length JMJD1C (2274 to 2498 residues) (unknown origin) expressed in Escherichia coli assessed...More data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))
University Of Oxford
Curated by ChEMBL
University Of Oxford
Curated by ChEMBL
Affinity DataKd: 1.20E+3nMAssay Description:Binding affinity to recombinant full length N-terminal hexahistidine-tagged human FTO expressed in Escherichia coli BL21 by competition-based NMR bin...More data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))
University Of Oxford
Curated by ChEMBL
University Of Oxford
Curated by ChEMBL
Affinity DataKd: 340nMAssay Description:Binding affinity to recombinant full length N-terminal hexahistidine-tagged human FTO expressed in Escherichia coli BL21 by competition-based NMR bin...More data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))
University Of Oxford
Curated by ChEMBL
University Of Oxford
Curated by ChEMBL
Affinity DataKd: 670nMAssay Description:Binding affinity to recombinant full length N-terminal hexahistidine-tagged human FTO expressed in Escherichia coli BL21 by competition-based NMR bin...More data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))
University Of Oxford
Curated by ChEMBL
University Of Oxford
Curated by ChEMBL
Affinity DataKd: 1.30E+4nMAssay Description:Binding affinity to FTO (unknown origin) (31 to 505 residues) expressed in Escherichia coli BL21 (DE3) by ITC methodMore data for this Ligand-Target Pair