Compile Data Set for Download or QSAR
Report error Found 11 of kd data for polymerid = 50006362
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50596052BDBM50596052(CHEMBL5196484)
Affinity DataKd:  28nMAssay Description:Binding affinity to FTO (unknown origin) assessed as dissociation constant at 180 uM by isothermal titration calorimetry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50606681BDBM50606681(CHEMBL5219846)
Affinity DataKd:  340nMAssay Description:Binding affinity to recombinant full length N-terminal hexahistidine-tagged human FTO expressed in Escherichia coli BL21 by competition-based NMR bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50606686BDBM50606686(CHEMBL5219336)
Affinity DataKd:  670nMAssay Description:Binding affinity to recombinant full length N-terminal hexahistidine-tagged human FTO expressed in Escherichia coli BL21 by competition-based NMR bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50606679BDBM50606679(CHEMBL5218636)
Affinity DataKd:  1.20E+3nMAssay Description:Binding affinity to recombinant full length N-terminal hexahistidine-tagged human FTO expressed in Escherichia coli BL21 by competition-based NMR bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50325671BDBM50325671(CHEMBL8996 | eriodicryol | (S)-2-(3,4-dihydroxyphe...)
Affinity DataKd:  2.80E+3nMAssay Description:Binding affinity to GFP-tagged FTO (unknown origin) assessed as dissociation constant by microscale thermophoresis analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50325671BDBM50325671(CHEMBL8996 | eriodicryol | (S)-2-(3,4-dihydroxyphe...)
Affinity DataKd:  3.24E+3nMAssay Description:Binding affinity to GFP-tagged FTO (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50606687BDBM50606687(CHEMBL5220246)
Affinity DataKd:  3.90E+3nMAssay Description:Binding affinity to recombinant full length N-terminal hexahistidine-tagged human FTO expressed in Escherichia coli BL21 by competition-based NMR bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50117830BDBM50117830(CHEMBL3613953)
Affinity DataKd:  1.30E+4nMAssay Description:Binding affinity to FTO (unknown origin) (31 to 505 residues) expressed in Escherichia coli BL21 (DE3) by ITC methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 7461BDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | cid_5281...)
Affinity DataKd:  2.15E+4nMAssay Description:Binding affinity to GFP-tagged FTO (unknown origin) assessed as dissociation constant by microscale thermophoresis analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666115BDBM50666115(CHEMBL6177732)
Affinity DataKd:  2.76E+4nMAssay Description:Binding affinity to FTO (32 to 505 residues) (unknown origin) extracted from Escherichia coli BL21 (DE3) cells assessed as dissociation constant by I...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 15236BDBM15236(CHEMBL164 | Cannabiscetin | 3,5,7-trihydroxy-2-(3,...)
Affinity DataKd:  3.40E+4nMAssay Description:Binding affinity to GFP-tagged FTO (unknown origin) assessed as dissociation constant by microscale thermophoresis analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed