Compile Data Set for Download or QSAR
Report error Found 79 of kd data for polymerid = 5093,7404,50006601,50006642
TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50172100BDBM50172100(CHEMBL3809870)
Affinity DataKd:  0.400nMAssay Description:Binding affinity to BACE1 (unknown origin) by surface plasmon resonance spectroscopic analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2017
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50172102BDBM50172102(CHEMBL3809662)
Affinity DataKd:  0.600nMAssay Description:Binding affinity to BACE1 (unknown origin) by surface plasmon resonance spectroscopic analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2017
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50172104BDBM50172104(CHEMBL3808441)
Affinity DataKd:  8nMAssay Description:Binding affinity to BACE1 (unknown origin) by surface plasmon resonance spectroscopic analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2017
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50172106BDBM50172106(CHEMBL3809897)
Affinity DataKd:  11nMAssay Description:Binding affinity to BACE1 (unknown origin) by surface plasmon resonance spectroscopic analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2017
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50172101BDBM50172101(CHEMBL3808988)
Affinity DataKd:  16nMAssay Description:Binding affinity to BACE1 (unknown origin) by surface plasmon resonance spectroscopic analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2017
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50172105BDBM50172105(CHEMBL3808967)
Affinity DataKd:  25nMAssay Description:Binding affinity to BACE1 (unknown origin) by surface plasmon resonance spectroscopic analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2017
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 16047BDBM16047(EVNXXAEF | N-{(2R,4S,5S)-5-[(L-alpha-glutamyl-L-va...)
Affinity DataKd:  40nMAssay Description:Binding affinity to BACE1 by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50172103BDBM50172103(CHEMBL3808672)
Affinity DataKd:  140nMAssay Description:Binding affinity to BACE1 (unknown origin) by surface plasmon resonance spectroscopic analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2017
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50270768BDBM50270768(CHEMBL4128447)
Affinity DataKd:  169nMAssay Description:Binding affinity to BACE1 (unknown origin) by SPR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50270767BDBM50270767(CHEMBL4127062)
Affinity DataKd:  213nMAssay Description:Binding affinity to BACE1 (unknown origin) by SPR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50270766BDBM50270766(CHEMBL4127672)
Affinity DataKd:  554nMAssay Description:Binding affinity to BACE1 (unknown origin) by SPR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50270763BDBM50270763(CHEMBL4128586)
Affinity DataKd:  861nMAssay Description:Binding affinity to BACE1 (unknown origin) by SPR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50270756BDBM50270756(CHEMBL4128807)
Affinity DataKd:  1.03E+3nMAssay Description:Binding affinity to BACE1 (unknown origin) by SPR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50270762BDBM50270762(CHEMBL4128727)
Affinity DataKd:  1.23E+3nMAssay Description:Binding affinity to BACE1 (unknown origin) by SPR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50270759BDBM50270759(CHEMBL4127412)
Affinity DataKd:  1.33E+3nMAssay Description:Binding affinity to BACE1 (unknown origin) by SPR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50270764BDBM50270764(CHEMBL4127986)
Affinity DataKd:  1.43E+3nMAssay Description:Binding affinity to BACE1 (unknown origin) by SPR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50270761BDBM50270761(CHEMBL4129873)
Affinity DataKd:  1.44E+3nMAssay Description:Binding affinity to BACE1 (unknown origin) by SPR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50270757BDBM50270757(CHEMBL4126598)
Affinity DataKd:  1.74E+3nMAssay Description:Binding affinity to BACE1 (unknown origin) by SPR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50270765BDBM50270765(CHEMBL4127289)
Affinity DataKd:  1.75E+3nMAssay Description:Binding affinity to BACE1 (unknown origin) by SPR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50270770BDBM50270770(CHEMBL4126751)
Affinity DataKd:  1.84E+3nMAssay Description:Binding affinity to BACE1 (unknown origin) by SPR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50270760BDBM50270760(CHEMBL4127550)
Affinity DataKd:  1.88E+3nMAssay Description:Binding affinity to BACE1 (unknown origin) by SPR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50270769BDBM50270769(CHEMBL4128947)
Affinity DataKd:  2.14E+3nMAssay Description:Binding affinity to BACE1 (unknown origin) by SPR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50351919BDBM50351919(CHEMBL1821810)
Affinity DataKd:  4.20E+3nMAssay Description:Binding affinity to BACE1 after 90 seconds by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50351917BDBM50351917(CHEMBL1821808)
Affinity DataKd:  6.10E+3nMAssay Description:Binding affinity to BACE1 after 90 seconds by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50351942BDBM50351942(CHEMBL1821805)
Affinity DataKd:  7.20E+3nMAssay Description:Binding affinity to BACE1 after 90 seconds by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50351914BDBM50351914(CHEMBL1821803)
Affinity DataKd:  1.06E+4nMAssay Description:Binding affinity to BACE1 after 90 seconds by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50351941BDBM50351941(CHEMBL1821804)
Affinity DataKd:  1.08E+4nMAssay Description:Binding affinity to BACE1 after 90 seconds by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50351922BDBM50351922(CHEMBL1821813)
Affinity DataKd:  1.42E+4nMAssay Description:Binding affinity to BACE1 after 90 seconds by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 114543BDBM114543(carbamimidothioic acid (4-butoxy-3-chlorophenyl)me...)
Affinity DataKd:  1.50E+4nMAssay Description:Inhibition of BACE1 by fragment-based NMR screening methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 114543BDBM114543(carbamimidothioic acid (4-butoxy-3-chlorophenyl)me...)
Affinity DataKd:  1.50E+4nMAssay Description:Binding affinity to BACE1 by fragment-based NMR screening assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50351914BDBM50351914(CHEMBL1821803)
Affinity DataKd:  2.00E+4nMAssay Description:Binding affinity to BACE1 (unknown origin) by surface plasmon resonance spectroscopic analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2017
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50351913BDBM50351913(CHEMBL1821802)
Affinity DataKd:  2.26E+4nMAssay Description:Binding affinity to BACE1 after 90 seconds by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50351914BDBM50351914(CHEMBL1821803)
Affinity DataKd:  2.50E+4nMAssay Description:Binding affinity to BACE1 by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 16042BDBM16042(5-{[(5-aminopentyl)carbamoyl]methoxy}-3-N-[(1R)-1-...)
Affinity DataKd:  2.50E+4nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50493641BDBM50493641(CHEMBL2437454)
Affinity DataKd:  2.68E+4nMAssay Description:Binding affinity to human recombinant BACE1 expressed in Escherichia coli BL21(DE3) by isothermal titration calorimetry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50300240BDBM50300240(3-(3-chlorophenethyl)pyridin-2-amine | 3-[2-(3-chl...)
Affinity DataKd:  3.20E+4nMAssay Description:Binding affinity to BACE1 by fragment-based NMR screening assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50351913BDBM50351913(CHEMBL1821802)
Affinity DataKd:  3.40E+4nMAssay Description:Binding affinity to BACE1 by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50493642BDBM50493642(CHEMBL2437452)
Affinity DataKd:  3.66E+4nMAssay Description:Binding affinity to human recombinant BACE1 expressed in Escherichia coli BL21(DE3) by isothermal titration calorimetry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50351918BDBM50351918(CHEMBL1821809)
Affinity DataKd:  3.84E+4nMAssay Description:Binding affinity to BACE1 after 90 seconds by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50351912BDBM50351912(CHEMBL1821801)
Affinity DataKd:  3.88E+4nMAssay Description:Binding affinity to BACE1 after 90 seconds by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50379198BDBM50379198(CHEMBL2011277)
Affinity DataKd:  3.90E+4nMAssay Description:Binding affinity to BACE1 by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50372981BDBM50372981(CHEMBL428070)
Affinity DataKd:  6.00E+4nMAssay Description:Binding affinity to BACE1 by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 64871BDBM64871(N-(6-chloranylpyridin-3-yl)-4-fluoranyl-benzamide ...)
Affinity DataKd:  1.14E+5nMAssay Description:Binding affinity to BACE1 (unknown origin) by surface plasmon resonance spectroscopic analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2017
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50300226BDBM50300226(3-(3-Chlorobenzyl)-5-isobutyl-5-methyl-2-iminohyda...)
Affinity DataKd:  1.23E+5nMAssay Description:Inhibition of BACE1 by fragment-based NMR screening methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50300227BDBM50300227((2Z)-3-(3-chlorobenzyl)-2-imino-5,5-dimethylimidaz...)
Affinity DataKd:  2.00E+5nMAssay Description:Inhibition of BACE1 by fragment-based NMR screening methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50379206BDBM50379206(CHEMBL2011278)
Affinity DataKd:  2.00E+5nMAssay Description:Binding affinity to BACE1 by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50379206BDBM50379206(CHEMBL2011278)
Affinity DataKd:  2.00E+5nMAssay Description:Binding affinity to BACE1 by NMR-based differential chemical shift perturbation methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50351911BDBM50351911(CHEMBL1821800)
Affinity DataKd:  2.09E+5nMAssay Description:Binding affinity to BACE1 after 90 seconds by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50372980BDBM50372980(CHEMBL404150)
Affinity DataKd:  2.20E+5nMAssay Description:Binding affinity to BACE1 by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBeta-secretase 1(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50351910BDBM50351910(CHEMBL1821799)
Affinity DataKd:  2.66E+5nMAssay Description:Binding affinity to BACE1 after 90 seconds by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
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