Compile Data Set for Download or QSAR
Report error Found 43 of kd data for polymerid = 6461,7890,49000438,49000447,49000450,50002965
TargetD(1A) dopamine receptor(Human)
Va Medical Center

Curated by ChEMBL
LigandPNGBDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Affinity DataKd:  9.69E+3nMAssay Description:Equilibrium dissociation constant against recombinant Dopamine receptor D1A expressed in COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Va Medical Center

Curated by ChEMBL
LigandPNGBDBM50214407((6aR,9R)-N-((S)-1-((S)-1-((S)-2-carbamoylpyrrolidi...)
Affinity DataKd:  1.20E+3nMAssay Description:Displacement of [3H]SCH 23390 from dopamine D1 receptor in lamb striatum membrane after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Va Medical Center

Curated by ChEMBL
LigandPNGBDBM50214408((6aR,9S)-N-((S)-1-((S)-1-((S)-2-carbamoylpyrrolidi...)
Affinity DataKd:  700nMAssay Description:Displacement of [3H]SCH 23390 from dopamine D1 receptor in lamb striatum membrane after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Va Medical Center

Curated by ChEMBL
LigandPNGBDBM82247(SCH 23390,R(+) | CAS_87134-87-0 | CHEMBL2158641 | ...)
Affinity DataKd:  0.380nMAssay Description:Ability to inhibit the binding of [3H]-SCH- 23390 to canine striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Va Medical Center

Curated by ChEMBL
LigandPNGBDBM50022817(5-(4-Azido-phenyl)-8-iodo-3-methyl-2,3,4,5-tetrahy...)
Affinity DataKd:  0.150nMAssay Description:Ability to inhibit the binding of [3H]-SCH- 23390 to canine striatal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Va Medical Center

Curated by ChEMBL
LigandPNGBDBM50007422((R)-10,11-Dihydroxy-6-propyl-5,6,6a,7-tetrahydro-4...)
Affinity DataKd:  1.82E+3nMAssay Description:Equilibrium dissociation constant against recombinant Dopamine receptor D1A expressed in COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Va Medical Center

Curated by ChEMBL
LigandPNGBDBM50029051(4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol | ...)
Affinity DataKd:  5.00E+4nMAssay Description:Equilibrium dissociation constant against recombinant Dopamine receptor D1A expressed in COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Va Medical Center

Curated by ChEMBL
LigandPNGBDBM50001955(APOKYN | CHEMBL53 | (Apomorphine) 6-Methyl-5,6,6a,...)
Affinity DataKd:  680nMAssay Description:Equilibrium dissociation constant against recombinant Dopamine receptor D1A expressed in COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Va Medical Center

Curated by ChEMBL
LigandPNGBDBM50029050(4-[(1R)-1-hydroxy-2-(methylamino)ethyl]benzene-1,2...)
Affinity DataKd:  5.50E+4nMAssay Description:Equilibrium dissociation constant against recombinant Dopamine receptor D1A expressed in COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Va Medical Center

Curated by ChEMBL
LigandPNGBDBM50049796((S)-6-Chloro-7,8-dihydroxy-1-(4-hydroxy-phenyl)-2,...)
Affinity DataKd:  1.82E+3nMAssay Description:Equilibrium dissociation constant against recombinant Dopamine receptor D1A expressed in COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Va Medical Center

Curated by ChEMBL
LigandPNGBDBM50004921(CHEMBL34095 | (R)-3-Allyl-6-bromo-7,8-dihydroxy-1-...)
Affinity DataKd:  384nMAssay Description:Equilibrium dissociation constant against recombinant Dopamine receptor D1A expressed in COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Va Medical Center

Curated by ChEMBL
LigandPNGBDBM50214405((6aR,9R)-N-((S)-1-((S)-1-((S)-2-carbamoylpyrrolidi...)
Affinity DataKd:  7.80E+3nMAssay Description:Displacement of [3H]SCH 23390 from dopamine D1 receptor in lamb striatum membrane after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Va Medical Center

Curated by ChEMBL
LigandPNGBDBM55121(cid_65340 | Dopamine | SMR000059081 | 4-(2-aminoet...)
Affinity DataKd:  2.50E+3nMAssay Description:Equilibrium dissociation constant against recombinant Dopamine receptor D1A expressed in COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetD(1A) dopamine receptor(Human)
Va Medical Center

Curated by ChEMBL
LigandPNGBDBM50025206((6,7-Dihydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)...)
Affinity DataKd:  4.60E+3nMAssay Description:Equilibrium dissociation constant against recombinant Dopamine receptor D1A expressed in COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Va Medical Center

Curated by ChEMBL
LigandPNGBDBM50004822(CHEMBL24077 | SKF 38393 (+) | SK-383933 | R(+)SKF ...)
Affinity DataKd:  150nMAssay Description:Equilibrium dissociation constant against recombinant Dopamine receptor D1A expressed in COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Va Medical Center

Curated by ChEMBL
LigandPNGBDBM60917(MLS001401388 | 9-chloro-5-(4-hydroxyphenyl)-2,3,4,...)
Affinity DataKd:  28nMAssay Description:Equilibrium dissociation constant against recombinant Dopamine receptor D1A expressed in COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Bovine)
Sandoz Pharma

Curated by ChEMBL
LigandPNGBDBM85099(SDZ SER 082 FUMARATE | CAS_141474-54-6 | SDZ SER-0...)
Affinity DataKd: <1.00E+4nMAssay Description:Binding affinity towards Dopamine receptor D1 of calf striatal tissue using [3H]SCH-23390More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Bovine)
Sandoz Pharma

Curated by ChEMBL
LigandPNGBDBM85099(SDZ SER 082 FUMARATE | CAS_141474-54-6 | SDZ SER-0...)
Affinity DataKd: <1.00E+4nMAssay Description:Binding affinity towards Dopamine receptor D1 of calf striatal tissue using [3H]SCH-23390More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Va Medical Center

Curated by ChEMBL
LigandPNGBDBM50601551(CHEMBL5207281)
Affinity DataKd:  0.230nMAssay Description:Displacement of [3H]SCH23390 from human D1 receptor stably expressed in HEK293T cells co-expressing luciferase and CEK incubated for 60 mins by scint...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetD(1A) dopamine receptor(Human)
Va Medical Center

Curated by ChEMBL
LigandPNGBDBM50601567(CHEMBL5206565)
Affinity DataKd:  0.230nMAssay Description:Displacement of [3H]SCH23390 from human D1 receptor stably expressed in HEK293T cells co-expressing luciferase and CEK incubated for 60 mins by scint...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetD(1A) dopamine receptor(Human)
Va Medical Center

Curated by ChEMBL
LigandPNGBDBM50601574(CHEMBL5201074)
Affinity DataKd:  0.230nMAssay Description:Displacement of [3H]SCH23390 from human D1 receptor stably expressed in HEK293T cells co-expressing luciferase and CEK incubated for 60 mins by scint...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetD(1A) dopamine receptor(Human)
Va Medical Center

Curated by ChEMBL
LigandPNGBDBM50568740(CHEMBL4860528)
Affinity DataKd:  0.230nMAssay Description:Displacement of [3H]SCH23390 from human D1 receptor stably expressed in HEK293T cells co-expressing luciferase and CEK incubated for 60 mins by scint...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetD(1A) dopamine receptor(Human)
Va Medical Center

Curated by ChEMBL
LigandPNGBDBM50083558(CHEMBL3423403)
Affinity DataKd:  1.50E+4nMAssay Description:Displacement of [3H]-SCH23390 from dopamine D1 receptor (unknown origin) expressed in sheep striatum membranes after 1.5 hrs by scintillation countin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50016792(SK-83566 | 8-Bromo-3-methyl-5-phenyl-2,3,4,5-tetra...)
Affinity DataKd:  2.30nMAssay Description:In vitro binding affinity to the rat striatal homogenate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50016795(CHEMBL287504 | 3-Methyl-5-phenyl-2,3,4,5-tetrahydr...)
Affinity DataKd:  197nMAssay Description:In vitro binding affinity to the rat striatal homogenate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50016794(CHEMBL34170 | 8-Chloro-5-(4-iodo-phenyl)-3-methyl-...)
Affinity DataKd:  1.40nMAssay Description:In vitro binding affinity towards Dopamine receptor D1 by displacing [125I]FISCH radioligand in rat striatal homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50033383((S)-4-((3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)m...)
Affinity DataKd:  0.300nMAssay Description:Binding affinity against dopamine receptor D1 in rat striatum using [3H]SCH-23390 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Va Medical Center

Curated by ChEMBL
LigandPNGBDBM50083544(CHEMBL3423409)
Affinity DataKd:  3.30E+3nMAssay Description:Displacement of [3H]-SCH23390 from dopamine D1 receptor (unknown origin) expressed in sheep striatum membranes after 1.5 hrs by scintillation countin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Va Medical Center

Curated by ChEMBL
LigandPNGBDBM50083546(CHEMBL3423408)
Affinity DataKd:  4.00E+3nMAssay Description:Displacement of [3H]-SCH23390 from dopamine D1 receptor (unknown origin) expressed in sheep striatum membranes after 1.5 hrs by scintillation countin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Va Medical Center

Curated by ChEMBL
LigandPNGBDBM50083550(CHEMBL3423407)
Affinity DataKd:  1.30E+3nMAssay Description:Displacement of [3H]-SCH23390 from dopamine D1 receptor (unknown origin) expressed in sheep striatum membranes after 1.5 hrs by scintillation countin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Va Medical Center

Curated by ChEMBL
LigandPNGBDBM50083551(CHEMBL3423406)
Affinity DataKd:  1.90E+3nMAssay Description:Displacement of [3H]-SCH23390 from dopamine D1 receptor (unknown origin) expressed in sheep striatum membranes after 1.5 hrs by scintillation countin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Va Medical Center

Curated by ChEMBL
LigandPNGBDBM50083554(CHEMBL3423405)
Affinity DataKd:  3.40E+3nMAssay Description:Displacement of [3H]-SCH23390 from dopamine D1 receptor (unknown origin) expressed in sheep striatum membranes after 1.5 hrs by scintillation countin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Va Medical Center

Curated by ChEMBL
LigandPNGBDBM50083555(CHEMBL3423404)
Affinity DataKd:  1.20E+3nMAssay Description:Displacement of [3H]-SCH23390 from dopamine D1 receptor (unknown origin) expressed in sheep striatum membranes after 1.5 hrs by scintillation countin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Va Medical Center

Curated by ChEMBL
LigandPNGBDBM50016003(CHEMBL150800 | R-[5-(4-Azido-phenyl)-8-iodo-3-meth...)
Affinity DataKd:  0.280nMAssay Description:Ability to inhibit [3H]-SCH- 23390 binding to Dopamine receptor D1 of canine striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Va Medical Center

Curated by ChEMBL
LigandPNGBDBM50083509(CHEMBL3423402)
Affinity DataKd:  2.90E+3nMAssay Description:Displacement of [3H]-SCH23390 from dopamine D1 receptor (unknown origin) expressed in sheep striatum membranes after 1.5 hrs by scintillation countin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Va Medical Center

Curated by ChEMBL
LigandPNGBDBM50083559(CHEMBL3423401)
Affinity DataKd:  3.80E+4nMAssay Description:Displacement of [3H]-SCH23390 from dopamine D1 receptor (unknown origin) expressed in sheep striatum membranes after 1.5 hrs by scintillation countin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Va Medical Center

Curated by ChEMBL
LigandPNGBDBM50083560(CHEMBL3423400)
Affinity DataKd:  2.70E+4nMAssay Description:Displacement of [3H]-SCH23390 from dopamine D1 receptor (unknown origin) expressed in sheep striatum membranes after 1.5 hrs by scintillation countin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Va Medical Center

Curated by ChEMBL
LigandPNGBDBM50083540(CHEMBL3423410)
Affinity DataKd:  1.50E+3nMAssay Description:Displacement of [3H]-SCH23390 from dopamine D1 receptor (unknown origin) expressed in sheep striatum membranes assessed as high affinity constant aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Va Medical Center

Curated by ChEMBL
LigandPNGBDBM50083510(CHEMBL3423411)
Affinity DataKd:  1.60E+3nMAssay Description:Displacement of [3H]-SCH23390 from dopamine D1 receptor (unknown origin) expressed in sheep striatum membranes assessed as high affinity constant aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Va Medical Center

Curated by ChEMBL
LigandPNGBDBM50083540(CHEMBL3423410)
Affinity DataKd:  2.40E+4nMAssay Description:Displacement of [3H]-SCH23390 from dopamine D1 receptor (unknown origin) expressed in sheep striatum membranes assessed as low affinity constant afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Va Medical Center

Curated by ChEMBL
LigandPNGBDBM50083510(CHEMBL3423411)
Affinity DataKd:  3.00E+4nMAssay Description:Displacement of [3H]-SCH23390 from dopamine D1 receptor (unknown origin) expressed in sheep striatum membranes assessed as low affinity constant afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2016
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Va Medical Center

Curated by ChEMBL
LigandPNGBDBM50214403((6aR,9R)-N-((S)-1-((S)-1-(3-carbamoylpiperidin-1-y...)
Affinity DataKd:  700nMAssay Description:Displacement of [3H]SCH 23390 from dopamine D1 receptor in lamb striatum membrane after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Va Medical Center

Curated by ChEMBL
LigandPNGBDBM50214401((6aR,9R)-N-((S)-1-((S)-1-((S)-2-carbamoylpyrrolidi...)
Affinity DataKd:  600nMAssay Description:Displacement of [3H]SCH 23390 from dopamine D1 receptor in lamb striatum membrane after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed