Compile Data Set for Download or QSAR
Report error Found 164 of kd data for polymerid = 808,50003589
TargetAngiopoietin-1 receptor(Human)
University Hospital and University of Zurich

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 239621BDBM239621(US9394309, 147 | US9394309, 74)
Affinity DataKd:  1.60nMAssay Description:Binding affinity to TIE2 (unknown origin) assessed as dissociation constant by KINOME scan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetAngiopoietin-1 receptor(Human)
University Hospital and University of Zurich

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50355504BDBM50355504(CHEMBL1908393)
Affinity DataKd:  3.10nMAssay Description:Binding constant for TIE2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
University Hospital and University of Zurich

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 586640BDBM586640(D3RKN_29)
Affinity DataKd:  3.40nMAssay Description:D3R2025More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2023
Entry Details
D3R

TargetAngiopoietin-1 receptor(Human)
University Hospital and University of Zurich

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 13533BDBM13533(1-[5-tert-butyl-2-(p-tolyl)pyrazol-3-yl]-3-[4-(2-m...)
Affinity DataKd:  11nMAssay Description:Average Binding Constant for TEK; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
University Hospital and University of Zurich

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 31085BDBM31085(cid_11409972 | 1-[4-[(4-ethylpiperazin-1-yl)methyl...)
Affinity DataKd:  19nMAssay Description:Binding constant for TIE2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
University Hospital and University of Zurich

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 31085BDBM31085(cid_11409972 | 1-[4-[(4-ethylpiperazin-1-yl)methyl...)
Affinity DataKd:  19nMAssay Description:Binding constant for TIE2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
University Hospital and University of Zurich

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 31085BDBM31085(cid_11409972 | 1-[4-[(4-ethylpiperazin-1-yl)methyl...)
Affinity DataKd:  19nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2011
Entry Details
PCBioAssay
TargetAngiopoietin-1 receptor(Human)
University Hospital and University of Zurich

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 13533BDBM13533(1-[5-tert-butyl-2-(p-tolyl)pyrazol-3-yl]-3-[4-(2-m...)
Affinity DataKd:  20nMAssay Description:Binding constant for TIE2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
University Hospital and University of Zurich

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 13533BDBM13533(1-[5-tert-butyl-2-(p-tolyl)pyrazol-3-yl]-3-[4-(2-m...)
Affinity DataKd:  20nMAssay Description:Binding constant for TIE2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
University Hospital and University of Zurich

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 13533BDBM13533(1-[5-tert-butyl-2-(p-tolyl)pyrazol-3-yl]-3-[4-(2-m...)
Affinity DataKd:  20nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2011
Entry Details
PCBioAssay
TargetAngiopoietin-1 receptor(Human)
University Hospital and University of Zurich

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50349213BDBM50349213(CHEMBL1808264 | D3RKN_42)
Affinity DataKd:  24nMAssay Description:D3R2025More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2023
Entry Details
D3R

TargetAngiopoietin-1 receptor(Human)
University Hospital and University of Zurich

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 586665BDBM586665(D3RKN_118)
Affinity DataKd:  27nMAssay Description:D3R2025More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2023
Entry Details
D3R

TargetAngiopoietin-1 receptor(Human)
University Hospital and University of Zurich

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 482158BDBM482158(TAE684 | BDBM50242742)
Affinity DataKd:  46nMAssay Description:Binding constant for TIE2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
University Hospital and University of Zurich

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 124970BDBM124970(US8765747, 2)
Affinity DataKd:  57nMAssay Description:KINOMEscan (Ambit Biosciences, San Diego, Calif.), a high-throughput method for screening small molecular agents against a large panel of human kinas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2014
Entry Details
US Patent

TargetAngiopoietin-1 receptor(Human)
University Hospital and University of Zurich

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 586664BDBM586664(D3RKN_117)
Affinity DataKd:  92nMAssay Description:D3R2025More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2023
Entry Details
D3R

TargetAngiopoietin-1 receptor(Human)
University Hospital and University of Zurich

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 586660BDBM586660(D3RKN_98)
Affinity DataKd:  93nMAssay Description:D3R2025More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2023
Entry Details
D3R

TargetAngiopoietin-1 receptor(Human)
University Hospital and University of Zurich

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 31096BDBM31096(CHEMBL290084 | Staurosporine | cid_451705 | US2024...)
Affinity DataKd:  140nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2011
Entry Details
PCBioAssay
TargetAngiopoietin-1 receptor(Human)
University Hospital and University of Zurich

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 2579BDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataKd:  140nMAssay Description:Binding constant for TIE2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
University Hospital and University of Zurich

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 2579BDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataKd:  140nMAssay Description:Binding constant for TIE2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
University Hospital and University of Zurich

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50331096BDBM50331096(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-6-methoxy-7...)
Affinity DataKd:  140nMAssay Description:Binding constant for TIE2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
University Hospital and University of Zurich

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 586676BDBM586676(D3RKN_124)
Affinity DataKd:  200nMAssay Description:D3R2025More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2023
Entry Details
D3R

TargetAngiopoietin-1 receptor(Human)
University Hospital and University of Zurich

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 2579BDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataKd:  240nMAssay Description:Average Binding Constant for TEK; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
University Hospital and University of Zurich

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50306682BDBM50306682((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)
Affinity DataKd:  270nMAssay Description:Binding constant for TIE2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
University Hospital and University of Zurich

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 6568BDBM6568(PD-173955 | CHEMBL386051 | 6-(2,6-dichlorophenyl)-...)
Affinity DataKd:  280nMAssay Description:Binding constant for TIE2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
University Hospital and University of Zurich

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 31093BDBM31093(cid_11712649 | 4-[[7-[2,6-bis(fluoranyl)phenyl]-9-...)
Affinity DataKd:  300nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2011
Entry Details
PCBioAssay
TargetAngiopoietin-1 receptor(Human)
University Hospital and University of Zurich

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 31093BDBM31093(cid_11712649 | 4-[[7-[2,6-bis(fluoranyl)phenyl]-9-...)
Affinity DataKd:  300nMAssay Description:Binding constant for TIE2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
University Hospital and University of Zurich

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 31093BDBM31093(cid_11712649 | 4-[[7-[2,6-bis(fluoranyl)phenyl]-9-...)
Affinity DataKd:  300nMAssay Description:Binding constant for TIE2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
University Hospital and University of Zurich

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 25117BDBM25117(AG-013736 | N-methyl-2-({3-[(E)-2-(pyridin-2-yl)et...)
Affinity DataKd:  310nMAssay Description:Binding constant for TIE2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
University Hospital and University of Zurich

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 60665BDBM60665(US9145414, R406 | US9212178, R406 | BDBM50249542 |...)
Affinity DataKd:  310nMAssay Description:Binding constant for TIE2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
University Hospital and University of Zurich

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299148BDBM50299148(1-{4-[(3-cyclopropyl-1H-pyrazol-5-yl)amino]pyrrolo...)
Affinity DataKd:  350nMAssay Description:Binding affinity to TIE2 (unknown origin) by phage based competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetAngiopoietin-1 receptor(Human)
University Hospital and University of Zurich

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50368452BDBM50368452(CHEMBL4168305)
Affinity DataKd:  370nMAssay Description:Binding affinity to human TIE2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
University Hospital and University of Zurich

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50505541BDBM50505541(CHEMBL4465866)
Affinity DataKd:  395nMAssay Description:Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged TEK (unknown origin) (771 to 1124 residues) expressed in baculovirus infec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
University Hospital and University of Zurich

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50505542BDBM50505542(CHEMBL4576489)
Affinity DataKd:  408nMAssay Description:Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged TEK (unknown origin) (771 to 1124 residues) expressed in baculovirus infec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
University Hospital and University of Zurich

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50184807BDBM50184807((R)-1-(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-me...)
Affinity DataKd:  440nMAssay Description:Binding constant for TIE2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
University Hospital and University of Zurich

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 13534BDBM13534(VX680 | N-[4-[[4-(4-methylpiperazino)-6-[(5-methyl...)
Affinity DataKd:  450nMAssay Description:Binding constant for TIE2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
University Hospital and University of Zurich

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 13534BDBM13534(VX680 | N-[4-[[4-(4-methylpiperazino)-6-[(5-methyl...)
Affinity DataKd:  450nMAssay Description:Binding constant for TIE2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
University Hospital and University of Zurich

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21079BDBM21079(1-[4-(3-azanyl-1H-indazol-4-yl)phenyl]-3-(2-fluora...)
Affinity DataKd:  450nMAssay Description:Binding constant for TIE2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
University Hospital and University of Zurich

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 13534BDBM13534(VX680 | N-[4-[[4-(4-methylpiperazino)-6-[(5-methyl...)
Affinity DataKd:  450nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2011
Entry Details
PCBioAssay
TargetAngiopoietin-1 receptor(Human)
University Hospital and University of Zurich

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21079BDBM21079(1-[4-(3-azanyl-1H-indazol-4-yl)phenyl]-3-(2-fluora...)
Affinity DataKd:  450nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2011
Entry Details
PCBioAssay
TargetAngiopoietin-1 receptor(Human)
University Hospital and University of Zurich

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21079BDBM21079(1-[4-(3-azanyl-1H-indazol-4-yl)phenyl]-3-(2-fluora...)
Affinity DataKd:  450nMAssay Description:Binding constant for TIE2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
University Hospital and University of Zurich

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50308060BDBM50308060(CEP-701 | 16-hydroxy-16-(hydroxymethyl)-15-methyl-...)
Affinity DataKd:  630nMAssay Description:Binding affinity to TIE2More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2011
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
University Hospital and University of Zurich

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50308060BDBM50308060(CEP-701 | 16-hydroxy-16-(hydroxymethyl)-15-methyl-...)
Affinity DataKd:  630nMAssay Description:Binding constant for TIE2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
University Hospital and University of Zurich

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 6866BDBM6866(1-Acyl-1H-[1,2,4]triazole-3,5-diamine Analogue 3b ...)
Affinity DataKd:  950nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2011
Entry Details
PCBioAssay
TargetAngiopoietin-1 receptor(Human)
University Hospital and University of Zurich

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 6866BDBM6866(1-Acyl-1H-[1,2,4]triazole-3,5-diamine Analogue 3b ...)
Affinity DataKd:  950nMAssay Description:Binding constant for TIE2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
University Hospital and University of Zurich

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50588796BDBM50588796(CHEMBL5197792)
Affinity DataKd:  950nMAssay Description:Binding affinity to TIE2 (unknown origin) assessed as dissociation constant by competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetAngiopoietin-1 receptor(Human)
University Hospital and University of Zurich

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21BDBM21(VANDETANIB | N-(4-bromo-2-fluorophenyl)-6-methoxy-...)
Affinity DataKd:  1.00E+3nMAssay Description:Binding constant for TIE2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
University Hospital and University of Zurich

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21BDBM21(VANDETANIB | N-(4-bromo-2-fluorophenyl)-6-methoxy-...)
Affinity DataKd:  1.00E+3nMAssay Description:Binding constant for TIE2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
University Hospital and University of Zurich

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21BDBM21(VANDETANIB | N-(4-bromo-2-fluorophenyl)-6-methoxy-...)
Affinity DataKd:  1.00E+3nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2011
Entry Details
PCBioAssay
TargetAngiopoietin-1 receptor(Human)
University Hospital and University of Zurich

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50237710BDBM50237710(AMN 107 | AMN107 | 4-methyl-N-[3-(4-methyl-1H-imid...)
Affinity DataKd:  1.00E+3nMAssay Description:Binding constant for TIE2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
University Hospital and University of Zurich

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50355496BDBM50355496(CHEMBL1908397)
Affinity DataKd:  1.10E+3nMAssay Description:Binding constant for TIE2 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed
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