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TargetD-3-phosphoglycerate dehydrogenase(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652792BDBM50652792(CHEMBL3752910)
Affinity DataKd:  9.40nMAssay Description:Binding affinity to human PHGDH incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50230355BDBM50230355(CHEMBL4061884)
Affinity DataKd:  180nMAssay Description:Binding affinity to PHGDH (unknown origin) by surface plasma resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2019
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50230355BDBM50230355(CHEMBL4061884)
Affinity DataKd:  180nMAssay Description:Binding affinity to PHGDH (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50230355BDBM50230355(CHEMBL4061884)
Affinity DataKd:  180nMAssay Description:Binding affinity to PHGDH (unknown origin) by surface plasma resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2020
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50230355BDBM50230355(CHEMBL4061884)
Affinity DataKd:  180nMAssay Description:Binding affinity to PHGDH (unknown origin) by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50616372BDBM50616372(CHEMBL5436320)
Affinity DataKd:  2.33E+3nMAssay Description:Binding affinity to PHGDH (unknown origin) assessed as dissociation constant incubated for 60 mins by microscale thermophoresis analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50616372BDBM50616372(CHEMBL5436320)
Affinity DataKd:  2.48E+3nMAssay Description:Binding affinity to his-tagged PHGDH (127 to 722 residues) (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 209927BDBM209927(PKUMDL-WQ-2203)
Affinity DataKd:  7.22E+3nMpH: 7.4Assay Description:The binding affinities of compounds towards PHGDH were assayed using the SPR-based Biacore T200 instrument (GE Healthcare). PHGDH was immobilized on ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2017
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652793BDBM50652793(CHEMBL5653589)
Affinity DataKd:  1.50E+4nMAssay Description:Binding affinity to human PHGDH incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50607970BDBM50607970(CHEMBL5270272)
Affinity DataKd:  1.52E+4nMAssay Description:Binding affinity to human PHGDH expressed in Escherichia coli BL21 incubated for 30 mins by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 209926BDBM209926(PKUMDL-WQ-2202)
Affinity DataKd:  2.90E+4nMpH: 7.4Assay Description:The binding affinities of compounds towards PHGDH were assayed using the SPR-based Biacore T200 instrument (GE Healthcare). PHGDH was immobilized on ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2017
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 209925BDBM209925(PKUMDL-WQ-2201)
Affinity DataKd:  6.69E+4nMpH: 7.4Assay Description:The binding affinities of compounds towards PHGDH were assayed using the SPR-based Biacore T200 instrument (GE Healthcare). PHGDH was immobilized on ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2017
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50519097BDBM50519097(CHEMBL4574949)
Affinity DataKd:  1.05E+5nMAssay Description:Binding affinity to N-terminal His6-tagged human PHGDH (4 to 315 residues)by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50519142BDBM50519142(CHEMBL4548832)
Affinity DataKd:  1.44E+5nMAssay Description:Binding affinity to N-terminal His6-tagged human PHGDH (4 to 315 residues)by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50607972BDBM50607972(Benzo[B]Thiophene-2-Carboxamide | CHEMBL538197)
Affinity DataKd:  4.70E+5nMAssay Description:Binding affinity to PHGDH (unknown origin) by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50232876BDBM50232876(CHEMBL4094048)
Affinity DataKd:  1.30E+6nMAssay Description:Binding affinity to human PHGDH (3 to 314 residues) expressed in Escherichia coli Rosetta (DE3) by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetD-3-phosphoglycerate dehydrogenase(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50232874BDBM50232874(CHEMBL4074617)
Affinity DataKd:  1.50E+6nMAssay Description:Binding affinity to human PHGDH ( 1 to 533 residues) expressed in Escherichia coli Rosetta (DE3) by Sypro-orange dye based differential scanning fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetD-3-phosphoglycerate dehydrogenase(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50232879BDBM50232879(CHEMBL326430)
Affinity DataKd:  1.50E+6nMAssay Description:Binding affinity to human N-terminal His6-tagged truncated PHGDH (3 to 314 residues) expressed in Escherichia coli Rosetta (DE3) by ITC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2019
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50232879BDBM50232879(CHEMBL326430)
Affinity DataKd:  1.50E+6nMAssay Description:Binding affinity to human PHGDH (3 to 314 residues) expressed in Escherichia coli Rosetta (DE3) by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50232874BDBM50232874(CHEMBL4074617)
Affinity DataKd:  1.60E+6nMAssay Description:Binding affinity to human PHGDH (3 to 314 residues) expressed in Escherichia coli Rosetta (DE3) by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetD-3-phosphoglycerate dehydrogenase(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50232874BDBM50232874(CHEMBL4074617)
Affinity DataKd:  1.60E+6nMAssay Description:Binding affinity to human N-terminal His6-tagged truncated PHGDH (3 to 314 residues) expressed in Escherichia coli Rosetta (DE3) by ITC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetD-3-phosphoglycerate dehydrogenase(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50232876BDBM50232876(CHEMBL4094048)
Affinity DataKd:  2.80E+6nMAssay Description:Binding affinity to human N-terminal His6-tagged truncated PHGDH (3 to 314 residues) expressed in Escherichia coli Rosetta (DE3) by ITC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetD-3-phosphoglycerate dehydrogenase(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50232873BDBM50232873(CHEMBL4084029)
Affinity DataKd:  5.80E+6nMAssay Description:Binding affinity to human PHGDH (3 to 314 residues) expressed in Escherichia coli Rosetta (DE3) by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50232873BDBM50232873(CHEMBL4084029)
Affinity DataKd:  5.80E+6nMAssay Description:Binding affinity to human N-terminal His6-tagged truncated PHGDH (3 to 314 residues) expressed in Escherichia coli Rosetta (DE3) by ITC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2019
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50232875BDBM50232875(CHEMBL1901807)
Affinity DataKd:  5.90E+6nMAssay Description:Binding affinity to human PHGDH (3 to 314 residues) expressed in Escherichia coli Rosetta (DE3) by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50232875BDBM50232875(CHEMBL1901807)
Affinity DataKd:  5.90E+6nMAssay Description:Binding affinity to human N-terminal His6-tagged truncated PHGDH (3 to 314 residues) expressed in Escherichia coli Rosetta (DE3) by ITC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2019
Entry Details Article
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50232880BDBM50232880(Benzo[D]Isoxazol-3-Ol | CHEMBL444173)
Affinity DataKd:  6.50E+6nMAssay Description:Binding affinity to human PHGDH (3 to 314 residues) expressed in Escherichia coli Rosetta (DE3) by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetD-3-phosphoglycerate dehydrogenase(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50232880BDBM50232880(Benzo[D]Isoxazol-3-Ol | CHEMBL444173)
Affinity DataKd:  6.50E+6nMAssay Description:Binding affinity to human N-terminal His6-tagged truncated PHGDH (3 to 314 residues) expressed in Escherichia coli Rosetta (DE3) by ITC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetD-3-phosphoglycerate dehydrogenase(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50011537BDBM50011537(CHEMBL3262562)
Affinity DataKd:  9.30E+6nMAssay Description:Binding affinity to human PHGDH (3 to 314 residues) expressed in Escherichia coli Rosetta (DE3) by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetD-3-phosphoglycerate dehydrogenase(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50011537BDBM50011537(CHEMBL3262562)
Affinity DataKd:  9.30E+6nMAssay Description:Binding affinity to human N-terminal His6-tagged truncated PHGDH (3 to 314 residues) expressed in Escherichia coli Rosetta (DE3) by ITC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetD-3-phosphoglycerate dehydrogenase(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50455628BDBM50455628(CHEMBL4216063)
Affinity DataKd:  1.11E+7nMAssay Description:Binding affinity to human PHGDH (3 to 314 residues) expressed in Escherichia coli Rosetta (DE3) by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetD-3-phosphoglycerate dehydrogenase(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50607974BDBM50607974(CHEMBL5275733)
Affinity DataKd:  1.15E+7nMAssay Description:Binding affinity to human PHGDH (3 to 314 residues) expressed in Escherichia coli Rosetta (DE3) by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 7887BDBM7887(1-benzylimidazole | 1-Benzylimidazole (BI) | CHEMB...)
Affinity DataKd:  1.18E+7nMAssay Description:Binding affinity to human PHGDH (3 to 314 residues) expressed in Escherichia coli Rosetta (DE3) by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50365134BDBM50365134(CHEMBL1949840)
Affinity DataKd:  1.28E+7nMAssay Description:Binding affinity to human PHGDH (3 to 314 residues) expressed in Escherichia coli Rosetta (DE3) by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50607973BDBM50607973(CHEMBL5278022)
Affinity DataKd:  1.66E+7nMAssay Description:Binding affinity to human PHGDH (3 to 314 residues) expressed in Escherichia coli Rosetta (DE3) by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetD-3-phosphoglycerate dehydrogenase(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50607975BDBM50607975(CHEMBL5285114)
Affinity DataKd:  2.62E+7nMAssay Description:Binding affinity to human PHGDH (3 to 314 residues) expressed in Escherichia coli Rosetta (DE3) by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)