TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Ambit Biosciences
Curated by PubChem BioAssay
Ambit Biosciences
Curated by PubChem BioAssay
Affinity DataKd: 7.30E+6nMAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Ambit Biosciences
Curated by PubChem BioAssay
Ambit Biosciences
Curated by PubChem BioAssay
Affinity DataKd: 233nMpH: 7.5 T: 2°CAssay Description:For ERK1 and ERK2, the buffer contained 20 mM HEPES (pH 7.5), 150 mM NaCl and 0.5 mM TCEP. For haspin, the buffer contained 20 mM HEPES (pH 7.5), 250...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Ambit Biosciences
Curated by PubChem BioAssay
Ambit Biosciences
Curated by PubChem BioAssay
Affinity DataKd: 300nMpH: 7.5 T: 2°CAssay Description:For ERK1 and ERK2, the buffer contained 20 mM HEPES (pH 7.5), 150 mM NaCl and 0.5 mM TCEP. For haspin, the buffer contained 20 mM HEPES (pH 7.5), 250...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 1(Mus musculus (Mouse))
University Of Maryland, Baltimore
US Patent
University Of Maryland, Baltimore
US Patent
Affinity DataKd: 5.00E+3nMAssay Description:CADD and biological testing to identify compounds that interact with novel ERK substrate docking sites. The known ERK2 docking sites include the DRS ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 1(Mus musculus (Mouse))
University Of Maryland, Baltimore
US Patent
University Of Maryland, Baltimore
US Patent
Affinity DataKd: 3.30E+3nMAssay Description:CADD and biological testing to identify compounds that interact with novel ERK substrate docking sites. The known ERK2 docking sites include the DRS ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 1(Mus musculus (Mouse))
University Of Maryland, Baltimore
US Patent
University Of Maryland, Baltimore
US Patent
Affinity DataKd: 1.50E+3nMAssay Description:CADD and biological testing to identify compounds that interact with novel ERK substrate docking sites. The known ERK2 docking sites include the DRS ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 1(Mus musculus (Mouse))
University Of Maryland, Baltimore
US Patent
University Of Maryland, Baltimore
US Patent
Affinity DataKd: 2.40E+3nMAssay Description:CADD and biological testing to identify compounds that interact with novel ERK substrate docking sites. The known ERK2 docking sites include the DRS ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 1(Mus musculus (Mouse))
University Of Maryland, Baltimore
US Patent
University Of Maryland, Baltimore
US Patent
Affinity DataKd: 130nMAssay Description:CADD and biological testing to identify compounds that interact with novel ERK substrate docking sites. The known ERK2 docking sites include the DRS ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 1(Mus musculus (Mouse))
University Of Maryland, Baltimore
US Patent
University Of Maryland, Baltimore
US Patent
Affinity DataKd: 1.30E+3nMAssay Description:CADD and biological testing to identify compounds that interact with novel ERK substrate docking sites. The known ERK2 docking sites include the DRS ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 1(Mus musculus (Mouse))
University Of Maryland, Baltimore
US Patent
University Of Maryland, Baltimore
US Patent
Affinity DataKd: 170nMAssay Description:CADD and biological testing to identify compounds that interact with novel ERK substrate docking sites. The known ERK2 docking sites include the DRS ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 1(Mus musculus (Mouse))
University Of Maryland, Baltimore
US Patent
University Of Maryland, Baltimore
US Patent
Affinity DataKd: 9.30E+3nMAssay Description:CADD and biological testing to identify compounds that interact with novel ERK substrate docking sites. The known ERK2 docking sites include the DRS ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 1(Mus musculus (Mouse))
University Of Maryland, Baltimore
US Patent
University Of Maryland, Baltimore
US Patent
Affinity DataKd: 6.00E+3nMAssay Description:CADD and biological testing to identify compounds that interact with novel ERK substrate docking sites. The known ERK2 docking sites include the DRS ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 1(Mus musculus (Mouse))
University Of Maryland, Baltimore
US Patent
University Of Maryland, Baltimore
US Patent
Affinity DataKd: 1.02E+4nMAssay Description:CADD and biological testing to identify compounds that interact with novel ERK substrate docking sites. The known ERK2 docking sites include the DRS ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 1(Mus musculus (Mouse))
University Of Maryland, Baltimore
US Patent
University Of Maryland, Baltimore
US Patent
Affinity DataKd: 3.70E+3nMAssay Description:CADD and biological testing to identify compounds that interact with novel ERK substrate docking sites. The known ERK2 docking sites include the DRS ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 1(Mus musculus (Mouse))
University Of Maryland, Baltimore
US Patent
University Of Maryland, Baltimore
US Patent
Affinity DataKd: 400nMAssay Description:CADD and biological testing to identify compounds that interact with novel ERK substrate docking sites. The known ERK2 docking sites include the DRS ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 1(Mus musculus (Mouse))
University Of Maryland, Baltimore
US Patent
University Of Maryland, Baltimore
US Patent
Affinity DataKd: 6.80E+3nMAssay Description:CADD and biological testing to identify compounds that interact with novel ERK substrate docking sites. The known ERK2 docking sites include the DRS ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 1(Mus musculus (Mouse))
University Of Maryland, Baltimore
US Patent
University Of Maryland, Baltimore
US Patent
Affinity DataKd: 1.40E+3nMAssay Description:CADD and biological testing to identify compounds that interact with novel ERK substrate docking sites. The known ERK2 docking sites include the DRS ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 1(Mus musculus (Mouse))
University Of Maryland, Baltimore
US Patent
University Of Maryland, Baltimore
US Patent
Affinity DataKd: 6nMT: 2°CAssay Description:The SAR (Structure Activity Relationship) for ERK ligands covered by
this invention was interrogated using the TdF (Temperature Dependence
Fluoresc...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 1(Mus musculus (Mouse))
University Of Maryland, Baltimore
US Patent
University Of Maryland, Baltimore
US Patent
Affinity DataKd: 0.700nMT: 2°CAssay Description:The SAR (Structure Activity Relationship) for ERK ligands covered by
this invention was interrogated using the TdF (Temperature Dependence
Fluoresc...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 1(Mus musculus (Mouse))
University Of Maryland, Baltimore
US Patent
University Of Maryland, Baltimore
US Patent
Affinity DataKd: 0.370nMT: 2°CAssay Description:The SAR (Structure Activity Relationship) for ERK ligands covered by
this invention was interrogated using the TdF (Temperature Dependence
Fluoresc...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 1(Mus musculus (Mouse))
University Of Maryland, Baltimore
US Patent
University Of Maryland, Baltimore
US Patent
Affinity DataKd: 0.150nMT: 2°CAssay Description:The SAR (Structure Activity Relationship) for ERK ligands covered by
this invention was interrogated using the TdF (Temperature Dependence
Fluoresc...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 1(Mus musculus (Mouse))
University Of Maryland, Baltimore
US Patent
University Of Maryland, Baltimore
US Patent
Affinity DataKd: 0.510nMT: 2°CAssay Description:The SAR (Structure Activity Relationship) for ERK ligands covered by
this invention was interrogated using the TdF (Temperature Dependence
Fluoresc...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 1(Mus musculus (Mouse))
University Of Maryland, Baltimore
US Patent
University Of Maryland, Baltimore
US Patent
Affinity DataKd: 0.300nMT: 2°CAssay Description:The SAR (Structure Activity Relationship) for ERK ligands covered by
this invention was interrogated using the TdF (Temperature Dependence
Fluoresc...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 1(Mus musculus (Mouse))
University Of Maryland, Baltimore
US Patent
University Of Maryland, Baltimore
US Patent
Affinity DataKd: 0.25nMT: 2°CAssay Description:The SAR (Structure Activity Relationship) for ERK ligands covered by
this invention was interrogated using the TdF (Temperature Dependence
Fluoresc...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 1(Mus musculus (Mouse))
University Of Maryland, Baltimore
US Patent
University Of Maryland, Baltimore
US Patent
Affinity DataKd: 1.51nMT: 2°CAssay Description:The SAR (Structure Activity Relationship) for ERK ligands covered by
this invention was interrogated using the TdF (Temperature Dependence
Fluoresc...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 1(Mus musculus (Mouse))
University Of Maryland, Baltimore
US Patent
University Of Maryland, Baltimore
US Patent
Affinity DataKd: 1.12nMT: 2°CAssay Description:The SAR (Structure Activity Relationship) for ERK ligands covered by
this invention was interrogated using the TdF (Temperature Dependence
Fluoresc...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 1(Mus musculus (Mouse))
University Of Maryland, Baltimore
US Patent
University Of Maryland, Baltimore
US Patent
Affinity DataKd: 0.470nMT: 2°CAssay Description:The SAR (Structure Activity Relationship) for ERK ligands covered by
this invention was interrogated using the TdF (Temperature Dependence
Fluoresc...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 1(Mus musculus (Mouse))
University Of Maryland, Baltimore
US Patent
University Of Maryland, Baltimore
US Patent
Affinity DataKd: 2.10nMT: 2°CAssay Description:The SAR (Structure Activity Relationship) for ERK ligands covered by
this invention was interrogated using the TdF (Temperature Dependence
Fluoresc...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 1(Mus musculus (Mouse))
University Of Maryland, Baltimore
US Patent
University Of Maryland, Baltimore
US Patent
Affinity DataKd: 0.310nMT: 2°CAssay Description:The SAR (Structure Activity Relationship) for ERK ligands covered by
this invention was interrogated using the TdF (Temperature Dependence
Fluoresc...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 1(Mus musculus (Mouse))
University Of Maryland, Baltimore
US Patent
University Of Maryland, Baltimore
US Patent
Affinity DataKd: 0.150nMT: 2°CAssay Description:The SAR (Structure Activity Relationship) for ERK ligands covered by
this invention was interrogated using the TdF (Temperature Dependence
Fluoresc...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 1(Mus musculus (Mouse))
University Of Maryland, Baltimore
US Patent
University Of Maryland, Baltimore
US Patent
Affinity DataKd: 1.36nMT: 2°CAssay Description:The SAR (Structure Activity Relationship) for ERK ligands covered by
this invention was interrogated using the TdF (Temperature Dependence
Fluoresc...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 1(Mus musculus (Mouse))
University Of Maryland, Baltimore
US Patent
University Of Maryland, Baltimore
US Patent
Affinity DataKd: 1.55nMT: 2°CAssay Description:The SAR (Structure Activity Relationship) for ERK ligands covered by
this invention was interrogated using the TdF (Temperature Dependence
Fluoresc...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 1(Mus musculus (Mouse))
University Of Maryland, Baltimore
US Patent
University Of Maryland, Baltimore
US Patent
Affinity DataKd: 0.130nMT: 2°CAssay Description:The SAR (Structure Activity Relationship) for ERK ligands covered by
this invention was interrogated using the TdF (Temperature Dependence
Fluoresc...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 1(Mus musculus (Mouse))
University Of Maryland, Baltimore
US Patent
University Of Maryland, Baltimore
US Patent
Affinity DataKd: 0.400nMT: 2°CAssay Description:The SAR (Structure Activity Relationship) for ERK ligands covered by
this invention was interrogated using the TdF (Temperature Dependence
Fluoresc...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 1(Mus musculus (Mouse))
University Of Maryland, Baltimore
US Patent
University Of Maryland, Baltimore
US Patent
Affinity DataKd: 0.140nMT: 2°CAssay Description:The SAR (Structure Activity Relationship) for ERK ligands covered by
this invention was interrogated using the TdF (Temperature Dependence
Fluoresc...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 1(Mus musculus (Mouse))
University Of Maryland, Baltimore
US Patent
University Of Maryland, Baltimore
US Patent
Affinity DataKd: 0.0300nMT: 2°CAssay Description:The SAR (Structure Activity Relationship) for ERK ligands covered by
this invention was interrogated using the TdF (Temperature Dependence
Fluoresc...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 1(Mus musculus (Mouse))
University Of Maryland, Baltimore
US Patent
University Of Maryland, Baltimore
US Patent
Affinity DataKd: 0.120nMT: 2°CAssay Description:The SAR (Structure Activity Relationship) for ERK ligands covered by
this invention was interrogated using the TdF (Temperature Dependence
Fluoresc...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 1(Mus musculus (Mouse))
University Of Maryland, Baltimore
US Patent
University Of Maryland, Baltimore
US Patent
Affinity DataKd: 0.0300nMT: 2°CAssay Description:The SAR (Structure Activity Relationship) for ERK ligands covered by
this invention was interrogated using the TdF (Temperature Dependence
Fluoresc...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 1(Mus musculus (Mouse))
University Of Maryland, Baltimore
US Patent
University Of Maryland, Baltimore
US Patent
Affinity DataKd: 0.0600nMT: 2°CAssay Description:The SAR (Structure Activity Relationship) for ERK ligands covered by
this invention was interrogated using the TdF (Temperature Dependence
Fluoresc...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Ambit Biosciences
Curated by PubChem BioAssay
Ambit Biosciences
Curated by PubChem BioAssay
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to ERK2More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Ambit Biosciences
Curated by PubChem BioAssay
Ambit Biosciences
Curated by PubChem BioAssay
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to ERK2More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Ambit Biosciences
Curated by PubChem BioAssay
Ambit Biosciences
Curated by PubChem BioAssay
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for ERK2 kinase domainMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Ambit Biosciences
Curated by PubChem BioAssay
Ambit Biosciences
Curated by PubChem BioAssay
Affinity DataKd: 7.30E+3nMAssay Description:Binding constant for ERK2 kinase domainMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Ambit Biosciences
Curated by PubChem BioAssay
Ambit Biosciences
Curated by PubChem BioAssay
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for ERK2 kinase domainMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Ambit Biosciences
Curated by PubChem BioAssay
Ambit Biosciences
Curated by PubChem BioAssay
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for ERK2 kinase domainMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Ambit Biosciences
Curated by PubChem BioAssay
Ambit Biosciences
Curated by PubChem BioAssay
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for full-length ERK2More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Ambit Biosciences
Curated by PubChem BioAssay
Ambit Biosciences
Curated by PubChem BioAssay
Affinity DataKd: 7.30E+3nMAssay Description:Binding constant for full-length ERK2More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Ambit Biosciences
Curated by PubChem BioAssay
Ambit Biosciences
Curated by PubChem BioAssay
Affinity DataKd: 1.90E+3nMAssay Description:Binding affinity to activated Erk2 (unknown origin) by TdF assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Ambit Biosciences
Curated by PubChem BioAssay
Ambit Biosciences
Curated by PubChem BioAssay
Affinity DataKd: 1.06E+3nMAssay Description:Binding affinity to non-phosphorylated Erk2 (unknown origin) by TdF assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Ambit Biosciences
Curated by PubChem BioAssay
Ambit Biosciences
Curated by PubChem BioAssay
Affinity DataKd: 5.00E+3nMAssay Description:Dissociation constant for ERK2 kinaseMore data for this Ligand-Target Pair