Compile Data Set for Download or QSAR
Report error Found 1177 of ki data for polymerid = 1730,4252,4360,6180,50003845
TargetCathepsin B(Goat)
Kurukshetra University

LigandPNGBDBM120828(N-formyl-5-(-3'-nitrophenyl)-3-phenylpyrazolin...)
Affinity DataKi:  0.0110nM ΔG°:  -65.1kJ/molepH: 6.0 T: 2°CAssay Description:Enzyme was equilibrated in 0.1 M phosphate buffer, pH 6.0 at 37 °C. All compounds were prepared in DMSO. Various concentrations of compounds we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2014
Entry Details Article
PubMed
TargetCathepsin B(Goat)
Kurukshetra University

LigandPNGBDBM50286441(Ac-LLR-CHO | Ac-Leu-Leu-Arg-H | (S)-2-((S)-2-Acety...)
Affinity DataKi:  0.0200nMAssay Description:Competitive inhibition of goat brain cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2015
Entry Details Article
PubMed
TargetCathepsin B(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50167289((1S)-2-cyclohexyl-1-methylethyl 2-cyano-2-methylhy...)
Affinity DataKi:  0.0770nMAssay Description:Inhibition constant against human cathepsin B in fluorescence assay using Cbz-Phe-Arg-AMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin B(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50284944(((S)-1-(S)-Oxiranyl-2-phenyl-ethyl)-carbamic acid ...)
Affinity DataKi:  0.0870nMAssay Description:Kinetic parameter (Ki 1/min) was evaluated for the inactivation of cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetCathepsin B(Bovine)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50053851((3-Methyl-1-{1-[3-(3,4,4a,8a-tetrahydro-2H-quinoli...)
Affinity DataKi:  0.0940nMAssay Description:Inhibition of bovine cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin B(Goat)
Kurukshetra University

LigandPNGBDBM120829(N-formyl-5-(-4'-nitrophenyl)-3-phenylpyrazolin...)
Affinity DataKi:  0.113nM ΔG°:  -59.1kJ/molepH: 6.0 T: 2°CAssay Description:Enzyme was equilibrated in 0.1 M phosphate buffer, pH 6.0 at 37 °C. All compounds were prepared in DMSO. Various concentrations of compounds we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2014
Entry Details Article
PubMed
TargetCathepsin B(Bovine)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50053800((1-{1-Benzyl-2-oxo-2-[3-(3,4,4a,8a-tetrahydro-2H-q...)
Affinity DataKi:  0.140nMAssay Description:Inhibition of bovine cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin B(Goat)
Kurukshetra University

LigandPNGBDBM120827(N-formyl-5-(-2'-nitrophenyl)-3-phenylpyrazolin...)
Affinity DataKi:  0.141nM ΔG°:  -58.5kJ/molepH: 6.0 T: 2°CAssay Description:Enzyme was equilibrated in 0.1 M phosphate buffer, pH 6.0 at 37 °C. All compounds were prepared in DMSO. Various concentrations of compounds we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2014
Entry Details Article
PubMed
TargetCathepsin B(Goat)
Kurukshetra University

LigandPNGBDBM120822(N-formyl-5-(-3'-chlorophenyl)-3-phenylpyrazoli...)
Affinity DataKi:  0.146nM ΔG°:  -58.4kJ/molepH: 6.0 T: 2°CAssay Description:Enzyme was equilibrated in 0.1 M phosphate buffer, pH 6.0 at 37 °C. All compounds were prepared in DMSO. Various concentrations of compounds we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2014
Entry Details Article
PubMed
TargetCathepsin B(Goat)
Kurukshetra University

LigandPNGBDBM120821(N-formyl-5-(-2'-chlorophenyl)-3-phenylpyrazoli...)
Affinity DataKi:  0.180nM ΔG°:  -57.9kJ/molepH: 6.0 T: 2°CAssay Description:Enzyme was equilibrated in 0.1 M phosphate buffer, pH 6.0 at 37 °C. All compounds were prepared in DMSO. Various concentrations of compounds we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2014
Entry Details Article
PubMed
TargetCathepsin B(Goat)
Kurukshetra University

LigandPNGBDBM120823(N-formyl-5-(-4'-chlorophenyl)-3-phenylpyrazoli...)
Affinity DataKi:  0.211nM ΔG°:  -57.4kJ/molepH: 6.0 T: 2°CAssay Description:Enzyme was equilibrated in 0.1 M phosphate buffer, pH 6.0 at 37 °C. All compounds were prepared in DMSO. Various concentrations of compounds we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2014
Entry Details Article
PubMed
TargetCathepsin B(Goat)
Kurukshetra University

LigandPNGBDBM120820(N-formyl-3,5-diphenylpyrazoline (1a))
Affinity DataKi:  0.227nM ΔG°:  -57.3kJ/molepH: 6.0 T: 2°CAssay Description:Enzyme was equilibrated in 0.1 M phosphate buffer, pH 6.0 at 37 °C. All compounds were prepared in DMSO. Various concentrations of compounds we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2014
Entry Details Article
PubMed
TargetCathepsin B(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50167288((1S)-1-benzylpropyl 2-cyano-2-methylhydrazinecarbo...)
Affinity DataKi:  0.25nMAssay Description:Inhibition constant against human cathepsin B in fluorescence assay using Cbz-Phe-Arg-AMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin B(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50335289(N-{4-[5-(2-Thienyl)-1,2,4-oxadiazol-3-yl]benzoyl}-...)
Affinity DataKi:  0.360nMAssay Description:Inhibition of human recombinant cathepsin B after 30 mins by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetCathepsin B(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50335279(N-(Benzyloxycarbonyl)-tyrosyl-methylazalanine-nitr...)
Affinity DataKi:  0.380nMAssay Description:Inhibition of human recombinant cathepsin B after 30 mins by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetCathepsin B(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50030745(CHEMBL3342185 | acs.jmedchem.1c00409_ST.412)
Affinity DataKi:  0.406nMAssay Description:Inhibition of human cathepsin B using Z-Arg-Arg-pNA chromogenic substrate fluorogenic substrate incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMed
TargetCathepsin B(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50304794((S)-benzyl 1-(2-cyano-1,2-dimethylhydrazinyl)-4-me...)
Affinity DataKi:  0.430nMAssay Description:Inhibition of human recombinant cathepsin B after 30 mins by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetCathepsin B(Goat)
Kurukshetra University

LigandPNGBDBM120826(N-formyl-5-(-4'-methoxyphenyl)-3-phenylpyrazol...)
Affinity DataKi:  0.448nM ΔG°:  -55.5kJ/molepH: 6.0 T: 2°CAssay Description:Enzyme was equilibrated in 0.1 M phosphate buffer, pH 6.0 at 37 °C. All compounds were prepared in DMSO. Various concentrations of compounds we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2014
Entry Details Article
PubMed
TargetCathepsin B(Goat)
Kurukshetra University

LigandPNGBDBM120825(N-formyl-5-(-3'-methoxyphenyl)-3-phenylpyrazol...)
Affinity DataKi:  0.455nM ΔG°:  -55.5kJ/molepH: 6.0 T: 2°CAssay Description:Enzyme was equilibrated in 0.1 M phosphate buffer, pH 6.0 at 37 °C. All compounds were prepared in DMSO. Various concentrations of compounds we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2014
Entry Details Article
PubMed
TargetCathepsin B(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50030746(CHEMBL3342184 | acs.jmedchem.1c00409_ST.413)
Affinity DataKi:  0.459nMAssay Description:Inhibition of human cathepsin B using Z-Arg-Arg-pNA chromogenic substrate fluorogenic substrate incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMed
TargetCathepsin B(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50335278(N-(Benzyloxycarbonyl)-cyclohexylalanyl-methylazala...)
Affinity DataKi:  0.480nMAssay Description:Inhibition of human recombinant cathepsin B after 30 mins by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetCathepsin B(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50335280(N-(Benzylcarbamoyl)-leucyl-methylazaalanine-nitril...)
Affinity DataKi:  0.650nMAssay Description:Inhibition of human recombinant cathepsin B after 30 mins by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetCathepsin B(Goat)
Kurukshetra University

LigandPNGBDBM120824(N-formyl-5-(-2'-methoxyphenyl)-3-phenylpyrazol...)
Affinity DataKi:  0.668nM ΔG°:  -54.5kJ/molepH: 6.0 T: 2°CAssay Description:Enzyme was equilibrated in 0.1 M phosphate buffer, pH 6.0 at 37 °C. All compounds were prepared in DMSO. Various concentrations of compounds we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2014
Entry Details Article
PubMed
TargetCathepsin B(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50304793((S)-benzyl 1-(2-cyano-1,2-dimethylhydrazinyl)-1-ox...)
Affinity DataKi:  0.680nMAssay Description:Inhibition of human recombinant cathepsin B after 30 mins by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetCathepsin B(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50510762(CHEMBL4442025)
Affinity DataKi:  0.690nMAssay Description:Inhibition of human liver cathepsin B using Z-Phe-Arg-AMC as substrate incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetCathepsin B(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50335277(N-(Benzyloxycarbonyl)-isoleucyl-methylazalanine-ni...)
Affinity DataKi:  0.880nMAssay Description:Inhibition of human recombinant cathepsin B after 30 mins by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetCathepsin B(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50290289((S)-2-[(S)-2-((S)-2-Acetylamino-4-methyl-pentanoyl...)
Affinity DataKi:  1nMAssay Description:Equilibrium dissociation constant for the inhibition of human cathepsin B was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetCathepsin B(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50167290((1S)-2-cyclohexyl-1-methylethyl 2-cyano-2-isopropy...)
Affinity DataKi:  1.30nMAssay Description:Inhibition constant against human cathepsin B in fluorescence assay using Cbz-Phe-Arg-AMCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin B(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50335281(N-(Phenylcarbamoyl)-leucyl-methylazaalanine-nitril...)
Affinity DataKi:  1.30nMAssay Description:Inhibition of human recombinant cathepsin B after 30 mins by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetCathepsin B(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50335283(N-{4-[5-(2-Thienyl)-1,2,4-oxadiazol-3-yl]benzylcar...)
Affinity DataKi:  1.30nMAssay Description:Inhibition of human recombinant cathepsin B after 30 mins by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetCathepsin B(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50137733((1S,5S,6R)-2-((S)-3,3-Dimethyl-2-{(S)-3-methyl-2-[...)
Affinity DataKi:  1.60nMAssay Description:Inhibitory activity against cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin B(Goat)
Kurukshetra University

LigandPNGBDBM120838(N-benzoyl-5-(-3'-nitrophenyl)-3-phenylpyrazoli...)
Affinity DataKi:  1.95nM ΔG°:  -51.7kJ/molepH: 6.0 T: 2°CAssay Description:Enzyme was equilibrated in 0.1 M phosphate buffer, pH 6.0 at 37 °C. All compounds were prepared in DMSO. Various concentrations of compounds we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2014
Entry Details Article
PubMed
TargetCathepsin B(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM93204(Mercaptomethyl ketone Inhibitor, 53)
Affinity DataKi:  2nMpH: 5.5Assay Description:A fluorometric high-throughput assay for activity against cathepsin B was performed in 96-well microtiter plates. The assay were performed in Dynate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2013
Entry Details Article
PubMed
TargetCathepsin B(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50374367(CHEMBL271004)
Affinity DataKi:  2nMAssay Description:Inhibition of human liver cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCathepsin B(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50410979(CHEMBL207347)
Affinity DataKi:  2nMAssay Description:Inhibition of human cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetCathepsin B(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50510761(CHEMBL4440655)
Affinity DataKi:  2nMAssay Description:Inhibition of human liver cathepsin B using Z-Phe-Arg-AMC as substrate incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetCathepsin B(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50230555(CHEMBL5267078)
Affinity DataKi:  2nMAssay Description:Binding affinity to Cathepsin B (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details Article
PubMed
TargetCathepsin B(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50335284(N-[4-(5-Methyl-1,2,4-oxadiazol-3-yl)phenylcarbamoy...)
Affinity DataKi:  2.40nMAssay Description:Inhibition of human recombinant cathepsin B after 30 mins by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetCathepsin B(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50335285(N-{4-[5-(2-Thienyl)-1,2,4-oxadiazol-3-yl]phenylcar...)
Affinity DataKi:  2.40nMAssay Description:Inhibition of human recombinant cathepsin B after 30 mins by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetCathepsin B(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50335282(N-[4-(5-Methyl-1,2,4-oxadiazol-3-yl)benzylcarbamoy...)
Affinity DataKi:  2.80nMAssay Description:Inhibition of human recombinant cathepsin B after 30 mins by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetCathepsin B(Goat)
Kurukshetra University

LigandPNGBDBM120839(N-benzoyl-5-(-4'-nitrophenyl)-3-phenylpyrazoli...)
Affinity DataKi:  2.87nM ΔG°:  -50.7kJ/molepH: 6.0 T: 2°CAssay Description:Enzyme was equilibrated in 0.1 M phosphate buffer, pH 6.0 at 37 °C. All compounds were prepared in DMSO. Various concentrations of compounds we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2014
Entry Details Article
PubMed
TargetCathepsin B(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM16510(HO-tES-Leu-NH-CH2-CH2CH(CH3)2 | (2S,3S)-3-[[(2S)-4...)
Affinity DataKi:  3.36nMAssay Description:Inhibition of cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetCathepsin B(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50030747(CHEMBL3342183)
Affinity DataKi:  3.60nMAssay Description:Inhibition of human cathepsin B using Z-Arg-Arg-pNA chromogenic substrate fluorogenic substrate incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMed
TargetCathepsin B(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50137736((1S,5S,6R)-2-((S)-3,3-Dimethyl-2-{(S)-3-methyl-2-[...)
Affinity DataKi:  3.70nMAssay Description:Inhibitory activity against cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin B(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50137720((1S,5S,6R)-2-((S)-3-Methyl-2-{(S)-3-methyl-2-[(pyr...)
Affinity DataKi:  4nMAssay Description:Inhibitory activity against cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin B(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50065404((R)-N-((S)-5-Benzenesulfonylamino-1-formyl-pentyl)...)
Affinity DataKi:  4nMAssay Description:Inhibitory activity against cathepsin B receptor in human liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2012
Entry Details Article
PubMed
TargetCathepsin B(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50335276(N-(Benzyloxycarbonyl)-valyl-methylazalanine-nitril...)
Affinity DataKi:  4.30nMAssay Description:Inhibition of human recombinant cathepsin B after 30 mins by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetCathepsin B(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50053813((1-{1-Benzyl-2-oxo-2-[3-(3,4,4a,8a-tetrahydro-1H-i...)
Affinity DataKi:  4.5nMAssay Description:Inhibition of human cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin B(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM93203(Mercaptomethyl ketone Inhibitor, 52)
Affinity DataKi:  4.70nMpH: 5.5Assay Description:A fluorometric high-throughput assay for activity against cathepsin B was performed in 96-well microtiter plates. The assay were performed in Dynate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2013
Entry Details Article
PubMed
TargetCathepsin B(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50137730((1S,5S,6R)-2-((S)-3,3-Dimethyl-2-{(S)-3-methyl-2-[...)
Affinity DataKi:  5nMAssay Description:Inhibitory activity against cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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