Compile Data Set for Download or QSAR
maximum 50k data
Found 8 of ki data for polymerid = 2234
TargetNitric oxide synthase, brain [D597N](Rattus norvegicus (rat))
University Of California Irvine

LigandPNGBDBM190667(US10759791, Compound 14j | nNOS inhibitor, 5)
Affinity DataKi:  46.7nM ΔG°:  -43.5kJ/molepH: 7.4 T: 2°CAssay Description:The assay was performed at 37 °C in HEPES buffer (100 mM, with 10% glycerol, pH 7.4) in the presence of 10 uM L-arginine. Also included were 100 ...More data for this Ligand-Target Pair
TargetNitric oxide synthase, brain [D597N](Rattus norvegicus (rat))
University Of California Irvine

LigandPNGBDBM190668(US10759791, Compound 14k | nNOS inhibitor, 6)
Affinity DataKi:  97.5nM ΔG°:  -41.6kJ/molepH: 7.4 T: 2°CAssay Description:The assay was performed at 37 °C in HEPES buffer (100 mM, with 10% glycerol, pH 7.4) in the presence of 10 uM L-arginine. Also included were 100 ...More data for this Ligand-Target Pair
TargetNitric oxide synthase, brain [D597N](Rattus norvegicus (rat))
University Of California Irvine

LigandPNGBDBM152712(4-methyl-6-[2-(5-{methyl[2-(methylamino)ethyl]amin...)
Affinity DataKi:  139nM ΔG°:  -40.7kJ/molepH: 7.4 T: 2°CAssay Description:The assay was performed at 37 °C in HEPES buffer (100 mM, with 10% glycerol, pH 7.4) in the presence of 10 uM L-arginine. Also included were 100 ...More data for this Ligand-Target Pair
TargetNitric oxide synthase, brain [D597N](Rattus norvegicus (rat))
University Of California Irvine

LigandPNGBDBM190666(US10759791, Compound 14h | nNOS inhibitor, 4)
Affinity DataKi:  641nM ΔG°:  -36.8kJ/molepH: 7.4 T: 2°CAssay Description:The assay was performed at 37 °C in HEPES buffer (100 mM, with 10% glycerol, pH 7.4) in the presence of 10 uM L-arginine. Also included were 100 ...More data for this Ligand-Target Pair
TargetNitric oxide synthase, brain [D597N](Rattus norvegicus (rat))
University Of California Irvine

LigandPNGBDBM190665(US10759791, Compound 14g | nNOS inhibitor, 3)
Affinity DataKi:  748nM ΔG°:  -36.4kJ/molepH: 7.4 T: 2°CAssay Description:The assay was performed at 37 °C in HEPES buffer (100 mM, with 10% glycerol, pH 7.4) in the presence of 10 uM L-arginine. Also included were 100 ...More data for this Ligand-Target Pair
TargetNitric oxide synthase, brain [D597N](Rattus norvegicus (rat))
University Of California Irvine

LigandPNGBDBM21961((2S,4R)-4-[(2S)-2-amino-5-(1-nitrocarbamimidamido)...)
Affinity DataKi:  2.10E+4nM ΔG°:  -27.1kJ/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
TargetNitric oxide synthase, brain [D597N](Rattus norvegicus (rat))
University Of California Irvine

LigandPNGBDBM21960(3-[(4S)-4-amino-5-[(2-aminoethyl)amino]pentyl]-1-n...)
Affinity DataKi:  3.40E+4nM ΔG°:  -25.9kJ/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
TargetNitric oxide synthase, brain [D597N](Rattus norvegicus (rat))
University Of California Irvine

LigandPNGBDBM22030((2S)-2-amino-N-[(1S)-3-amino-1-(aminocarbonyl)prop...)
Affinity DataKi:  6.70E+4nM ΔG°:  -24.2kJ/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair