Compile Data Set for Download or QSAR
maximum 50k data
Found 3736 of ki data for polymerid = 2253
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM364427(US10913711, Compound 10a | US11555013, Compound 10...)
Affinity DataKi: >0nMAssay Description:Serotonin Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, midbrain ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50109062(3-{1-[2-(2,3-Dihydro-benzo[1,4]dioxin-5-yloxy)-eth...)
Affinity DataKi:  0.0100nMAssay Description:Affinity of the compound for RB Serotonin transporter was determined in vitro by incubating compoundMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50110577(2-(2-((dimethylamino)methyl)phenylthio)-5-iodoanil...)
Affinity DataKi:  0.0130nMAssay Description:Displacement of [3H]citalopram from rat cortical serotonin transporter (SERT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50110577(2-(2-((dimethylamino)methyl)phenylthio)-5-iodoanil...)
Affinity DataKi:  0.0130nMAssay Description:In vitro binding affinity of the compound in LLC-PK1 cells by SERT binding assay by using [125I]-IDAM as a radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50160893(8-Methyl-3-(4-thiophen-3-yl-phenyl)-8-aza-bicyclo[...)
Affinity DataKi:  0.0170nMAssay Description:Displacement of [3H]paroxetine from serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM22416((3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-f...)
Affinity DataKi:  0.0190nMMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50109058(1H-4-indolyl 2-[4-(1H-3-indolyl)-1,2,3,6-tetrahydr...)
Affinity DataKi:  0.0300nMAssay Description:Affinity of the compound for RB Serotonin transporter was determined in vitro by incubating compoundMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50110578(4-Chloro-6-nitro-2-piperazin-1-yl-quinoline | CHEM...)
Affinity DataKi:  0.0300nMAssay Description:Displacement of [3H]citalopram from rat cortical serotonin transporter (SERT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM82217(CHEMBL284994 | CP-52003 | SERTRALINE | [4-(3,4-Dic...)
Affinity DataKi:  0.0400nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM22416((3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-f...)
Affinity DataKi:  0.0400nMMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM82217(CHEMBL284994 | CP-52003 | SERTRALINE | [4-(3,4-Dic...)
Affinity DataKi:  0.0470nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50331515(CHEMBL1708 | PAROXETINE | Paroxetine hydrochloride...)
Affinity DataKi:  0.0500nMAssay Description:Displacement of [3H]citalopram from serotonin transporter in Sprague-Dawley rat brain after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM22416((3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-f...)
Affinity DataKi:  0.0500nMMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50119550(5-Chloro-2-(2-dimethylaminomethyl-phenylsulfanyl)-...)
Affinity DataKi:  0.0500nMAssay Description:In vitro binding affinity of the compound in LLC-PK1 cells by SERT binding assay by using [125I]-IDAM as a radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50127388(3-(4-Isopropenyl-phenyl)-8-aza-bicyclo[3.2.1]octan...)
Affinity DataKi:  0.0550nMAssay Description:Inhibition of [3H]paroxetine binding at serotonin transporter was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50111036(Benzoic acid 9-(3-chloro-4-iodo-benzylidene)-7-aza...)
Affinity DataKi:  0.0600nMAssay Description:Inhibition of [3H]5-HT reuptake at serotonin transporter in rat mid brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50111036(Benzoic acid 9-(3-chloro-4-iodo-benzylidene)-7-aza...)
Affinity DataKi:  0.0600nMAssay Description:Inhibition of high affinity re-uptake of [3H]5-HT (serotonin) into nerve ending synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50106857(3-(4-Iodo-phenyl)-8-aza-bicyclo[3.2.1]octane-2-car...)
Affinity DataKi:  0.0600nMAssay Description:Ability to displace [3H]- paroxetine from Serotonin transporter in rat cerebral cortical homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50303312(3-alpha-(4-Dichlorophenyl)methoxy-3-beta-phenyl-no...)
Affinity DataKi:  0.0610nMAssay Description:Displacement of [3H]citalopram from SERT in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50106857(3-(4-Iodo-phenyl)-8-aza-bicyclo[3.2.1]octane-2-car...)
Affinity DataKi:  0.0620nMAssay Description:Binding affinity to serotonin transporter (SERT) in rat forebrain tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50127395(3-(4-Ethyl-3-iodo-phenyl)-8-aza-bicyclo[3.2.1]octa...)
Affinity DataKi:  0.0630nMAssay Description:Inhibition of [3H]paroxetine binding at serotonin transporter was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50130172(1-(3-Benzo[b]thiophen-2-yl-8-aza-bicyclo[3.2.1]oct...)
Affinity DataKi:  0.0700nMAssay Description:In vitro affinity of the compound at the 5-HT reuptake site using [3H]-paroxetine as radioligand in rat frontal cortex membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50150101(CHEMBL419240 | [2-(2,3-Dihydro-benzo[1,4]dioxin-5-...)
Affinity DataKi:  0.0800nMAssay Description:Binding affinity against serotonin transporter in rat cortical tissues using radioligand [3H]-paroxetineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50094929(2-(2-Methyl-piperazin-1-yl)-6-nitro-quinoline | CH...)
Affinity DataKi:  0.0810nMAssay Description:In vitro radioligand [3H]-paroxetine from rat cortical Serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50073436((2-(2-((dimethylamino)methyl)phenylthio)-5-iodophe...)
Affinity DataKi:  0.0970nMAssay Description:In vitro binding affinity of the compound in LLC-PK1 cells by SERT binding assay by using [125I]-IDAM as a radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50111035(Benzoic acid 9-(4-iodo-benzylidene)-7-aza-tricyclo...)
Affinity DataKi:  0.100nMAssay Description:Inhibition of [3H]5-HT reuptake at serotonin transporter in rat mid brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50112273(Benzoic acid 9-naphthalen-2-ylmethylene-7-aza-tric...)
Affinity DataKi:  0.100nMAssay Description:Inhibition of high affinity re-uptake of [3H]5-HT (serotonin) into nerve ending synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50111035(Benzoic acid 9-(4-iodo-benzylidene)-7-aza-tricyclo...)
Affinity DataKi:  0.100nMAssay Description:Inhibition of high affinity re-uptake of [3H]5-HT (serotonin) into nerve ending synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50102006(3-[4-(6-Methoxy-3,4-dihydro-1H-isoquinolin-2-yl)-c...)
Affinity DataKi:  0.100nMAssay Description:In vitro for its binding affinity for serotonin transporter RB5-HT-T in rat cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50073436((2-(2-((dimethylamino)methyl)phenylthio)-5-iodophe...)
Affinity DataKi:  0.100nMAssay Description:Displacement of [125I]IPT from SERT in rat brain cortex membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM82071(CAS_93413-69-5 | CAS_99300-78-4 | NSC_62923 | VENL...)
Affinity DataKi:  0.100nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50303314(3-alpha-(4-Chlorophenyl)methoxy-3-beta-(4-chloroph...)
Affinity DataKi:  0.100nMAssay Description:Displacement of [3H]citalopram from SERT in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50145347(1-(2-(4-(6-fluoro-1H-indol-3-yl)-5,6-dihydropyridi...)
Affinity DataKi:  0.110nMAssay Description:In vitro binding affinity towards serotonin transporter using [3H]citalopram as radioligand in rat cerebral cortex membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50051751(1-[3-(4-Isopropenyl-phenyl)-8-aza-bicyclo[3.2.1]oc...)
Affinity DataKi:  0.110nMAssay Description:Displacement of [3H]-paroxetine from Serotonin transporter of rat frontal cortex membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50160892(3-(4-Thiophen-2-yl-phenyl)-8-aza-bicyclo[3.2.1]oct...)
Affinity DataKi:  0.110nMAssay Description:Displacement of [3H]paroxetine from serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50048558(8-(3-Fluoro-propyl)-3-(4-iodo-phenyl)-8-aza-bicycl...)
Affinity DataKi:  0.110nMAssay Description:In vitro binding affinity towards serotonin transporter in rat cerebral cortical homogenates by [3H]paroxetine displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50063266(6-Nitro-2-piperazin-1-yl-quinoline | 6-nitroquipaz...)
Affinity DataKi:  0.120nMAssay Description:Ability to displace [3H]paroxetine bound to Serotonin transporter receptor in rat forebrainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50063266(6-Nitro-2-piperazin-1-yl-quinoline | 6-nitroquipaz...)
Affinity DataKi:  0.120nMAssay Description:Binding affinity towards Serotonin transporter was determined in rat forebrain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50041293(1-(8-Methyl-3-naphthalen-2-yl-8-aza-bicyclo[3.2.1]...)
Affinity DataKi:  0.121nMAssay Description:Inhibition of [3H]paroxetine binding to serotonin transport sites in rat frontal cortex membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50021226(CHEMBL296602 | Indatraline | [3-(3,4-Dichloro-phen...)
Affinity DataKi:  0.130nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50111887(1-{3-[4-((Z)-2-Iodo-propenyl)-phenyl]-8-aza-bicycl...)
Affinity DataKi:  0.130nMAssay Description:Tested for the ability to displace [3H]- paroxetine binding in rat frontal cortex membrane against Serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50048561(8-(2-Fluoro-ethyl)-3-(4-iodo-phenyl)-8-aza-bicyclo...)
Affinity DataKi:  0.140nMAssay Description:In vitro binding affinity towards serotonin transporter in rat cerebral cortical homogenates by [3H]paroxetine displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM77970(3-(2-chloranyl-5,6-dihydrobenzo[b][1]benzazepin-11...)
Affinity DataKi:  0.140nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM77970(3-(2-chloranyl-5,6-dihydrobenzo[b][1]benzazepin-11...)
Affinity DataKi:  0.140nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50153628(4-[3-(3-Naphthalen-2-yl-8-aza-bicyclo[3.2.1]oct-2-...)
Affinity DataKi:  0.140nMAssay Description:In vitro binding affinity for serotonin transporter More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50160894(8-Methyl-3-(4-thiophen-2-yl-phenyl)-8-aza-bicyclo[...)
Affinity DataKi:  0.150nMAssay Description:Displacement of [3H]paroxetine from serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50109057(3-{1-[2-(2,3-Dihydro-benzo[1,4]dioxin-5-yloxy)-eth...)
Affinity DataKi:  0.150nMAssay Description:Affinity of the compound for RB Serotonin transporter was determined in vitro by incubating compoundMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50175644(CHEMBL200044 | methyl 3-(4-(furan-2-yl)phenyl)-8-a...)
Affinity DataKi:  0.150nMAssay Description:Displacement of [3H]paroxetine from SERT in rat frontoparietal cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50063266(6-Nitro-2-piperazin-1-yl-quinoline | 6-nitroquipaz...)
Affinity DataKi:  0.163nMAssay Description:In vitro radioligand [3H]-paroxetine from rat cortical Serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50063266(6-Nitro-2-piperazin-1-yl-quinoline | 6-nitroquipaz...)
Affinity DataKi:  0.163nMAssay Description:In vitro radioligand [3H]-paroxetine from rat cortical Serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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