Compile Data Set for Download or QSAR
Report error Found 35 of ki data for polymerid = 3022
TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50330426BDBM50330426(5-Fluoro-4-hydroxybiphenyl-3-carboxylic acid | CHE...)
Affinity DataKi:  1.5nMAssay Description:Inhibition of human AKR1C2 dehydrogenase activity by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50330431BDBM50330431(4'-Butyl-5-chloro-4-hydroxybiphenyl-3-carboxylic a...)
Affinity DataKi:  14nMAssay Description:Inhibition of human AKR1C2 dehydrogenase activity by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50330428BDBM50330428(5-Chloro-4-hydroxy-3'-methylbiphenyl-3-carboxylic ...)
Affinity DataKi:  17nMAssay Description:Inhibition of human AKR1C2 dehydrogenase activity by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50330427BDBM50330427(5-Chloro-4-hydroxybiphenyl-3-carboxylic acid | CHE...)
Affinity DataKi:  21nMAssay Description:Inhibition of human AKR1C2 dehydrogenase activity by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50330424BDBM50330424(5-Chloro-4-hydroxy-4'-(trifluoromethoxy)biphenyl-3...)
Affinity DataKi:  26nMAssay Description:Inhibition of human AKR1C2 dehydrogenase activity by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50330432BDBM50330432(5-Chloro-4-hydroxy-4'-isobutylbiphenyl-3-carboxyli...)
Affinity DataKi:  29nMAssay Description:Inhibition of human AKR1C2 dehydrogenase activity by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50330429BDBM50330429(5-Chloro-4-hydroxy-4'-methylbiphenyl-3-carboxylic ...)
Affinity DataKi:  63nMAssay Description:Inhibition of human AKR1C2 dehydrogenase activity by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 26269BDBM26269(3,5-dichloro-2-hydroxybenzoic acid | CHEMBL449129 ...)
Affinity DataKi:  70nM ΔG°:  -40.8kJ/molepH: 7.4 T: 2°CAssay Description:The activity was assayed by measuring the rate of change in NADPH fluorescence (at 455 nm with an excitation wavelength of 340 nm) at 298 K. When the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 26269BDBM26269(3,5-dichloro-2-hydroxybenzoic acid | CHEMBL449129 ...)
Affinity DataKi:  70nMAssay Description:Inhibition of human AKR1C2 dehydrogenase activity by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50249792BDBM50249792(3,5-Dibromosalicylic acid | CHEMBL447448)
Affinity DataKi:  82nMAssay Description:Inhibition of human recombinant type 3 3-alpha-HSD expressed in Escherichia coli JM109More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50219490BDBM50219490(5-bromo-4-hydroxybiphenyl-3-carboxylic acid | 3-Br...)
Affinity DataKi:  87nMAssay Description:Inhibition of human AKR1C2 dehydrogenase activity by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50219490BDBM50219490(5-bromo-4-hydroxybiphenyl-3-carboxylic acid | 3-Br...)
Affinity DataKi:  87nMAssay Description:Inhibition of human recombinant type 3 3-alpha-HSD expressed in Escherichia coli JM109More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50330425BDBM50330425(3-chloro-2-hydroxy-5-(phenylethynyl)benzoic acid |...)
Affinity DataKi:  168nMAssay Description:Inhibition of human AKR1C2 dehydrogenase activity by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50134036BDBM50134036(cid_4044 | mefanamic acid | CHEMBL686 | CI-473 | C...)
Affinity DataKi:  220nMAssay Description:Inhibition of human recombinant AKR1C2 assessed as 1-acenaphthenol oxidation by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50330423BDBM50330423(4'-tert-Butyl-5-chloro-4-hydroxybiphenyl-3-carboxy...)
Affinity DataKi:  470nMAssay Description:Inhibition of human AKR1C2 dehydrogenase activity by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 220117BDBM220117(US9271961, 4-Carboxy-2',4'-dinitrodiphenyl...)
Affinity DataKi:  1.32E+3nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50240769BDBM50240769(5-Bromo-2-hydroxy-biphenyl-3-carboxylic acid | 3-P...)
Affinity DataKi:  1.97E+3nMAssay Description:Inhibition of human recombinant type 3 3-alpha-HSD expressed in Escherichia coli JM109More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50330430BDBM50330430(5-Chloro-4-hydroxy-4'-(1-methoxyethyl)biphenyl-3-c...)
Affinity DataKi:  3.00E+3nMAssay Description:Inhibition of human AKR1C2 dehydrogenase activity by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2011
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 220121BDBM220121(US9271961, Cloxazolam)
Affinity DataKi: >1.00E+4nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50396691BDBM50396691(CHEMBL449572 | US9271961, Jasmonic acid)
Affinity DataKi:  1.50E+4nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50396691BDBM50396691(CHEMBL449572 | US9271961, Jasmonic acid)
Affinity DataKi:  1.80E+4nMAssay Description:Inhibition of human recombinant AKR1C2 expressed in Escherichia coli BL21(DE3) using phenanthrenequinone as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50396743BDBM50396743(CHEMBL2172255)
Affinity DataKi:  1.82E+4nMAssay Description:Inhibition of human recombinant AKR1C2 assessed as 1-acenaphthenol oxidation by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50396731BDBM50396731(CHEMBL2172254)
Affinity DataKi:  2.13E+4nMAssay Description:Inhibition of human recombinant AKR1C2 assessed as 1-acenaphthenol oxidation by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 34643BDBM34643(3-(3-hydroxy-3-oxopropylamino)naphthalene-2-carbox...)
Affinity DataKi:  3.30E+4nMAssay Description:Inhibition of human recombinant AKR1C2 assessed as 1-acenaphthenol oxidation by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50396733BDBM50396733(CHEMBL2172251)
Affinity DataKi:  4.00E+4nMAssay Description:Inhibition of human recombinant AKR1C2 assessed as 1-acenaphthenol oxidation by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50396748BDBM50396748(CHEMBL366350)
Affinity DataKi:  4.62E+4nMAssay Description:Competitive inhibition of human recombinant AKR1C2 assessed as S-tetralol oxidation by Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50396730BDBM50396730(CHEMBL1328030)
Affinity DataKi:  5.73E+4nMAssay Description:Inhibition of human recombinant AKR1C2 assessed as 1-acenaphthenol oxidation by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50396739BDBM50396739(CHEMBL2172243)
Affinity DataKi:  5.80E+4nMAssay Description:Inhibition of human recombinant AKR1C2 assessed as 1-acenaphthenol oxidation by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50396742BDBM50396742(CHEMBL1373742)
Affinity DataKi:  9.00E+4nMAssay Description:Inhibition of human recombinant AKR1C2 assessed as 1-acenaphthenol oxidation by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 220116BDBM220116(US9271961, CBM)
Affinity DataKi: >1.00E+5nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent

TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 17638BDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataKi: >1.00E+5nMAssay Description:Compounds may be evaluated as selective reversible inhibitors of AKR1C3 by screening them against homogeneous recombinant AKR1C1-AKR1C4 expressed in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2017
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50396749BDBM50396749(CHEMBL2172258)
Affinity DataKi:  1.03E+5nMAssay Description:Competitive inhibition of human recombinant AKR1C2 assessed as S-tetralol oxidation by Cheng-Prusoff equation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50396734BDBM50396734(CHEMBL1896308)
Affinity DataKi:  1.19E+5nMAssay Description:Inhibition of human recombinant AKR1C2 assessed as 1-acenaphthenol oxidation by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50396732BDBM50396732(CHEMBL2172252)
Affinity DataKi:  1.21E+5nMAssay Description:Inhibition of human recombinant AKR1C2 assessed as 1-acenaphthenol oxidation by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50396729BDBM50396729(CHEMBL1414132)
Affinity DataKi:  1.37E+5nMAssay Description:Inhibition of human recombinant AKR1C2 assessed as 1-acenaphthenol oxidation by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed