Compile Data Set for Download or QSAR
Report error Found 224 of ki data for polymerid = 362,49000917
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Rat)
University of Tennessee

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 14775BDBM14775(3-(cyclopentyloxy)-N-(3,5-dichloropyridin-4-yl)-4-...)
Affinity DataKi:  0.0400nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 14774BDBM14774(DAXAS | 3-(cyclopropylmethoxy)-N-(3,5-dichloropyri...)
Affinity DataKi:  0.398nMAssay Description:Inhibition of full length recombinant human PDE4B1 expressed in Sf21 insect cells using cAMP as substrate by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50427452BDBM50427452(CHEMBL2326941)
Affinity DataKi:  0.631nMAssay Description:Inhibition of full length recombinant human PDE4B1 expressed in Sf21 insect cells using cAMP as substrate by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Rat)
University of Tennessee

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 14774BDBM14774(DAXAS | 3-(cyclopropylmethoxy)-N-(3,5-dichloropyri...)
Affinity DataKi:  2.40nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Rat)
University of Tennessee

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 14774BDBM14774(DAXAS | 3-(cyclopropylmethoxy)-N-(3,5-dichloropyri...)
In Depth
Date in BDB:
5/25/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 14361BDBM14361(Adeo | 4-(3-cyclopentyloxy-4-methoxy-phenyl)pyrrol...)
Affinity DataKi:  5nMAssay Description:Binding affinity to human recombinant full length PDE4BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 14381BDBM14381(4-{2-[6-Amino-3-(3-cyclopentyloxy-4-methoxy-benzyl...)
Affinity DataKi:  5.20nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2007
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314557BDBM50314557((4-(3-(4-(3-nitrophenyl)pyridazino[4,5-b]indolizin...)
Affinity DataKi:  5.60nMAssay Description:Displacement of [methyl-3H]rolipram from PDE4B3 expressed in CHO cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 14379BDBM14379(3-(3-Cyclopentyloxy-4-methoxy-benzyl)-8-[1-(4-tert...)
Affinity DataKi:  5.80nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2007
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 14382BDBM14382(4-{2-[6-Amino-3-(3-cyclopentyloxy-4-methoxy-benzyl...)
Affinity DataKi:  7.60nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2007
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 14365BDBM14365(8-[2-(benzyloxy)propan-2-yl]-3-{[3-(cyclopentyloxy...)
Affinity DataKi:  8.90nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2007
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Rat)
University of Tennessee

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 14775BDBM14775(3-(cyclopentyloxy)-N-(3,5-dichloropyridin-4-yl)-4-...)
In Depth
Date in BDB:
5/25/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 14386BDBM14386(3-{[3-(cyclopentyloxy)-4-methoxyphenyl]methyl}-8-[...)
Affinity DataKi:  9.5nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2007
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 14378BDBM14378(3-{[3-(cyclopentyloxy)-4-methoxyphenyl]methyl}-8-{...)
Affinity DataKi:  9.70nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2007
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 14369BDBM14369(3-(3-Cyclopentyloxy-4-methoxy-benzyl)-8-[1-(4-meth...)
Affinity DataKi:  9.80nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2007
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 14368BDBM14368(3-{[3-(cyclopentyloxy)-4-methoxyphenyl]methyl}-8-{...)
Affinity DataKi:  10.3nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2007
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 14366BDBM14366(3-(3-Cyclopentyloxy-4-methoxy-benzyl)-8-[1-(2-meth...)
Affinity DataKi:  11nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2007
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 14370BDBM14370(8-{1-[(4-Chlorobenzyl)oxy]-1-methyl-ethyl}-3-[3-cy...)
Affinity DataKi:  11nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2007
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 14372BDBM14372(3-(3-Cyclopentyloxy-4-methoxy-benzyl)-8-[1-(3-fluo...)
Affinity DataKi:  11.6nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2007
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 14367BDBM14367(3-{[3-(cyclopentyloxy)-4-methoxyphenyl]methyl}-8-{...)
Affinity DataKi:  13nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2007
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Rat)
University of Tennessee

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 14361BDBM14361(Adeo | 4-(3-cyclopentyloxy-4-methoxy-phenyl)pyrrol...)
Affinity DataKi:  16.6nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 14375BDBM14375(3-(3-Cyclopentyloxy-4-methoxy-benzyl)-8-[1-(3,4-di...)
Affinity DataKi:  17.3nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2007
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 14371BDBM14371(3-{[3-(cyclopentyloxy)-4-methoxyphenyl]methyl}-8-{...)
Affinity DataKi:  18.9nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2007
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 14376BDBM14376(3-(3-Cyclopentyloxy-4-methoxy-benzyl)-8-[1-(3,4-me...)
Affinity DataKi:  21.4nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2007
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 14374BDBM14374((2E)-but-2-enedioic acid; 3-{[3-(cyclopentyloxy)-4...)
Affinity DataKi:  21.9nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2007
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 14380BDBM14380(3-{[3-(cyclopentyloxy)-4-methoxyphenyl]methyl}-8-(...)
Affinity DataKi:  26.6nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2007
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50029954BDBM50029954((7R,7aS)-7-(3-Cyclopentyloxy-4-methoxy-phenyl)-hex...)
Affinity DataKi:  27nMAssay Description:Inhibition of human Phosphodiesterase 4BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50048248BDBM50048248(methyl 3-acetyl-4-(3-cyclopentyloxy-4-methoxypheny...)
Affinity DataKi:  30nMAssay Description:Ability to inhibit the catalytic activity of human Phosphodiesterase 4B (PDE IVB)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50285059BDBM50285059(1-(tert-butyl) 3-methyl 4-(3-cyclopentyloxy-4-meth...)
Affinity DataKi:  30nMAssay Description:Ability to inhibit the catalytic activity of human Phosphodiesterase 4B (PDE IVB)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50470745BDBM50470745(CHEMBL286840)
Affinity DataKi:  30nMAssay Description:Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50453147BDBM50453147(CHEMBL4202704)
Affinity DataKi:  32nMAssay Description:Inhibition of full length recombinant human PDE4B1 expressed in Sf21 insect cells using cAMP as substrate by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 14384BDBM14384(3-{[3-(cyclopentyloxy)-4-methoxyphenyl]methyl}-8-(...)
Affinity DataKi:  33nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2007
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50470752BDBM50470752(CHEMBL38328)
Affinity DataKi:  34nMAssay Description:Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Rat)
University of Tennessee

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 86218BDBM86218(NSC_0 | CAS_0 | Desmethylpiclamilas)
Affinity DataKi:  34.8nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2012
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50285045BDBM50285045(1-isopropyl 3-methyl 4-(3-cyclopentyloxy-4-methoxy...)
Affinity DataKi:  40nMAssay Description:Ability to inhibit the catalytic activity of human Phosphodiesterase 4B (PDE IVB)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50314558BDBM50314558((4-(3-(4-phenylpyridazino[4,5-b]indolizin-1-ylamin...)
Affinity DataKi:  41nMAssay Description:Displacement of [methyl-3H]rolipram from PDE4B3 expressed in CHO cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 14373BDBM14373(3-(3-Cyclopentyloxy-4-methoxy-benzyl)-8-[1-(3,4-di...)
Affinity DataKi:  42.8nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2007
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50470756BDBM50470756(CHEMBL37453)
Affinity DataKi:  46nMAssay Description:Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 14385BDBM14385(3-{[3-(cyclopentyloxy)-4-methoxyphenyl]methyl}-8-[...)
Affinity DataKi:  46.9nMAssay Description:PDE4 enzyme activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using SPA kit. [3H]-AMP was captured by the SPA beads, and qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2007
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50285042BDBM50285042(tert-butyl 3-(3-cyclopentyloxy-4-methoxyphenyl)-4-...)
Affinity DataKi:  50nMAssay Description:Ability to inhibit the catalytic activity of human Phosphodiesterase 4B (PDE IVB)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50285038BDBM50285038(1-benzyl 3-methyl 4-(3-cyclopentyloxy-4-methoxyphe...)
Affinity DataKi:  50nMAssay Description:Ability to inhibit the catalytic activity of human Phosphodiesterase 4B (PDE IVB)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50470750BDBM50470750(CHEMBL286291)
Affinity DataKi:  56nMAssay Description:Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50470731BDBM50470731(CHEMBL146946)
Affinity DataKi:  59nMAssay Description:Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50470736BDBM50470736(CHEMBL37029)
Affinity DataKi:  60nMAssay Description:Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50285050BDBM50285050(methyl 3-(3-cyclopentyloxy-4-methoxyphenyl)-4-nitr...)
Affinity DataKi:  60nMAssay Description:Ability to inhibit the catalytic activity of human Phosphodiesterase 4B (PDE IVB)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50029955BDBM50029955((7R,7aR)-7-(3-Cyclopentyloxy-4-methoxy-phenyl)-hex...)
Affinity DataKi:  63nMAssay Description:Inhibition of human Phosphodiesterase 4BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50470740BDBM50470740(CHEMBL264851)
Affinity DataKi:  65nMAssay Description:Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50470754BDBM50470754(CHEMBL288928)
Affinity DataKi:  68nMAssay Description:Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50029951BDBM50029951((7R,7aS)-7-(3-Cyclopentyloxy-4-methoxy-phenyl)-tet...)
Affinity DataKi:  70nMAssay Description:Inhibition of human Phosphodiesterase 4BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50470743BDBM50470743(CHEMBL422578)
Affinity DataKi:  71nMAssay Description:Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
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