Compile Data Set for Download or QSAR
maximum 50k data
Found 1505 of ki data for polymerid = 3744,3987,7709,8553
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM209097(US9266877, 43)
Affinity DataKi:  0.00800nMAssay Description:Inhibition of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide probe binding to BCL-xl (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50030752(CHEMBL3342333)
Affinity DataKi:  0.0100nMAssay Description:Inhibition of BCL-XL (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50030754(CHEMBL3342332)
Affinity DataKi: <0.0100nMAssay Description:Inhibition of BCL-XL (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50030757(CHEMBL3342196)
Affinity DataKi: <0.0100nMAssay Description:Inhibition of BCL-XL (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50030758(CHEMBL3342195)
Affinity DataKi: <0.0100nMAssay Description:Inhibition of BCL-XL (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50561528(CHEMBL4762875)
Affinity DataKi: <0.0100nMAssay Description:Inhibition of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide probe binding to BCL-xl (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50162797(CHEMBL3793424)
Affinity DataKi: <0.0100nMAssay Description:Binding affinity to Bcl-XL (unknown origin) by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50030754(CHEMBL3342332)
Affinity DataKi: <0.0100nMAssay Description:Binding affinity to Bcl-XL (unknown origin) by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50162797(CHEMBL3793424)
Affinity DataKi: <0.0100nMAssay Description:Inhibition of Bcl-xL (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50162797(CHEMBL3793424)
Affinity DataKi: <0.0100nMAssay Description:Inhibition of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide probe binding to BCL-xl (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50030759(CHEMBL3342194)
Affinity DataKi: <0.0100nMAssay Description:Inhibition of BCL-XL (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50030756(CHEMBL3342197)
Affinity DataKi:  0.0200nMAssay Description:Inhibition of BCL-XL (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM209074(US9266877, 20)
Affinity DataKi:  0.0270nMAssay Description:Inhibition of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide probe binding to BCL-xl (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50030757(CHEMBL3342196)
Affinity DataKi:  0.0300nMAssay Description:Inhibition of BCL-XL (unknown origin) incubated for 1 hr in presence of 1% human serum by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50030751(CHEMBL3342334)
Affinity DataKi:  0.0300nMAssay Description:Inhibition of BCL-XL (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM185629(US9156856, 42 | US9493431, 42)
Affinity DataKi:  0.0390nM ΔG°:  -59.4kJ/moleT: 2°CAssay Description:Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 μM (2× starting concentration; 10% DMSO) and 10 μ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50030755(CHEMBL3342198)
Affinity DataKi:  0.0400nMAssay Description:Inhibition of BCL-XL (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM139051(US8883784, 12)
Affinity DataKi:  0.0400nM ΔG°:  -59.3kJ/moleT: 2°CAssay Description:The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50030761(CHEMBL3342192)
Affinity DataKi:  0.0420nMAssay Description:Inhibition of BCL-XL (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM209066(US9266877, 12)
Affinity DataKi:  0.0440nMAssay Description:Inhibition of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide probe binding to BCL-xl (unknown origin) incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50030758(CHEMBL3342195)
Affinity DataKi:  0.0500nMAssay Description:Inhibition of BCL-XL (unknown origin) incubated for 1 hr in presence of 1% human serum by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM185628(US9156856, 41 | US9493431, 41)
Affinity DataKi:  0.0530nM ΔG°:  -58.7kJ/moleT: 2°CAssay Description:Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 μM (2× starting concentration; 10% DMSO) and 10 μ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50270877((R)-4-(4-((2-(4-chlorophenyl)-5,5-dimethylcyclohex...)
Affinity DataKi:  0.0550nMAssay Description:Inhibition of Bcl-xL (unknown origin)More data for this Ligand-Target Pair
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM139050(US8883784, 11)
Affinity DataKi:  0.0600nM ΔG°:  -58.3kJ/moleT: 2°CAssay Description:The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM185598(US9156856, 8 | US9493431, 8)
Affinity DataKi:  0.0640nM ΔG°:  -58.2kJ/moleT: 2°CAssay Description:Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 μM (2× starting concentration; 10% DMSO) and 10 μ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBcl-2-like protein 1(Mus musculus (Mouse))
Abbvie

US Patent
LigandPNGBDBM21447(4-(4-{[2-(4-chlorophenyl)phenyl]methyl}piperazin-1...)
Affinity DataKi:  0.0800nMAssay Description:The inhibition constant (Ki) is the dissociation constant of an enzyme-inhibitor complex or a protein/small molecule complex, wherein the small molec...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM185597(US9156856, 7 | US9493431, 7)
Affinity DataKi:  0.0840nM ΔG°:  -57.5kJ/moleT: 2°CAssay Description:Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 μM (2× starting concentration; 10% DMSO) and 10 μ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM209230(US9266877, 176)
Affinity DataKi: <0.100nM ΔG°: <-57.1kJ/moleT: 2°CAssay Description:The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM139041(US8883784, 2)
Affinity DataKi:  0.100nM ΔG°:  -57.1kJ/moleT: 2°CAssay Description:The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM209232(US9266877, 178)
Affinity DataKi: <0.100nM ΔG°: <-57.1kJ/moleT: 2°CAssay Description:The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM209233(US9266877, 179)
Affinity DataKi: <0.100nM ΔG°: <-57.1kJ/moleT: 2°CAssay Description:The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM209235(US9266877, 181)
Affinity DataKi: <0.100nM ΔG°: <-57.1kJ/moleT: 2°CAssay Description:The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM209238(US9266877, 184)
Affinity DataKi: <0.100nM ΔG°: <-57.1kJ/moleT: 2°CAssay Description:The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM209239(US9266877, 185)
Affinity DataKi: <0.100nM ΔG°: <-57.1kJ/moleT: 2°CAssay Description:The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM209240(US9266877, 186)
Affinity DataKi: <0.100nM ΔG°: <-57.1kJ/moleT: 2°CAssay Description:The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50030754(CHEMBL3342332)
Affinity DataKi:  0.100nMAssay Description:Inhibition of BCL-XL (unknown origin) incubated for 1 hr in presence of 1% human serum by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50270877((R)-4-(4-((2-(4-chlorophenyl)-5,5-dimethylcyclohex...)
Affinity DataKi: <0.100nMAssay Description:Inhibition of F-Bak binding to GST-tagged BCL-XL (unknown origin) measured after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM209156(US9266877, 102)
Affinity DataKi: <0.100nM ΔG°: <-57.1kJ/moleT: 2°CAssay Description:The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM209160(US9266877, 106)
Affinity DataKi:  0.100nM ΔG°:  -57.1kJ/moleT: 2°CAssay Description:The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM209170(US9266877, 116)
Affinity DataKi: <0.100nM ΔG°: <-57.1kJ/moleT: 2°CAssay Description:The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM209171(US9266877, 117)
Affinity DataKi: <0.100nM ΔG°: <-57.1kJ/moleT: 2°CAssay Description:The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM209173(US9266877, 119)
Affinity DataKi: <0.100nM ΔG°: <-57.1kJ/moleT: 2°CAssay Description:The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM209175(US9266877, 121)
Affinity DataKi:  0.100nM ΔG°:  -57.1kJ/moleT: 2°CAssay Description:The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM209177(US9266877, 123)
Affinity DataKi: <0.100nM ΔG°: <-57.1kJ/moleT: 2°CAssay Description:The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM209178(US9266877, 124)
Affinity DataKi: <0.100nM ΔG°: <-57.1kJ/moleT: 2°CAssay Description:The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM209183(US9266877, 129)
Affinity DataKi: <0.100nM ΔG°: <-57.1kJ/moleT: 2°CAssay Description:The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM209184(US9266877, 130)
Affinity DataKi: <0.100nM ΔG°: <-57.1kJ/moleT: 2°CAssay Description:The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM209185(US9266877, 131)
Affinity DataKi: <0.100nM ΔG°: <-57.1kJ/moleT: 2°CAssay Description:The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM209188(US9266877, 134)
Affinity DataKi: <0.100nM ΔG°: <-57.1kJ/moleT: 2°CAssay Description:The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBcl-2-like protein 1(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM209192(US9266877, 138)
Affinity DataKi: <0.100nM ΔG°: <-57.1kJ/moleT: 2°CAssay Description:The measurement of competition of compounds of Formula (I) with F-Bak for a Bcl-2 family protein (Bcl-xL) binding site using a Time Resolved Fluoresc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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