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TargetArginase-1(Human)
Oncoarendi Therapeutics

Curated by ChEMBL
LigandPNGBDBM50561046(CHEMBL4790798)
Affinity DataKi: <10nMAssay Description:Inhibition of human Arg1 using L-arginine as substrate after 60 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetArginase-1(Human)
Oncoarendi Therapeutics

Curated by ChEMBL
LigandPNGBDBM50561045(CHEMBL4758805)
Affinity DataKi: <10nMAssay Description:Inhibition of human Arg1 using L-arginine as substrate after 60 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetArginase-1(Rat)
Flinders University

Curated by ChEMBL
LigandPNGBDBM50350311(CHEMBL1812661)
Affinity DataKi:  110nMAssay Description:Inhibition of N-terminal hexa-histidine tagged thrombin-cleavable rat arginase 1 expressed in Escherichia coli DE3 cells measured after 90 mins by co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetArginase-1(Rat)
Flinders University

Curated by ChEMBL
LigandPNGBDBM50008099(CHEMBL1234777)
Affinity DataKi:  500nMAssay Description:Inhibition of Sprague-Dawley rat liver arginase 1 assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetArginase-1(Human)
Oncoarendi Therapeutics

Curated by ChEMBL
LigandPNGBDBM50316603(2-(S)-amino-5-(2-aminoimidazol-1-yl)pentanoic acid...)
Affinity DataKi:  4.00E+3nMAssay Description:Inhibition of human recombinant full length arginase 1 expressed in Escherichia coli BL21(DE3) by fixed point assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetArginase-1(Rat)
Flinders University

Curated by ChEMBL
LigandPNGBDBM50230418(N-OMEGA-HYDROXY-L-ARGININE | Nomega-hydroxy-L-argi...)
Affinity DataKi:  1.00E+4nMAssay Description:Inhibition of Sprague-Dawley rat liver arginase 1 assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetArginase-1(Bovine)
Christian-Albrechts-University of Kiel

Curated by ChEMBL
LigandPNGBDBM50375814(CHEMBL260628)
Affinity DataKi:  1.71E+4nMAssay Description:Inhibition of bovine liver arginaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetArginase-1(Bovine)
Christian-Albrechts-University of Kiel

Curated by ChEMBL
LigandPNGBDBM50230418(N-OMEGA-HYDROXY-L-ARGININE | Nomega-hydroxy-L-argi...)
Affinity DataKi:  3.00E+4nMAssay Description:Inhibition of bovine liver arginaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetArginase-1(Rat)
Flinders University

Curated by ChEMBL
LigandPNGBDBM50354832(CHEMBL1834160)
Affinity DataKi:  6.00E+4nMAssay Description:Binding affinity to rat Arg IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetArginase-1(Bovine)
Christian-Albrechts-University of Kiel

Curated by ChEMBL
LigandPNGBDBM50553165(CHEMBL4754674)
Affinity DataKi:  8.20E+4nMAssay Description:Mixed type inhibition of recombinant bovine liver ARGI using L-arginine as substrate incubated for 60 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetArginase-1(Bovine)
Christian-Albrechts-University of Kiel

Curated by ChEMBL
LigandPNGBDBM50553165(CHEMBL4754674)
Affinity DataKi:  8.20E+4nMAssay Description:Mixed type inhibition of recombinant bovine liver ARGI using L-arginine as substrate incubated for 60 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetArginase-1(Bovine)
Christian-Albrechts-University of Kiel

Curated by ChEMBL
LigandPNGBDBM50553165(CHEMBL4754674)
Affinity DataKi:  8.20E+4nMAssay Description:Mixed type inhibition of recombinant bovine liver ARGI using L-arginine as substrate incubated for 60 mins by Cornish-Bowden plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetArginase-1(Bovine)
Christian-Albrechts-University of Kiel

Curated by ChEMBL
LigandPNGBDBM50608139(CHEMBL5287570)
Affinity DataKi:  9.00E+4nMAssay Description:Binding affinity to bovine liver Arg IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetArginase-1(Bovine)
Christian-Albrechts-University of Kiel

Curated by ChEMBL
LigandPNGBDBM50045936(CHEMBL69863 | 4-(3,5-dihydroxystyryl)benzene-1,2-d...)
Affinity DataKi:  1.36E+5nMAssay Description:Mixed type inhibition of recombinant bovine liver ARGI using L-arginine as substrate incubated for 60 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetArginase-1(Bovine)
Christian-Albrechts-University of Kiel

Curated by ChEMBL
LigandPNGBDBM50045936(CHEMBL69863 | 4-(3,5-dihydroxystyryl)benzene-1,2-d...)
Affinity DataKi:  1.36E+5nMAssay Description:Mixed type inhibition of recombinant bovine liver ARGI using L-arginine as substrate incubated for 60 mins by Cornish-Bowden plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetArginase-1(Bovine)
Christian-Albrechts-University of Kiel

Curated by ChEMBL
LigandPNGBDBM50045936(CHEMBL69863 | 4-(3,5-dihydroxystyryl)benzene-1,2-d...)
Affinity DataKi:  1.36E+5nMAssay Description:Mixed type inhibition of recombinant bovine liver ARGI using L-arginine as substrate incubated for 60 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2022
Entry Details Article
PubMed
TargetArginase-1(Human)
Oncoarendi Therapeutics

Curated by ChEMBL
LigandPNGBDBM50462601(CHEMBL4250607)
Affinity DataKi:  2.75E+5nMAssay Description:Irreversible inhibition of human arginase 1 using thioarginine as substrate measured up to 360 mins by UV micro plate methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetArginase-1(Human)
Oncoarendi Therapeutics

Curated by ChEMBL
LigandPNGBDBM50316607(L-2-aminohistidine | 2-amino-L-histidine | CHEMBL1...)
Affinity DataKi:  3.00E+5nMAssay Description:Inhibition of human recombinant full length arginase 1 expressed in Escherichia coli BL21(DE3) by fixed point assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetArginase-1(Human)
Oncoarendi Therapeutics

Curated by ChEMBL
LigandPNGBDBM50462600(CHEMBL4238387)
Affinity DataKi:  3.82E+5nMAssay Description:Irreversible inhibition of human arginase 1 using thioarginine as substrate measured up to 360 mins by UV micro plate methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetArginase-1(Human)
Oncoarendi Therapeutics

Curated by ChEMBL
LigandPNGBDBM50316604((S)-2-amino-5-(imidazol-2-ylamino)pentanoic acid |...)
Affinity DataKi:  5.00E+5nMAssay Description:Inhibition of human recombinant full length arginase 1 expressed in Escherichia coli BL21(DE3) by fixed point assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetArginase-1(Human)
Oncoarendi Therapeutics

Curated by ChEMBL
LigandPNGBDBM50316608(1H-imidazol-2-amine | 2-Aminoimidazole | 1H-Imidaz...)
Affinity DataKi:  3.60E+6nMAssay Description:Inhibition of human recombinant full length arginase 1 expressed in Escherichia coli BL21(DE3) by fixed point assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetArginase-1(Human)
Oncoarendi Therapeutics

Curated by ChEMBL
LigandPNGBDBM50316603(2-(S)-amino-5-(2-aminoimidazol-1-yl)pentanoic acid...)
Affinity DataKi:  3.00E+7nMAssay Description:Binding affinity to human Arg IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetArginase-1(Human)
Oncoarendi Therapeutics

Curated by ChEMBL
LigandPNGBDBM50316606(2-aminohomohistidine | (2S)-2-amino-4-(2-amino-1H-...)
Affinity DataKi:  3.00E+6nMAssay Description:Inhibition of human recombinant full length arginase 1 expressed in Escherichia coli BL21(DE3) by fixed point assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetArginase-1(Human)
Oncoarendi Therapeutics

Curated by ChEMBL
LigandPNGBDBM50316605(2-amino-5-(2-aminoimidazol-4-yl)pentanoic acid | C...)
Affinity DataKi: >8.00E+7nMAssay Description:Inhibition of human recombinant full length arginase 1 expressed in Escherichia coli BL21(DE3) by fixed point assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed