TargetProprotein convertase subtilisin/kexin type 5(Homo sapiens (Human))
Centre Hospitalier Universitaire Vaudois (Chuv)
Curated by ChEMBL
Centre Hospitalier Universitaire Vaudois (Chuv)
Curated by ChEMBL
Affinity DataKi: 0.120nMAssay Description:Inhibition of recombinant C-terminal truncated human SPC6 expressed in drosophila Schneider 2 cells after 1 hr by spectrofluorometryMore data for this Ligand-Target Pair
TargetProprotein convertase subtilisin/kexin type 5(Homo sapiens (Human))
Centre Hospitalier Universitaire Vaudois (Chuv)
Curated by ChEMBL
Centre Hospitalier Universitaire Vaudois (Chuv)
Curated by ChEMBL
Affinity DataKi: 1.60nMAssay Description:Inhibition of human PC5/6 expressed in Drosophila schneider 2 cells by fluorescence assayMore data for this Ligand-Target Pair
TargetProprotein convertase subtilisin/kexin type 5(Homo sapiens (Human))
Centre Hospitalier Universitaire Vaudois (Chuv)
Curated by ChEMBL
Centre Hospitalier Universitaire Vaudois (Chuv)
Curated by ChEMBL
Affinity DataKi: 3.60nMAssay Description:Inhibition of human PC5/6 expressed in Drosophila schneider 2 cells by fluorescence assayMore data for this Ligand-Target Pair
TargetHepatocyte growth factor activator(Homo sapiens (Human))
Universidade Federal De Pernambuco
Curated by ChEMBL
Universidade Federal De Pernambuco
Curated by ChEMBL
Affinity DataKi: 3.70nMAssay Description:Inhibition of recombinant HGFA serine protease domain (unknown origin) preincubated for 30 mins followed by Boc-QLR-AMC substrate addition by fluores...More data for this Ligand-Target Pair
TargetProprotein convertase subtilisin/kexin type 5(Homo sapiens (Human))
Centre Hospitalier Universitaire Vaudois (Chuv)
Curated by ChEMBL
Centre Hospitalier Universitaire Vaudois (Chuv)
Curated by ChEMBL
Affinity DataKi: 6.30nMAssay Description:Inhibition of human PC5/6 expressed in Drosophila schneider 2 cells by fluorescence assayMore data for this Ligand-Target Pair
TargetHepatocyte growth factor activator(Homo sapiens (Human))
Universidade Federal De Pernambuco
Curated by ChEMBL
Universidade Federal De Pernambuco
Curated by ChEMBL
Affinity DataKi: 7.20nMAssay Description:Inhibition of recombinant HGFA serine protease domain (unknown origin) preincubated for 30 mins followed by Boc-QLR-AMC substrate addition by fluores...More data for this Ligand-Target Pair
TargetHepatocyte growth factor activator(Homo sapiens (Human))
Universidade Federal De Pernambuco
Curated by ChEMBL
Universidade Federal De Pernambuco
Curated by ChEMBL
Affinity DataKi: 12nMAssay Description:Inhibition of recombinant HGFA (unknown origin) using Boc-QLR-AMC as substrate by chromogenic proteolytic assayMore data for this Ligand-Target Pair
TargetHepatocyte growth factor activator(Homo sapiens (Human))
Universidade Federal De Pernambuco
Curated by ChEMBL
Universidade Federal De Pernambuco
Curated by ChEMBL
Affinity DataKi: 17nMAssay Description:Inhibition of recombinant HGFA (unknown origin) using Boc-QLR-AMC as substrate by chromogenic proteolytic assayMore data for this Ligand-Target Pair
TargetHepatocyte growth factor activator(Homo sapiens (Human))
Universidade Federal De Pernambuco
Curated by ChEMBL
Universidade Federal De Pernambuco
Curated by ChEMBL
Affinity DataKi: 21nMAssay Description:Inhibition of recombinant HGFA (unknown origin) using Boc-QLR-AMC as substrate by chromogenic proteolytic assayMore data for this Ligand-Target Pair
TargetHepatocyte growth factor activator(Homo sapiens (Human))
Universidade Federal De Pernambuco
Curated by ChEMBL
Universidade Federal De Pernambuco
Curated by ChEMBL
Affinity DataKi: 24nMAssay Description:Inhibition of recombinant HGFA (unknown origin) using Boc-QLR-AMC as substrate by chromogenic proteolytic assayMore data for this Ligand-Target Pair
TargetHepatocyte growth factor activator(Homo sapiens (Human))
Universidade Federal De Pernambuco
Curated by ChEMBL
Universidade Federal De Pernambuco
Curated by ChEMBL
Affinity DataKi: 25nMAssay Description:Inhibition of recombinant HGFA (unknown origin) using Boc-QLR-AMC as substrate by chromogenic proteolytic assayMore data for this Ligand-Target Pair
TargetHepatocyte growth factor activator(Homo sapiens (Human))
Universidade Federal De Pernambuco
Curated by ChEMBL
Universidade Federal De Pernambuco
Curated by ChEMBL
Affinity DataKi: 25nMAssay Description:Inhibition of recombinant N-terminal His-tagged HGFA (unknown origin) expressed in baculovirus-infected Sf9 cells using Boc-QLR-AMC as substrate incu...More data for this Ligand-Target Pair
TargetHepatocyte growth factor activator(Homo sapiens (Human))
Universidade Federal De Pernambuco
Curated by ChEMBL
Universidade Federal De Pernambuco
Curated by ChEMBL
Affinity DataKi: 30nMAssay Description:Inhibition of HGFA catalytic domain (unknown origin) preincubated for 30 mins followed by Boc-QLR-AMC substrate addition and measured for 1 hr by flu...More data for this Ligand-Target Pair
TargetHepatocyte growth factor activator(Homo sapiens (Human))
Universidade Federal De Pernambuco
Curated by ChEMBL
Universidade Federal De Pernambuco
Curated by ChEMBL
Affinity DataKi: 33nMAssay Description:Inhibition of HGFA catalytic domain (unknown origin) preincubated for 30 mins followed by Boc-QLR-AMC substrate addition and measured for 1 hr by flu...More data for this Ligand-Target Pair
TargetHepatocyte growth factor activator(Homo sapiens (Human))
Universidade Federal De Pernambuco
Curated by ChEMBL
Universidade Federal De Pernambuco
Curated by ChEMBL
Affinity DataKi: 53nMAssay Description:Inhibition of recombinant HGFA (unknown origin) using Boc-QLR-AMC as substrate by chromogenic proteolytic assayMore data for this Ligand-Target Pair
TargetHepatocyte growth factor activator(Homo sapiens (Human))
Universidade Federal De Pernambuco
Curated by ChEMBL
Universidade Federal De Pernambuco
Curated by ChEMBL
Affinity DataKi: 56nMAssay Description:Inhibition of recombinant HGFA (unknown origin) using Boc-QLR-AMC as substrate by chromogenic proteolytic assayMore data for this Ligand-Target Pair
TargetHepatocyte growth factor activator(Homo sapiens (Human))
Universidade Federal De Pernambuco
Curated by ChEMBL
Universidade Federal De Pernambuco
Curated by ChEMBL
Affinity DataKi: 57nMAssay Description:Inhibition of recombinant HGFA (unknown origin) using Boc-QLR-AMC as substrate by chromogenic proteolytic assayMore data for this Ligand-Target Pair
TargetHepatocyte growth factor activator(Homo sapiens (Human))
Universidade Federal De Pernambuco
Curated by ChEMBL
Universidade Federal De Pernambuco
Curated by ChEMBL
Affinity DataKi: 58nMAssay Description:Inhibition of recombinant HGFA (unknown origin) using Boc-QLR-AMC as substrate by chromogenic proteolytic assayMore data for this Ligand-Target Pair
TargetHepatocyte growth factor activator(Homo sapiens (Human))
Universidade Federal De Pernambuco
Curated by ChEMBL
Universidade Federal De Pernambuco
Curated by ChEMBL
Affinity DataKi: 60nMAssay Description:Inhibition of recombinant HGFA (unknown origin) using Boc-QLR-AMC as substrate by chromogenic proteolytic assayMore data for this Ligand-Target Pair
TargetHepatocyte growth factor activator(Homo sapiens (Human))
Universidade Federal De Pernambuco
Curated by ChEMBL
Universidade Federal De Pernambuco
Curated by ChEMBL
Affinity DataKi: 63nMAssay Description:Inhibition of recombinant HGFA (unknown origin) using Boc-QLR-AMC as substrate by chromogenic proteolytic assayMore data for this Ligand-Target Pair
TargetHepatocyte growth factor activator(Homo sapiens (Human))
Universidade Federal De Pernambuco
Curated by ChEMBL
Universidade Federal De Pernambuco
Curated by ChEMBL
Affinity DataKi: 65nMAssay Description:Inhibition of recombinant HGFA (unknown origin) using Boc-QLR-AMC as substrate by chromogenic proteolytic assayMore data for this Ligand-Target Pair
TargetHepatocyte growth factor activator(Homo sapiens (Human))
Universidade Federal De Pernambuco
Curated by ChEMBL
Universidade Federal De Pernambuco
Curated by ChEMBL
Affinity DataKi: 79nMAssay Description:Inhibition of recombinant HGFA (unknown origin) using Boc-QLR-AMC as substrate by chromogenic proteolytic assayMore data for this Ligand-Target Pair
TargetHepatocyte growth factor activator(Homo sapiens (Human))
Universidade Federal De Pernambuco
Curated by ChEMBL
Universidade Federal De Pernambuco
Curated by ChEMBL
Affinity DataKi: 80nMAssay Description:Inhibition of recombinant HGFA (unknown origin) using Boc-QLR-AMC as substrate by chromogenic proteolytic assayMore data for this Ligand-Target Pair
TargetHepatocyte growth factor activator(Homo sapiens (Human))
Universidade Federal De Pernambuco
Curated by ChEMBL
Universidade Federal De Pernambuco
Curated by ChEMBL
Affinity DataKi: 81nMAssay Description:Inhibition of recombinant HGFA (unknown origin) using Boc-QLR-AMC as substrate by chromogenic proteolytic assayMore data for this Ligand-Target Pair
TargetProprotein convertase subtilisin/kexin type 5(Homo sapiens (Human))
Centre Hospitalier Universitaire Vaudois (Chuv)
Curated by ChEMBL
Centre Hospitalier Universitaire Vaudois (Chuv)
Curated by ChEMBL
Affinity DataKi: 85nMAssay Description:Inhibition of human PC5/6 expressed in Drosophila schneider 2 cells by fluorescence assayMore data for this Ligand-Target Pair
TargetHepatocyte growth factor activator(Homo sapiens (Human))
Universidade Federal De Pernambuco
Curated by ChEMBL
Universidade Federal De Pernambuco
Curated by ChEMBL
Affinity DataKi: 96nMAssay Description:Inhibition of recombinant HGFA (unknown origin) using Boc-QLR-AMC as substrate by chromogenic proteolytic assayMore data for this Ligand-Target Pair
TargetHepatocyte growth factor activator(Homo sapiens (Human))
Universidade Federal De Pernambuco
Curated by ChEMBL
Universidade Federal De Pernambuco
Curated by ChEMBL
Affinity DataKi: 103nMAssay Description:Inhibition of recombinant HGFA (unknown origin) using Boc-QLR-AMC as substrate by chromogenic proteolytic assayMore data for this Ligand-Target Pair
TargetHepatocyte growth factor activator(Homo sapiens (Human))
Universidade Federal De Pernambuco
Curated by ChEMBL
Universidade Federal De Pernambuco
Curated by ChEMBL
Affinity DataKi: 160nMAssay Description:Inhibition of human recombinant hepatocyte growth factor activator using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysisMore data for this Ligand-Target Pair
TargetProprotein convertase subtilisin/kexin type 5(Homo sapiens (Human))
Centre Hospitalier Universitaire Vaudois (Chuv)
Curated by ChEMBL
Centre Hospitalier Universitaire Vaudois (Chuv)
Curated by ChEMBL
Affinity DataKi: 173nMAssay Description:Inhibition of human PC5/6 expressed in Drosophila schneider 2 cells by fluorescence assayMore data for this Ligand-Target Pair
TargetHepatocyte growth factor activator(Homo sapiens (Human))
Universidade Federal De Pernambuco
Curated by ChEMBL
Universidade Federal De Pernambuco
Curated by ChEMBL
Affinity DataKi: 182nMAssay Description:Inhibition of recombinant HGFA (unknown origin) using Boc-QLR-AMC as substrate by chromogenic proteolytic assayMore data for this Ligand-Target Pair
TargetProprotein convertase subtilisin/kexin type 5(Homo sapiens (Human))
Centre Hospitalier Universitaire Vaudois (Chuv)
Curated by ChEMBL
Centre Hospitalier Universitaire Vaudois (Chuv)
Curated by ChEMBL
Affinity DataKi: 188nMAssay Description:Inhibition of human recombinant PC5/6 assessed as fluorescent Pyr-RTKR-AMC substrate cleavageMore data for this Ligand-Target Pair
TargetHepatocyte growth factor activator(Homo sapiens (Human))
Universidade Federal De Pernambuco
Curated by ChEMBL
Universidade Federal De Pernambuco
Curated by ChEMBL
Affinity DataKi: 188nMAssay Description:Inhibition of recombinant HGFA (unknown origin) using Boc-QLR-AMC as substrate by chromogenic proteolytic assayMore data for this Ligand-Target Pair
TargetHepatocyte growth factor activator(Homo sapiens (Human))
Universidade Federal De Pernambuco
Curated by ChEMBL
Universidade Federal De Pernambuco
Curated by ChEMBL
Affinity DataKi: 230nMAssay Description:Inhibition of human recombinant hepatocyte growth factor activator using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysisMore data for this Ligand-Target Pair
TargetProprotein convertase subtilisin/kexin type 5(Homo sapiens (Human))
Centre Hospitalier Universitaire Vaudois (Chuv)
Curated by ChEMBL
Centre Hospitalier Universitaire Vaudois (Chuv)
Curated by ChEMBL
Affinity DataKi: 232nMAssay Description:Inhibition of human recombinant PC5/6 assessed as fluorescent Pyr-RTKR-AMC substrate cleavageMore data for this Ligand-Target Pair
TargetHepatocyte growth factor activator(Homo sapiens (Human))
Universidade Federal De Pernambuco
Curated by ChEMBL
Universidade Federal De Pernambuco
Curated by ChEMBL
Affinity DataKi: 332nMAssay Description:Inhibition of recombinant HGFA (unknown origin) using Boc-QLR-AMC as substrate by chromogenic proteolytic assayMore data for this Ligand-Target Pair
TargetHepatocyte growth factor activator(Homo sapiens (Human))
Universidade Federal De Pernambuco
Curated by ChEMBL
Universidade Federal De Pernambuco
Curated by ChEMBL
Affinity DataKi: 350nMAssay Description:Inhibition of human recombinant hepatocyte growth factor activator using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysisMore data for this Ligand-Target Pair
TargetHepatocyte growth factor activator(Homo sapiens (Human))
Universidade Federal De Pernambuco
Curated by ChEMBL
Universidade Federal De Pernambuco
Curated by ChEMBL
Affinity DataKi: 380nMAssay Description:Inhibition of human recombinant hepatocyte growth factor activator using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysisMore data for this Ligand-Target Pair
TargetHepatocyte growth factor activator(Homo sapiens (Human))
Universidade Federal De Pernambuco
Curated by ChEMBL
Universidade Federal De Pernambuco
Curated by ChEMBL
Affinity DataKi: 430nMAssay Description:Inhibition of human recombinant hepatocyte growth factor activator using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysisMore data for this Ligand-Target Pair
TargetProprotein convertase subtilisin/kexin type 5(Homo sapiens (Human))
Centre Hospitalier Universitaire Vaudois (Chuv)
Curated by ChEMBL
Centre Hospitalier Universitaire Vaudois (Chuv)
Curated by ChEMBL
Affinity DataKi: 433nMAssay Description:Inhibition of human recombinant PC5/6 assessed as fluorescent Pyr-RTKR-AMC substrate cleavageMore data for this Ligand-Target Pair
TargetHepatocyte growth factor activator(Homo sapiens (Human))
Universidade Federal De Pernambuco
Curated by ChEMBL
Universidade Federal De Pernambuco
Curated by ChEMBL
Affinity DataKi: 440nMAssay Description:Inhibition of human recombinant hepatocyte growth factor activator using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysisMore data for this Ligand-Target Pair
TargetHepatocyte growth factor activator(Homo sapiens (Human))
Universidade Federal De Pernambuco
Curated by ChEMBL
Universidade Federal De Pernambuco
Curated by ChEMBL
Affinity DataKi: 468nMAssay Description:Inhibition of HGFA catalytic domain (unknown origin) preincubated for 30 mins followed by Boc-QLR-AMC substrate addition and measured for 1 hr by flu...More data for this Ligand-Target Pair
TargetHepatocyte growth factor activator(Homo sapiens (Human))
Universidade Federal De Pernambuco
Curated by ChEMBL
Universidade Federal De Pernambuco
Curated by ChEMBL
Affinity DataKi: 480nMAssay Description:Inhibition of human recombinant hepatocyte growth factor activator using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysisMore data for this Ligand-Target Pair
TargetProprotein convertase subtilisin/kexin type 5(Homo sapiens (Human))
Centre Hospitalier Universitaire Vaudois (Chuv)
Curated by ChEMBL
Centre Hospitalier Universitaire Vaudois (Chuv)
Curated by ChEMBL
Affinity DataKi: 492nMAssay Description:Inhibition of human recombinant PC5/6 assessed as fluorescent Pyr-RTKR-AMC substrate cleavageMore data for this Ligand-Target Pair
TargetHepatocyte growth factor activator(Homo sapiens (Human))
Universidade Federal De Pernambuco
Curated by ChEMBL
Universidade Federal De Pernambuco
Curated by ChEMBL
Affinity DataKi: 520nMAssay Description:Inhibition of human recombinant hepatocyte growth factor activator using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysisMore data for this Ligand-Target Pair
TargetHepatocyte growth factor activator(Homo sapiens (Human))
Universidade Federal De Pernambuco
Curated by ChEMBL
Universidade Federal De Pernambuco
Curated by ChEMBL
Affinity DataKi: 590nMAssay Description:Inhibition of HGFA (unknown origin) after 40 mins by Eadie-Hofstee plot analysisMore data for this Ligand-Target Pair
TargetProprotein convertase subtilisin/kexin type 5(Homo sapiens (Human))
Centre Hospitalier Universitaire Vaudois (Chuv)
Curated by ChEMBL
Centre Hospitalier Universitaire Vaudois (Chuv)
Curated by ChEMBL
Affinity DataKi: 649nMAssay Description:Inhibition of human recombinant PC5/6 assessed as fluorescent Pyr-RTKR-AMC substrate cleavageMore data for this Ligand-Target Pair
TargetProprotein convertase subtilisin/kexin type 5(Homo sapiens (Human))
Centre Hospitalier Universitaire Vaudois (Chuv)
Curated by ChEMBL
Centre Hospitalier Universitaire Vaudois (Chuv)
Curated by ChEMBL
Affinity DataKi: 806nMAssay Description:Inhibition of human recombinant PC5/6 assessed as fluorescent Pyr-RTKR-AMC substrate cleavageMore data for this Ligand-Target Pair
TargetHepatocyte growth factor activator(Homo sapiens (Human))
Universidade Federal De Pernambuco
Curated by ChEMBL
Universidade Federal De Pernambuco
Curated by ChEMBL
Affinity DataKi: 880nMAssay Description:Inhibition of human recombinant hepatocyte growth factor activator using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysisMore data for this Ligand-Target Pair
TargetHepatocyte growth factor activator(Homo sapiens (Human))
Universidade Federal De Pernambuco
Curated by ChEMBL
Universidade Federal De Pernambuco
Curated by ChEMBL
Affinity DataKi: 963nMAssay Description:Inhibition of HGFA catalytic domain (unknown origin) preincubated for 30 mins followed by Boc-QLR-AMC substrate addition and measured for 1 hr by flu...More data for this Ligand-Target Pair
TargetHepatocyte growth factor activator(Homo sapiens (Human))
Universidade Federal De Pernambuco
Curated by ChEMBL
Universidade Federal De Pernambuco
Curated by ChEMBL
Affinity DataKi: 1.08E+3nMAssay Description:Inhibition of human recombinant hepatocyte growth factor activator using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysisMore data for this Ligand-Target Pair