Compile Data Set for Download or QSAR
Report error Found 6 of ki data for polymerid = 5271,50002333
TargetAcyl-protein thioesterase 1(Rat)
Peking University First Hospital

Curated by ChEMBL
LigandPNGBDBM50543969(CHEMBL4640030)
Affinity DataKi:  23nMAssay Description:Inhibition of recombinant N-terminal FLAG-tagged FAP (unknown origin) (38 to 760 residues) expressed in HEK293 cells using AMCC as substrate by fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetAcyl-protein thioesterase 1(Human)
University of Michigan

LigandPNGBDBM207991(ML348)
Affinity DataKi:  280nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAcyl-protein thioesterase 1(Human)
University of Michigan

LigandPNGBDBM207991(ML348)
Affinity DataKi:  300nMAssay Description:Inhibition of APT1 (unknown origin) by FluPol-ABPP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAcyl-protein thioesterase 1(Human)
University of Michigan

LigandPNGBDBM50496627(CHEMBL3133032)
Affinity DataKi:  990nMAssay Description:Inhibition of APT1 (unknown origin) by enzyme kinetic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetAcyl-protein thioesterase 1(Human)
University of Michigan

LigandPNGBDBM207992(ML349)
Affinity DataKi: >1.00E+4nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2017
Entry Details Article
PubMed
TargetAcyl-protein thioesterase 1(Human)
University of Michigan

LigandPNGBDBM207992(ML349)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of APT1 (unknown origin) by FluPol-ABPP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed