Compile Data Set for Download or QSAR
Report error Found 75 of ki data for polymerid = 5886
TargetBcl-2-like protein 2(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM21447(4-(4-{[2-(4-chlorophenyl)phenyl]methyl}piperazin-1...)
Affinity DataKi: <1nMAssay Description:Inhibition of Bcl-w (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2020
Entry Details Article
PubMed
TargetBcl-2-like protein 2(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50653011(CHEMBL5712050)
Affinity DataKi:  2nMAssay Description:Binding affinity to BCL-W (unknown origin) assessed as dissociation constant incubated for 1 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetBcl-2-like protein 2(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50162797(CHEMBL3793424)
Affinity DataKi:  4nMAssay Description:Binding affinity to BCL-W (unknown origin) assessed as dissociation constant incubated for 1 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetBcl-2-like protein 2(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50030754(CHEMBL3342332)
Affinity DataKi:  8nMAssay Description:Binding affinity to BCL-W (unknown origin) assessed as dissociation constant incubated for 1 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetBcl-2-like protein 2(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50030754(CHEMBL3342332)
Affinity DataKi:  19nMAssay Description:Binding affinity to BCL-W (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMed
TargetBcl-2-like protein 2(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50270877(ABT-263 | (R)-4-(4-((2-(4-chlorophenyl)-5,5-dimeth...)
Affinity DataKi:  21nMAssay Description:Binding affinity to BCL-W (unknown origin) assessed as dissociation constant incubated for 1 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetBcl-2-like protein 2(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50357756(CHEMBL1916194)
Affinity DataKi:  21nMAssay Description:Displacement of BODIPY-Bak conjugated peptide from GST-tagged human wild type Bcl-W expressed in Escherichia coli BL21 cells at 10 uM after 3 hrs by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetBcl-2-like protein 2(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM21434(N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)b...)
Affinity DataKi:  49nMAssay Description:Displacement of BODIPY-Bak conjugated peptide from GST-tagged human wild type Bcl-W expressed in Escherichia coli BL21 cells at 10 uM after 3 hrs by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetBcl-2-like protein 2(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50357753(CHEMBL1916191)
Affinity DataKi:  55nMAssay Description:Displacement of BODIPY-Bak conjugated peptide from GST-tagged human wild type Bcl-W expressed in Escherichia coli BL21 cells at 10 uM after 3 hrs by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetBcl-2-like protein 2(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50357755(CHEMBL1916193)
Affinity DataKi:  59nMAssay Description:Displacement of BODIPY-Bak conjugated peptide from GST-tagged human wild type Bcl-W expressed in Escherichia coli BL21 cells at 10 uM after 3 hrs by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetBcl-2-like protein 2(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50357752(CHEMBL1916190)
Affinity DataKi:  63nMAssay Description:Displacement of BODIPY-Bak conjugated peptide from GST-tagged human wild type Bcl-W expressed in Escherichia coli BL21 cells at 10 uM after 3 hrs by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetBcl-2-like protein 2(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50357754(CHEMBL1916192)
Affinity DataKi:  170nMAssay Description:Displacement of BODIPY-Bak conjugated peptide from GST-tagged human wild type Bcl-W expressed in Escherichia coli BL21 cells at 10 uM after 3 hrs by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetBcl-2-like protein 2(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50162774(ABT-199 | Venetoclax | US11420968, Example ABT-199)
Affinity DataKi:  245nMAssay Description:Binding affinity to Bcl-w (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2020
Entry Details Article
PubMed
TargetBcl-2-like protein 2(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50162774(ABT-199 | Venetoclax | US11420968, Example ABT-199)
Affinity DataKi:  245nMAssay Description:Displacement of fluorescent-labeled BID-BH3 peptide from human BCL-W expressed in Escherichia coli BL21 (DE3) assessed as inhibition constant by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetBcl-2-like protein 2(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50162774(ABT-199 | Venetoclax | US11420968, Example ABT-199)
Affinity DataKi:  245nMAssay Description:Binding affinity to Bcl-w (unknown origin) assessed as inhibition constant by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetBcl-2-like protein 2(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50162774(ABT-199 | Venetoclax | US11420968, Example ABT-199)
Affinity DataKi:  245nMAssay Description:Binding affinity to BCL-2 (unknown origin) assessed as inhibition constant by fluorescence polarization binding affinity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetBcl-2-like protein 2(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50162774(ABT-199 | Venetoclax | US11420968, Example ABT-199)
Affinity DataKi:  245nMAssay Description:Binding affinity to BCL-W (unknown origin) assessed as dissociation constant incubated for 1 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetBcl-2-like protein 2(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50270877(ABT-263 | (R)-4-(4-((2-(4-chlorophenyl)-5,5-dimeth...)
Affinity DataKi:  245nMAssay Description:Inhibition of BCL-W (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetBcl-2-like protein 2(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM21447(4-(4-{[2-(4-chlorophenyl)phenyl]methyl}piperazin-1...)
Affinity DataKi:  285nMAssay Description:Inhibition of Bcl-w (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetBcl-2-like protein 2(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM451097(US10676485, Example 7)
Affinity DataKi: >468nMAssay Description:Binding affinity to Bcl-W (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetBcl-2-like protein 2(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50078160(CHEMBL3417701)
Affinity DataKi: >660nMAssay Description:Inhibition of BCL-W (unknown origin) after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2016
Entry Details Article
PubMed
TargetBcl-2-like protein 2(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM356652(trans-4-(4-{[2-(4-chlorophenyl)-4,4-dimethylcycloh...)
Affinity DataKi:  852nMAssay Description:Binding affinity to BCL-W (unknown origin) assessed as dissociation constant incubated for 1 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetBcl-2-like protein 2(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50376902(CHEMBL408194)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of BH3 peptide binding to human recombinant BCL-w by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetBcl-2-like protein 2(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50372177(CHEMBL404899)
Affinity DataKi:  1.30E+3nMAssay Description:Inhibition of Bak peptide binding to human recombinant Bcl-wMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetBcl-2-like protein 2(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50013865(CHEMBL3265297)
Affinity DataKi:  1.36E+3nMAssay Description:Displacement of Flu-BID/FAM-BID from His-tagged BCLW (1 to 155) (unknown origin) expressed in Escherichia coli BL21(DE3) after 3 hrs by fluorescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetBcl-2-like protein 2(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50013867(CHEMBL3265299)
Affinity DataKi:  1.58E+3nMAssay Description:Displacement of Flu-BID/FAM-BID from His-tagged BCLW (1 to 155) (unknown origin) expressed in Escherichia coli BL21(DE3) after 3 hrs by fluorescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetBcl-2-like protein 2(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50013862(CHEMBL3265294)
Affinity DataKi:  1.92E+3nMAssay Description:Displacement of Flu-BID/FAM-BID from His-tagged BCLW (1 to 155) (unknown origin) expressed in Escherichia coli BL21(DE3) after 3 hrs by fluorescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetBcl-2-like protein 2(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM31802(Apogossypol | US9115061, Apogossypol)
Affinity DataKi:  2.10E+3nMAssay Description:Inhibition of Bcl-w (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetBcl-2-like protein 2(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50013863(CHEMBL3265295)
Affinity DataKi:  2.19E+3nMAssay Description:Displacement of Flu-BID/FAM-BID from His-tagged BCLW (1 to 155) (unknown origin) expressed in Escherichia coli BL21(DE3) after 3 hrs by fluorescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetBcl-2-like protein 2(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50372180(CHEMBL270646)
Affinity DataKi:  2.20E+3nMAssay Description:Inhibition of Bak peptide binding to human recombinant Bcl-wMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetBcl-2-like protein 2(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50372178(CHEMBL406312)
Affinity DataKi:  2.30E+3nMAssay Description:Inhibition of Bak peptide binding to human recombinant Bcl-wMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetBcl-2-like protein 2(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50013864(CHEMBL3265296)
Affinity DataKi:  4.41E+3nMAssay Description:Displacement of Flu-BID/FAM-BID from His-tagged BCLW (1 to 155) (unknown origin) expressed in Escherichia coli BL21(DE3) after 3 hrs by fluorescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetBcl-2-like protein 2(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50202271(2-[5-(phenyl(4-biphenyl)methylidene)-4-oxo-2-thiox...)
Affinity DataKi:  6.98E+3nMAssay Description:Displacement of Flu-Bak peptide from recombinant antiapoptotic Bcl-w protein by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetBcl-2-like protein 2(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50376902(CHEMBL408194)
Affinity DataKi:  7.01E+3nMAssay Description:Inhibition of Bcl-w (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetBcl-2-like protein 2(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM53290(2-[4-[(4-bromophenyl)sulfonylamino]-1-hydroxynapht...)
Affinity DataKi:  8.19E+3nMAssay Description:Displacement of Flu-BID/FAM-BID from His-tagged BCLW (1 to 155) (unknown origin) expressed in Escherichia coli BL21(DE3) after 3 hrs by fluorescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetBcl-2-like protein 2(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM53290(2-[4-[(4-bromophenyl)sulfonylamino]-1-hydroxynapht...)
Affinity DataKi:  8.19E+3nMAssay Description:Binding affinity to Bcl-W (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetBcl-2-like protein 2(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50251652(Biphenyl-4-carboxylic acid {[4-(adamantan-1-ylamin...)
Affinity DataKi:  9.43E+3nMAssay Description:Inhibition of 5-carboxyfluorescein-labeled Flu-Bak-BH3 peptide binding to Bcl-w by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBcl-2-like protein 2(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50251651(Biphenyl-4-carboxylic acid methyl-[(3-nitro-4-pipe...)
Affinity DataKi:  1.08E+4nMAssay Description:Inhibition of 5-carboxyfluorescein-labeled Flu-Bak-BH3 peptide binding to Bcl-w by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBcl-2-like protein 2(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM34194(3-chloro-1-(3,4-dichlorophenyl)-4-(4-methyl-1-pipe...)
Affinity DataKi:  1.25E+4nMAssay Description:Displacement of fluorescent-labeled BID-BH3 peptide from human BCL-W expressed in Escherichia coli BL21 (DE3) assessed as inhibition constant by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetBcl-2-like protein 2(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50251616(biphenyl-4-carboxylic acid methyl-[(3-nitro-4-thio...)
Affinity DataKi:  1.30E+4nMAssay Description:Inhibition of 5-carboxyfluorescein-labeled Flu-Bak-BH3 peptide binding to Bcl-w by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBcl-2-like protein 2(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50372176(CHEMBL272974)
Affinity DataKi:  1.37E+4nMAssay Description:Inhibition of Bak peptide binding to human recombinant Bcl-wMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetBcl-2-like protein 2(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM23223(Tash 1 | Gossypol, 4 | 7-[8-formyl-1,6,7-trihydrox...)
Affinity DataKi:  1.77E+4nMAssay Description:Displacement of Flu-Bak peptide from recombinant antiapoptotic Bcl-w protein by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetBcl-2-like protein 2(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50200960(ethyl 2-amino-6-(4-tert-butylphenyl)-4-(1-cyano-2-...)
Affinity DataKi:  2.03E+4nMAssay Description:Binding affinity to Bclw by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBcl-2-like protein 2(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50202277(Thiazolidinone core, 24 | 2-[5-(4-bromobenzylidene...)
Affinity DataKi:  2.15E+4nMAssay Description:Inhibition of Bak peptide binding to human recombinant Bcl-wMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetBcl-2-like protein 2(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50202277(Thiazolidinone core, 24 | 2-[5-(4-bromobenzylidene...)
Affinity DataKi:  2.15E+4nMAssay Description:Displacement of Flu-Bak peptide from recombinant antiapoptotic Bcl-w protein by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetBcl-2-like protein 2(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50202275(2-[5-(1-phenylbutylidene)-4-oxo-2-thioxothiazolidi...)
Affinity DataKi:  2.41E+4nMAssay Description:Displacement of Flu-Bak peptide from recombinant antiapoptotic Bcl-w protein by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetBcl-2-like protein 2(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50200964(ethyl 2-amino-6-cyclopentyl-4-(1-cyano-2-ethoxy-2-...)
Affinity DataKi:  3.08E+4nMAssay Description:Binding affinity to Bclw by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBcl-2-like protein 2(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50202283(2-[5-(4-bromobenzylidene)-4-oxo-2-thioxothiazolidi...)
Affinity DataKi:  3.12E+4nMAssay Description:Displacement of Flu-Bak peptide from recombinant antiapoptotic Bcl-w protein by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetBcl-2-like protein 2(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50013839(CHEMBL2030270)
Affinity DataKi:  3.75E+4nMAssay Description:Displacement of Flu-BID/FAM-BID from His-tagged BCLW (1 to 155) (unknown origin) expressed in Escherichia coli BL21(DE3) after 3 hrs by fluorescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetBcl-2-like protein 2(Human)
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50372173(CHEMBL404644)
Affinity DataKi:  3.92E+4nMAssay Description:Inhibition of Bak peptide binding to human recombinant Bcl-wMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
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