Compile Data Set for Download or QSAR
Report error Found 68 of ki data for polymerid = 6359,49000338
TargetCalcitonin gene-related peptide 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356281BDBM50356281(CHEMBL1910953)
Affinity DataKi:  0.0100nMAssay Description:Displacement of [125I]adrenomedullin form CGRP receptor in human SK-N-MC cell membrane by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356281BDBM50356281(CHEMBL1910953)
Affinity DataKi:  0.0100nMAssay Description:Displacement of [125I]adrenomedullin form CGRP receptor in human SK-N-MC cell membrane by competitive binding assay in the absence of MgCl2More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50184069BDBM50184069(CHEMBL207197 | N-((R)-1-((S)-6-amino-1-oxo-1-(4-(p...)
Affinity DataKi:  0.0140nMAssay Description:Displacement of [125I]adrenomedullin form CGRP receptor in human SK-N-MC cell membrane by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356282BDBM50356282(CHEMBL1910936)
Affinity DataKi:  0.0240nMAssay Description:Displacement of [125I]adrenomedullin form CGRP receptor in human SK-N-MC cell membrane by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 311886BDBM311886(US10166226, Example 1 | N-[(2R)-1-[4-(1H-imidazol-...)
Affinity DataKi:  0.0500nMAssay Description:Human CGRP receptors (consisting of CRLR and RAMP1) expressed in insect Sf21 cell membrane homogenates were re-suspended in the binding buffer (10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2019
Entry Details
US Patent

TargetCalcitonin gene-related peptide 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 312053BDBM312053(US10166226, Example 9 | 5-{1'-[(2R)-3-(7-methyl-1H...)
Affinity DataKi:  0.0500nMAssay Description:Human CGRP receptors (consisting of CRLR and RAMP1) expressed in insect Sf21 cell membrane homogenates were re-suspended in the binding buffer (10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2019
Entry Details
US Patent

TargetCalcitonin gene-related peptide 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 312050BDBM312050(US10166226, Example 6 | ethyl 5-{1'-[(2R)-3-(7-met...)
Affinity DataKi:  0.0630nMAssay Description:Human CGRP receptors (consisting of CRLR and RAMP1) expressed in insect Sf21 cell membrane homogenates were re-suspended in the binding buffer (10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2019
Entry Details
US Patent

TargetCalcitonin gene-related peptide 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 311913BDBM311913(US10166226, Example 2 | N-[(2R)-1-[4-(4-methyl-1H-...)
Affinity DataKi:  0.0790nMAssay Description:Human CGRP receptors (consisting of CRLR and RAMP1) expressed in insect Sf21 cell membrane homogenates were re-suspended in the binding buffer (10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2019
Entry Details
US Patent

TargetCalcitonin gene-related peptide 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 312002BDBM312002(US10166226, Example 4 | N-{(2R)-3-(7-methyl-1H-ind...)
Affinity DataKi:  0.100nMAssay Description:Human CGRP receptors (consisting of CRLR and RAMP1) expressed in insect Sf21 cell membrane homogenates were re-suspended in the binding buffer (10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2019
Entry Details
US Patent

TargetCalcitonin gene-related peptide 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 312052BDBM312052(US10166226, Example 8 | N-{(2R)-3-(7-methyl-1H-ind...)
Affinity DataKi:  0.100nMAssay Description:Human CGRP receptors (consisting of CRLR and RAMP1) expressed in insect Sf21 cell membrane homogenates were re-suspended in the binding buffer (10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2019
Entry Details
US Patent

TargetCalcitonin gene-related peptide 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 312049BDBM312049(US10166226, Example 5 | 4-(7-fluoro-2-oxo-1,2-dihy...)
Affinity DataKi:  0.126nMAssay Description:Human CGRP receptors (consisting of CRLR and RAMP1) expressed in insect Sf21 cell membrane homogenates were re-suspended in the binding buffer (10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2019
Entry Details
US Patent

TargetCalcitonin gene-related peptide 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 311965BDBM311965(US10166226, Example 3 | N-{(2R)-3-(7-methyl-1H-ind...)
Affinity DataKi:  0.158nMAssay Description:Human CGRP receptors (consisting of CRLR and RAMP1) expressed in insect Sf21 cell membrane homogenates were re-suspended in the binding buffer (10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2019
Entry Details
US Patent

TargetCalcitonin gene-related peptide 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 312051BDBM312051(US10166226, Example 7 | N-{(2R)-3-(7-methyl-1H-ind...)
Affinity DataKi:  0.158nMAssay Description:Human CGRP receptors (consisting of CRLR and RAMP1) expressed in insect Sf21 cell membrane homogenates were re-suspended in the binding buffer (10 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2019
Entry Details
US Patent

TargetCalcitonin gene-related peptide 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 126173BDBM126173(US8778957, 87)
Affinity DataKi:  0.340nM ΔG°:  -54.0kJ/molepH: 7.4 T: 2°CAssay Description:Cells expressing recombinant human CL receptor/RAMP1 were washed with PBS and harvested in harvest buffer containing 50 mM HEPES, 1 mM EDTA and Compl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2014
Entry Details
US Patent

TargetCalcitonin gene-related peptide 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 126176BDBM126176(US8778957, 84)
Affinity DataKi:  0.720nM ΔG°:  -52.2kJ/molepH: 7.4 T: 2°CAssay Description:Cells expressing recombinant human CL receptor/RAMP1 were washed with PBS and harvested in harvest buffer containing 50 mM HEPES, 1 mM EDTA and Compl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2014
Entry Details
US Patent

TargetCalcitonin gene-related peptide 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 126178BDBM126178(US8778957, 76)
Affinity DataKi:  0.730nM ΔG°:  -52.1kJ/molepH: 7.4 T: 2°CAssay Description:Cells expressing recombinant human CL receptor/RAMP1 were washed with PBS and harvested in harvest buffer containing 50 mM HEPES, 1 mM EDTA and Compl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2014
Entry Details
US Patent

TargetCalcitonin gene-related peptide 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 126170BDBM126170(US8778957, 3)
Affinity DataKi:  0.770nM ΔG°:  -52.0kJ/molepH: 7.4 T: 2°CAssay Description:Cells expressing recombinant human CL receptor/RAMP1 were washed with PBS and harvested in harvest buffer containing 50 mM HEPES, 1 mM EDTA and Compl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2014
Entry Details
US Patent

TargetCalcitonin gene-related peptide 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50224431BDBM50224431(N-[(3R,6S)-6-(2,3-difluorophenyl)-2-oxo-1-(2,2,2-t...)
Affinity DataKi:  0.780nMAssay Description:Displacement of [125I]adrenomedullin form CGRP receptor in human SK-N-MC cell membrane by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 126171BDBM126171(US8778957, 11)
Affinity DataKi:  1.80nM ΔG°:  -49.9kJ/molepH: 7.4 T: 2°CAssay Description:Cells expressing recombinant human CL receptor/RAMP1 were washed with PBS and harvested in harvest buffer containing 50 mM HEPES, 1 mM EDTA and Compl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2014
Entry Details
US Patent

TargetCalcitonin gene-related peptide 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 126177BDBM126177(US8778957, 88)
Affinity DataKi:  2.60nM ΔG°:  -49.0kJ/molepH: 7.4 T: 2°CAssay Description:Cells expressing recombinant human CL receptor/RAMP1 were washed with PBS and harvested in harvest buffer containing 50 mM HEPES, 1 mM EDTA and Compl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2014
Entry Details
US Patent

TargetCalcitonin gene-related peptide 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 126172BDBM126172(US8778957, 19)
Affinity DataKi:  2.90nM ΔG°:  -48.7kJ/molepH: 7.4 T: 2°CAssay Description:Cells expressing recombinant human CL receptor/RAMP1 were washed with PBS and harvested in harvest buffer containing 50 mM HEPES, 1 mM EDTA and Compl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2014
Entry Details
US Patent

TargetCalcitonin gene-related peptide 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 126172BDBM126172(US8778957, 19)
Affinity DataKi:  4.20nM ΔG°:  -47.8kJ/molepH: 7.4 T: 2°CAssay Description:Cells expressing recombinant human CL receptor/RAMP1 were washed with PBS and harvested in harvest buffer containing 50 mM HEPES, 1 mM EDTA and Compl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2014
Entry Details
US Patent

TargetCalcitonin gene-related peptide 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50000743BDBM50000743(CHEMBL525571 | h alpha-CGRP8-37 | [Thr-His-Arg-Leu...)
Affinity DataKi:  4.5nMAssay Description:Displacement of [125I]adrenomedullin form CGRP receptor in human SK-N-MC cell membrane by competitive binding assay in the absence of MgCl2More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50000743BDBM50000743(CHEMBL525571 | h alpha-CGRP8-37 | [Thr-His-Arg-Leu...)
Affinity DataKi:  5.5nMAssay Description:Displacement of [125I]adrenomedullin form CGRP receptor in human SK-N-MC cell membrane by competitive binding assay in presence of 5 mM MgCl2More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 126174BDBM126174(US8778957, 64)
Affinity DataKi:  6.60nM ΔG°:  -46.7kJ/molepH: 7.4 T: 2°CAssay Description:Cells expressing recombinant human CL receptor/RAMP1 were washed with PBS and harvested in harvest buffer containing 50 mM HEPES, 1 mM EDTA and Compl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2014
Entry Details
US Patent

TargetCalcitonin gene-related peptide 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356279BDBM50356279(CHEMBL1910937)
Affinity DataKi:  8nMAssay Description:Displacement of [125I]adrenomedullin form CGRP receptor in human SK-N-MC cell membrane by competitive binding assay in the absence of MgCl2More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356279BDBM50356279(CHEMBL1910937)
Affinity DataKi:  9nMAssay Description:Displacement of [125I]adrenomedullin form CGRP receptor in human SK-N-MC cell membrane by competitive binding assay in presence of 5 mM MgCl2More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356279BDBM50356279(CHEMBL1910937)
Affinity DataKi:  9.30nMAssay Description:Displacement of [125I]adrenomedullin form CGRP receptor in human SK-N-MC cell membrane by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 126175BDBM126175(US8778957, 95)
Affinity DataKi:  17nM ΔG°:  -44.3kJ/molepH: 7.4 T: 2°CAssay Description:Cells expressing recombinant human CL receptor/RAMP1 were washed with PBS and harvested in harvest buffer containing 50 mM HEPES, 1 mM EDTA and Compl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2014
Entry Details
US Patent

TargetCalcitonin gene-related peptide 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 126182BDBM126182(US8778957, 8)
Affinity DataKi:  35nM ΔG°:  -42.6kJ/molepH: 7.4 T: 2°CAssay Description:Cells expressing recombinant human CL receptor/RAMP1 were washed with PBS and harvested in harvest buffer containing 50 mM HEPES, 1 mM EDTA and Compl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2014
Entry Details
US Patent

TargetCalcitonin gene-related peptide 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 126179BDBM126179(US8778957, 69)
Affinity DataKi:  43nM ΔG°:  -42.0kJ/molepH: 7.4 T: 2°CAssay Description:Cells expressing recombinant human CL receptor/RAMP1 were washed with PBS and harvested in harvest buffer containing 50 mM HEPES, 1 mM EDTA and Compl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2014
Entry Details
US Patent

TargetCalcitonin gene-related peptide 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 126180BDBM126180(US8778957, 61)
Affinity DataKi:  58nM ΔG°:  -41.3kJ/molepH: 7.4 T: 2°CAssay Description:Cells expressing recombinant human CL receptor/RAMP1 were washed with PBS and harvested in harvest buffer containing 50 mM HEPES, 1 mM EDTA and Compl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2014
Entry Details
US Patent

TargetCalcitonin gene-related peptide 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 126189BDBM126189(US8778957, 209)
Affinity DataKi:  85nM ΔG°:  -40.4kJ/molepH: 7.4 T: 2°CAssay Description:Cells expressing recombinant human CL receptor/RAMP1 were washed with PBS and harvested in harvest buffer containing 50 mM HEPES, 1 mM EDTA and Compl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2014
Entry Details
US Patent

TargetCalcitonin gene-related peptide 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 126181BDBM126181(US8778957, 27)
Affinity DataKi:  150nM ΔG°:  -38.9kJ/molepH: 7.4 T: 2°CAssay Description:Cells expressing recombinant human CL receptor/RAMP1 were washed with PBS and harvested in harvest buffer containing 50 mM HEPES, 1 mM EDTA and Compl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2014
Entry Details
US Patent

TargetCalcitonin gene-related peptide 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 126190BDBM126190(US8778957, 45)
Affinity DataKi:  180nM ΔG°:  -38.5kJ/molepH: 7.4 T: 2°CAssay Description:Cells expressing recombinant human CL receptor/RAMP1 were washed with PBS and harvested in harvest buffer containing 50 mM HEPES, 1 mM EDTA and Compl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2014
Entry Details
US Patent

TargetCalcitonin gene-related peptide 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356280BDBM50356280(CHEMBL1910952)
Affinity DataKi:  710nMAssay Description:Displacement of [125I]adrenomedullin form CGRP receptor in human SK-N-MC cell membrane by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356280BDBM50356280(CHEMBL1910952)
Affinity DataKi:  840nMAssay Description:Displacement of [125I]adrenomedullin form CGRP receptor in human SK-N-MC cell membrane by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50171290BDBM50171290(SR 147778 | CHEMBL189676 | 5-(4-Bromo-phenyl)-1-(2...)
Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2012
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 126187BDBM126187(US8778957, 147)
Affinity DataKi:  1.10E+3nM ΔG°:  -34.0kJ/molepH: 7.4 T: 2°CAssay Description:Cells expressing recombinant human CL receptor/RAMP1 were washed with PBS and harvested in harvest buffer containing 50 mM HEPES, 1 mM EDTA and Compl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2014
Entry Details
US Patent

TargetCalcitonin gene-related peptide 1(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50224431BDBM50224431(N-[(3R,6S)-6-(2,3-difluorophenyl)-2-oxo-1-(2,2,2-t...)
Affinity DataKi:  1.20E+3nMAssay Description:Inhibition of rat CGRPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356294BDBM50356294(CHEMBL1910949)
Affinity DataKi:  1.70E+3nMAssay Description:Displacement of [125I]adrenomedullin form CGRP receptor in human SK-N-MC cell membrane by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 126188BDBM126188(US8778957, 184)
Affinity DataKi:  1.70E+3nM ΔG°:  -32.9kJ/molepH: 7.4 T: 2°CAssay Description:Cells expressing recombinant human CL receptor/RAMP1 were washed with PBS and harvested in harvest buffer containing 50 mM HEPES, 1 mM EDTA and Compl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2014
Entry Details
US Patent

TargetCalcitonin gene-related peptide 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356296BDBM50356296(CHEMBL1910951)
Affinity DataKi:  1.80E+3nMAssay Description:Displacement of [125I]adrenomedullin form CGRP receptor in human SK-N-MC cell membrane by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356287BDBM50356287(CHEMBL1910941)
Affinity DataKi:  1.90E+3nMAssay Description:Displacement of [125I]adrenomedullin form CGRP receptor in human SK-N-MC cell membrane by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356278BDBM50356278(CHEMBL1910947)
Affinity DataKi:  2.70E+3nMAssay Description:Displacement of [125I]adrenomedullin form CGRP receptor in human SK-N-MC cell membrane by competitive binding assay in presence of 5 mM MgCl2More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356278BDBM50356278(CHEMBL1910947)
Affinity DataKi:  3.30E+3nMAssay Description:Displacement of [125I]adrenomedullin form CGRP receptor in human SK-N-MC cell membrane by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 126183BDBM126183(US8778957, 7)
Affinity DataKi:  3.80E+3nM ΔG°:  -30.9kJ/molepH: 7.4 T: 2°CAssay Description:Cells expressing recombinant human CL receptor/RAMP1 were washed with PBS and harvested in harvest buffer containing 50 mM HEPES, 1 mM EDTA and Compl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2014
Entry Details
US Patent

TargetCalcitonin gene-related peptide 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356286BDBM50356286(CHEMBL1910940)
Affinity DataKi:  5.20E+3nMAssay Description:Displacement of [125I]adrenomedullin form CGRP receptor in human SK-N-MC cell membrane by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356280BDBM50356280(CHEMBL1910952)
Affinity DataKi:  5.60E+3nMAssay Description:Displacement of [125I]adrenomedullin form CGRP receptor in human SK-N-MC cell membrane by competitive binding assay in the absence of MgCl2More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCalcitonin gene-related peptide 1(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50356278BDBM50356278(CHEMBL1910947)
Affinity DataKi:  6.80E+3nMAssay Description:Inhibition of rat CGRPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
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