Compile Data Set for Download or QSAR
Report error Found 43 of ki data for polymerid = 6985,7322,8157,50000795,50000854
TargetBeta-glucuronidase(Escherichia coli (strain K12))
Academia Sinica

Curated by ChEMBL
LigandPNGBDBM50511223(CHEMBL4589187)
Affinity DataKi:  12nMAssay Description:Inhibition of Escherichia coli GUS pre-incubated for 5 to 30 mins before 4-methylumbelliferone beta-D-glucuronide substrate addition at pH 6.7More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBeta-glucuronidase(Bovine)
Academia Sinica

Curated by ChEMBL
LigandPNGBDBM50511223(CHEMBL4589187)
Affinity DataKi:  12nMAssay Description:Inhibition of bovine GUS pre-incubated for 5 to 30 mins before 4-methylumbelliferone beta-D-glucuronide substrate addition at pH 6.7More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetBeta-glucuronidase(Escherichia coli (strain K12))
Academia Sinica

Curated by ChEMBL
LigandPNGBDBM50511223(CHEMBL4589187)
Affinity DataKi:  34nMAssay Description:Inhibition of Escherichia coli GUS pre-incubated for 5 to 30 mins before 4-methylumbelliferone beta-D-glucuronide substrate addition at pH 5.5More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBeta-glucuronidase(Bovine)
Academia Sinica

Curated by ChEMBL
LigandPNGBDBM50511223(CHEMBL4589187)
Affinity DataKi:  48nMAssay Description:Inhibition of bovine GUS pre-incubated for 5 to 30 mins before 4-methylumbelliferone beta-D-glucuronide substrate addition at pH 4.5More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetBeta-glucuronidase(Escherichia coli (strain K12))
Academia Sinica

Curated by ChEMBL
LigandPNGBDBM50511221(CHEMBL4451253)
Affinity DataKi:  74nMAssay Description:Inhibition of Escherichia coli GUS pre-incubated for 5 to 30 mins before 4-methylumbelliferone beta-D-glucuronide substrate addition at pH 6.7More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBeta-glucuronidase(Bovine)
Academia Sinica

Curated by ChEMBL
LigandPNGBDBM50511220(CHEMBL1232598)
Affinity DataKi:  132nMAssay Description:Inhibition of bovine GUS pre-incubated for 5 to 30 mins before 4-methylumbelliferone beta-D-glucuronide substrate addition at pH 4.5More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetBeta-glucuronidase(Escherichia coli (strain K12))
Academia Sinica

Curated by ChEMBL
LigandPNGBDBM163636(3[(6,8Dimethyl2oxo1,2dihydroquinolin3 yl)methyl]1(...)
Affinity DataKi:  160nMAssay Description:Reactions were conducted similarly to the kinetic assays but the reaction consisted of 10 µL assay buffer, 5 µL inhibitor solution, 5 µL of 10 nM enz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2016
Entry Details Article
PubMed
TargetBeta-glucuronidase(Escherichia coli (strain K12))
Academia Sinica

Curated by ChEMBL
LigandPNGBDBM50511221(CHEMBL4451253)
Affinity DataKi:  182nMAssay Description:Inhibition of Escherichia coli GUS pre-incubated for 5 to 30 mins before 4-methylumbelliferone beta-D-glucuronide substrate addition at pH 5.5More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBeta-glucuronidase(Escherichia coli (strain K12))
Academia Sinica

Curated by ChEMBL
LigandPNGBDBM163637(3[(6,7Dimethyl2oxo1,2dihydroquinolin3yl)methyl]3(2...)
Affinity DataKi:  210nMAssay Description:Reactions were conducted similarly to the kinetic assays but the reaction consisted of 10 µL assay buffer, 5 µL inhibitor solution, 5 µL of 10 nM enz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBeta-glucuronidase(Escherichia coli (strain K12))
Academia Sinica

Curated by ChEMBL
LigandPNGBDBM163640(5,11Dimethyl3(piperazin1yl)8thia4,6diazatricyclo[7...)
Affinity DataKi:  220nMAssay Description:Reactions were conducted similarly to the kinetic assays but the reaction consisted of 10 µL assay buffer, 5 µL inhibitor solution, 5 µL of 10 nM enz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2016
Entry Details Article
PubMed
TargetBeta-glucuronidase(Escherichia coli (strain K12))
Academia Sinica

Curated by ChEMBL
LigandPNGBDBM50511220(CHEMBL1232598)
Affinity DataKi:  232nMAssay Description:Inhibition of Escherichia coli GUS pre-incubated for 5 to 30 mins before 4-methylumbelliferone beta-D-glucuronide substrate addition at pH 5.5More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetBeta-glucuronidase(Escherichia coli (strain K12))
Academia Sinica

Curated by ChEMBL
LigandPNGBDBM50624527(CHEMBL4128283)
Affinity DataKi:  580nMAssay Description:Non-competitive inhibition of Escherichia coli beta-glucuronidase assessed as inhibition constant using beta-PNPG as substrate incubated for 30 mins ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetBeta-glucuronidase(Escherichia coli (strain K12))
Academia Sinica

Curated by ChEMBL
LigandPNGBDBM163645(3[(6,8Dimethyl2oxo1Hquinolin3yl)methyl]3(2hydroxye...)
Affinity DataKi:  610nMAssay Description:Reactions were conducted similarly to the kinetic assays but the reaction consisted of 10 µL assay buffer, 5 µL inhibitor solution, 5 µL of 10 nM enz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2016
Entry Details Article
PubMed
TargetBeta-glucuronidase(Escherichia coli (strain K12))
Academia Sinica

Curated by ChEMBL
LigandPNGBDBM163641(1[2(3Fluorophenyl)5H,6H,7H,8Hpyrazolo[3,2b]quinazo...)
Affinity DataKi:  670nMAssay Description:Reactions were conducted similarly to the kinetic assays but the reaction consisted of 10 µL assay buffer, 5 µL inhibitor solution, 5 µL of 10 nM enz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2016
Entry Details Article
PubMed
TargetBeta-glucuronidase(Escherichia coli (strain K12))
Academia Sinica

Curated by ChEMBL
LigandPNGBDBM50624539(CHEMBL5414854)
Affinity DataKi:  670nMAssay Description:Inhibition of Escherichia coli beta-glucuronidase assessed as inhibition constant using beta-PNPG as substrate incubated for 30 mins by Lineweaver-Bu...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetBeta-glucuronidase(Escherichia coli (strain K12))
Academia Sinica

Curated by ChEMBL
LigandPNGBDBM163638(1(2Fluorophenyl)3(2hydroxyethyl)3[(6methyl2oxo1,2d...)
Affinity DataKi:  680nMAssay Description:Reactions were conducted similarly to the kinetic assays but the reaction consisted of 10 µL assay buffer, 5 µL inhibitor solution, 5 µL of 10 nM enz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2016
Entry Details Article
PubMed
TargetBeta-glucuronidase(Escherichia coli (strain K12))
Academia Sinica

Curated by ChEMBL
LigandPNGBDBM50624530(CHEMBL5434623)
Affinity DataKi:  710nMAssay Description:Inhibition of Escherichia coli beta-glucuronidase assessed as inhibition constant using beta-PNPG as substrate incubated for 30 mins by Lineweaver-Bu...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetBeta-glucuronidase(Escherichia coli (strain K12))
Academia Sinica

Curated by ChEMBL
LigandPNGBDBM50624531(CHEMBL5411616)
Affinity DataKi:  860nMAssay Description:Inhibition of Escherichia coli beta-glucuronidase assessed as inhibition constant using beta-PNPG as substrate incubated for 30 mins by Lineweaver-Bu...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetBeta-glucuronidase(Escherichia coli (strain K12))
Academia Sinica

Curated by ChEMBL
LigandPNGBDBM163643(2[4(2H1,3benzodioxol5ylmethyl)piperazin1yl]N(2,5di...)
Affinity DataKi:  960nMAssay Description:Reactions were conducted similarly to the kinetic assays but the reaction consisted of 10 µL assay buffer, 5 µL inhibitor solution, 5 µL of 10 nM enz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2016
Entry Details Article
PubMed
TargetBeta-glucuronidase(Escherichia coli (strain K12))
Academia Sinica

Curated by ChEMBL
LigandPNGBDBM50624538(CHEMBL5410696)
Affinity DataKi:  1.09E+3nMAssay Description:Inhibition of Escherichia coli beta-glucuronidase assessed as inhibition constant using beta-PNPG as substrate incubated for 30 mins by Lineweaver-Bu...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetBeta-glucuronidase(Escherichia coli (strain K12))
Academia Sinica

Curated by ChEMBL
LigandPNGBDBM50624532(CHEMBL5438984)
Affinity DataKi:  1.16E+3nMAssay Description:Inhibition of Escherichia coli beta-glucuronidase assessed as inhibition constant using beta-PNPG as substrate incubated for 30 mins by Lineweaver-Bu...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetBeta-glucuronidase(Escherichia coli (strain K12))
Academia Sinica

Curated by ChEMBL
LigandPNGBDBM50624528(CHEMBL5408407)
Affinity DataKi:  1.26E+3nMAssay Description:Non-competitive inhibition of Escherichia coli beta-glucuronidase assessed as inhibition constant using beta-PNPG as substrate incubated for 30 mins ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetBeta-glucuronidase(Escherichia coli (strain K12))
Academia Sinica

Curated by ChEMBL
LigandPNGBDBM163639(Methyl 2({[(6ethyl2oxo1,2dihydroquinolin3yl)methyl...)
Affinity DataKi:  1.40E+3nMAssay Description:Reactions were conducted similarly to the kinetic assays but the reaction consisted of 10 µL assay buffer, 5 µL inhibitor solution, 5 µL of 10 nM enz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2016
Entry Details Article
PubMed
TargetBeta-glucuronidase(Escherichia coli (strain K12))
Academia Sinica

Curated by ChEMBL
LigandPNGBDBM50624529(CHEMBL5430779)
Affinity DataKi:  1.55E+3nMAssay Description:Inhibition of Escherichia coli beta-glucuronidase assessed as inhibition constant using beta-PNPG as substrate incubated for 30 mins by Lineweaver-Bu...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetBeta-glucuronidase(Escherichia coli (strain K12))
Academia Sinica

Curated by ChEMBL
LigandPNGBDBM50624535(CHEMBL5395161)
Affinity DataKi:  1.64E+3nMAssay Description:Inhibition of Escherichia coli beta-glucuronidase assessed as inhibition constant using beta-PNPG as substrate incubated for 30 mins by Lineweaver-Bu...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetBeta-glucuronidase(Escherichia coli (strain K12))
Academia Sinica

Curated by ChEMBL
LigandPNGBDBM163642(Methyl 2amino5[(3chloro4methylphenyl)carbamoyl]4me...)
Affinity DataKi:  1.90E+3nMAssay Description:Reactions were conducted similarly to the kinetic assays but the reaction consisted of 10 µL assay buffer, 5 µL inhibitor solution, 5 µL of 10 nM enz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2016
Entry Details Article
PubMed
TargetBeta-glucuronidase(Escherichia coli (strain K12))
Academia Sinica

Curated by ChEMBL
LigandPNGBDBM163644(3[(6,8Dimethyl2oxo1Hquinolin3yl)methyl]3(2hydroxye...)
Affinity DataKi:  1.90E+3nMAssay Description:Reactions were conducted similarly to the kinetic assays but the reaction consisted of 10 µL assay buffer, 5 µL inhibitor solution, 5 µL of 10 nM enz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBeta-glucuronidase(Escherichia coli (strain K12))
Academia Sinica

Curated by ChEMBL
LigandPNGBDBM50624533(CHEMBL5439838)
Affinity DataKi:  2.66E+3nMAssay Description:Inhibition of Escherichia coli beta-glucuronidase assessed as inhibition constant using beta-PNPG as substrate incubated for 30 mins by Lineweaver-Bu...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetBeta-glucuronidase(Escherichia coli (strain K12))
Academia Sinica

Curated by ChEMBL
LigandPNGBDBM50624536(CHEMBL5407429)
Affinity DataKi:  3.47E+3nMAssay Description:Inhibition of Escherichia coli beta-glucuronidase assessed as inhibition constant using beta-PNPG as substrate incubated for 30 mins by Lineweaver-Bu...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetBeta-glucuronidase(Escherichia coli (strain K12))
Academia Sinica

Curated by ChEMBL
LigandPNGBDBM50624537(CHEMBL5399240)
Affinity DataKi:  4.27E+3nMAssay Description:Inhibition of Escherichia coli beta-glucuronidase assessed as inhibition constant using beta-PNPG as substrate incubated for 30 mins by Lineweaver-Bu...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetBeta-glucuronidase(Escherichia coli (strain K12))
Academia Sinica

Curated by ChEMBL
LigandPNGBDBM50624534(CHEMBL5417827)
Affinity DataKi:  4.43E+3nMAssay Description:Inhibition of Escherichia coli beta-glucuronidase assessed as inhibition constant using beta-PNPG as substrate incubated for 30 mins by Lineweaver-Bu...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetBeta-glucuronidase(Bovine)
Academia Sinica

Curated by ChEMBL
LigandPNGBDBM50511224(CHEMBL4589322)
Affinity DataKi:  4.87E+3nMAssay Description:Inhibition of bovine GUS pre-incubated for 5 to 30 mins before 4-methylumbelliferone beta-D-glucuronide substrate addition at pH 4.5More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetBeta-glucuronidase(Bovine)
Academia Sinica

Curated by ChEMBL
LigandPNGBDBM50511221(CHEMBL4451253)
Affinity DataKi:  5.87E+3nMAssay Description:Inhibition of bovine GUS pre-incubated for 5 to 30 mins before 4-methylumbelliferone beta-D-glucuronide substrate addition at pH 6.7More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetBeta-glucuronidase(Escherichia coli (strain K12))
Academia Sinica

Curated by ChEMBL
LigandPNGBDBM50624540(CHEMBL5429659)
Affinity DataKi:  7.32E+3nMAssay Description:Inhibition of Escherichia coli beta-glucuronidase assessed as inhibition constant using beta-PNPG as substrate incubated for 30 mins by Lineweaver-Bu...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetBeta-glucuronidase(Escherichia coli (strain K12))
Academia Sinica

Curated by ChEMBL
LigandPNGBDBM50511224(CHEMBL4589322)
Affinity DataKi:  1.58E+4nMAssay Description:Inhibition of Escherichia coli GUS pre-incubated for 5 to 30 mins before 4-methylumbelliferone beta-D-glucuronide substrate addition at pH 5.5More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetBeta-glucuronidase(Escherichia coli (strain K12))
Academia Sinica

Curated by ChEMBL
LigandPNGBDBM50511225((2S,3R,4R,5S)-3,4,5-Trihydroxypipecolic Acid | CHE...)
Affinity DataKi:  1.75E+4nMAssay Description:Inhibition of Escherichia coli GUS pre-incubated for 5 to 30 mins before 4-methylumbelliferone beta-D-glucuronide substrate addition at pH 5.5More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetBeta-glucuronidase(Bovine)
Academia Sinica

Curated by ChEMBL
LigandPNGBDBM50511225((2S,3R,4R,5S)-3,4,5-Trihydroxypipecolic Acid | CHE...)
Affinity DataKi:  2.15E+4nMAssay Description:Inhibition of bovine GUS pre-incubated for 5 to 30 mins before 4-methylumbelliferone beta-D-glucuronide substrate addition at pH 4.5More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetBeta-glucuronidase(Escherichia coli (strain K12))
Academia Sinica

Curated by ChEMBL
LigandPNGBDBM50008907(D-Saccharic Acid 1,4-Lactone)
Affinity DataKi:  3.09E+4nMAssay Description:Inhibition of Escherichia coli beta-glucuronidase assessed as inhibition constant using beta-PNPG as substrate incubated for 30 mins by Lineweaver-Bu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetBeta-glucuronidase(Bovine)
Academia Sinica

Curated by ChEMBL
LigandPNGBDBM50511221(CHEMBL4451253)
Affinity DataKi:  3.22E+4nMAssay Description:Inhibition of bovine GUS pre-incubated for 5 to 30 mins before 4-methylumbelliferone beta-D-glucuronide substrate addition at pH 4.5More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetBeta-glucuronidase(Escherichia coli (strain K12))
Academia Sinica

Curated by ChEMBL
LigandPNGBDBM50511222(CHEMBL4441158)
Affinity DataKi:  4.13E+4nMAssay Description:Inhibition of Escherichia coli GUS pre-incubated for 5 to 30 mins before 4-methylumbelliferone beta-D-glucuronide substrate addition at pH 6.7More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetBeta-glucuronidase(Escherichia coli (strain K12))
Academia Sinica

Curated by ChEMBL
LigandPNGBDBM50511222(CHEMBL4441158)
Affinity DataKi:  5.92E+4nMAssay Description:Inhibition of Escherichia coli GUS pre-incubated for 5 to 30 mins before 4-methylumbelliferone beta-D-glucuronide substrate addition at pH 5.5More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetBeta-glucuronidase(Bovine)
Academia Sinica

Curated by ChEMBL
LigandPNGBDBM50511222(CHEMBL4441158)
Affinity DataKi:  6.12E+4nMAssay Description:Inhibition of bovine GUS pre-incubated for 5 to 30 mins before 4-methylumbelliferone beta-D-glucuronide substrate addition at pH 6.7More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetBeta-glucuronidase(Bovine)
Academia Sinica

Curated by ChEMBL
LigandPNGBDBM50511222(CHEMBL4441158)
Affinity DataKi:  1.87E+5nMAssay Description:Inhibition of bovine GUS pre-incubated for 5 to 30 mins before 4-methylumbelliferone beta-D-glucuronide substrate addition at pH 4.5More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed