Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human androgen receptor african green monkey CV1 cells by cotransfection assayMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataEC50: 157nMAssay Description:In vitro antagonistic activity against human androgen receptor (hAR) expressed in CV-1 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 4.30E+3nMAssay Description:Displacement of [3H]R1881 from androgen receptor in human PC3 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 971nMAssay Description:Displacement of [3H]R1881 from androgen receptor in human LNCAP cellsMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human androgen receptor expressed in COS7 cells assessed as luciferase activity after 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at wild type Androgen receptor in human LNCaP-hr cells assessed as prostate specific antigen secretion measured after 3 days by enzy...More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at androgen receptor expressed in Cos7 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:In vitro agonistic activity against human androgen receptor (hAR) expressed in CV-1 cells; not activeMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Displacement of [3H]testosterone from androgen receptor in Sprague-Dawley rat prostate gland after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 54nMAssay Description:Displacement of [17-alpha-methyl-3H]mibolerone from androgen receptor expressed in HEK293 cells after 3 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 54nMAssay Description:Displacement of [3H]testosterone from Sprague-Dawley rat AR by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 54nMAssay Description:Displacement of [17-alpha-methyl-3H]-mibolerone from human androgen receptor expressed in HEK293 derived FreeStyle293F cells after 3 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 54nMAssay Description:Inhibition of wild type Androgen receptor (unknown origin) expressed in Freestyle293F cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 86.9nMAssay Description:Antagonist activity against pSG5-tagged human androgen receptor expressed in COS1 cells assessed as reduction in receptor-mediated transcriptional ac...More data for this Ligand-Target Pair
Affinity DataIC50: 87nMAssay Description:Displacement of [3H]R1881 from pSG5-tagged human androgen receptor expressed in COS1 cells assessed as relative binding inhibitionMore data for this Ligand-Target Pair
Affinity DataIC50: 117nMAssay Description:In vitro agonistic activity against human androgen receptor using cotransfection assay in CV-1 cells.More data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Antagonist activity at Androgen receptor (unknown origin) in African green monkey COS-1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Antagonist activity at human androgen receptor expressed in HeLa cells assessed as inhibition of dihydrotestosterone induced transcriptional activity...More data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Antagonist activity at androgen receptor expressed in HeLa cells assessed as inhibition of dihydrotestosterone-induced transcriptional activity by re...More data for this Ligand-Target Pair
Affinity DataIC50: 157nMAssay Description:Antagonistic activity against human androgen receptor (hAR) in co-transfected CV-1 cells.More data for this Ligand-Target Pair
Affinity DataIC50: 157nMAssay Description:Antagonistic activity (IC50) against human androgen receptor (hAR) in co-transfected CV-1 cellMore data for this Ligand-Target Pair
Affinity DataIC50: 162nMAssay Description:Antagonist activity at human androgen receptor african green monkey CV1 cells by cotransfection assayMore data for this Ligand-Target Pair
Affinity DataIC50: 162nMAssay Description:Antagonist activity at human androgen receptor in CV1 cells by transcriptional activation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:In vitro antagonistic activity against androgen receptor of MDA-453 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 173nMAssay Description:Antagonist activity at androgen receptor in human MDA-MB-453 cells assessed as inhibition of DHT-induced PSA expression by alkaline phosphatase repor...More data for this Ligand-Target Pair
Affinity DataIC50: 173nMAssay Description:Antagonist activity at human wild type AR expressed in human MDA-MB-435 cells by transactivation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 173nMAssay Description:Inhibition of androgen receptor in human MDA-453 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 173nMAssay Description:Inhibition of human androgen receptor of breast carcinoma MDA-453 cells in reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 173nMAssay Description:Antagonist activity at human androgen receptor in MDA453 cells by alkaline phosphatase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 190nMpH: 7.4 T: 2°CAssay Description:Androgen binding is measured using the hydroxylapatite (HAP) assay. In brief, the radioactive steroid [3H]R1881 solubilized in ethanol is diluted wit...More data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Displacement of [3H]mibolerone from human AR expressed in CHO-K1 cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Antagonist activity at human AR expressed in human HeLa cells co-transfected with MMTV-Luc-Hyg after 48 hrs by transient-luciferase reporter gene ass...More data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Displacement of [3H]mibolerone from human androgen receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Displacement of [3H]mibolerone from androgen receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 228nMAssay Description:Antagonism of test compounds for AR was measured by reporter gene assay in human embryonic kidney (HEK293) cells stably transfected with an expressio...More data for this Ligand-Target Pair
Affinity DataIC50: 232nMAssay Description:Activity at androgen receptor in human Saos2 cells assessed as IL6 repressionMore data for this Ligand-Target Pair
Affinity DataIC50: 248nMAssay Description:Antagonist activity at human androgen receptor expressed in HEK-293 cells harboring GRE-LUC and CMV-renilla luciferase assessed as inhibition of tran...More data for this Ligand-Target Pair
Affinity DataIC50: 270nMAssay Description:Antagonist activity at Androgen receptor in human LNCaP cells assessed as inhibition of Binding Function 3 (BF3) of AR measured by luciferase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 330nMAssay Description:Antagonist activity at human androgen receptor expressed in COS7 cells assessed as inhibition of DHT-induced luciferase activity after 24 hrs by repo...More data for this Ligand-Target Pair
Affinity DataIC50: 330nMAssay Description:Antagonist activity at androgen receptor expressed in Cos7 cells assessed as inhibition of dihydrotestosterone-induced luciferase activity after 24 h...More data for this Ligand-Target Pair
Affinity DataIC50: 330nMAssay Description:Antagonist activity at wild type Androgen receptor (unknown origin) expressed in human Cos-7 cells co-expressing pGL3-MMTV-luc vector assessed as luc...More data for this Ligand-Target Pair
Affinity DataIC50: 338nMAssay Description:Inhibitory concentration against human androgen receptor (AR) dependent transcriptional activity in co-transfected mammalian CV-1 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:In vitro antagonistic activity against mutant androgen receptor of LNCap cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of T877A androgen receptor of human prostate cancer cells in reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of mutant T877A Androgen receptor in human LNCaP cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Antagonist activity at wild type human AR expressed in human LNCAP cells by transactivation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 490nMAssay Description:Antagonist activity at GAL4-DBD fused rat androgen receptor expressed in UAS-bla 293 cells assessed as reduction in R1881-induced activation incubate...More data for this Ligand-Target Pair
Affinity DataIC50: 550nMAssay Description:Antagonist activity at AR in bicalutamide-resistant human LNCAP cells assessed as effect on cell proliferation after 6 daysMore data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Antagonist activity at AR in human bicalutamide-resistant LNCAP cells assessed as inhibition of cell proliferation after 6 daysMore data for this Ligand-Target Pair
Affinity DataIC50: 637nMAssay Description:Reagents and instruments: radiolabeled dihydrotestosterone (DHT-d3) and unlabelled dihydrotestosterone (DHT) purchased from Sigma-Aldrich (St. Louis,...More data for this Ligand-Target Pair
