Report error Found 3387 Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 2B'
Affinity DataAssay Description:IC50 Values were obtained from inhibition of norepinephrine uptake in MDCK-Net6 cells, stably transfected with the human NET. More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Further, the compounds of the invention may be tested in binding assays and functional activity assays by well known methods for other physiologicall...More data for this Ligand-Target Pair
Affinity DataEC50: 1.5nMAssay Description:Functional activity against human 5-hydroxytryptamine 2B receptor expressed in CHO cells using fluorometric imaging plate readerMore data for this Ligand-Target Pair
Affinity DataEC50: 22nMAssay Description:Functional activity against human 5-hydroxytryptamine 2B receptor expressed in CHO cells using fluorometric imaging plate readerMore data for this Ligand-Target Pair
Affinity DataEC50: 36nMAssay Description:Functional activity against human 5-hydroxytryptamine 2B receptor expressed in CHO cells using fluorometric imaging plate readerMore data for this Ligand-Target Pair
Affinity DataEC50: 3nMAssay Description:Functional activity against human 5-hydroxytryptamine 2B receptor expressed in CHO cells using fluorometric imaging plate readerMore data for this Ligand-Target Pair
Affinity DataEC50: 49nMAssay Description:Functional activity against human 5-hydroxytryptamine 2B receptor expressed in CHO cells using fluorometric imaging plate readerMore data for this Ligand-Target Pair
Affinity DataEC50: 31nMAssay Description:Functional activity against human 5-hydroxytryptamine 2B receptor expressed in CHO cells using fluorometric imaging plate readerMore data for this Ligand-Target Pair
Affinity DataEC50: 7.30nMAssay Description:Functional activity against human 5-hydroxytryptamine 2B receptor expressed in CHO cells using fluorometric imaging plate readerMore data for this Ligand-Target Pair
Affinity DataEC50: 10nMAssay Description:Functional activity against human 5-hydroxytryptamine 2B receptor expressed in CHO cells using fluorometric imaging plate readerMore data for this Ligand-Target Pair
Affinity DataEC50: 6.5nMAssay Description:Functional activity against human 5-hydroxytryptamine 2B receptor expressed in CHO cells using fluorometric imaging plate readerMore data for this Ligand-Target Pair
Affinity DataKd: 6.46E+3nMAssay Description:Antagonistic activity against 5-hydroxytryptamine 2B receptor obtained from rat stomach fundus preparationMore data for this Ligand-Target Pair
Affinity DataKd: 76nMAssay Description:Antagonistic against 5-hydroxytryptamine 2B receptorMore data for this Ligand-Target Pair
Affinity DataKd: 148nMAssay Description:Antagonistic against 5-hydroxytryptamine 2B receptorMore data for this Ligand-Target Pair
Affinity DataKd: 166nMAssay Description:Antagonistic activity against 5-hydroxytryptamine 2B receptor obtained from rat stomach fundus preparationMore data for this Ligand-Target Pair
Affinity DataKd: 141nMAssay Description:Antagonistic against 5-hydroxytryptamine 2B receptorMore data for this Ligand-Target Pair
Affinity DataKd: 3.63E+3nMAssay Description:Antagonistic activity against 5-hydroxytryptamine 2B receptor obtained from rat stomach fundus preparationMore data for this Ligand-Target Pair
Affinity DataKd: 135nMAssay Description:Antagonistic activity against 5-hydroxytryptamine 2B receptor obtained from rat stomach fundus preparationMore data for this Ligand-Target Pair
Affinity DataKd: 76nMAssay Description:Antagonistic against 5-hydroxytryptamine 2B receptorMore data for this Ligand-Target Pair
Affinity DataKd: 145nMAssay Description:Antagonistic activity against 5-hydroxytryptamine 2B receptor obtained from rat stomach fundus preparationMore data for this Ligand-Target Pair
Affinity DataKd: 4.27E+3nMAssay Description:The binding affinity to 5-hydroxytryptamine 2B receptor of rat fundusMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity against 5HT2B receptor assessed as inositol phosphate accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at recombinant human 5-HT2B receptor expressed in CHO K1 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at recombinant human 5-HT2B receptor expressed in CHO K1 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at recombinant human 5-HT2B receptor expressed in CHO K1 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at recombinant human 5-HT2B receptor expressed in CHO K1 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 247nMAssay Description:Agonist activity at recombinant human 5-HT2B receptor expressed in CHO K1 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.00E+3nMAssay Description:Agonist activity at recombinant human 5-HT2B receptor expressed in CHO K1 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at recombinant human 5-HT2B receptor expressed in CHO K1 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at recombinant human 5-HT2B receptor expressed in CHO K1 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at recombinant human 5-HT2B receptor expressed in CHO K1 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at recombinant human 5-HT2B receptor expressed in CHO K1 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at recombinant human 5-HT2B receptor expressed in CHO K1 cells assessed as calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 4.10nMAssay Description:Functional activity against human 5-hydroxytryptamine 2B receptor expressed in CHO cells using fluorometric imaging plate readerMore data for this Ligand-Target Pair
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at 5HT2B receptor (unknown origin) expressed in CHOK1 cells after 3 mins by calcium flux/FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 11nMAssay Description:Functional activity against human 5-hydroxytryptamine 2B receptor expressed in CHO cells using fluorometric imaging plate readerMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+3nMAssay Description:Functional activity against human 5-hydroxytryptamine 2B receptor expressed in CHO cells using fluorometric imaging plate readerMore data for this Ligand-Target Pair
Affinity DataEC50: 72nMAssay Description:Functional activity against human 5-hydroxytryptamine 2B receptor expressed in CHO cells using fluorometric imaging plate readerMore data for this Ligand-Target Pair
Affinity DataEC50: 4.30nMAssay Description:Functional activity against human 5-hydroxytryptamine 2B receptor expressed in CHO cells using fluorometric imaging plate readerMore data for this Ligand-Target Pair
Affinity DataEC50: 100nMAssay Description:Effective concentration towards 5-hydroxytryptamine 2B receptors transfected in HEK293 cells was determined by measuring [3H]phosphoinositol releaseMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Effective concentration towards 5-hydroxytryptamine 2B receptors transfected in HEK293 cells was determined by measuring [3H]phosphoinositol releaseMore data for this Ligand-Target Pair
Affinity DataEC50: 780nMAssay Description:Effective concentration towards 5-hydroxytryptamine 2B receptors transfected in HEK293 cells was determined by measuring [3H]phosphoinositol releaseMore data for this Ligand-Target Pair
Affinity DataEC50: 40nMAssay Description:Effective concentration towards 5-hydroxytryptamine 2B receptors transfected in HEK293 cells was determined by measuring [3H]phosphoinositol releaseMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Effective concentration towards 5-hydroxytryptamine 2B receptors transfected in HEK293 cells was determined by measuring [3H]phosphoinositol releaseMore data for this Ligand-Target Pair
Affinity DataEC50: 230nMAssay Description:Effective concentration towards 5-hydroxytryptamine 2B receptors transfected in HEK293 cells was determined by measuring [3H]phosphoinositol releaseMore data for this Ligand-Target Pair
Affinity DataEC50: 30nMAssay Description:Effective concentration towards 5-hydroxytryptamine 2B receptors transfected in HEK293 cells was determined by measuring [3H]phosphoinositol releaseMore data for this Ligand-Target Pair
Affinity DataEC50: >5.00E+3nMAssay Description:Effective concentration towards 5-hydroxytryptamine 2B receptors transfected in HEK293 cells was determined by measuring [3H]phosphoinositol releaseMore data for this Ligand-Target Pair
Affinity DataEC50: 1.10E+3nMAssay Description:Effective concentration towards 5-hydroxytryptamine 2B receptors transfected in HEK293 cells was determined by measuring [3H]phosphoinositol releaseMore data for this Ligand-Target Pair
Affinity DataEC50: 1.80E+3nMAssay Description:Effective concentration towards 5-hydroxytryptamine 2B receptors transfected in HEK293 cells was determined by measuring [3H]phosphoinositol releaseMore data for this Ligand-Target Pair
Affinity DataEC50: 180nMAssay Description:Effective concentration towards 5-hydroxytryptamine 2B receptors transfected in HEK293 cells was determined by measuring [3H]phosphoinositol releaseMore data for this Ligand-Target Pair
