Compile Data Set for Download or QSAR
Report error Found 196 Enz. Inhib. hit(s) with Target = 'Chymotrypsinogen B'
TargetChymotrypsinogen B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50133629(2,3-Dioxo-2,3-dihydro-indole-1-carboxylic acid ben...)
Affinity DataKoff:  253s-1Assay Description:Rate constant against alpha-chymotrypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetChymotrypsinogen B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50133629(2,3-Dioxo-2,3-dihydro-indole-1-carboxylic acid ben...)
Affinity DataKon:  0.0000400M-1s-1Assay Description:Rate constant against alpha-chymotrypsin from time dependent inhibition and reactivation dataMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetChymotrypsinogen B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50133629(2,3-Dioxo-2,3-dihydro-indole-1-carboxylic acid ben...)
Affinity DataKoff:  7.60s-1Assay Description:Rate constant against Alpha-chymotrypsin from time dependent inhibition and reactivation dataMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetChymotrypsinogen B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50133629(2,3-Dioxo-2,3-dihydro-indole-1-carboxylic acid ben...)
Affinity DataKon:  0.000948M-1s-1Assay Description:Rate constant against alpha-chymotrypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetChymotrypsinogen B(Bovine)
Nippon Steel

Curated by ChEMBL
LigandPNGBDBM50073123((S)-2-[3-(4-Cyano-benzoylamino)-2,2-dimethyl-nonan...)
Affinity DataIC50: 1.60nMAssay Description:In vitro inhibition of bovine alpha chymotrypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsinogen B(Bovine)
Nippon Steel

Curated by ChEMBL
LigandPNGBDBM50073123((S)-2-[3-(4-Cyano-benzoylamino)-2,2-dimethyl-nonan...)
Affinity DataIC50: 1.60nMAssay Description:In vitro inhibition of bovine alpha chymotrypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsinogen B(Bovine)
Nippon Steel

Curated by ChEMBL
LigandPNGBDBM50073139([2,2-dimethyl-3-(N-(4-cyanobenzoyl)aminoi)-5-pheny...)
Affinity DataIC50: 2.10nMAssay Description:In vitro inhibition of bovine alpha chymotrypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsinogen B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50073139([2,2-dimethyl-3-(N-(4-cyanobenzoyl)aminoi)-5-pheny...)
Affinity DataIC50: 2.10nMAssay Description:Inhibitory activity against bovine pancreatic alpha-chymotrypsin (alpha-CT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsinogen B(Bovine)
Nippon Steel

Curated by ChEMBL
LigandPNGBDBM50073123((S)-2-[3-(4-Cyano-benzoylamino)-2,2-dimethyl-nonan...)
Affinity DataIC50: 2.60nMAssay Description:In vitro inhibition of bovine alpha chymotrypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsinogen B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50075109(1,1-dimethyl-2-phenylcarboxamidoheptanoic anhydrid...)
Affinity DataIC50: 5.30nMAssay Description:Inhibitory activity against bovine pancreatic alpha-chymotrypsin (alpha-CT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsinogen B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50142284(2-Ethyl-1,1-dioxo-1,2,3,4,6,7-hexahydro-5,8-dioxa-...)
Affinity DataIC50: 10nMAssay Description:Inhibitory activity against chymotrypsinogen; Range 1-10 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2012
Entry Details Article
PubMed
TargetChymotrypsinogen B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50075107(1,1-dimethyl-4-phenyl-2-propylcarboxamidopentanoic...)
Affinity DataIC50: 12nMAssay Description:Inhibitory activity against bovine pancreatic alpha-chymotrypsin (alpha-CT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsinogen B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50075107(1,1-dimethyl-4-phenyl-2-propylcarboxamidopentanoic...)
Affinity DataIC50: 12nMAssay Description:Inhibitory activity against bovine pancreatic alpha-chymotrypsin (alpha-CT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsinogen B(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50437999(CHEMBL2409452)
Affinity DataIC50: 15nMAssay Description:Inhibition of human pancreatic chymotrypsin using Suc-Ala-Ala-Pro-7-amino-4-methylcoumarin as substrate by fluorescence microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetChymotrypsinogen B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50075110(2-(4-cyanophenylcarboxamido)-1,1-dimethyl-2-phenyl...)
Affinity DataIC50: 15nMAssay Description:Inhibitory activity against bovine pancreatic alpha-chymotrypsin (alpha-CT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsinogen B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50075106(1,1-dimethyl-4-phenyl-2-phenylcarboxamidopentanoic...)
Affinity DataIC50: 18nMAssay Description:Inhibitory activity against bovine pancreatic alpha-chymotrypsin (alpha-CT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsinogen B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50075106(1,1-dimethyl-4-phenyl-2-phenylcarboxamidopentanoic...)
Affinity DataIC50: 18nMAssay Description:Inhibitory activity against bovine pancreatic alpha-chymotrypsin (alpha-CT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsinogen B(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50437997(CHEMBL2409457)
Affinity DataIC50: 21nMAssay Description:Inhibition of human pancreatic chymotrypsin using Suc-Ala-Ala-Pro-7-amino-4-methylcoumarin as substrate by fluorescence microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetChymotrypsinogen B(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50438000(CHEMBL2409451)
Affinity DataIC50: 31nMAssay Description:Inhibition of human pancreatic chymotrypsin using Suc-Ala-Ala-Pro-7-amino-4-methylcoumarin as substrate by fluorescence microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetChymotrypsinogen B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50075114(1,1-dimethyl-2-phenylcarboxamidooctanoic anhydride...)
Affinity DataIC50: 31nMAssay Description:Inhibitory activity against bovine pancreatic alpha-chymotrypsin (alpha-CT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsinogen B(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50437992(CHEMBL2409445)
Affinity DataIC50: 38nMAssay Description:Inhibition of human pancreatic chymotrypsin using Suc-Ala-Ala-Pro-7-amino-4-methylcoumarin as substrate by fluorescence microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetChymotrypsinogen B(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50437998(CHEMBL2409456)
Affinity DataIC50: 40nMAssay Description:Inhibition of human pancreatic chymotrypsin using Suc-Ala-Ala-Pro-7-amino-4-methylcoumarin as substrate by fluorescence microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetChymotrypsinogen B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50075104(1,1-dimethyl-2-phenylcarboxamidononanoic anhydride...)
Affinity DataIC50: 44nMAssay Description:Inhibitory activity against bovine pancreatic alpha-chymotrypsin (alpha-CT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsinogen B(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50437996(CHEMBL2409458)
Affinity DataIC50: 46nMAssay Description:Inhibition of human pancreatic chymotrypsin using Suc-Ala-Ala-Pro-7-amino-4-methylcoumarin as substrate by fluorescence microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetChymotrypsinogen B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50075118(1,1-dimethyl-2-phenylcarboxamidohexanoic anhydride...)
Affinity DataIC50: 49nMAssay Description:Inhibitory activity against bovine pancreatic alpha-chymotrypsin (alpha-CT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsinogen B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289952(6-Dimethylamino-5-methyl-2-(1-phenyl-ethylamino)-b...)
Affinity DataIC50: 65nMAssay Description:Inhibitory concentration against human chymotrypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetChymotrypsinogen B(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50437991(CHEMBL2409450)
Affinity DataIC50: 66nMAssay Description:Inhibition of human pancreatic chymotrypsin using Suc-Ala-Ala-Pro-7-amino-4-methylcoumarin as substrate by fluorescence microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetChymotrypsinogen B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50075105(1,1-dimethyl-2-phenylcarboxamidopentanoic anhydrid...)
Affinity DataIC50: 72nMAssay Description:Inhibitory activity against bovine pancreatic alpha-chymotrypsin (alpha-CT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsinogen B(Bovine)
Nippon Steel

Curated by ChEMBL
LigandPNGBDBM50073127((S)-2-[3-(4-Cyano-benzoylamino)-2,2-dimethyl-nonan...)
Affinity DataIC50: 86nMAssay Description:In vitro inhibition of bovine alpha chymotrypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsinogen B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289954(5-Methyl-2-(1-phenyl-ethylamino)-benzo[d][1,3]oxaz...)
Affinity DataIC50: 88nMAssay Description:Inhibitory concentration against human chymotrypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetChymotrypsinogen B(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50437994(CHEMBL2409571)
Affinity DataIC50: 140nMAssay Description:Inhibition of human pancreatic chymotrypsin using Suc-Ala-Ala-Pro-7-amino-4-methylcoumarin as substrate by fluorescence microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetChymotrypsinogen B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50075113(1,1-dimethyl-2-phenylcarboxamidopropanoic anhydrid...)
Affinity DataIC50: 140nMAssay Description:Inhibitory activity against bovine pancreatic alpha-chymotrypsin (alpha-CT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsinogen B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289953(2-[1-(4-Bromo-phenyl)-ethylamino]-5-methyl-benzo[d...)
Affinity DataIC50: 140nMAssay Description:Inhibitory concentration against human chymotrypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetChymotrypsinogen B(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50437995(CHEMBL2409570)
Affinity DataIC50: 170nMAssay Description:Inhibition of human pancreatic chymotrypsin using Suc-Ala-Ala-Pro-7-amino-4-methylcoumarin as substrate by fluorescence microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetChymotrypsinogen B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289955(5-Methyl-2-(1-phenyl-ethylamino)-benzo[d][1,3]oxaz...)
Affinity DataIC50: 180nMAssay Description:Inhibitory concentration against human chymotrypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetChymotrypsinogen B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50075116(2-(4-cyanophenylcarboxamido)-1,1-dimethyl-2-(2-met...)
Affinity DataIC50: 190nMAssay Description:Inhibitory activity against bovine pancreatic alpha-chymotrypsin (alpha-CT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsinogen B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50075111(2-(4-cyanophenylcarboxamido)-2-cyclohex-3-enyl-1,1...)
Affinity DataIC50: 220nMAssay Description:Inhibitory activity against bovine pancreatic alpha-chymotrypsin (alpha-CT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsinogen B(Bovine)
Nippon Steel

Curated by ChEMBL
LigandPNGBDBM50073126((S)-2-[3-(4-Cyano-benzoylamino)-2,2-dimethyl-nonan...)
Affinity DataIC50: 230nMAssay Description:In vitro inhibition of bovine alpha chymotrypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsinogen B(Bovine)
Nippon Steel

Curated by ChEMBL
LigandPNGBDBM50073141((S)-2-[3-(4-Cyano-benzoylamino)-2,2-dimethyl-5-phe...)
Affinity DataIC50: 250nMAssay Description:In vitro inhibition of bovine alpha chymotrypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsinogen B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50075108(2-(2-chlorophenyl)-2-(4-cyanophenylcarboxamido)-1,...)
Affinity DataIC50: 250nMAssay Description:Inhibitory activity against bovine pancreatic alpha-chymotrypsin (alpha-CT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsinogen B(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50437993(CHEMBL2409575)
Affinity DataIC50: 370nMAssay Description:Inhibition of human pancreatic chymotrypsin using Suc-Ala-Ala-Pro-7-amino-4-methylcoumarin as substrate by fluorescence microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetChymotrypsinogen B2(Human)
Verseon

Curated by ChEMBL
LigandPNGBDBM162366(US9687479, 3 3-(5-[(5-chlorothiophen-2-yl)methyl]a...)
Affinity DataIC50: 380nMAssay Description:Inhibition of chymotrypsin (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetChymotrypsinogen B2(Human)
Verseon

Curated by ChEMBL
LigandPNGBDBM163407(US9687479, 278 1-[(2-methoxyphenyl)carbonyl]-3-(py...)
Affinity DataIC50: 670nMAssay Description:Inhibition of chymotrypsin (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetChymotrypsinogen B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50070440({(S)-1-[(S)-1-(1-Benzylcarbamoyl-4-oxo-azetidin-2-...)
Affinity DataIC50: 800nMAssay Description:Inhibitory activity against alpha-chymotrypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsinogen B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50075112(1,1-dimethyl-2-propylcarboxamidooctanoic anhydride...)
Affinity DataIC50: 810nMAssay Description:Inhibitory activity against bovine pancreatic alpha-chymotrypsin (alpha-CT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsinogen B(Bovine)
Nippon Steel

Curated by ChEMBL
LigandPNGBDBM50073128((S)-2-(3-tert-Butoxycarbonylamino-2,2-dimethyl-non...)
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibition of bovine alpha chymotrypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsinogen B(Bovine)
Nippon Steel

Curated by ChEMBL
LigandPNGBDBM50073125((S)-2-[3-(4-Cyano-benzoylamino)-2,2-dimethyl-nonan...)
Affinity DataIC50: 1.10E+3nMAssay Description:In vitro inhibition of bovine alpha chymotrypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsinogen B(Bovine)
Nippon Steel

Curated by ChEMBL
LigandPNGBDBM50073133((S)-2-[3-(3,5-Difluoro-benzoylamino)-2,2-dimethyl-...)
Affinity DataIC50: 1.50E+3nMAssay Description:In vitro inhibition of bovine alpha chymotrypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsinogen B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50070444((3R,4S)-3-Methyl-2-oxo-4-(pyridin-2-ylmethylsulfan...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibitory activity against alpha-chymotrypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetChymotrypsinogen B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50063719(2-Isopropylamino-5-methyl-benzo[d][1,3]oxazin-4-on...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibitory concentration against human chymotrypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

Displayed 1 to 50 (of 196 total ) | Next | Last >>
Jump to: