Compile Data Set for Download or QSAR
Report error Found 211 Enz. Inhib. hit(s) with Target = 'Cyclin-dependent kinase 6/G1/S-specific cyclin-D1 [L188C]'
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandPNGBDBM6619(3-[(9bR)-5-oxo-1H,2H,3H,5H,9bH-benzo[a]pyrrolizin-...)
Affinity DataIC50: 71nMpH: 7.4 T: 2°CAssay Description:In vitro kinase assays using synthetic peptides and purified enzymes were incubated at 30°C for 20 min in buffer that contained 50 uM ATP, and d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2005
Entry Details Article
PubMed
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandPNGBDBM472681(2-((5-(4-methylpiperazin-1- yl)pyridin-2-yl)amino)...)
Affinity DataIC50: 1.80E+3nMAssay Description:Selected compounds disclosed herein were tested in CDK4/cyclinD1, CDK2/CycA and CDK2/cyclinE kinase assays by Nanosyn (Santa Clara, Calif.) to determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2021
Entry Details
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TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandPNGBDBM472683(N-(5-(4-methylpiperazin-1- yl)pyridin-2-yl)-8',9'-...)
Affinity DataIC50: 1.80E+3nMAssay Description:Selected compounds disclosed herein were tested in CDK4/cyclinD1, CDK2/CycA and CDK2/cyclinE kinase assays by Nanosyn (Santa Clara, Calif.) to determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2021
Entry Details
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TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandPNGBDBM472682(ethyl 2-((5-(4-methylpiperazin-1- yl)pyridin-2-yl)...)
Affinity DataIC50: 3.50E+3nMAssay Description:Selected compounds disclosed herein were tested in CDK4/cyclinD1, CDK2/CycA and CDK2/cyclinE kinase assays by Nanosyn (Santa Clara, Calif.) to determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2021
Entry Details
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TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandPNGBDBM472673(10,10-dimethyl-2-((5-(4- methylpiperazin-1-yl)pyri...)
Affinity DataIC50: 3.06E+4nMAssay Description:Selected compounds disclosed herein were tested in CDK4/cyclinD1, CDK2/CycA and CDK2/cyclinE kinase assays by Nanosyn (Santa Clara, Calif.) to determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2021
Entry Details
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TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandPNGBDBM472680(2-((5-(4-methylpiperazin-1- yl)pyridin-2-yl)amino)...)
Affinity DataIC50: 5.04E+4nMAssay Description:Selected compounds disclosed herein were tested in CDK4/cyclinD1, CDK2/CycA and CDK2/cyclinE kinase assays by Nanosyn (Santa Clara, Calif.) to determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2021
Entry Details
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TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandPNGBDBM472677(2'-((5-(4-methylpiperazin-1- yl)pyridin-2-yl)amino...)
Affinity DataIC50: 7.59E+4nMAssay Description:Selected compounds disclosed herein were tested in CDK4/cyclinD1, CDK2/CycA and CDK2/cyclinE kinase assays by Nanosyn (Santa Clara, Calif.) to determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2021
Entry Details
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TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandPNGBDBM472674(10,10-dimethyl-2-((5-(4- methylpiperazin-1-yl)pyri...)
Affinity DataIC50: 1.00E+5nMAssay Description:Selected compounds disclosed herein were tested in CDK4/cyclinD1, CDK2/CycA and CDK2/cyclinE kinase assays by Nanosyn (Santa Clara, Calif.) to determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2021
Entry Details
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TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandPNGBDBM472675(2'-((5-(4-methylpiperazin-1- yl)pyridin-2-yl)amino...)
Affinity DataIC50: 1.00E+5nMAssay Description:Selected compounds disclosed herein were tested in CDK4/cyclinD1, CDK2/CycA and CDK2/cyclinE kinase assays by Nanosyn (Santa Clara, Calif.) to determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2021
Entry Details
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TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandPNGBDBM472678(2'-((5-(4-methylpiperazin-1- yl)pyridin-2-yl)amino...)
Affinity DataIC50: 1.00E+5nMAssay Description:Selected compounds disclosed herein were tested in CDK4/cyclinD1, CDK2/CycA and CDK2/cyclinE kinase assays by Nanosyn (Santa Clara, Calif.) to determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2021
Entry Details
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TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandPNGBDBM370149(US10233188, Example 37 | US10800783, Example 37 | ...)
Affinity DataKi:  0.0600nMAssay Description:The purpose of the CDK6/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
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TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandPNGBDBM370121(6-(difluoromethyl)-8-[(1R,2R)-2-hydroxy-2-methylcy...)
Affinity DataKi:  0.0800nMAssay Description:The purpose of the CDK6/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
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TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandPNGBDBM370162(US10233188, Example 50 | US10800783, Example 50 | ...)
Affinity DataKi:  0.0800nMAssay Description:The purpose of the CDK6/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
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TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandPNGBDBM370219(US10233188, Example 109 | US10233188, Example 106 ...)
Affinity DataKi:  0.110nMAssay Description:The purpose of the CDK6/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
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TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandPNGBDBM370115(4-({6-(2-hydroxyethyl)-8-[(1R,2S)-2-methylcyclopen...)
Affinity DataKi:  0.120nMAssay Description:The purpose of the CDK6/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
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TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandPNGBDBM467013((-)-6-(2,2-difluoroethyl)-8-[(1R*,2R*)-2-hydroxy-2...)
Affinity DataKi:  0.130nMAssay Description:The purpose of the CDK6/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
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TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandPNGBDBM370147(US10233188, Example 36 | US10800783, Example 36 | ...)
Affinity DataKi:  0.130nMAssay Description:The purpose of the CDK6/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
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TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandPNGBDBM370163(US10233188, Example 51 | US10800783, Example 51 | ...)
Affinity DataKi:  0.130nMAssay Description:The purpose of the CDK6/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
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TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandPNGBDBM370152(US10233188, Example 40 | US10800783, Example 40 | ...)
Affinity DataKi:  0.140nMAssay Description:The purpose of the CDK6/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
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TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandPNGBDBM370290(US10233188, Example 177 | BDBM467185)
Affinity DataKi:  0.140nMAssay Description:The purpose of the CDK6/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/17/2022
Entry Details
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TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandPNGBDBM370227(US10233188, Example 114 | US10800783, Example 114 ...)
Affinity DataKi:  0.150nMAssay Description:The purpose of the CDK6/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
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TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandPNGBDBM370325(BDBM467220 | US10233188, Example 212)
Affinity DataKi:  0.170nMAssay Description:The purpose of the CDK6/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/17/2022
Entry Details
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TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandPNGBDBM370233(US10233188, Example 120 | US10800783, Example 120 ...)
Affinity DataKi:  0.180nMAssay Description:The purpose of the CDK6/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
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TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandPNGBDBM370317(BDBM467212 | US10233188, Example 204)
Affinity DataKi:  0.180nMAssay Description:The purpose of the CDK6/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/17/2022
Entry Details
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TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandPNGBDBM370219(US10233188, Example 109 | US10233188, Example 106 ...)
Affinity DataKi:  0.190nMAssay Description:The purpose of the CDK6/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
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TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandPNGBDBM370256(US10233188, Example 143 | BDBM467151)
Affinity DataKi:  0.190nMAssay Description:The purpose of the CDK6/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/17/2022
Entry Details
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TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandPNGBDBM370229(US10233188, Example 116 | US10800783, Example 116 ...)
Affinity DataKi:  0.210nMAssay Description:The purpose of the CDK6/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
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TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandPNGBDBM370136(US10233188, Example 25 | US10800783, Example 25 | ...)
Affinity DataKi:  0.230nMAssay Description:The purpose of the CDK6/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
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TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandPNGBDBM370235(US10233188, Example 122 | US10800783, Example 122 ...)
Affinity DataKi:  0.230nMAssay Description:The purpose of the CDK6/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
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TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandPNGBDBM370164(US10233188, Example 52 | US10800783, Example 52 | ...)
Affinity DataKi:  0.240nMAssay Description:The purpose of the CDK6/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
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TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandPNGBDBM370120(6-chloro-8-[(1R,2R)-2-hydroxy-2-methylcyclopentyl]...)
Affinity DataKi:  0.25nMAssay Description:The purpose of the CDK6/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
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TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandPNGBDBM370205(US10233188, Example 92 | US10800783, Example 92 | ...)
Affinity DataKi:  0.260nMAssay Description:The purpose of the CDK6/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
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TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandPNGBDBM370261(BDBM467156 | US10233188, Example 148)
Affinity DataKi:  0.260nMAssay Description:The purpose of the CDK6/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/17/2022
Entry Details
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TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandPNGBDBM370267(US10233188, Example 154 | BDBM467162)
Affinity DataKi:  0.270nMAssay Description:The purpose of the CDK6/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/17/2022
Entry Details
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TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandPNGBDBM370223(US10233188, Example 110 | US10800783, Example 110 ...)
Affinity DataKi:  0.280nMAssay Description:The purpose of the CDK6/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
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TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandPNGBDBM370300(US10233188, Example 187 | BDBM467195)
Affinity DataKi:  0.290nMAssay Description:The purpose of the CDK6/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/17/2022
Entry Details
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TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandPNGBDBM370140(US10233188, Example 29 | US10800783, Example 29 | ...)
Affinity DataKi:  0.310nMAssay Description:The purpose of the CDK6/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
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TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandPNGBDBM370133(US10233188, Example 22 | US10800783, Example 22 | ...)
Affinity DataKi:  0.330nMAssay Description:The purpose of the CDK6/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
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TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandPNGBDBM370207(US10233188, Example 94 | US10800783, Example 94 | ...)
Affinity DataKi:  0.330nMAssay Description:The purpose of the CDK6/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
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TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandPNGBDBM370141(US10233188, Example 30 | US10800783, Example 30 | ...)
Affinity DataKi:  0.340nMAssay Description:The purpose of the CDK6/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
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TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandPNGBDBM370153(US10233188, Example 41 | US10800783, Example 41 | ...)
Affinity DataKi:  0.360nMAssay Description:The purpose of the CDK6/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
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TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandPNGBDBM370334(US10233188, Example 221 | BDBM467229)
Affinity DataKi:  0.360nMAssay Description:The purpose of the CDK6/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/17/2022
Entry Details
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TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandPNGBDBM370245(US10233188, Example 132 | US10800783, Example 132 ...)
Affinity DataKi:  0.370nMAssay Description:The purpose of the CDK6/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
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TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandPNGBDBM370254(US10233188, Example 141 | BDBM467148)
Affinity DataKi:  0.370nMAssay Description:The purpose of the CDK6/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/17/2022
Entry Details
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TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandPNGBDBM370298(US10233188, Example 185 | BDBM467193)
Affinity DataKi:  0.380nMAssay Description:The purpose of the CDK6/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/17/2022
Entry Details
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TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandPNGBDBM370145(US10233188, Example 34 | US10800783, Example 34 | ...)
Affinity DataKi:  0.420nMAssay Description:The purpose of the CDK6/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
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TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandPNGBDBM370150(US10233188, Example 38 | US10800783, Example 38 | ...)
Affinity DataKi:  0.420nMAssay Description:The purpose of the CDK6/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
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TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandPNGBDBM370243(US10233188, Example 130 | US10800783, Example 130 ...)
Affinity DataKi:  0.430nMAssay Description:The purpose of the CDK6/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
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TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandPNGBDBM370265(US10233188, Example 152 | BDBM467160)
Affinity DataKi:  0.430nMAssay Description:The purpose of the CDK6/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
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Date in BDB:
10/17/2022
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TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1 [L188C](Human)
Banyu Tsukuba Research Institute

LigandPNGBDBM467142((8-cyclopentyl-2-{[(methylsulfonyl)piperidin-4-yl]...)
Affinity DataKi:  0.440nMAssay Description:The purpose of the CDK6/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
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