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Found 4 Enz. Inhib. hit(s) with Target = 'Inosine-5-monophosphate dehydrogenase'
TargetInosine-5-monophosphate dehydrogenase(Cryptosporidium parvum)
Brandeis University

LigandPNGBDBM81328(methyl 3-methyl-2-oxo-1,2-dihydroquinoline-4-carbo...)
Affinity DataIC50:  1.60E+3nMpH: 8.0 T: 2°CAssay Description:Enzyme inhibition assay using recombinant human IMPDH1 and IMPDH2 and C.parvum were expressed in guaB strains of escherichia coli.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5-monophosphate dehydrogenase(Cryptosporidium parvum)
Brandeis University

LigandPNGBDBM50294184(CHEMBL561640 | N-(4-chlorophenyl)-2-phenoxypropana...)
Affinity DataIC50:  3.30E+3nMpH: 8.0 T: 2°CAssay Description:Enzyme inhibition assay using recombinant human IMPDH1 and IMPDH2 and C.parvum were expressed in guaB strains of escherichia coli.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5-monophosphate dehydrogenase(Cryptosporidium parvum)
Brandeis University

LigandPNGBDBM81327(Tetrahydroquinoxalin analog, J)
Affinity DataIC50:  5.90E+3nMpH: 8.0 T: 2°CAssay Description:Enzyme inhibition assay using recombinant human IMPDH1 and IMPDH2 and C.parvum were expressed in guaB strains of escherichia coli.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInosine-5-monophosphate dehydrogenase(Cryptosporidium parvum)
Brandeis University

LigandPNGBDBM81329(N-[(Z)-N-(pyridin-3-yl)carboximidoyl]-2,3-dihydro-...)
Affinity DataIC50:  1.90E+4nMpH: 8.0 T: 2°CAssay Description:Enzyme inhibition assay using recombinant human IMPDH1 and IMPDH2 and C.parvum were expressed in guaB strains of escherichia coli.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed