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Found 13 Enz. Inhib. hit(s) with Target = 'Orotidine-5'-phosphate decarboxylase'
TargetOrotidine-5'-phosphate decarboxylase(Plasmodium falciparum (malaria parasite P. falcipa...)
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM21340(6-aza-UMP | C6-Uridine Derivative, 18 | {[(2R,3S,4...)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of Plasmodium falciparum ODCase at 25 degreeC by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrotidine-5'-phosphate decarboxylase(Plasmodium falciparum (malaria parasite P. falcipa...)
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM21340(6-aza-UMP | C6-Uridine Derivative, 18 | {[(2R,3S,4...)
Affinity DataKi:  1.10E+3nM ΔG°:  -35.4kJ/molepH: 7.5 T: 2°CAssay Description:An enzyme assay method using isothermal titration calorimetry (ITC) was developed to investigate the inhibition kinetics of ODCase. Titrations were p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrotidine-5'-phosphate decarboxylase(Plasmodium falciparum (malaria parasite P. falcipa...)
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM21337(6-Azido-uridine 5-O-Monophosphate | C6-Uridine Der...)
Affinity DataKi:  2.00E+3nM ΔG°:  -33.8kJ/molepH: 7.5 T: 2°CAssay Description:An enzyme assay method using isothermal titration calorimetry (ITC) was developed to investigate the inhibition kinetics of ODCase. Titrations were p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrotidine-5'-phosphate decarboxylase(Plasmodium falciparum (malaria parasite P. falcipa...)
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM21338(6-Amino-uridine 5-O-Monophosphate | C6-Uridine Der...)
Affinity DataKi:  2.10E+3nM ΔG°:  -33.7kJ/molepH: 7.5 T: 2°CAssay Description:An enzyme assay method using isothermal titration calorimetry (ITC) was developed to investigate the inhibition kinetics of ODCase. Titrations were p...More data for this Ligand-Target Pair
TargetOrotidine-5'-phosphate decarboxylase(Plasmodium falciparum (malaria parasite P. falcipa...)
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50398698(CHEMBL2178721)
Affinity DataKi:  2.21E+4nMAssay Description:Inhibition of Plasmodium falciparum ODCase by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrotidine-5'-phosphate decarboxylase(Plasmodium vivax (malaria parasite P. vivax))
Toronto General Research Institute

LigandPNGBDBM21339(6-Methyl-uridine 5-O-Monophosphate | C6-Uridine De...)
Affinity DataKi:  2.24E+4nMpH: 7.5Assay Description:An enzyme assay method using isothermal titration calorimetry (ITC) was developed to investigate the inhibition kinetics of ODCase. Titrations were p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrotidine-5'-phosphate decarboxylase(Plasmodium falciparum (malaria parasite P. falcipa...)
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM21335(6-cyanouridine 5-monophosphate | C6-Uridine Deriva...)
Affinity DataKi:  2.60E+4nM ΔG°:  -27.2kJ/molepH: 7.5 T: 2°CAssay Description:An enzyme assay method using isothermal titration calorimetry (ITC) was developed to investigate the inhibition kinetics of ODCase. Titrations were p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrotidine-5'-phosphate decarboxylase(Plasmodium falciparum (malaria parasite P. falcipa...)
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM21339(6-Methyl-uridine 5-O-Monophosphate | C6-Uridine De...)
Affinity DataKi:  3.41E+4nM ΔG°:  -26.5kJ/molepH: 7.5 T: 2°CAssay Description:An enzyme assay method using isothermal titration calorimetry (ITC) was developed to investigate the inhibition kinetics of ODCase. Titrations were p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrotidine-5'-phosphate decarboxylase(Plasmodium vivax (malaria parasite P. vivax))
Toronto General Research Institute

LigandPNGBDBM21335(6-cyanouridine 5-monophosphate | C6-Uridine Deriva...)
Affinity DataKi:  6.20E+4nMpH: 7.5Assay Description:An enzyme assay method using isothermal titration calorimetry (ITC) was developed to investigate the inhibition kinetics of ODCase. Titrations were p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrotidine-5'-phosphate decarboxylase(Plasmodium falciparum (malaria parasite P. falcipa...)
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50398699(CHEMBL214393)
Affinity DataKi:  2.10E+5nMAssay Description:Inhibition of Plasmodium falciparum ODCase by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrotidine-5'-phosphate decarboxylase(Plasmodium falciparum (malaria parasite P. falcipa...)
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50398697(CHEMBL2178722)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibition of Plasmodium falciparum ODCase by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrotidine-5'-phosphate decarboxylase(Plasmodium falciparum (malaria parasite P. falcipa...)
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50310540(((2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)...)
Affinity DataKi: >1.00E+7nMAssay Description:Inhibition of Plasmodium falciparum ODCase by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrotidine-5'-phosphate decarboxylase(Plasmodium falciparum (malaria parasite P. falcipa...)
University Of Toronto

Curated by ChEMBL
LigandPNGBDBM50378785(CHEMBL1164065)
Affinity DataKi:  9.10E+8nM ΔG°:  -0.234kJ/moleT: 2°CAssay Description:Inhibition of Plasmodium falciparum uridine 5'-monophosphate synthase after overnight incubation at room temperature by VP-ITC microcalorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed