Found 27 Enz. Inhib. hit(s) with Target = 'Peptidoglycan-N-acetylglucosamine deacetylase' TargetPeptidoglycan-N-acetylglucosamine deacetylase(Streptococcus pneumoniae (Firmicutes))
University Of Toronto
Curated by ChEMBL
University Of Toronto
Curated by ChEMBL
Affinity DataKi: 2.90E+3nMAssay Description:Partial mixed inhibition of Streptococcus pneumoniae apo-Pgda using N,N',N\"-triacetyl chitotriose as substrate in presence of ZnCl2 by fluorescamine...More data for this Ligand-Target Pair
TargetPeptidoglycan-N-acetylglucosamine deacetylase BC_1974(Bacillus cereus (strain ATCC 14579 / DSM 31 / JCM ...)
Foundation For Research& Technology-Hellas
Curated by ChEMBL
Foundation For Research& Technology-Hellas
Curated by ChEMBL
Affinity DataKi: 8.70E+3nMAssay Description:Competitive inhibition of recombinant Bacillus cereus BC1974 expressed in Escherichia coli using varying levels of GlcNAc5 as substrate measured afte...More data for this Ligand-Target Pair
TargetPeptidoglycan-N-acetylglucosamine deacetylase BC_1960(Bacillus cereus (strain ATCC 14579 / DSM 31 / JCM ...)
Foundation For Research& Technology-Hellas
Curated by ChEMBL
Foundation For Research& Technology-Hellas
Curated by ChEMBL
Affinity DataKi: 6.60E+4nMAssay Description:Competitive inhibition of recombinant Bacillus cereus BC1960 expressed in Escherichia coli using varying levels of GlcNAc5 as substrate measured afte...More data for this Ligand-Target Pair
3D Structure (crystal)TargetPeptidoglycan-N-acetylglucosamine deacetylase(Streptococcus pneumoniae (Firmicutes))
University Of Toronto
Curated by ChEMBL
University Of Toronto
Curated by ChEMBL
Affinity DataKi: 8.00E+4nMAssay Description:Inhibition of His6-tagged Streptococcus pneumoniae Pgda C-terminal de-N-acetylase domain (232 to 431 residues) expressed in Escherichia coli BL21 (DE...More data for this Ligand-Target Pair
TargetPeptidoglycan-N-acetylglucosamine deacetylase(Streptococcus pneumoniae (Firmicutes))
University Of Toronto
Curated by ChEMBL
University Of Toronto
Curated by ChEMBL
Affinity DataKi: 8.00E+4nM ΔG°: -23.4kJ/molepH: 7.0 T: 2°CAssay Description:In a standard optimized reaction, SpPgdA was added to a microcentrifuge tube and incubated at 30 °C for 5 min. Chitotriose was added as a substrate t...More data for this Ligand-Target Pair
TargetPeptidoglycan-N-acetylglucosamine deacetylase(Streptococcus pneumoniae (Firmicutes))
University Of Toronto
Curated by ChEMBL
University Of Toronto
Curated by ChEMBL
Affinity DataKi: 1.70E+5nM ΔG°: -21.5kJ/molepH: 7.0 T: 2°CAssay Description:In a standard optimized reaction, SpPgdA was added to a microcentrifuge tube and incubated at 30 °C for 5 min. Chitotriose was added as a substrate t...More data for this Ligand-Target Pair
TargetPeptidoglycan-N-acetylglucosamine deacetylase(Streptococcus pneumoniae (Firmicutes))
University Of Toronto
Curated by ChEMBL
University Of Toronto
Curated by ChEMBL
Affinity DataKi: 2.20E+5nM ΔG°: -20.9kJ/molepH: 7.0 T: 2°CAssay Description:In a standard optimized reaction, SpPgdA was added to a microcentrifuge tube and incubated at 30 °C for 5 min. Chitotriose was added as a substrate t...More data for this Ligand-Target Pair
TargetPeptidoglycan-N-acetylglucosamine deacetylase(Streptococcus pneumoniae (Firmicutes))
University Of Toronto
Curated by ChEMBL
University Of Toronto
Curated by ChEMBL
Affinity DataKi: 5.80E+5nM ΔG°: -18.5kJ/molepH: 7.0 T: 2°CAssay Description:In a standard optimized reaction, SpPgdA was added to a microcentrifuge tube and incubated at 30 °C for 5 min. Chitotriose was added as a substrate t...More data for this Ligand-Target Pair
TargetPeptidoglycan-N-acetylglucosamine deacetylase(Streptococcus pneumoniae (Firmicutes))
University Of Toronto
Curated by ChEMBL
University Of Toronto
Curated by ChEMBL
Affinity DataKi: 5.80E+5nMAssay Description:Inhibition of His6-tagged Streptococcus pneumoniae Pgda C-terminal de-N-acetylase domain (232 to 431 residues) expressed in Escherichia coli BL21 (DE...More data for this Ligand-Target Pair
TargetPeptidoglycan-N-acetylglucosamine deacetylase(Streptococcus pneumoniae (Firmicutes))
University Of Toronto
Curated by ChEMBL
University Of Toronto
Curated by ChEMBL
Affinity DataKi: 7.20E+5nM ΔG°: -17.9kJ/molepH: 7.0 T: 2°CAssay Description:In a standard optimized reaction, SpPgdA was added to a microcentrifuge tube and incubated at 30 °C for 5 min. Chitotriose was added as a substrate t...More data for this Ligand-Target Pair
TargetPeptidoglycan-N-acetylglucosamine deacetylase(Streptococcus pneumoniae (Firmicutes))
University Of Toronto
Curated by ChEMBL
University Of Toronto
Curated by ChEMBL
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of Streptococcus pneumoniae Pgda expressed in Escherichia coli BL21 (DE3) cells transformed with pET28bSpPgdA232-431 plasmid using compoun...More data for this Ligand-Target Pair
TargetPeptidoglycan-N-acetylglucosamine deacetylase BC_1974(Bacillus cereus (strain ATCC 14579 / DSM 31 / JCM ...)
Foundation For Research& Technology-Hellas
Curated by ChEMBL
Foundation For Research& Technology-Hellas
Curated by ChEMBL
Affinity DataIC50: 4.33E+4nMAssay Description:Inhibition of recombinant Bacillus cereus BC1974 expressed in Escherichia coli using GlcNAc5 as substrate measured after 5 mins by fluorescamine base...More data for this Ligand-Target Pair
TargetPeptidoglycan-N-acetylglucosamine deacetylase BC_1960(Bacillus cereus (strain ATCC 14579 / DSM 31 / JCM ...)
Foundation For Research& Technology-Hellas
Curated by ChEMBL
Foundation For Research& Technology-Hellas
Curated by ChEMBL
Affinity DataIC50: 1.32E+5nMAssay Description:Inhibition of recombinant Bacillus cereus BC1960 expressed in Escherichia coli using GlcNAc5 as substrate measured after 10 mins by fluorescamine bas...More data for this Ligand-Target Pair
TargetPeptidoglycan-N-acetylglucosamine deacetylase(Streptococcus pneumoniae (Firmicutes))
University Of Toronto
Curated by ChEMBL
University Of Toronto
Curated by ChEMBL
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of Streptococcus pneumoniae Pgda expressed in Escherichia coli BL21 (DE3) cells transformed with pET28bSpPgdA232-431 plasmid using compoun...More data for this Ligand-Target Pair
TargetPeptidoglycan-N-acetylglucosamine deacetylase(Streptococcus pneumoniae (Firmicutes))
University Of Toronto
Curated by ChEMBL
University Of Toronto
Curated by ChEMBL
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of Streptococcus pneumoniae Pgda expressed in Escherichia coli BL21 (DE3) cells transformed with pET28bSpPgdA232-431 plasmid using compoun...More data for this Ligand-Target Pair
TargetPeptidoglycan-N-acetylglucosamine deacetylase(Streptococcus pneumoniae (Firmicutes))
University Of Toronto
Curated by ChEMBL
University Of Toronto
Curated by ChEMBL
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of Streptococcus pneumoniae Pgda expressed in Escherichia coli BL21 (DE3) cells transformed with pET28bSpPgdA232-431 plasmid using compoun...More data for this Ligand-Target Pair
TargetPeptidoglycan-N-acetylglucosamine deacetylase(Streptococcus pneumoniae (Firmicutes))
University Of Toronto
Curated by ChEMBL
University Of Toronto
Curated by ChEMBL
Affinity DataIC50: 4.90E+6nMAssay Description:Inhibition of Streptococcus pneumoniae Pgda expressed in Escherichia coli BL21 (DE3) cells transformed with pET28bSpPgdA232-431 plasmid using acetoxy...More data for this Ligand-Target Pair
TargetPeptidoglycan-N-acetylglucosamine deacetylase(Streptococcus pneumoniae (Firmicutes))
University Of Toronto
Curated by ChEMBL
University Of Toronto
Curated by ChEMBL
Affinity DataIC50: >5.00E+6nMAssay Description:Inhibition of Streptococcus pneumoniae Pgda expressed in Escherichia coli BL21 (DE3) cells transformed with pET28bSpPgdA232-431 plasmid using acetoxy...More data for this Ligand-Target Pair
TargetPeptidoglycan-N-acetylglucosamine deacetylase(Streptococcus pneumoniae (Firmicutes))
University Of Toronto
Curated by ChEMBL
University Of Toronto
Curated by ChEMBL
Affinity DataIC50: 5.00E+6nMAssay Description:Inhibition of Streptococcus pneumoniae Pgda expressed in Escherichia coli BL21 (DE3) cells transformed with pET28bSpPgdA232-431 plasmid using compoun...More data for this Ligand-Target Pair
TargetPeptidoglycan-N-acetylglucosamine deacetylase(Streptococcus pneumoniae (Firmicutes))
University Of Toronto
Curated by ChEMBL
University Of Toronto
Curated by ChEMBL
Affinity DataIC50: >5.00E+6nMAssay Description:Inhibition of Streptococcus pneumoniae Pgda expressed in Escherichia coli BL21 (DE3) cells transformed with pET28bSpPgdA232-431 plasmid using acetoxy...More data for this Ligand-Target Pair
TargetPeptidoglycan-N-acetylglucosamine deacetylase(Streptococcus pneumoniae (Firmicutes))
University Of Toronto
Curated by ChEMBL
University Of Toronto
Curated by ChEMBL
Affinity DataIC50: >5.00E+6nMAssay Description:Inhibition of Streptococcus pneumoniae Pgda expressed in Escherichia coli BL21 (DE3) cells transformed with pET28bSpPgdA232-431 plasmid using acetoxy...More data for this Ligand-Target Pair
TargetPeptidoglycan-N-acetylglucosamine deacetylase(Streptococcus pneumoniae (Firmicutes))
University Of Toronto
Curated by ChEMBL
University Of Toronto
Curated by ChEMBL
Affinity DataIC50: >5.00E+6nMAssay Description:Inhibition of Streptococcus pneumoniae Pgda expressed in Escherichia coli BL21 (DE3) cells transformed with pET28bSpPgdA232-431 plasmid using acetoxy...More data for this Ligand-Target Pair
TargetPeptidoglycan-N-acetylglucosamine deacetylase(Streptococcus pneumoniae (Firmicutes))
University Of Toronto
Curated by ChEMBL
University Of Toronto
Curated by ChEMBL
Affinity DataIC50: >8.00E+6nMAssay Description:Inhibition of Streptococcus pneumoniae Pgda expressed in Escherichia coli BL21 (DE3) cells transformed with pET28bSpPgdA232-431 plasmid using compoun...More data for this Ligand-Target Pair
TargetPeptidoglycan-N-acetylglucosamine deacetylase(Streptococcus pneumoniae (Firmicutes))
University Of Toronto
Curated by ChEMBL
University Of Toronto
Curated by ChEMBL
Affinity DataIC50: >1.00E+7nMAssay Description:Inhibition of Streptococcus pneumoniae Pgda expressed in Escherichia coli BL21 (DE3) cells transformed with pET28bSpPgdA232-431 plasmid using acetoxy...More data for this Ligand-Target Pair
TargetPeptidoglycan-N-acetylglucosamine deacetylase(Streptococcus pneumoniae (Firmicutes))
University Of Toronto
Curated by ChEMBL
University Of Toronto
Curated by ChEMBL
Affinity DataIC50: >1.00E+7nMAssay Description:Inhibition of Streptococcus pneumoniae Pgda expressed in Escherichia coli BL21 (DE3) cells transformed with pET28bSpPgdA232-431 plasmid using acetoxy...More data for this Ligand-Target Pair
TargetPeptidoglycan-N-acetylglucosamine deacetylase(Streptococcus pneumoniae (Firmicutes))
University Of Toronto
Curated by ChEMBL
University Of Toronto
Curated by ChEMBL
Affinity DataIC50: >1.00E+7nMAssay Description:Inhibition of Streptococcus pneumoniae Pgda expressed in Escherichia coli BL21 (DE3) cells transformed with pET28bSpPgdA232-431 plasmid using acetoxy...More data for this Ligand-Target Pair
TargetPeptidoglycan-N-acetylglucosamine deacetylase(Streptococcus pneumoniae (Firmicutes))
University Of Toronto
Curated by ChEMBL
University Of Toronto
Curated by ChEMBL
Affinity DataIC50: 1.10E+7nMAssay Description:Inhibition of Streptococcus pneumoniae Pgda expressed in Escherichia coli BL21 (DE3) cells transformed with pET28bSpPgdA232-431 plasmid using acetoxy...More data for this Ligand-Target Pair
