TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Intra-Cellular Therapies
Curated by ChEMBL
Intra-Cellular Therapies
Curated by ChEMBL
Affinity DataKi: 300nMAssay Description:Inhibition of recombinant full lenght human PDE7B using fluorescent labeled cAMP as substrate after 15 mins by IMAP assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Intra-Cellular Therapies
Curated by ChEMBL
Intra-Cellular Therapies
Curated by ChEMBL
Affinity DataKi: 360nMAssay Description:Inhibition of recombinant full lenght human PDE7B using fluorescent labeled cAMP as substrate after 15 mins by IMAP assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Intra-Cellular Therapies
Curated by ChEMBL
Intra-Cellular Therapies
Curated by ChEMBL
Affinity DataKi: 910nMAssay Description:Inhibition of recombinant full lenght human PDE7B using fluorescent labeled cAMP as substrate after 15 mins by IMAP assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Intra-Cellular Therapies
Curated by ChEMBL
Intra-Cellular Therapies
Curated by ChEMBL
Affinity DataKi: 1.20E+3nMAssay Description:Inhibition of recombinant full lenght human PDE7B using fluorescent labeled cAMP as substrate after 15 mins by IMAP assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Intra-Cellular Therapies
Curated by ChEMBL
Intra-Cellular Therapies
Curated by ChEMBL
Affinity DataKi: 6.10E+3nMAssay Description:Inhibition of recombinant full lenght human PDE7B using fluorescent labeled cAMP as substrate after 15 mins by IMAP assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Intra-Cellular Therapies
Curated by ChEMBL
Intra-Cellular Therapies
Curated by ChEMBL
Affinity DataIC50: 4.80nMpH: 8.0Assay Description:The assay method used was a scintillation proximity assay (SPA) (obtained from GE Healthcare, Product Code TRKQ7100), with [3H]-cGMP as the substrate...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Intra-Cellular Therapies
Curated by ChEMBL
Intra-Cellular Therapies
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Displacement of [3H]-cAMP from human recombinant PDE7BMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Intra-Cellular Therapies
Curated by ChEMBL
Intra-Cellular Therapies
Curated by ChEMBL
Affinity DataIC50: 9.27nMpH: 8.0Assay Description:The assay method used was a scintillation proximity assay (SPA) (obtained from GE Healthcare, Product Code TRKQ7100), with [3H]-cGMP as the substrate...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Intra-Cellular Therapies
Curated by ChEMBL
Intra-Cellular Therapies
Curated by ChEMBL
Affinity DataIC50: <10nMAssay Description:PDE7 inhibition was determined by an IMAP TR-FRET assay using PDE7B. The IMAP TR-FRET PDE assay was optimized for concentration of enzyme, FAM-cAMP s...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Intra-Cellular Therapies
Curated by ChEMBL
Intra-Cellular Therapies
Curated by ChEMBL
Affinity DataIC50: <10nMAssay Description:PDE7 inhibition was determined by an IMAP TR-FRET assay using PDE7B. The IMAP TR-FRET PDE assay was optimized for concentration of enzyme, FAM-cAMP s...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Intra-Cellular Therapies
Curated by ChEMBL
Intra-Cellular Therapies
Curated by ChEMBL
Affinity DataIC50: <10nMAssay Description:PDE7 inhibition was determined by an IMAP TR-FRET assay using PDE7B. The IMAP TR-FRET PDE assay was optimized for concentration of enzyme, FAM-cAMP s...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Intra-Cellular Therapies
Curated by ChEMBL
Intra-Cellular Therapies
Curated by ChEMBL
Affinity DataIC50: <10nMAssay Description:PDE7 inhibition was determined by an IMAP TR-FRET assay using PDE7B. The IMAP TR-FRET PDE assay was optimized for concentration of enzyme, FAM-cAMP s...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Intra-Cellular Therapies
Curated by ChEMBL
Intra-Cellular Therapies
Curated by ChEMBL
Affinity DataIC50: <10nMAssay Description:PDE7 inhibition was determined by an IMAP TR-FRET assay using PDE7B. The IMAP TR-FRET PDE assay was optimized for concentration of enzyme, FAM-cAMP s...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Intra-Cellular Therapies
Curated by ChEMBL
Intra-Cellular Therapies
Curated by ChEMBL
Affinity DataIC50: <10nMAssay Description:PDE7 inhibition was determined by an IMAP TR-FRET assay using PDE7B. The IMAP TR-FRET PDE assay was optimized for concentration of enzyme, FAM-cAMP s...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Intra-Cellular Therapies
Curated by ChEMBL
Intra-Cellular Therapies
Curated by ChEMBL
Affinity DataIC50: <10nMAssay Description:PDE7 inhibition was determined by an IMAP TR-FRET assay using PDE7B. The IMAP TR-FRET PDE assay was optimized for concentration of enzyme, FAM-cAMP s...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Intra-Cellular Therapies
Curated by ChEMBL
Intra-Cellular Therapies
Curated by ChEMBL
Affinity DataIC50: <10nMAssay Description:PDE7 inhibition was determined by an IMAP TR-FRET assay using PDE7B. The IMAP TR-FRET PDE assay was optimized for concentration of enzyme, FAM-cAMP s...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Intra-Cellular Therapies
Curated by ChEMBL
Intra-Cellular Therapies
Curated by ChEMBL
Affinity DataIC50: <10nMAssay Description:PDE7 inhibition was determined by an IMAP TR-FRET assay using PDE7B. The IMAP TR-FRET PDE assay was optimized for concentration of enzyme, FAM-cAMP s...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Intra-Cellular Therapies
Curated by ChEMBL
Intra-Cellular Therapies
Curated by ChEMBL
Affinity DataIC50: <10nMAssay Description:PDE7 inhibition was determined by an IMAP TR-FRET assay using PDE7B. The IMAP TR-FRET PDE assay was optimized for concentration of enzyme, FAM-cAMP s...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Intra-Cellular Therapies
Curated by ChEMBL
Intra-Cellular Therapies
Curated by ChEMBL
Affinity DataIC50: <10nMAssay Description:PDE7 inhibition was determined by an IMAP TR-FRET assay using PDE7B. The IMAP TR-FRET PDE assay was optimized for concentration of enzyme, FAM-cAMP s...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Intra-Cellular Therapies
Curated by ChEMBL
Intra-Cellular Therapies
Curated by ChEMBL
Affinity DataIC50: <10nMAssay Description:PDE7 inhibition was determined by an IMAP TR-FRET assay using PDE7B. The IMAP TR-FRET PDE assay was optimized for concentration of enzyme, FAM-cAMP s...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Intra-Cellular Therapies
Curated by ChEMBL
Intra-Cellular Therapies
Curated by ChEMBL
Affinity DataIC50: <10nMAssay Description:PDE7 inhibition was determined by an IMAP TR-FRET assay using PDE7B. The IMAP TR-FRET PDE assay was optimized for concentration of enzyme, FAM-cAMP s...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Intra-Cellular Therapies
Curated by ChEMBL
Intra-Cellular Therapies
Curated by ChEMBL
Affinity DataIC50: <10nMAssay Description:PDE7 inhibition was determined by an IMAP TR-FRET assay using PDE7B. The IMAP TR-FRET PDE assay was optimized for concentration of enzyme, FAM-cAMP s...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Intra-Cellular Therapies
Curated by ChEMBL
Intra-Cellular Therapies
Curated by ChEMBL
Affinity DataIC50: <10nMAssay Description:PDE7 inhibition was determined by an IMAP TR-FRET assay using PDE7B. The IMAP TR-FRET PDE assay was optimized for concentration of enzyme, FAM-cAMP s...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Intra-Cellular Therapies
Curated by ChEMBL
Intra-Cellular Therapies
Curated by ChEMBL
Affinity DataIC50: <10nMAssay Description:PDE7 inhibition was determined by an IMAP TR-FRET assay using PDE7B. The IMAP TR-FRET PDE assay was optimized for concentration of enzyme, FAM-cAMP s...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Intra-Cellular Therapies
Curated by ChEMBL
Intra-Cellular Therapies
Curated by ChEMBL
Affinity DataIC50: <10nMAssay Description:PDE7 inhibition was determined by an IMAP TR-FRET assay using PDE7B. The IMAP TR-FRET PDE assay was optimized for concentration of enzyme, FAM-cAMP s...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Intra-Cellular Therapies
Curated by ChEMBL
Intra-Cellular Therapies
Curated by ChEMBL
Affinity DataIC50: <10nMAssay Description:PDE7 inhibition was determined by an IMAP TR-FRET assay using PDE7B. The IMAP TR-FRET PDE assay was optimized for concentration of enzyme, FAM-cAMP s...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Intra-Cellular Therapies
Curated by ChEMBL
Intra-Cellular Therapies
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of cloned human recombinant PDE7B assessed as [3H]cAMP hydrolysis by radiometric assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Intra-Cellular Therapies
Curated by ChEMBL
Intra-Cellular Therapies
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Displacement of [3H]-cAMP from human recombinant PDE7BMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Intra-Cellular Therapies
Curated by ChEMBL
Intra-Cellular Therapies
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of cloned human recombinant PDE7B assessed as [3H]cAMP hydrolysis by radiometric assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Intra-Cellular Therapies
Curated by ChEMBL
Intra-Cellular Therapies
Curated by ChEMBL
Affinity DataIC50: 31nMAssay Description:Displacement of [3H]-cAMP from human recombinant PDE7BMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Intra-Cellular Therapies
Curated by ChEMBL
Intra-Cellular Therapies
Curated by ChEMBL
Affinity DataIC50: 41nMAssay Description:Inhibition of full length recombinant human PDE7B using 3',5'-[3H]cAMP as substrate after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Intra-Cellular Therapies
Curated by ChEMBL
Intra-Cellular Therapies
Curated by ChEMBL
Affinity DataIC50: 43nMAssay Description:Inhibition of cloned human recombinant PDE7B assessed as [3H]cAMP hydrolysis by radiometric assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Intra-Cellular Therapies
Curated by ChEMBL
Intra-Cellular Therapies
Curated by ChEMBL
Affinity DataIC50: 55nMAssay Description:PDE7 inhibition was determined by an IMAP TR-FRET assay using PDE7B. The IMAP TR-FRET PDE assay was optimized for concentration of enzyme, FAM-cAMP s...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Intra-Cellular Therapies
Curated by ChEMBL
Intra-Cellular Therapies
Curated by ChEMBL
Affinity DataIC50: 55nMAssay Description:PDE7 inhibition was determined by an IMAP TR-FRET assay using PDE7B. The IMAP TR-FRET PDE assay was optimized for concentration of enzyme, FAM-cAMP s...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Intra-Cellular Therapies
Curated by ChEMBL
Intra-Cellular Therapies
Curated by ChEMBL
Affinity DataIC50: 55nMAssay Description:PDE7 inhibition was determined by an IMAP TR-FRET assay using PDE7B. The IMAP TR-FRET PDE assay was optimized for concentration of enzyme, FAM-cAMP s...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Intra-Cellular Therapies
Curated by ChEMBL
Intra-Cellular Therapies
Curated by ChEMBL
Affinity DataIC50: 55nMAssay Description:PDE7 inhibition was determined by an IMAP TR-FRET assay using PDE7B. The IMAP TR-FRET PDE assay was optimized for concentration of enzyme, FAM-cAMP s...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Intra-Cellular Therapies
Curated by ChEMBL
Intra-Cellular Therapies
Curated by ChEMBL
Affinity DataIC50: 55nMAssay Description:PDE7 inhibition was determined by an IMAP TR-FRET assay using PDE7B. The IMAP TR-FRET PDE assay was optimized for concentration of enzyme, FAM-cAMP s...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Intra-Cellular Therapies
Curated by ChEMBL
Intra-Cellular Therapies
Curated by ChEMBL
Affinity DataIC50: 55nMAssay Description:PDE7 inhibition was determined by an IMAP TR-FRET assay using PDE7B. The IMAP TR-FRET PDE assay was optimized for concentration of enzyme, FAM-cAMP s...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Intra-Cellular Therapies
Curated by ChEMBL
Intra-Cellular Therapies
Curated by ChEMBL
Affinity DataIC50: 55nMAssay Description:PDE7 inhibition was determined by an IMAP TR-FRET assay using PDE7B. The IMAP TR-FRET PDE assay was optimized for concentration of enzyme, FAM-cAMP s...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Intra-Cellular Therapies
Curated by ChEMBL
Intra-Cellular Therapies
Curated by ChEMBL
Affinity DataIC50: 55nMAssay Description:PDE7 inhibition was determined by an IMAP TR-FRET assay using PDE7B. The IMAP TR-FRET PDE assay was optimized for concentration of enzyme, FAM-cAMP s...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Intra-Cellular Therapies
Curated by ChEMBL
Intra-Cellular Therapies
Curated by ChEMBL
Affinity DataIC50: 55nMAssay Description:PDE7 inhibition was determined by an IMAP TR-FRET assay using PDE7B. The IMAP TR-FRET PDE assay was optimized for concentration of enzyme, FAM-cAMP s...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Intra-Cellular Therapies
Curated by ChEMBL
Intra-Cellular Therapies
Curated by ChEMBL
Affinity DataIC50: 55nMAssay Description:PDE7 inhibition was determined by an IMAP TR-FRET assay using PDE7B. The IMAP TR-FRET PDE assay was optimized for concentration of enzyme, FAM-cAMP s...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Intra-Cellular Therapies
Curated by ChEMBL
Intra-Cellular Therapies
Curated by ChEMBL
Affinity DataIC50: 55nMAssay Description:PDE7 inhibition was determined by an IMAP TR-FRET assay using PDE7B. The IMAP TR-FRET PDE assay was optimized for concentration of enzyme, FAM-cAMP s...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Intra-Cellular Therapies
Curated by ChEMBL
Intra-Cellular Therapies
Curated by ChEMBL
Affinity DataIC50: 55nMAssay Description:PDE7 inhibition was determined by an IMAP TR-FRET assay using PDE7B. The IMAP TR-FRET PDE assay was optimized for concentration of enzyme, FAM-cAMP s...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Intra-Cellular Therapies
Curated by ChEMBL
Intra-Cellular Therapies
Curated by ChEMBL
Affinity DataIC50: 55nMAssay Description:PDE7 inhibition was determined by an IMAP TR-FRET assay using PDE7B. The IMAP TR-FRET PDE assay was optimized for concentration of enzyme, FAM-cAMP s...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Intra-Cellular Therapies
Curated by ChEMBL
Intra-Cellular Therapies
Curated by ChEMBL
Affinity DataIC50: 55nMAssay Description:PDE7 inhibition was determined by an IMAP TR-FRET assay using PDE7B. The IMAP TR-FRET PDE assay was optimized for concentration of enzyme, FAM-cAMP s...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Intra-Cellular Therapies
Curated by ChEMBL
Intra-Cellular Therapies
Curated by ChEMBL
Affinity DataIC50: 55nMAssay Description:PDE7 inhibition was determined by an IMAP TR-FRET assay using PDE7B. The IMAP TR-FRET PDE assay was optimized for concentration of enzyme, FAM-cAMP s...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Intra-Cellular Therapies
Curated by ChEMBL
Intra-Cellular Therapies
Curated by ChEMBL
Affinity DataIC50: 55nMAssay Description:PDE7 inhibition was determined by an IMAP TR-FRET assay using PDE7B. The IMAP TR-FRET PDE assay was optimized for concentration of enzyme, FAM-cAMP s...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Intra-Cellular Therapies
Curated by ChEMBL
Intra-Cellular Therapies
Curated by ChEMBL
Affinity DataIC50: 55nMAssay Description:PDE7 inhibition was determined by an IMAP TR-FRET assay using PDE7B. The IMAP TR-FRET PDE assay was optimized for concentration of enzyme, FAM-cAMP s...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Intra-Cellular Therapies
Curated by ChEMBL
Intra-Cellular Therapies
Curated by ChEMBL
Affinity DataIC50: 55nMAssay Description:PDE7 inhibition was determined by an IMAP TR-FRET assay using PDE7B. The IMAP TR-FRET PDE assay was optimized for concentration of enzyme, FAM-cAMP s...More data for this Ligand-Target Pair