Report error Found 649 Enz. Inhib. hit(s) with Target = 'ATP-binding cassette sub-family C member 4'
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Affinity DataKi: 4.00E+3nMAssay Description:Noncompetitive inhibition of MRP4-mediated E2-17betaG transport in human MRP4 expressing HEK293 cells by Dixon plotMore data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Affinity DataKi: 7.00E+3nMAssay Description:Noncompetitive inhibition of MRP4-mediated E2-17betaG transport in human MRP4 expressing HEK293 cells by Dixon plotMore data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:TP_TRANSPORTER: inhibition of DHEAS in membrane vesicles from MRP4-expressing Sf9 cellsMore data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Affinity DataIC50: 1.90E+3nMAssay Description:Binding affinity at NAChRs was determined by measuring the displacement of ([3H]Nic) from a preparation of rat cortical membranes.More data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:TP_TRANSPORTER: inhibition of E217betaG uptake in membrane vesicles from MRP4-expressing Sf9 cellsMore data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:TP_TRANSPORTER: inhibition of 9-(2-phosphonomethoxyethyl)adenine(PMEA) efflux (PMEA: 1 uM) in MRP4-expressing HEK293 cellsMore data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:TP_TRANSPORTER: inhibition of E217betaG uptake in membrane vesicles from MRP4-expressing Sf9 cellsMore data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of MRP4 (unknown origin)More data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Affinity DataIC50: 7.43E+3nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Affinity DataIC50: 8.08E+3nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Affinity DataIC50: 8.10E+3nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Affinity DataIC50: 8.30E+3nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Affinity DataIC50: 9.60E+3nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Affinity DataIC50: 9.80E+3nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:TP_TRANSPORTER: inhibition of E217betaG uptake in membrane vesicles from MRP4-expressing HEK-293 cellsMore data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:TP_TRANSPORTER: inhibition of 9-(2-phosphonomethoxyethyl)adenine(PMEA) efflux (PMEA: 1 uM) in MRP4-expressing HEK293 cellsMore data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:TP_TRANSPORTER: inhibition of 9-(2-phosphonomethoxyethyl)adenine(PMEA) efflux (PMEA: 1 uM) in MRP4-expressing HEK293 cellsMore data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:TP_TRANSPORTER: inhibition of E217betaG uptake in membrane vesicles from MRP4-expressing HEK-293 cellsMore data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:TP_TRANSPORTER: inhibition of E217betaG uptake in membrane vesicles from MRP4-expressing HEK-293 cellsMore data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Affinity DataIC50: 1.16E+4nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Affinity DataIC50: 1.21E+4nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Affinity DataIC50: 1.25E+4nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Affinity DataIC50: 1.35E+4nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Affinity DataIC50: 1.55E+4nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 4(Human)
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Radboud University Nijmegen Medical Centre
Curated by ChEMBL
Affinity DataIC50: 1.59E+4nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair