Report error Found 145 Enz. Inhib. hit(s) with Target = 'Acetylcholine receptor subunit alpha/beta/delta/gamma'
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Human)
Sibia Neurosciences
Curated by PDSP Ki Database
Sibia Neurosciences
Curated by PDSP Ki Database
Affinity DataEC50: 5.20E+4nMAssay Description:The compound was tested on recombinant human alpha-1-beta-1-gamma-delta cell lines of human embryonic kidney for nicotinic acetylcholine receptor ago...More data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Human)
Sibia Neurosciences
Curated by PDSP Ki Database
Sibia Neurosciences
Curated by PDSP Ki Database
Affinity DataEC50: 5.30E+4nMAssay Description:The compound was tested on recombinant human alpha-1-beta-1-gamma-delta cell lines of human embryonic kidney for nicotinic acetylcholine receptor ago...More data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Pacific electric ray)
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataEC50: 200nMAssay Description:Functional potency for nAChR subtype Alpha-1-beta-1-delta gamma (torpedo)More data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Pacific electric ray)
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataEC50: 4.11E+5nMAssay Description:Functional potency for nAChR subtype Alpha1-beta1 delta gamma (torpedo)More data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Pacific electric ray)
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataEC50: 6.00E+4nMAssay Description:Functional potency for nAChR subtype Alpha-1-beta-1-delta gamma(torpedo)More data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Pacific electric ray)
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKd: 18nMAssay Description:Compound was evaluated for the binding constant for association with nicotinic acetylcholine receptor (nAChR)More data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Pacific electric ray)
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKd: 230nMAssay Description:Compound was evaluated for the binding constant for association with nicotinic acetylcholine receptor (nAChR)More data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Pacific electric ray)
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKd: 1.80E+3nMAssay Description:Compound was evaluated for the binding constant for association with nicotinic acetylcholine receptor (nAChR)More data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Human)
Sibia Neurosciences
Curated by PDSP Ki Database
Sibia Neurosciences
Curated by PDSP Ki Database
Affinity DataEC50: >100nMAssay Description:Change in membrane potential in TE-671 cells expressing acetylcholine neuromuscular receptorsMore data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Human)
Sibia Neurosciences
Curated by PDSP Ki Database
Sibia Neurosciences
Curated by PDSP Ki Database
Affinity DataEC50: >100nMAssay Description:Change in membrane potential in TE-671 cells expressing acetylcholine neuromuscular receptorsMore data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Human)
Sibia Neurosciences
Curated by PDSP Ki Database
Sibia Neurosciences
Curated by PDSP Ki Database
Affinity DataEC50: >100nMAssay Description:Change in membrane potential in TE-671 cells expressing acetylcholine neuromuscular receptorsMore data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Human)
Sibia Neurosciences
Curated by PDSP Ki Database
Sibia Neurosciences
Curated by PDSP Ki Database
Affinity DataEC50: 45nMAssay Description:Change in membrane potential in TE-671 cells expressing acetylcholine neuromuscular receptorsMore data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Human)
Sibia Neurosciences
Curated by PDSP Ki Database
Sibia Neurosciences
Curated by PDSP Ki Database
Affinity DataEC50: >100nMAssay Description:Change in membrane potential in TE-671 cells expressing acetylcholine neuromuscular receptorsMore data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Human)
Sibia Neurosciences
Curated by PDSP Ki Database
Sibia Neurosciences
Curated by PDSP Ki Database
Affinity DataEC50: 0.0530nMAssay Description:Change in membrane potential in TE-671 cells expressing acetylcholine neuromuscular receptorsMore data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Human)
Sibia Neurosciences
Curated by PDSP Ki Database
Sibia Neurosciences
Curated by PDSP Ki Database
Affinity DataEC50: 37nMAssay Description:Change in membrane potential in TE-671 cells expressing acetylcholine neuromuscular receptorsMore data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Human)
Sibia Neurosciences
Curated by PDSP Ki Database
Sibia Neurosciences
Curated by PDSP Ki Database
Affinity DataEC50: 28nMAssay Description:Change in membrane potential in TE-671 cells expressing acetylcholine neuromuscular receptorsMore data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Human)
Sibia Neurosciences
Curated by PDSP Ki Database
Sibia Neurosciences
Curated by PDSP Ki Database
Affinity DataEC50: 11nMAssay Description:Change in membrane potential in TE-671 cells expressing acetylcholine neuromuscular receptorsMore data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Human)
Sibia Neurosciences
Curated by PDSP Ki Database
Sibia Neurosciences
Curated by PDSP Ki Database
Affinity DataEC50: >100nMAssay Description:Change in membrane potential in TE-671 cells expressing acetylcholine neuromuscular receptorsMore data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Human)
Sibia Neurosciences
Curated by PDSP Ki Database
Sibia Neurosciences
Curated by PDSP Ki Database
Affinity DataEC50: >100nMAssay Description:Change in membrane potential in TE-671 cells expressing acetylcholine neuromuscular receptorsMore data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Human)
Sibia Neurosciences
Curated by PDSP Ki Database
Sibia Neurosciences
Curated by PDSP Ki Database
Affinity DataEC50: 31nMAssay Description:Change in membrane potential in TE-671 cells expressing acetylcholine neuromuscular receptorsMore data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Pacific electric ray)
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataEC50: 3.20E+6nMAssay Description:In vitro ability to inhibit the binding of [125I]-alpha-bungarotoxin to nicotinic acetylcholine receptor on membranes prepared from the electric orga...More data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Human)
Sibia Neurosciences
Curated by PDSP Ki Database
Sibia Neurosciences
Curated by PDSP Ki Database
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at alpha1beta1gammadelta nAChR in human TE671/RD cells after 9.5 mins by 86Rb+ efflux assayMore data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Human)
Sibia Neurosciences
Curated by PDSP Ki Database
Sibia Neurosciences
Curated by PDSP Ki Database
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at alpha1beta1gammadelta nAChR in human TE671/RD cells after 9.5 mins by 86Rb+ efflux assayMore data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Human)
Sibia Neurosciences
Curated by PDSP Ki Database
Sibia Neurosciences
Curated by PDSP Ki Database
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at alpha1beta1gammadelta nAChR in human TE671/RD cells after 9.5 mins by 86Rb+ efflux assayMore data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Human)
Sibia Neurosciences
Curated by PDSP Ki Database
Sibia Neurosciences
Curated by PDSP Ki Database
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at alpha1beta1gammadelta nAChR in human TE671/RD cells after 9.5 mins by 86Rb+ efflux assayMore data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Human)
Sibia Neurosciences
Curated by PDSP Ki Database
Sibia Neurosciences
Curated by PDSP Ki Database
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at alpha1beta1gammadelta nAChR in human TE671/RD cells after 9.5 mins by 86Rb+ efflux assayMore data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Human)
Sibia Neurosciences
Curated by PDSP Ki Database
Sibia Neurosciences
Curated by PDSP Ki Database
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at alpha1beta1gammadelta nAChR in human TE671/RD cells after 9.5 mins by 86Rb+ efflux assayMore data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Human)
Sibia Neurosciences
Curated by PDSP Ki Database
Sibia Neurosciences
Curated by PDSP Ki Database
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at alpha1beta1gammadelta nAChR in human TE671/RD cells after 9.5 mins by 86Rb+ efflux assayMore data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Pacific electric ray)
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Inhibition of [3H]MCC binding to torpedo electroplax membranesMore data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Pacific electric ray)
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Inhibition of [3H]MCC binding to torpedo electroplax membranesMore data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Pacific electric ray)
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of [3H]MCC binding to torpedo electroplax membranesMore data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Pacific electric ray)
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:inhibition of (-)-[3H]nicotine binding to torpedo electroplax membranesMore data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Pacific electric ray)
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:inhibition of (-)-[3H]nicotine binding to torpedo electroplax membranesMore data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Pacific electric ray)
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:inhibition of (-)-[3H]nicotine binding to torpedo electroplax membranesMore data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Rat)
University of Montpellier
Curated by ChEMBL
University of Montpellier
Curated by ChEMBL
Affinity DataIC50: 6.60nMAssay Description:Inhibition of rat (alpha1)2betagammadelta expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced channel current respons...More data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Pacific electric ray)
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:inhibition of (-)-[3H]nicotine binding to torpedo electroplax membranesMore data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Pacific electric ray)
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:inhibition of (-)-[3H]nicotine binding to torpedo electroplax membranesMore data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Pacific electric ray)
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of [3H]MCC binding to torpedo electroplax membranesMore data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Pacific electric ray)
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of [3H]MCC binding to torpedo electroplax membranesMore data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Human)
Sibia Neurosciences
Curated by PDSP Ki Database
Sibia Neurosciences
Curated by PDSP Ki Database
Affinity DataIC50: 790nMAssay Description:Antagonist activity at human muscle-type nAChR (embryonic muscle) expressed in TE671 cells; (end value).More data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Pacific electric ray)
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 800nMAssay Description:inhibition of (-)-[3H]nicotine binding to torpedo electroplax membranesMore data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Pacific electric ray)
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of [3H]MCC binding to torpedo electroplax membranesMore data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Human)
Sibia Neurosciences
Curated by PDSP Ki Database
Sibia Neurosciences
Curated by PDSP Ki Database
Affinity DataIC50: 2.43E+3nMAssay Description:Antagonist activity at human muscle-type nAChR (embryonic muscle) expressed in TE671 cells; (end value).More data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Human)
Sibia Neurosciences
Curated by PDSP Ki Database
Sibia Neurosciences
Curated by PDSP Ki Database
Affinity DataIC50: 4.47E+3nMAssay Description:Antagonist activity at human muscle-type nAChR (embryonic muscle) expressed in TE671 cells; (end value).More data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Human)
Sibia Neurosciences
Curated by PDSP Ki Database
Sibia Neurosciences
Curated by PDSP Ki Database
Affinity DataIC50: 5.33E+3nMAssay Description:Antagonist activity at human muscle-type nAChR (embryonic muscle) expressed in TE671 cells; (end value).More data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Human)
Sibia Neurosciences
Curated by PDSP Ki Database
Sibia Neurosciences
Curated by PDSP Ki Database
Affinity DataIC50: 5.69E+3nMAssay Description:Antagonist activity at human muscle-type nAChR (embryonic muscle) expressed in TE671 cells; (end value).More data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Human)
Sibia Neurosciences
Curated by PDSP Ki Database
Sibia Neurosciences
Curated by PDSP Ki Database
Affinity DataIC50: 5.90E+3nMAssay Description:Antagonist activity at alpha-1-beta-1-gamma-delta nicotinic receptor in human TE671 cells assessed as inhibition varbamylcholine-induced radiolabeled...More data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Human)
Sibia Neurosciences
Curated by PDSP Ki Database
Sibia Neurosciences
Curated by PDSP Ki Database
Affinity DataIC50: 6.60E+3nMAssay Description:Antagonist activity at alpha-1-beta-1-gamma-delta nicotinic receptor in human TE671 cells assessed as inhibition varbamylcholine-induced radiolabeled...More data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Human)
Sibia Neurosciences
Curated by PDSP Ki Database
Sibia Neurosciences
Curated by PDSP Ki Database
Affinity DataIC50: 7.20E+3nMAssay Description:Antagonist activity at alpha-1-beta-1-gamma-delta nicotinic receptor in human TE671 cells assessed as inhibition varbamylcholine-induced radiolabeled...More data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Human)
Sibia Neurosciences
Curated by PDSP Ki Database
Sibia Neurosciences
Curated by PDSP Ki Database
Affinity DataIC50: 7.20E+3nMAssay Description:Antagonist activity at alpha-1-beta-1-gamma-delta nicotinic receptor in human TE671 cells assessed as inhibition varbamylcholine-induced radiolabeled...More data for this Ligand-Target Pair
