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Report error Found 172 Enz. Inhib. hit(s) with Target = 'Alpha-mannosidase'
TargetAlpha-mannosidase(Jack bean)
Hebei University

Curated by ChEMBL
LigandPNGBDBM50579646(CHEMBL5078012)
Affinity DataKd:  120nMAssay Description:Inhibition of jack bean alpha-mannosidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetAlpha-mannosidase(Jack bean)
Hebei University

Curated by ChEMBL
LigandPNGBDBM50579647(CHEMBL5090920)
Affinity DataKd:  17nMAssay Description:Inhibition of jack bean alpha-mannosidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetAlpha-mannosidase(Jack bean)
Hebei University

Curated by ChEMBL
LigandPNGBDBM50242271(Glyset | N-Hydroxyethyl-1-deoxynojirimycin | CHEMB...)
Affinity DataKd:  1.05E+5nMAssay Description:Inhibition of jack bean alpha-mannosidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetAlpha-mannosidase(Jack bean)
Hebei University

Curated by ChEMBL
LigandPNGBDBM50579648(CHEMBL5077606)
Affinity DataKd:  2.77E+5nMAssay Description:Inhibition of jack bean alpha-mannosidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetAlpha-mannosidase 2(Human)
Academia Sinica

US Patent
LigandPNGBDBM50016706(CHEMBL63139 | Octahydro-indolizine-1,2,8-triol | S...)
Affinity DataIC50: 40nMAssay Description:Compounds were diluted to give the final concentration of 100 μM and mixed with 4-MU-α-D-mannopyranoside as substrate and human Golgi α...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
Go to US Patent

TargetAlpha-mannosidase 2(Fruit fly)
University of Toronto

LigandPNGBDBM84871(Swainsonine derivative, 6)
Affinity DataIC50: 44nMpH: 5.75 T: 2°CAssay Description:Inhibition of dGMII was measured at pH 5.75. Determination of the IC50 values (concentrations of inhibitor at which 50% of activity remains) was car...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/14/2012
Entry Details Article
PubMed
TargetAlpha-mannosidase(Jack bean)
Hebei University

Curated by ChEMBL
LigandPNGBDBM50124579(CHEMBL3621532)
Affinity DataIC50: 56nMAssay Description:Inhibition of jack bean alpha-mannosidase using 10 mM p-nitrophenyl-alpha-D-mannopyranoside as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetAlpha-mannosidase(Jack bean)
Hebei University

Curated by ChEMBL
LigandPNGBDBM50124578(CHEMBL3621533)
Affinity DataIC50: 75nMAssay Description:Inhibition of jack bean alpha-mannosidase using 10 mM p-nitrophenyl-alpha-D-mannopyranoside as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetAlpha-mannosidase 2(Human)
Academia Sinica

US Patent
LigandPNGBDBM688735(US20240190866, Compound ACK900)
Affinity DataIC50: 100nMAssay Description:Compounds were diluted to give the final concentration of 100 μM and mixed with 4-MU-α-D-mannopyranoside as substrate and human Golgi α...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
Go to US Patent

TargetAlpha-mannosidase 2(Human)
Academia Sinica

US Patent
LigandPNGBDBM688738(US20240190866, Compound ACK903)
Affinity DataIC50: 190nMAssay Description:Compounds were diluted to give the final concentration of 100 μM and mixed with 4-MU-α-D-mannopyranoside as substrate and human Golgi α...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
Go to US Patent

TargetAlpha-mannosidase 2(Fruit fly)
University of Toronto

LigandPNGBDBM84870(Swainsonine derivative, 5)
Affinity DataIC50: 250nMpH: 5.75 T: 2°CAssay Description:Inhibition of dGMII was measured at pH 5.75. Determination of the IC50 values (concentrations of inhibitor at which 50% of activity remains) was car...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/14/2012
Entry Details Article
PubMed
TargetAlpha-mannosidase 2(Fruit fly)
University of Toronto

LigandPNGBDBM84872(Swainsonine derivative, 7)
Affinity DataIC50: 250nMpH: 5.75 T: 2°CAssay Description:Inhibition of dGMII was measured at pH 5.75. Determination of the IC50 values (concentrations of inhibitor at which 50% of activity remains) was car...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/14/2012
Entry Details Article
PubMed
TargetAlpha-mannosidase 2C1(Rat)
Csiro Division of Chemicals and Polymers

Curated by ChEMBL
LigandPNGBDBM50367914(CHEMBL1794796)
Affinity DataIC50: 500nMAssay Description:Inhibitory activity against Mannosidase in jack bean (Canavalia ensiformis)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAlpha-mannosidase 2C1(Rat)
Csiro Division of Chemicals and Polymers

Curated by ChEMBL
LigandPNGBDBM50367915(CHEMBL1794797)
Affinity DataIC50: 600nMAssay Description:Inhibitory activity against Mannosidase in jack bean (Canavalia ensiformis)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAlpha-mannosidase 2(Human)
Academia Sinica

US Patent
LigandPNGBDBM688739(US20240190866, Compound ACK904)
Affinity DataIC50: 800nMAssay Description:Compounds were diluted to give the final concentration of 100 μM and mixed with 4-MU-α-D-mannopyranoside as substrate and human Golgi α...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
Go to US Patent

TargetAlpha-mannosidase 2(Human)
Academia Sinica

US Patent
LigandPNGBDBM688736(US20240190866, Compound ACK901)
Affinity DataIC50: 1.00E+3nMAssay Description:Compounds were diluted to give the final concentration of 100 μM and mixed with 4-MU-α-D-mannopyranoside as substrate and human Golgi α...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
Go to US Patent

TargetAlpha-mannosidase(Jack bean)
Hebei University

Curated by ChEMBL
LigandPNGBDBM50124580(CHEMBL3621530)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of jack bean alpha-mannosidase using 10 mM p-nitrophenyl-alpha-D-mannopyranoside as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2016
Entry Details Article
PubMed
TargetAlpha-mannosidase 2(Human)
Academia Sinica

US Patent
LigandPNGBDBM688740(US20240190866, Compound ACK905)
Affinity DataIC50: 1.30E+3nMAssay Description:Compounds were diluted to give the final concentration of 100 μM and mixed with 4-MU-α-D-mannopyranoside as substrate and human Golgi α...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
Go to US Patent

TargetAlpha-mannosidase 2(Human)
Academia Sinica

US Patent
LigandPNGBDBM688737(US20240190866, Compound ACK902)
Affinity DataIC50: 1.60E+3nMAssay Description:Compounds were diluted to give the final concentration of 100 μM and mixed with 4-MU-α-D-mannopyranoside as substrate and human Golgi α...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
Go to US Patent

TargetAlpha-mannosidase 2C1(Rat)
Csiro Division of Chemicals and Polymers

Curated by ChEMBL
LigandPNGBDBM50016706(CHEMBL63139 | Octahydro-indolizine-1,2,8-triol | S...)
Affinity DataIC50: 1.75E+3nMAssay Description:Inhibitory activity against Mannosidase in jack bean (Canavalia ensiformis)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2012
Entry Details Article
PubMed
TargetAlpha-mannosidase(Jack bean)
Hebei University

Curated by ChEMBL
LigandPNGBDBM50551001(CHEMBL4745549)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of jack bean alpha-mannosidase using PNPG as substrate incubated for 10 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetAlpha-mannosidase(Jack bean)
Hebei University

Curated by ChEMBL
LigandPNGBDBM50071931(CHEMBL3407639)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of jack bean alpha-mannosidase using PNPG as substrate incubated for 10 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetAlpha-mannosidase(Jack bean)
Hebei University

Curated by ChEMBL
LigandPNGBDBM50550995(L-RADICAMINE A)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of jack bean alpha-mannosidase using PNPG as substrate incubated for 10 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetAlpha-mannosidase(Jack bean)
Hebei University

Curated by ChEMBL
LigandPNGBDBM50550996(CHEMBL4783560)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of jack bean alpha-mannosidase using PNPG as substrate incubated for 10 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetAlpha-mannosidase(Jack bean)
Hebei University

Curated by ChEMBL
LigandPNGBDBM50550998(CHEMBL4788384)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of jack bean alpha-mannosidase using PNPG as substrate incubated for 10 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetAlpha-mannosidase(Jack bean)
Hebei University

Curated by ChEMBL
LigandPNGBDBM50550999(CHEMBL4796653)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of jack bean alpha-mannosidase using PNPG as substrate incubated for 10 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetAlpha-mannosidase(Jack bean)
Hebei University

Curated by ChEMBL
LigandPNGBDBM50551000(CHEMBL4751456)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of jack bean alpha-mannosidase using PNPG as substrate incubated for 10 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetAlpha-mannosidase(Jack bean)
Hebei University

Curated by ChEMBL
LigandPNGBDBM50341204((Z)-3-butylidenephthalide | CHEMBL1765390)
Affinity DataIC50: 4.10E+4nMAssay Description:Inhibition of jack bean alpha-mannosidase using PNPG as substrate incubated for 10 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetAlpha-mannosidase(Jack bean)
Hebei University

Curated by ChEMBL
LigandPNGBDBM50551006(CHEMBL4800248)
Affinity DataIC50: 4.12E+4nMAssay Description:Inhibition of jack bean alpha-mannosidase using PNPG as substrate incubated for 10 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetAlpha-mannosidase 2(Rat)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50016703(CHEMBL80254 | Imino-D-Arabinitol | BDBM50031485 | ...)
Affinity DataIC50: 4.60E+4nMAssay Description:Inhibition of golgi Alpha-mannosidase II in rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-mannosidase(Jack bean)
Hebei University

Curated by ChEMBL
LigandPNGBDBM19459(Prunetol | Genisteol | CHEMBL44 | US8552057, 2 | c...)
Affinity DataIC50: 4.90E+4nMAssay Description:Inhibition of jack bean alpha-mannosidase using PNPG as substrate incubated for 10 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetAlpha-mannosidase(Jack bean)
Hebei University

Curated by ChEMBL
LigandPNGBDBM24783(4H-chromen-4-one | chromone, 12)
Affinity DataIC50: 4.90E+4nMAssay Description:Inhibition of jack bean alpha-mannosidase using PNPG as substrate incubated for 10 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetAlpha-mannosidase 2(Rat)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM18351((2R,3R,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-tr...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of golgi Alpha-mannosidase II in rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-mannosidase 2C1(Rat)
Csiro Division of Chemicals and Polymers

Curated by ChEMBL
LigandPNGBDBM18355(N-Butyl-DNJ | (2R,3R,4R,5S)-1-butyl-2-(hydroxymeth...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of soluble Alpha-mannosidase II in rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-mannosidase 2C1(Rat)
Csiro Division of Chemicals and Polymers

Curated by ChEMBL
LigandPNGBDBM50031484((2R,3R,4R)-1-Butyl-2-hydroxymethyl-pyrrolidine-3,4...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of soluble Alpha-mannosidase II in rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-mannosidase(Rat)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50031484((2R,3R,4R)-1-Butyl-2-hydroxymethyl-pyrrolidine-3,4...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of lysosomal Alpha-mannosidase II in rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-mannosidase(Rat)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM18355(N-Butyl-DNJ | (2R,3R,4R,5S)-1-butyl-2-(hydroxymeth...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of lysosomal Alpha-mannosidase II in rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-mannosidase 2C1(Rat)
Csiro Division of Chemicals and Polymers

Curated by ChEMBL
LigandPNGBDBM18351((2R,3R,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-tr...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of soluble Alpha-mannosidase II in rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-mannosidase 2(Rat)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM18353((2R,3R,4R,5S)-2-(hydroxymethyl)-1-methylpiperidine...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of golgi Alpha-mannosidase II in rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-mannosidase 2(Rat)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50031481(2(R),5(R)-bis(hydroxymethyl)-3(R),4(R)-dihydroxypy...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of golgi Alpha-mannosidase II in rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-mannosidase 2(Rat)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50031482((2R,3R,4R,5R)-1-Butyl-2,5-bis-hydroxymethyl-pyrrol...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of golgi Alpha-mannosidase II in rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-mannosidase 2(Rat)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50031483((2R,3R,4R,5R)-2,5-Bis-hydroxymethyl-1-methyl-pyrro...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of golgi Alpha-mannosidase II in rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-mannosidase 2C1(Rat)
Csiro Division of Chemicals and Polymers

Curated by ChEMBL
LigandPNGBDBM50016703(CHEMBL80254 | Imino-D-Arabinitol | BDBM50031485 | ...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of soluble Alpha-mannosidase II in rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-mannosidase(Rat)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50031481(2(R),5(R)-bis(hydroxymethyl)-3(R),4(R)-dihydroxypy...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of lysosomal Alpha-mannosidase II in rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-mannosidase 2C1(Rat)
Csiro Division of Chemicals and Polymers

Curated by ChEMBL
LigandPNGBDBM50031480((2R,3R,4R)-2-Hydroxymethyl-1-methyl-pyrrolidine-3,...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of soluble Alpha-mannosidase II in rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-mannosidase(Rat)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50031483((2R,3R,4R,5R)-2,5-Bis-hydroxymethyl-1-methyl-pyrro...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of lysosomal Alpha-mannosidase II in rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-mannosidase(Rat)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50031482((2R,3R,4R,5R)-1-Butyl-2,5-bis-hydroxymethyl-pyrrol...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of lysosomal Alpha-mannosidase II in rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-mannosidase 2(Rat)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM18355(N-Butyl-DNJ | (2R,3R,4R,5S)-1-butyl-2-(hydroxymeth...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of golgi Alpha-mannosidase II in rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-mannosidase(Jack bean)
Hebei University

Curated by ChEMBL
LigandPNGBDBM92460(Casuarine)
Affinity DataIC50: 5.10E+4nMAssay Description:Inhibition of jack bean alpha-mannosidase using PNPG as substrate incubated for 10 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetAlpha-mannosidase(Jack bean)
Hebei University

Curated by ChEMBL
LigandPNGBDBM50551004(CHEMBL4758678)
Affinity DataIC50: 6.14E+4nMAssay Description:Inhibition of jack bean alpha-mannosidase using PNPG as substrate incubated for 10 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
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