Compile Data Set for Download or QSAR
Report error Found 7011 Enz. Inhib. hit(s) with Target = 'Androgen Receptor'
TargetAndrogen receptor(Human)
St. Jude Research Hospital

LigandPNGBDBM35910(flufenamic acid analogue, 36)
Affinity DataEC50:  3.00E+4nMpH: 7.2 T: 2°CAssay Description:AR functionality was determined by fluorescence polarization (excitation @485 nm, emission @ 530 nm) assay, which measures fluorescently labeled SRC2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
St. Jude Research Hospital

LigandPNGBDBM35911(flufenamic acid analogue, 37)
Affinity DataEC50:  3.90E+4nMpH: 7.2 T: 2°CAssay Description:AR functionality was determined by fluorescence polarization (excitation @485 nm, emission @ 530 nm) assay, which measures fluorescently labeled SRC2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
St. Jude Research Hospital

LigandPNGBDBM35912(flufenamic acid analogue, 38)
Affinity DataEC50:  4.25E+4nMpH: 7.2 T: 2°CAssay Description:AR functionality was determined by fluorescence polarization (excitation @485 nm, emission @ 530 nm) assay, which measures fluorescently labeled SRC2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
St. Jude Research Hospital

LigandPNGBDBM35913(flufenamic acid analogue, 39)
Affinity DataEC50:  4.85E+4nMpH: 7.2 T: 2°CAssay Description:AR functionality was determined by fluorescence polarization (excitation @485 nm, emission @ 530 nm) assay, which measures fluorescently labeled SRC2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
St. Jude Research Hospital

LigandPNGBDBM35914(flufenamic acid analogue, 40)
Affinity DataEC50:  5.40E+4nMAssay Description:A radiolabeled ligand competition scintillation proximity assay (SPA) for the androgen receptor (AR) using Ni-coated 384-well FlashPlates. It measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
St. Jude Research Hospital

LigandPNGBDBM35908(flufenamic acid analogue, 41 | flufenamic acid ana...)
Affinity DataEC50:  5.60E+4nMAssay Description:A radiolabeled ligand competition scintillation proximity assay (SPA) for the androgen receptor (AR) using Ni-coated 384-well FlashPlates. It measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
St. Jude Research Hospital

LigandPNGBDBM35916(flufenamic acid analogue, 42)
Affinity DataEC50:  6.40E+4nMAssay Description:A radiolabeled ligand competition scintillation proximity assay (SPA) for the androgen receptor (AR) using Ni-coated 384-well FlashPlates. It measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
St. Jude Research Hospital

LigandPNGBDBM35917(flufenamic acid analogue, 43)
Affinity DataEC50:  7.55E+4nMAssay Description:A radiolabeled ligand competition scintillation proximity assay (SPA) for the androgen receptor (AR) using Ni-coated 384-well FlashPlates. It measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
St. Jude Research Hospital

LigandPNGBDBM35918(flufenamic acid analogue, 44)
Affinity DataEC50:  8.30E+4nMAssay Description:A radiolabeled ligand competition scintillation proximity assay (SPA) for the androgen receptor (AR) using Ni-coated 384-well FlashPlates. It measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
St. Jude Research Hospital

LigandPNGBDBM35919(flufenamic acid analogue, 45)
Affinity DataEC50:  9.30E+4nMAssay Description:A radiolabeled ligand competition scintillation proximity assay (SPA) for the androgen receptor (AR) using Ni-coated 384-well FlashPlates. It measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
St. Jude Research Hospital

LigandPNGBDBM17636(2-{[3-(trifluoromethyl)phenyl]amino}benzoic acid |...)
Affinity DataEC50:  6.70E+4nMAssay Description:A radiolabeled ligand competition scintillation proximity assay (SPA) for the androgen receptor (AR) using Ni-coated 384-well FlashPlates. It measure...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAndrogen receptor [646-919](Human)
Karlsruhe Institute of Technology

LigandPNGBDBM227645(MAQRGGARRPRGDRERLGSR | Bag-1L (1-20))
Affinity DataKd:  2.00E+3nMpH: 6.5Assay Description:For the fluorescence polarization experiments, 5 nM fluorescently labeled Bag-1L (Bag-1L(1-20), fluorescein isothiocyanate (FITC)-MAQRGGARRPRGDRERLGS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2017
Entry Details Article
PubMed
TargetAndrogen receptor [646-919](Human)
Karlsruhe Institute of Technology

LigandPNGBDBM227646(RGAAAGARRPRMKKKTRRRS | Bag-1L (61-80))
Affinity DataKd:  3.30E+3nMpH: 6.5Assay Description:For the fluorescence polarization experiments, 5 nM fluorescently labeled Bag-1L (Bag-1L(1-20), fluorescein isothiocyanate (FITC)-MAQRGGARRPRGDRERLGS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2017
Entry Details Article
PubMed
TargetAndrogen receptor [646-919](Human)
Karlsruhe Institute of Technology

LigandPNGBDBM227647(HDSKGQTKLLQLLTTKSDQM | SCR-2 peptide)
Affinity DataKd:  2.80E+3nMpH: 6.5Assay Description:For the fluorescence polarization experiments, 5 nM fluorescently labeled Bag-1L (Bag-1L(1-20), fluorescein isothiocyanate (FITC)-MAQRGGARRPRGDRERLGS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2017
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
St. Jude Research Hospital

LigandPNGBDBM50403730(CHEMBL2052002)
Affinity DataEC50:  5nMAssay Description:In vitro agonistic activity against human androgen receptor using cotransfection assay in CV-1 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
St. Jude Research Hospital

LigandPNGBDBM50403727(CHEMBL2112310)
Affinity DataEC50:  1.40E+3nMAssay Description:In vitro antagonistic activity against human androgen receptor (hAR) expressed in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
St. Jude Research Hospital

LigandPNGBDBM18161(DHT | Dihydrotestosterone | [3H]DHT | (5alpha,17be...)
Affinity DataEC50:  6nMAssay Description:In vitro agonistic activity against human androgen receptor using cotransfection assay in CV-1 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAndrogen receptor(Human)
St. Jude Research Hospital

LigandPNGBDBM50076689(5-Ethyl-8-methyl-4-trifluoromethyl-5,6,7,8-tetrahy...)
Affinity DataEC50:  209nMAssay Description:In vitro agonistic activity against human androgen receptor using cotransfection assay in CV-1 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
St. Jude Research Hospital

LigandPNGBDBM50076685(7-Ethyl-6-methyl-4-trifluoromethyl-5,6,7,8-tetrahy...)
Affinity DataEC50:  1nMAssay Description:In vitro agonistic activity against human androgen receptor using cotransfection assay in CV-1 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
St. Jude Research Hospital

LigandPNGBDBM50076712((7S,8R)-8-Ethyl-7-propyl-4-trifluoromethyl-6,7,8,9...)
Affinity DataEC50:  16nMAssay Description:Agonistic activity against human androgen receptor (hAR) expressed in CV-1 cell linesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
St. Jude Research Hospital

LigandPNGBDBM50076717((R)-8-Methyl-4-trifluoromethyl-6,7,8,9-tetrahydro-...)
Affinity DataEC50:  21nMAssay Description:Agonistic activity against human androgen receptor (hAR) expressed in CV-1 cell linesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
St. Jude Research Hospital

LigandPNGBDBM50076713((7S,8R)-7-Ethyl-8-methyl-4-trifluoromethyl-6,7,8,9...)
Affinity DataEC50:  9nMAssay Description:Agonistic activity against human androgen receptor (hAR) expressed in CV-1 cell linesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
St. Jude Research Hospital

LigandPNGBDBM50076706((7R,8R)-7-Ethyl-8-methyl-4-trifluoromethyl-6,7,8,9...)
Affinity DataEC50:  10nMAssay Description:Agonistic activity against human androgen receptor (hAR) expressed in CV-1 cell linesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
St. Jude Research Hospital

LigandPNGBDBM50076692(5-Propyl-4-trifluoromethyl-5,6,7,8-tetrahydro-1-ox...)
Affinity DataEC50:  5nMAssay Description:In vitro agonistic activity against human androgen receptor using cotransfection assay in CV-1 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
St. Jude Research Hospital

LigandPNGBDBM50077113(6-Propyl-4-trifluoromethyl-6,7,8,9-tetrahydro-1H-p...)
Affinity DataEC50:  19nMAssay Description:Agonist activity to the human androgen receptor (hAR) in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
St. Jude Research Hospital

LigandPNGBDBM50069068((R)-2-Methyl-5-trifluoromethyl-1,2,3,8-tetrahydro-...)
Affinity DataEC50:  168nMAssay Description:Agonistic activity (EC50) against human androgen receptor (hAR) in co-transfected CV-1 cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
St. Jude Research Hospital

LigandPNGBDBM50069079((S)-3-Methyl-5-trifluoromethyl-1,2,3,8-tetrahydro-...)
Affinity DataEC50:  62nMAssay Description:Agonistic activity (EC50) against human androgen receptor (hAR) in co-transfected CV-1 cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
St. Jude Research Hospital

LigandPNGBDBM50077107(6-Ethyl-9-methyl-4-trifluoromethyl-6,7,8,9-tetrahy...)
Affinity DataEC50:  158nMAssay Description:Agonist activity to the human androgen receptor (hAR) in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
St. Jude Research Hospital

LigandPNGBDBM50077097(6-Methyl-4-trifluoromethyl-6,7,8,9-tetrahydro-1H-p...)
Affinity DataEC50:  15nMAssay Description:Agonist activity to the human androgen receptor (hAR) in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
St. Jude Research Hospital

LigandPNGBDBM50077109(6-Isopropyl-4-trifluoromethyl-6,7,8,9-tetrahydro-1...)
Affinity DataEC50:  3nMAssay Description:Agonist activity to the human androgen receptor (hAR) in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
St. Jude Research Hospital

LigandPNGBDBM18161(DHT | Dihydrotestosterone | [3H]DHT | (5alpha,17be...)
Affinity DataEC50:  5nMAssay Description:Agonist activity against Human Androgen receptor expressed in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAndrogen receptor(Human)
St. Jude Research Hospital

LigandPNGBDBM18190(Compound 3c | 6-ethyl-4-(trifluoromethyl)-1H,2H,6H...)
Affinity DataEC50:  4nMAssay Description:Agonist activity against Human Androgen receptor expressed in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
St. Jude Research Hospital

LigandPNGBDBM50076687(5-Methyl-4-trifluoromethyl-5,6,7,8-tetrahydro-1-ox...)
Affinity DataEC50:  2nMAssay Description:In vitro agonistic activity against human androgen receptor using cotransfection assay in CV-1 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
St. Jude Research Hospital

LigandPNGBDBM50076684(4,5-Bis-trifluoromethyl-5,6,7,8-tetrahydro-1-oxa-8...)
Affinity DataEC50:  2nMAssay Description:In vitro agonistic activity against human androgen receptor using cotransfection assay in CV-1 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
St. Jude Research Hospital

LigandPNGBDBM50076694(5-Pentafluoroethyl-4-trifluoromethyl-5,6,7,8-tetra...)
Affinity DataEC50:  13nMAssay Description:In vitro agonistic activity against human androgen receptor using cotransfection assay in CV-1 cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Mouse)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50067678(17-Acetoxy-6alpha-methylprogesterone | 17alpha-Hyd...)
Affinity DataEC50:  6.10nMAssay Description:Effective concentration against Androgen receptor in mouse fibroblast L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
St. Jude Research Hospital

LigandPNGBDBM50073060((9R,10S,11S,13S,17S)-9-Fluoro-11,17-dihydroxy-10,1...)
Affinity DataEC50:  0.300nMAssay Description:Agonist activity against Human Androgen receptor expressed in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
St. Jude Research Hospital

LigandPNGBDBM50131268(4-[1-(4-Dibutylamino-phenyl)-meth-(Z)-ylidene]-3-p...)
Affinity DataKd:  1.40nMAssay Description:Dissociation constant against GST-hARLBD was measured in SC-3 cell by using [3H]testosterone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
St. Jude Research Hospital

LigandPNGBDBM50131271(3-(4-Hydroxy-phenyl)-4-[1-(4-pyrrolidin-1-yl-pheny...)
Affinity DataKd:  1.40nMAssay Description:Dissociation constant against GST-hARLBD was measured in SC-3 cell by using [3H]testosterone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
St. Jude Research Hospital

LigandPNGBDBM50131269(3-(2-Fluoro-phenyl)-4-[1-(4-pyrrolidin-1-yl-phenyl...)
Affinity DataKd:  1.40nMAssay Description:Dissociation constant against GST-hARLBD was measured in SC-3 cell by using [3H]testosterone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
St. Jude Research Hospital

LigandPNGBDBM50131272(3-(4-Fluoro-phenyl)-4-[1-(4-pyrrolidin-1-yl-phenyl...)
Affinity DataKd:  1.40nMAssay Description:Dissociation constant against GST-hARLBD was measured in SC-3 cell by using [3H]testosterone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
St. Jude Research Hospital

LigandPNGBDBM50205096(2-chloro-4-((7R,7aS)-7-hydroxy-1,3-dioxo-tetrahydr...)
Affinity DataEC50:  2.80nMAssay Description:Agonist activity at human ARMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
St. Jude Research Hospital

LigandPNGBDBM50205098(4-((7R,7aS)-7-hydroxy-1,3-dioxo-tetrahydro-1H-pyrr...)
Affinity DataEC50:  1.70nMAssay Description:Agonist activity at human ARMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
St. Jude Research Hospital

LigandPNGBDBM50205099(4-((7R,7aS)-7-hydroxy-1,3-dioxo-tetrahydro-1H-pyrr...)
Affinity DataEC50:  221nMAssay Description:Agonist activity at human ARMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
St. Jude Research Hospital

LigandPNGBDBM50205100(4-((7R,7aS)-7-hydroxy-1,3-dioxo-tetrahydro-1H-pyrr...)
Affinity DataEC50:  3.60nMAssay Description:Agonist activity at human ARMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
St. Jude Research Hospital

LigandPNGBDBM50205101(4-((7R,7aS)-7-hydroxy-1,3-dioxo-tetrahydro-1H-pyrr...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human ARMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
St. Jude Research Hospital

LigandPNGBDBM50205102(3-ethyl-4-((7R,7aS)-7-hydroxy-1,3-dioxo-tetrahydro...)
Affinity DataEC50:  36nMAssay Description:Agonist activity at human ARMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
St. Jude Research Hospital

LigandPNGBDBM50205097(3-ethyl-4-((7R,7aS)-7-hydroxy-1,3-dioxo-tetrahydro...)
Affinity DataEC50:  79nMAssay Description:Agonist activity at human ARMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
St. Jude Research Hospital

LigandPNGBDBM50205105(4-((7R,7aS)-7-hydroxy-1,3-dioxo-tetrahydro-1H-pyrr...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human ARMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
St. Jude Research Hospital

LigandPNGBDBM18171(hydantoin, 7 | 4-[(7R,7aS)-7-hydroxy-1,3-dioxo-hex...)
Affinity DataEC50:  2.30nMAssay Description:Agonist activity at human ARMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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