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Report error Found 152 Enz. Inhib. hit(s) with Target = 'Bcl2-associated agonist of cell death'
TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM50060993(4'-Fluoro-biphenyl-4-carboxylic acid | 4'-FLUORO-1...)
Affinity DataKd:  4.00E+5nMAssay Description:Binding affinity to BH3 binding groove of BclXLMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM50270875(5,6,7,8-tetrahydro-1-naphthol | CHEMBL449132)
Affinity DataKd:  2.00E+6nMAssay Description:Binding affinity to BH3 binding groove of BclXLMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBcl2-associated agonist of cell death(Mouse)
Entremed

Curated by ChEMBL
LigandPNGBDBM50263298(2-((2S,3R,4S)-4-(allyloxycarbonyl)-1-benzoyl-3-hyd...)
Affinity DataKd:  4.00E+6nMAssay Description:Binding affinity to mouse Bcl-XL expressed in Escherichia coli BL21 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBcl2-associated agonist of cell death(Mouse)
Entremed

Curated by ChEMBL
LigandPNGBDBM50262597([(2S,3R,4S)-1-(Biphenyl-4-carbonyl)-4-[(biphenyl-4...)
Affinity DataKd:  7.00E+4nMAssay Description:Binding affinity to mouse Bcl-XL expressed in Escherichia coli BL21 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBcl2-associated agonist of cell death(Mouse)
Entremed

Curated by ChEMBL
LigandPNGBDBM50262596(2-((2S,3R,4S)-4-(2-naphthamido)-1-(2-naphthoyl)-3-...)
Affinity DataKd:  1.00E+6nMAssay Description:Binding affinity to mouse Bcl-XL expressed in Escherichia coli BL21 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBcl2-associated agonist of cell death(Mouse)
Entremed

Curated by ChEMBL
LigandPNGBDBM50262595(2-((2S,3R,4S)-4-benzamido-1-benzoyl-3-hydroxy-6-((...)
Affinity DataKd: >5.00E+6nMAssay Description:Binding affinity to mouse Bcl-XL expressed in Escherichia coli BL21 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBcl2-associated agonist of cell death(Mouse)
Entremed

Curated by ChEMBL
LigandPNGBDBM50262594((2S,3R,4S)-4-[(Biphenyl-4-carbonyl)-amino]-2-carbo...)
Affinity DataKd:  1.00E+5nMAssay Description:Binding affinity to mouse Bcl-XL expressed in Escherichia coli BL21 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBcl2-associated agonist of cell death(Mouse)
Entremed

Curated by ChEMBL
LigandPNGBDBM50262593(2-((2S,3R,4S)-4-(2-naphthamido)-3-hydroxy-6-((2-me...)
Affinity DataKd:  2.00E+5nMAssay Description:Binding affinity to mouse Bcl-XL expressed in Escherichia coli BL21 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBcl2-associated agonist of cell death(Mouse)
Entremed

Curated by ChEMBL
LigandPNGBDBM50262592(2-((2S,3R,4S)-4-benzamido-3-hydroxy-6-((2-methoxye...)
Affinity DataKd:  3.00E+5nMAssay Description:Binding affinity to mouse Bcl-XL expressed in Escherichia coli BL21 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBcl2-associated agonist of cell death(Mouse)
Entremed

Curated by ChEMBL
LigandPNGBDBM50262591([(2S,3R,4S)-4-Allyloxycarbonylamino-1-(biphenyl-4-...)
Affinity DataKd:  1.00E+5nMAssay Description:Binding affinity to mouse Bcl-XL expressed in Escherichia coli BL21 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBcl2-associated agonist of cell death(Mouse)
Entremed

Curated by ChEMBL
LigandPNGBDBM50262590(2-((2S,3R,4S)-1-(2-naphthoyl)-4-(allyloxycarbonyl)...)
Affinity DataKd:  1.00E+6nMAssay Description:Binding affinity to mouse Bcl-XL expressed in Escherichia coli BL21 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM50357587(CHEMBL1915438)
Affinity DataEC50:  30nMAssay Description:Inhibition of BAD phosphorylation at Ser112 in human MV-4-11 cells assessed as phospho-BAD level after 4 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM50357591(CHEMBL1915442)
Affinity DataEC50:  140nMAssay Description:Inhibition of BAD phosphorylation at Ser112 in human MV-4-11 cells assessed as phospho-BAD level after 4 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM50357594(CHEMBL1915445)
Affinity DataEC50:  90nMAssay Description:Inhibition of BAD phosphorylation at Ser112 in human MV-4-11 cells assessed as phospho-BAD level after 4 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM50357597(CHEMBL1915448)
Affinity DataEC50:  50nMAssay Description:Inhibition of BAD phosphorylation at Ser112 in human MV-4-11 cells assessed as phospho-BAD level after 4 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM50357598(CHEMBL1915449)
Affinity DataEC50:  30nMAssay Description:Inhibition of BAD phosphorylation at Ser112 in human MV-4-11 cells assessed as phospho-BAD level after 4 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM50357599(CHEMBL1915633)
Affinity DataEC50:  1.58E+3nMAssay Description:Inhibition of BAD phosphorylation at Ser112 in human MV-4-11 cells assessed as phospho-BAD level after 4 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM50357602(CHEMBL1915636)
Affinity DataEC50:  530nMAssay Description:Inhibition of BAD phosphorylation at Ser112 in human MV-4-11 cells assessed as phospho-BAD level after 4 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM50357607(CHEMBL1915641)
Affinity DataEC50:  40nMAssay Description:Inhibition of BAD phosphorylation at Ser112 in human MV-4-11 cells assessed as phospho-BAD level after 4 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM50357610(CHEMBL1915644)
Affinity DataEC50:  1.02E+3nMAssay Description:Inhibition of BAD phosphorylation at Ser112 in human MV-4-11 cells assessed as phospho-BAD level after 4 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM50357611(CHEMBL1915645)
Affinity DataEC50:  100nMAssay Description:Inhibition of BAD phosphorylation at Ser112 in human MV-4-11 cells assessed as phospho-BAD level after 4 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM50357612(CHEMBL1915646)
Affinity DataEC50:  210nMAssay Description:Inhibition of BAD phosphorylation at Ser112 in human MV-4-11 cells assessed as phospho-BAD level after 4 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM50357613(CHEMBL1915647)
Affinity DataEC50:  890nMAssay Description:Inhibition of BAD phosphorylation at Ser112 in human MV-4-11 cells assessed as phospho-BAD level after 4 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM50357614(CHEMBL1915648)
Affinity DataEC50:  980nMAssay Description:Inhibition of BAD phosphorylation at Ser112 in human MV-4-11 cells assessed as phospho-BAD level after 4 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM50357616(CHEMBL1915650)
Affinity DataEC50:  200nMAssay Description:Inhibition of BAD phosphorylation at Ser112 in human MV-4-11 cells assessed as phospho-BAD level after 4 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM50357617(CHEMBL1915651)
Affinity DataEC50:  100nMAssay Description:Inhibition of BAD phosphorylation at Ser112 in human MV-4-11 cells assessed as phospho-BAD level after 4 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM50357618(CHEMBL1914471)
Affinity DataEC50:  760nMAssay Description:Inhibition of BAD phosphorylation at Ser112 in human MV-4-11 cells assessed as phospho-BAD level after 4 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM552906(2-(1H-Pyrrolo[2,3-b]pyridin-5-yl-oxy)-4-(4-((2-(3-...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan platform: T7 phage strains displaying BCL2 proteins were grown i...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM552907(2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)-4-(4-((4,4-di...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan platform: T7 phage strains displaying BCL2 proteins were grown i...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM552908(US11344546, Example 10 | 2-(1H-pyrrolo[2,3-b]pyrid...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan platform: T7 phage strains displaying BCL2 proteins were grown i...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM552909(US11318134, Example 11 | US11344546, Example 11 | ...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan platform: T7 phage strains displaying BCL2 proteins were grown i...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM552910(US11344546, Example 13 | US11590126, Example 13 | ...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan platform: T7 phage strains displaying BCL2 proteins were grown i...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM552911(US11344546, Example 15 | US11590126, Example 15 | ...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan platform: T7 phage strains displaying BCL2 proteins were grown i...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM552912(US11344546, Example 16 | US11590126, Example 16 | ...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan platform: T7 phage strains displaying BCL2 proteins were grown i...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM552913(US11344546, Example 17 | US11590126, Example 17 | ...)
Affinity DataKd:  55nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan platform: T7 phage strains displaying BCL2 proteins were grown i...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM552914(US11344546, Example 20 | US11590126, Example 20 | ...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan platform: T7 phage strains displaying BCL2 proteins were grown i...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM555311(US11344546, Example 23 | 2-(1H-pyrrolo[2,3-b]pyrid...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan platform: T7 phage strains displaying BCL2 proteins were grown i...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM555312(US11344546, Example 25 | 2-((1H-pyrrolo[2,3-b]pyri...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan platform: T7 phage strains displaying BCL2 proteins were grown i...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM555313(US11344546, Example 26 | 2-((1H-pyrrolo[2,3-b]pyri...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan platform: T7 phage strains displaying BCL2 proteins were grown i...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM555314(US11344546, Example 27 | 2-((1H-pyrrolo[2,3-b]pyri...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan platform: T7 phage strains displaying BCL2 proteins were grown i...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM555315(US11344546, Example 28 | 2-((1H-pyrrolo[2,3-b]pyri...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan platform: T7 phage strains displaying BCL2 proteins were grown i...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM555316(US11344546, Example 30 | 2-((1H-pyrrolo[2,3-b]pyri...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan platform: T7 phage strains displaying BCL2 proteins were grown i...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM555317(US11344546, Example 31 | 2-((1H-pyrrolo[2,3-b]pyri...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan platform: T7 phage strains displaying BCL2 proteins were grown i...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM555318(US11344546, Example 32 | 2-((1H-pyrrolo[2,3-b]pyri...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan platform: T7 phage strains displaying BCL2 proteins were grown i...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM552923(US11318134, Example 33 | BDBM595424 | BDBM555319 |...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan platform: T7 phage strains displaying BCL2 proteins were grown i...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM555320(US11344546, Example 34 | 2-((1H-pyrrolo[2,3-b]pyri...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan platform: T7 phage strains displaying BCL2 proteins were grown i...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM552925(US11318134, Example 35 | BDBM595426 | 2-((1H-pyrro...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan platform: T7 phage strains displaying BCL2 proteins were grown i...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM552926(US11318134, Example 36 | BDBM595427 | BDBM555322 |...)
Affinity DataKd:  55nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan platform: T7 phage strains displaying BCL2 proteins were grown i...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM552927(BDBM595428 | BDBM555323 | US11318134, Example 38 |...)
Affinity DataKd:  55nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan platform: T7 phage strains displaying BCL2 proteins were grown i...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetBcl2-associated agonist of cell death(Human)
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM555324(US11344546, Example 39 | 2-((1H-pyrrolo[2,3-b]pyri...)
Affinity DataKd: >100nMAssay Description:Table 1: Binding to Bcl-2 proteins Bcl-2, and Bcl-XL was assessed using the Bcl2scan platform: T7 phage strains displaying BCL2 proteins were grown i...More data for this Ligand-Target Pair
In DepthDetails
US Patent

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