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Report error Found 73 Enz. Inhib. hit(s) with Target = 'Bile salt-activated lipase'
TargetBile salt-activated lipase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50286879(Butyl-carbamic acid 2'-butylcarbamoyloxy-[1,1']bin...)
Affinity DataKoff:  4.00E+3s-1Assay Description:Bimolecular rate constant (ki) for the Pancreatic cholesterol esterase-catalyzed hydrolysis of 4-nitrophenyl butyrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetBile salt-activated lipase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50286880(Butyric acid 2'-butylcarbamoyloxy-[1,1']binaphthal...)
Affinity DataKoff:  6.00E+3s-1Assay Description:Bimolecular rate constant (ki) for the Pancreatic cholesterol esterase-catalyzed hydrolysis of 4-nitrophenyl butyrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetBile salt-activated lipase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50286880(Butyric acid 2'-butylcarbamoyloxy-[1,1']binaphthal...)
Affinity DataKoff:  6.00E+3s-1Assay Description:Bimolecular rate constant (ki) for the Pancreatic cholesterol esterase-catalyzed hydrolysis of 4-nitrophenyl butyrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetBile salt-activated lipase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50286880(Butyric acid 2'-butylcarbamoyloxy-[1,1']binaphthal...)
Affinity DataKoff:  6.00E+3s-1Assay Description:Bimolecular rate constant (ki) for the Pancreatic cholesterol esterase-catalyzed hydrolysis of 4-nitrophenyl butyrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetBile salt-activated lipase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50286878(Butyl-carbamic acid 2'-hydroxy-[1,1']binaphthaleny...)
Affinity DataKoff:  5.00E+5s-1Assay Description:Bimolecular rate constant (ki) for the Pancreatic cholesterol esterase-catalyzed hydrolysis of 4-nitrophenyl butyrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetBile salt-activated lipase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50286878(Butyl-carbamic acid 2'-hydroxy-[1,1']binaphthaleny...)
Affinity DataKoff:  5.00E+5s-1Assay Description:Bimolecular rate constant (ki) for the Pancreatic cholesterol esterase-catalyzed hydrolysis of 4-nitrophenyl butyrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetBile salt-activated lipase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50286878(Butyl-carbamic acid 2'-hydroxy-[1,1']binaphthaleny...)
Affinity DataKoff:  5.00E+5s-1Assay Description:Bimolecular rate constant (ki) for the Pancreatic cholesterol esterase-catalyzed hydrolysis of 4-nitrophenyl butyrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetBile salt-activated lipase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50286879(Butyl-carbamic acid 2'-butylcarbamoyloxy-[1,1']bin...)
Affinity DataKoff:  4.00E+3s-1Assay Description:Bimolecular rate constant (ki) for the Pancreatic cholesterol esterase-catalyzed hydrolysis of 4-nitrophenyl butyrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetBile salt-activated lipase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50286879(Butyl-carbamic acid 2'-butylcarbamoyloxy-[1,1']bin...)
Affinity DataKoff:  4.00E+3s-1Assay Description:Bimolecular rate constant (ki) for the Pancreatic cholesterol esterase-catalyzed hydrolysis of 4-nitrophenyl butyrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetBile salt-activated lipase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM24567(Tetrahydrolipstatin | CHEMBL175247 | Xenical | (2S...)
Affinity DataIC50: 423nMAssay Description:Inhibition of Sus scrofa (pig) pancreatic lipase type 2 using PNPB as substrate pre-incubated with enzyme for 5 min prior to substrate addition measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article

TargetBile salt-activated lipase(Human)
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50244756(2-(2,3,5,6-Tetrafluoropyridin-4-yl)-1,2-benzisothi...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of cholesterol esteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBile salt-activated lipase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50480308(Dihydroberberine)
Affinity DataIC50: 2.37E+4nMAssay Description:Inhibition of Sus scrofa (pig) pancreatic lipase type 2 using PNPB as substrate pre-incubated with enzyme for 5 min prior to substrate addition measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article

TargetBile salt-activated lipase(Human)
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50244755(2-(Pyridin-4-yl)-4,5,6,7-tetrahydro-1,2-benzisothi...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of cholesterol esteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBile salt-activated lipase(Human)
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50244703(2-(6-Chloropyridin-2-yl)-4,5,6,7-tetrahydro-1,2-be...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of cholesterol esteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBile salt-activated lipase(Human)
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50244754(2-(2,3,4,5,6-Pentafluorophenyl)-4,5,6,7-tetrahydro...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of cholesterol esteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBile salt-activated lipase(Human)
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50244753(5-Methyl-4-phenyl-2-(2,3,5,6-tetrafluoropyridin-4-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of cholesterol esteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBile salt-activated lipase(Human)
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50244752(4,5-Dimethyl-2-(2,3,5,6-tetrafluoropyridin-4-yl)-i...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of cholesterol esteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBile salt-activated lipase(Human)
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50244751(2-(2,3,5,6-Tetrafluoropyridin-4-yl)-4,5,6,7-tetrah...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of cholesterol esteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBile salt-activated lipase(Human)
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50244705(2-(3,5-Difluoropyridin-2-yl)-4,5,6,7-tetrahydro-1,...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of cholesterol esteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBile salt-activated lipase(Human)
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50244704(2-(6-Bromopyridin-2-yl)-4,5,6,7-tetrahydro-1,2-ben...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of cholesterol esteraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetBile salt-activated lipase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50203126(Berberinechloride | 9,10-Dimethoxy-5,6-dihydro-[1,...)
Affinity DataIC50: 3.15E+5nMAssay Description:Inhibition of Sus scrofa (pig) pancreatic lipase type 2 using PNPB as substrate pre-incubated with enzyme for 5 min prior to substrate addition measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article

TargetBile salt-activated lipase(Human)
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50081700(6-Chloro-3-(2-cyclohexyl-ethyl)-pyran-2-one | CHEM...)
Affinity DataKi:  25nMAssay Description:Inhibition of the Pancreatic Cholesterol Esterase from porcineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBile salt-activated lipase(Human)
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50081696(6-Chloro-3-cyclopentyl-pyran-2-one | CHEMBL133091)
Affinity DataKi:  40nMAssay Description:Inhibition of the Pancreatic Cholesterol Esterase from porcineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBile salt-activated lipase(Human)
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50081698(6-Chloro-5-(2-cyclohexyl-ethyl)-pyran-2-one | CHEM...)
Affinity DataKi:  58nMAssay Description:Inhibition of the Pancreatic Cholesterol Esterase from porcineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBile salt-activated lipase(Human)
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50081697(6-Chloro-3-(3-cyclohexyl-propyl)-pyran-2-one | CHE...)
Affinity DataKi:  60nMAssay Description:Inhibition of the Pancreatic Cholesterol Esterase from porcineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBile salt-activated lipase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50084233(2-Diethylamino-6,7-dihydro-5H-cyclopenta[4,5]thien...)
Affinity DataKi:  580nMAssay Description:Inhibitory activity against bovine pancreatic CEase in presence of pNPB chromogenic substrate by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBile salt-activated lipase(Human)
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50081695(6-Chloro-3-(4-cyclohexyl-butyl)-pyran-2-one | CHEM...)
Affinity DataKi:  580nMAssay Description:Inhibition of the Pancreatic Cholesterol Esterase from porcineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBile salt-activated lipase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50179322(6,7-dihydro-2-(dimethylamino)-4H,5H-cyclopenta[4,5...)
Affinity DataKi:  630nMAssay Description:Inhibitory activity against bovine pancreatic CEase in presence of pNPB chromogenic substrate by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBile salt-activated lipase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50286878(Butyl-carbamic acid 2'-hydroxy-[1,1']binaphthaleny...)
Affinity DataKi:  800nMAssay Description:Dissociation constant (KI) for the Pancreatic cholesterol esterase-catalyzed hydrolysis of 4-nitrophenyl butyrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetBile salt-activated lipase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50286878(Butyl-carbamic acid 2'-hydroxy-[1,1']binaphthaleny...)
Affinity DataKi:  800nMAssay Description:Dissociation constant (KI) for the Pancreatic cholesterol esterase-catalyzed hydrolysis of 4-nitrophenyl butyrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetBile salt-activated lipase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50286878(Butyl-carbamic acid 2'-hydroxy-[1,1']binaphthaleny...)
Affinity DataKi:  800nMAssay Description:Dissociation constant (KI) for the Pancreatic cholesterol esterase-catalyzed hydrolysis of 4-nitrophenyl butyrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetBile salt-activated lipase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50084229(2-Diethylamino-5-methyl-5,6,7,8-tetrahydro-benzo[4...)
Affinity DataKi:  1.64E+3nMAssay Description:Inhibitory activity against bovine pancreatic CEase in presence of pNPB chromogenic substrate by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBile salt-activated lipase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50064308(2-Diethylamino-5,6,7,8-tetrahydro-benzo[4,5]thieno...)
Affinity DataKi:  1.86E+3nMAssay Description:Inhibitory activity against bovine pancreatic CEase in presence of pNPB chromogenic substrate by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBile salt-activated lipase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50179331(5,6,7,8-tetrahydro-2-(dimethylamino)-4H-benzo[4,5]...)
Affinity DataKi:  2.15E+3nMAssay Description:Inhibitory activity against bovine pancreatic CEase in presence of pNPB chromogenic substrate by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBile salt-activated lipase(Human)
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50081694(6-Chloro-3-cyclohexylmethyl-pyran-2-one | CHEMBL44...)
Affinity DataKi:  2.20E+3nMAssay Description:Inhibition of the Pancreatic Cholesterol Esterase from porcineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBile salt-activated lipase(Human)
University of Leipzig

Curated by ChEMBL
LigandPNGBDBM50081699(6-Chloro-3-cyclohexyl-pyran-2-one | CHEMBL134790)
Affinity DataKi:  2.30E+3nMAssay Description:Inhibition of the Pancreatic Cholesterol Esterase from porcineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBile salt-activated lipase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50179326(2-Diethylamino-5,6-dimethyl-thieno[2,3-d][1,3]oxaz...)
Affinity DataKi:  4.30E+3nMAssay Description:Inhibitory activity against bovine pancreatic CEase in presence of pNPB chromogenic substrate by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBile salt-activated lipase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50179329(2-morpholin-4-yl-5,6,7,8-tetrahydro-benzo[4,5]thie...)
Affinity DataKi:  5.70E+3nMAssay Description:Inhibitory activity against bovine pancreatic CEase in presence of pNPB chromogenic substrate by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBile salt-activated lipase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50179318(2-dimethylamino-5,8-dihydro-4H,6H-thiopyrano[4',3'...)
Affinity DataKi:  5.76E+3nMAssay Description:Inhibitory activity against bovine pancreatic CEase in presence of pNPB chromogenic substrate by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBile salt-activated lipase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50084234(2-Diethylamino-6,7,8,9-tetrahydro-5H-3-oxa-10-thia...)
Affinity DataKi:  6.00E+3nMAssay Description:Inhibitory activity against bovine pancreatic CEase in presence of pNPB chromogenic substrate by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBile salt-activated lipase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50084232(2-Diethylamino-5-isopropyl-thieno[2,3-d][1,3]oxazi...)
Affinity DataKi:  6.40E+3nMAssay Description:Inhibitory activity against bovine pancreatic CEase in presence of pNPB chromogenic substrate by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBile salt-activated lipase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50084235(2-Diethylamino-benzo[4,5]thieno[2,3-d][1,3]oxazin-...)
Affinity DataKi:  7.50E+3nMAssay Description:Inhibitory activity against bovine pancreatic CEase in presence of pNPB chromogenic substrate by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBile salt-activated lipase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50286880(Butyric acid 2'-butylcarbamoyloxy-[1,1']binaphthal...)
Affinity DataKi:  9.00E+3nMAssay Description:Dissociation constant (KI) for the Pancreatic cholesterol esterase-catalyzed hydrolysis of 4-nitrophenyl butyrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetBile salt-activated lipase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50084228(2-(diethylamino)-5-methyl-4H-thieno[2,3-d][1,3]oxa...)
Affinity DataKi:  1.50E+4nMAssay Description:Inhibitory activity against bovine pancreatic CEase in presence of pNPB chromogenic substrate by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBile salt-activated lipase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50179311(2-(cyclohexyl-methyl-amino)-5,6,7,8-tetrahydro-ben...)
Affinity DataKi:  1.80E+4nMAssay Description:Inhibitory activity against bovine pancreatic CEase in presence of pNPB chromogenic substrate by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBile salt-activated lipase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50286880(Butyric acid 2'-butylcarbamoyloxy-[1,1']binaphthal...)
Affinity DataKi:  2.00E+4nMAssay Description:Dissociation constant (KI) for the Pancreatic cholesterol esterase-catalyzed hydrolysis of 4-nitrophenyl butyrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetBile salt-activated lipase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50286880(Butyric acid 2'-butylcarbamoyloxy-[1,1']binaphthal...)
Affinity DataKi:  2.00E+4nMAssay Description:Bimolecular rate constant (ki) for the Pancreatic cholesterol esterase-catalyzed hydrolysis of 4-nitrophenyl butyrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetBile salt-activated lipase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50286879(Butyl-carbamic acid 2'-butylcarbamoyloxy-[1,1']bin...)
Affinity DataKi:  2.90E+4nMAssay Description:Dissociation constant (KI) for the Pancreatic cholesterol esterase-catalyzed hydrolysis of 4-nitrophenyl butyrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetBile salt-activated lipase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50286879(Butyl-carbamic acid 2'-butylcarbamoyloxy-[1,1']bin...)
Affinity DataKi:  3.00E+4nMAssay Description:Dissociation constant (KI) for the Pancreatic cholesterol esterase-catalyzed hydrolysis of 4-nitrophenyl butyrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetBile salt-activated lipase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50286879(Butyl-carbamic acid 2'-butylcarbamoyloxy-[1,1']bin...)
Affinity DataKi:  3.00E+4nMAssay Description:Dissociation constant (KI) for the Pancreatic cholesterol esterase-catalyzed hydrolysis of 4-nitrophenyl butyrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

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